---
_id: '7632'
abstract:
- lang: eng
text: The posterior parietal cortex (PPC) and frontal motor areas comprise a cortical
network supporting goal-directed behaviour, with functions including sensorimotor
transformations and decision making. In primates, this network links performed
and observed actions via mirror neurons, which fire both when individuals perform
an action and when they observe the same action performed by a conspecific. Mirror
neurons are believed to be important for social learning, but it is not known
whether mirror-like neurons occur in similar networks in other social species,
such as rodents, or if they can be measured in such models using paradigms where
observers passively view a demonstrator. Therefore, we imaged Ca2+ responses in
PPC and secondary motor cortex (M2) while mice performed and observed pellet-reaching
and wheel-running tasks, and found that cell populations in both areas robustly
encoded several naturalistic behaviours. However, neural responses to the same
set of observed actions were absent, although we verified that observer mice were
attentive to performers and that PPC neurons responded reliably to visual cues.
Statistical modelling also indicated that executed actions outperformed observed
actions in predicting neural responses. These results raise the possibility that
sensorimotor action recognition in rodents could take place outside of the parieto-frontal
circuit, and underscore that detecting socially-driven neural coding depends critically
on the species and behavioural paradigm used.
article_number: '5559'
article_processing_charge: No
article_type: original
author:
- first_name: Tuce
full_name: Tombaz, Tuce
last_name: Tombaz
- first_name: Benjamin A.
full_name: Dunn, Benjamin A.
last_name: Dunn
- first_name: Karoline
full_name: Hovde, Karoline
last_name: Hovde
- first_name: Ryan J
full_name: Cubero, Ryan J
id: 850B2E12-9CD4-11E9-837F-E719E6697425
last_name: Cubero
orcid: 0000-0003-0002-1867
- first_name: Bartul
full_name: Mimica, Bartul
last_name: Mimica
- first_name: Pranav
full_name: Mamidanna, Pranav
last_name: Mamidanna
- first_name: Yasser
full_name: Roudi, Yasser
last_name: Roudi
- first_name: Jonathan R.
full_name: Whitlock, Jonathan R.
last_name: Whitlock
citation:
ama: Tombaz T, Dunn BA, Hovde K, et al. Action representation in the mouse parieto-frontal
network. Scientific reports. 2020;10(1). doi:10.1038/s41598-020-62089-6
apa: Tombaz, T., Dunn, B. A., Hovde, K., Cubero, R. J., Mimica, B., Mamidanna, P.,
… Whitlock, J. R. (2020). Action representation in the mouse parieto-frontal network.
Scientific Reports. Springer Nature. https://doi.org/10.1038/s41598-020-62089-6
chicago: Tombaz, Tuce, Benjamin A. Dunn, Karoline Hovde, Ryan J Cubero, Bartul Mimica,
Pranav Mamidanna, Yasser Roudi, and Jonathan R. Whitlock. “Action Representation
in the Mouse Parieto-Frontal Network.” Scientific Reports. Springer Nature,
2020. https://doi.org/10.1038/s41598-020-62089-6.
ieee: T. Tombaz et al., “Action representation in the mouse parieto-frontal
network,” Scientific reports, vol. 10, no. 1. Springer Nature, 2020.
ista: Tombaz T, Dunn BA, Hovde K, Cubero RJ, Mimica B, Mamidanna P, Roudi Y, Whitlock
JR. 2020. Action representation in the mouse parieto-frontal network. Scientific
reports. 10(1), 5559.
mla: Tombaz, Tuce, et al. “Action Representation in the Mouse Parieto-Frontal Network.”
Scientific Reports, vol. 10, no. 1, 5559, Springer Nature, 2020, doi:10.1038/s41598-020-62089-6.
short: T. Tombaz, B.A. Dunn, K. Hovde, R.J. Cubero, B. Mimica, P. Mamidanna, Y.
Roudi, J.R. Whitlock, Scientific Reports 10 (2020).
date_created: 2020-04-05T22:00:47Z
date_published: 2020-03-27T00:00:00Z
date_updated: 2023-08-18T10:25:13Z
day: '27'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1038/s41598-020-62089-6
external_id:
isi:
- '000560406800007'
file:
- access_level: open_access
checksum: e6cfaaaf7986532132934400038b824a
content_type: application/pdf
creator: dernst
date_created: 2020-04-06T10:44:23Z
date_updated: 2020-07-14T12:48:01Z
file_id: '7644'
file_name: 2020_ScientificReports_Tombaz.pdf
file_size: 2621249
relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Scientific reports
publication_identifier:
eissn:
- '20452322'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Action representation in the mouse parieto-frontal network
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2020'
...