article published yes Andrej Hurny author 4DC4AF46-F248-11E8-B48F-1D18A9856A870000-0003-3638-1426 Candela Cuesta author 33A3C818-F248-11E8-B48F-1D18A9856A870000-0003-1923-2410 Nicola Cavallari author 457160E6-F248-11E8-B48F-1D18A9856A87 Krisztina Ötvös author 29B901B0-F248-11E8-B48F-1D18A9856A870000-0002-5503-4983 Jerome Duclercq author Ladislav Dokládal author Juan C Montesinos López author 310A8E3E-F248-11E8-B48F-1D18A9856A870000-0001-9179-6099 Marçal Gallemi author 460C6802-F248-11E8-B48F-1D18A9856A870000-0003-4675-6893 Hana Semeradova author 42FE702E-F248-11E8-B48F-1D18A9856A87 Thomas Rauter author A0385D1A-9376-11EA-A47D-9862C5E3AB22 Irene Stenzel author Geert Persiau author Freia Benade author Rishikesh Bhalearo author Eva Sýkorová author András Gorzsás author Julien Sechet author Gregory Mouille author Ingo Heilmann author Geert De Jaeger author Jutta Ludwig-Müller author Eva Benková author 38F4F166-F248-11E8-B48F-1D18A9856A870000-0002-8510-9739 EvBe department Hormone cross-talk drives nutrient dependent plant development project International IST Postdoc Fellowship Programme project Plants as non-mobile organisms constantly integrate varying environmental signals to flexibly adapt their growth and development. Local fluctuations in water and nutrient availability, sudden changes in temperature or other abiotic and biotic stresses can trigger changes in the growth of plant organs. Multiple mutually interconnected hormonal signaling cascades act as essential endogenous translators of these exogenous signals in the adaptive responses of plants. Although the molecular backbones of hormone transduction pathways have been identified, the mechanisms underlying their interactions are largely unknown. Here, using genome wide transcriptome profiling we identify an auxin and cytokinin cross-talk component; SYNERGISTIC ON AUXIN AND CYTOKININ 1 (SYAC1), whose expression in roots is strictly dependent on both of these hormonal pathways. We show that SYAC1 is a regulator of secretory pathway, whose enhanced activity interferes with deposition of cell wall components and can fine-tune organ growth and sensitivity to soil pathogens. https://research-explorer.ista.ac.at/download/7805/8614/2020_NatureComm_Hurny.pdf application/pdfno Springer Nature2020 eng 2041-1723 32358503 00053142590001210.1038/s41467-020-15895-5 11 Hurny A, Cuesta C, Cavallari N, et al. Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. <i>Nature Communications</i>. 2020;11. doi:<a href="https://doi.org/10.1038/s41467-020-15895-5">10.1038/s41467-020-15895-5</a> A. Hurny, C. Cuesta, N. Cavallari, K. Ötvös, J. Duclercq, L. Dokládal, J.C. Montesinos López, M. Gallemi, H. Semerádová, T. Rauter, I. Stenzel, G. Persiau, F. Benade, R. Bhalearo, E. Sýkorová, A. Gorzsás, J. Sechet, G. Mouille, I. Heilmann, G. De Jaeger, J. Ludwig-Müller, E. Benková, Nature Communications 11 (2020). Hurny A, Cuesta C, Cavallari N, Ötvös K, Duclercq J, Dokládal L, Montesinos López JC, Gallemi M, Semerádová H, Rauter T, Stenzel I, Persiau G, Benade F, Bhalearo R, Sýkorová E, Gorzsás A, Sechet J, Mouille G, Heilmann I, De Jaeger G, Ludwig-Müller J, Benková E. 2020. Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. Nature Communications. 11, 2170. A. Hurny <i>et al.</i>, “Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020. Hurny, A., Cuesta, C., Cavallari, N., Ötvös, K., Duclercq, J., Dokládal, L., … Benková, E. (2020). Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-020-15895-5">https://doi.org/10.1038/s41467-020-15895-5</a> Hurny, Andrej, Candela Cuesta, Nicola Cavallari, Krisztina Ötvös, Jerome Duclercq, Ladislav Dokládal, Juan C Montesinos López, et al. “Synergistic on Auxin and Cytokinin 1 Positively Regulates Growth and Attenuates Soil Pathogen Resistance.” <i>Nature Communications</i>. Springer Nature, 2020. <a href="https://doi.org/10.1038/s41467-020-15895-5">https://doi.org/10.1038/s41467-020-15895-5</a>. Hurny, Andrej, et al. “Synergistic on Auxin and Cytokinin 1 Positively Regulates Growth and Attenuates Soil Pathogen Resistance.” <i>Nature Communications</i>, vol. 11, 2170, Springer Nature, 2020, doi:<a href="https://doi.org/10.1038/s41467-020-15895-5">10.1038/s41467-020-15895-5</a>. 78052020-05-10T22:00:48Z2026-04-02T14:32:53Z