---
res:
  bibo_abstract:
  - The BH3-only family of proteins is key for initiating apoptosis in a variety of
    contexts, and may also contribute to non-apoptotic cellular processes. Historically,
    the nematode Caenorhabditis elegans has provided a powerful system for studying
    and identifying conserved regulators of BH3-only proteins. In C. elegans, the
    BH3-only protein egl-1 is expressed during development to cell-autonomously trigger
    most developmental cell deaths. Here we provide evidence that egl-1 is also transcribed
    after development in the sensory neuron pair URX without inducing apoptosis. We
    used genetic screening and epistasis analysis to determine that its transcription
    is regulated in URX by neuronal activity and/or in parallel by orthologs of Protein
    Kinase G and the Salt-Inducible Kinase family. Because several BH3-only family
    proteins are also expressed in the adult nervous system of mammals, we suggest
    that studying egl-1 expression in URX may shed light on mechanisms that regulate
    conserved family members in higher organisms.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Jesse
      foaf_name: Cohn, Jesse
      foaf_surname: Cohn
  - foaf_Person:
      foaf_givenName: Vivek
      foaf_name: Dwivedi, Vivek
      foaf_surname: Dwivedi
  - foaf_Person:
      foaf_givenName: Giulio
      foaf_name: Valperga, Giulio
      foaf_surname: Valperga
  - foaf_Person:
      foaf_givenName: Nicole
      foaf_name: Zarate, Nicole
      foaf_surname: Zarate
  - foaf_Person:
      foaf_givenName: Mario
      foaf_name: de Bono, Mario
      foaf_surname: de Bono
      foaf_workInfoHomepage: http://www.librecat.org/personId=4E3FF80E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8347-0443
  - foaf_Person:
      foaf_givenName: H. Robert
      foaf_name: Horvitz, H. Robert
      foaf_surname: Horvitz
  - foaf_Person:
      foaf_givenName: Jonathan T.
      foaf_name: Pierce, Jonathan T.
      foaf_surname: Pierce
  bibo_doi: 10.1534/g3.119.400654
  bibo_issue: '11'
  bibo_volume: 9
  dct_date: 2019^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/2160-1836
  dct_language: eng
  dct_publisher: Genetics Society of America@
  dct_title: Activity-dependent regulation of the proapoptotic BH3-only gene egl-1
    in a living neuron pair in Caenorhabditis elegans@
  fabio_hasPubmedId: '31519744'
...