---
res:
  bibo_abstract:
  - The formation of neuronal dendrite branches is fundamental for the wiring and
    function of the nervous system. Indeed, dendrite branching enhances the coverage
    of the neuron's receptive field and modulates the initial processing of incoming
    stimuli. Complex dendrite patterns are achieved in vivo through a dynamic process
    of de novo branch formation, branch extension and retraction. The first step towards
    branch formation is the generation of a dynamic filopodium-like branchlet. The
    mechanisms underlying the initiation of dendrite branchlets are therefore crucial
    to the shaping of dendrites. Through in vivo time-lapse imaging of the subcellular
    localization of actin during the process of branching of Drosophila larva sensory
    neurons, combined with genetic analysis and electron tomography, we have identified
    the Actin-related protein (Arp) 2/3 complex as the major actin nucleator involved
    in the initiation of dendrite branchlet formation, under the control of the activator
    WAVE and of the small GTPase Rac1. Transient recruitment of an Arp2/3 component
    marks the site of branchlet initiation in vivo. These data position the activation
    of Arp2/3 as an early hub for the initiation of branchlet formation.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Tomke
      foaf_name: Stürner, Tomke
      foaf_surname: Stürner
  - foaf_Person:
      foaf_givenName: Anastasia
      foaf_name: Tatarnikova, Anastasia
      foaf_surname: Tatarnikova
  - foaf_Person:
      foaf_givenName: Jan
      foaf_name: Müller, Jan
      foaf_surname: Müller
      foaf_workInfoHomepage: http://www.librecat.org/personId=AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D
  - foaf_Person:
      foaf_givenName: Barbara
      foaf_name: Schaffran, Barbara
      foaf_surname: Schaffran
  - foaf_Person:
      foaf_givenName: Hermann
      foaf_name: Cuntz, Hermann
      foaf_surname: Cuntz
  - foaf_Person:
      foaf_givenName: Yun
      foaf_name: Zhang, Yun
      foaf_surname: Zhang
  - foaf_Person:
      foaf_givenName: Maria
      foaf_name: Nemethova, Maria
      foaf_surname: Nemethova
      foaf_workInfoHomepage: http://www.librecat.org/personId=34E27F1C-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Sven
      foaf_name: Bogdan, Sven
      foaf_surname: Bogdan
  - foaf_Person:
      foaf_givenName: Vic
      foaf_name: Small, Vic
      foaf_surname: Small
  - foaf_Person:
      foaf_givenName: Gaia
      foaf_name: Tavosanis, Gaia
      foaf_surname: Tavosanis
  bibo_doi: 10.1242/dev.171397
  bibo_issue: '7'
  bibo_volume: 146
  dct_date: 2019^xs_gYear
  dct_identifier:
  - UT:000464583200006
  dct_isPartOf:
  - http://id.crossref.org/issn/0950-1991
  - http://id.crossref.org/issn/1477-9129
  dct_language: eng
  dct_publisher: The Company of Biologists@
  dct_title: Transient localization of the Arp2/3 complex initiates neuronal dendrite
    branching in vivo@
  fabio_hasPubmedId: '30910826'
...