---
_id: '8028'
abstract:
- lang: eng
  text: 'Transmission of signals within the brain is essential for cognitive function,
    but it is not clear how neural circuits support reliable and accurate signal propagation
    over a sufficiently large dynamic range. Two modes of propagation have been studied:
    synfire chains, in which synchronous activity travels through feedforward layers
    of a neuronal network, and the propagation of fluctuations in firing rate across
    these layers. In both cases, a sufficient amount of noise, which was added to
    previous models from an external source, had to be included to support stable
    propagation. Sparse, randomly connected networks of spiking model neurons can
    generate chaotic patterns of activity. We investigate whether this activity, which
    is a more realistic noise source, is sufficient to allow for signal transmission.
    We find that, for rate-coded signals but not for synfire chains, such networks
    support robust and accurate signal reproduction through up to six layers if appropriate
    adjustments are made in synaptic strengths. We investigate the factors affecting
    transmission and show that multiple signals can propagate simultaneously along
    different pathways. Using this feature, we show how different types of logic gates
    can arise within the architecture of the random network through the strengthening
    of specific synapses.'
article_processing_charge: No
article_type: original
author:
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
- first_name: L. F.
  full_name: Abbott, L. F.
  last_name: Abbott
citation:
  ama: Vogels TP, Abbott LF. Signal propagation and logic gating in networks of integrate-and-fire
    neurons. <i>Journal of Neuroscience</i>. 2005;25(46):10786-10795. doi:<a href="https://doi.org/10.1523/jneurosci.3508-05.2005">10.1523/jneurosci.3508-05.2005</a>
  apa: Vogels, T. P., &#38; Abbott, L. F. (2005). Signal propagation and logic gating
    in networks of integrate-and-fire neurons. <i>Journal of Neuroscience</i>. Society
    for Neuroscience. <a href="https://doi.org/10.1523/jneurosci.3508-05.2005">https://doi.org/10.1523/jneurosci.3508-05.2005</a>
  chicago: Vogels, Tim P, and L. F. Abbott. “Signal Propagation and Logic Gating in
    Networks of Integrate-and-Fire Neurons.” <i>Journal of Neuroscience</i>. Society
    for Neuroscience, 2005. <a href="https://doi.org/10.1523/jneurosci.3508-05.2005">https://doi.org/10.1523/jneurosci.3508-05.2005</a>.
  ieee: T. P. Vogels and L. F. Abbott, “Signal propagation and logic gating in networks
    of integrate-and-fire neurons,” <i>Journal of Neuroscience</i>, vol. 25, no. 46.
    Society for Neuroscience, pp. 10786–10795, 2005.
  ista: Vogels TP, Abbott LF. 2005. Signal propagation and logic gating in networks
    of integrate-and-fire neurons. Journal of Neuroscience. 25(46), 10786–10795.
  mla: Vogels, Tim P., and L. F. Abbott. “Signal Propagation and Logic Gating in Networks
    of Integrate-and-Fire Neurons.” <i>Journal of Neuroscience</i>, vol. 25, no. 46,
    Society for Neuroscience, 2005, pp. 10786–95, doi:<a href="https://doi.org/10.1523/jneurosci.3508-05.2005">10.1523/jneurosci.3508-05.2005</a>.
  short: T.P. Vogels, L.F. Abbott, Journal of Neuroscience 25 (2005) 10786–10795.
date_created: 2020-06-25T13:12:33Z
date_published: 2005-11-16T00:00:00Z
date_updated: 2021-01-12T08:16:37Z
day: '16'
doi: 10.1523/jneurosci.3508-05.2005
extern: '1'
external_id:
  pmid:
  - '16291952'
intvolume: '        25'
issue: '46'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725859/
month: '11'
oa: 1
oa_version: Published Version
page: 10786-10795
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
  issn:
  - 0270-6474
  - 1529-2401
publication_status: published
publisher: Society for Neuroscience
quality_controlled: '1'
status: public
title: Signal propagation and logic gating in networks of integrate-and-fire neurons
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 25
year: '2005'
...