---
res:
  bibo_abstract:
  - All vertebrates have a spinal cord with dimensions and shape specific to their
    species. Yet how species‐specific organ size and shape are achieved is a fundamental
    unresolved question in biology. The formation and sculpting of organs begins during
    embryonic development. As it develops, the spinal cord extends in anterior–posterior
    direction in synchrony with the overall growth of the body. The dorsoventral (DV)
    and apicobasal lengths of the spinal cord neuroepithelium also change, while at
    the same time a characteristic pattern of neural progenitor subtypes along the
    DV axis is established and elaborated. At the basis of these changes in tissue
    size and shape are biophysical determinants, such as the change in cell number,
    cell size and shape, and anisotropic tissue growth. These processes are controlled
    by global tissue‐scale regulators, such as morphogen signaling gradients as well
    as mechanical forces. Current challenges in the field are to uncover how these
    tissue‐scale regulatory mechanisms are translated to the cellular and molecular
    level, and how regulation of distinct cellular processes gives rise to an overall
    defined size. Addressing these questions will help not only to achieve a better
    understanding of how size is controlled, but also of how tissue size is coordinated
    with the specification of pattern.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Katarzyna
      foaf_name: Kuzmicz-Kowalska, Katarzyna
      foaf_surname: Kuzmicz-Kowalska
      foaf_workInfoHomepage: http://www.librecat.org/personId=4CED352A-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Anna
      foaf_name: Kicheva, Anna
      foaf_surname: Kicheva
      foaf_workInfoHomepage: http://www.librecat.org/personId=3959A2A0-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-4509-4998
  bibo_doi: 10.1002/wdev.383
  dct_date: 2021^xs_gYear
  dct_identifier:
  - UT:000531419400001
  dct_isPartOf:
  - http://id.crossref.org/issn/1759-7684
  - http://id.crossref.org/issn/1759-7692
  dct_language: eng
  dct_publisher: Wiley@
  dct_title: Regulation of size and scale in vertebrate spinal cord development@
  fabio_hasPubmedId: '32391980'
...