---
res:
  bibo_abstract:
  - Transverse relaxation rate measurements in magic-angle spinning solid-state nuclear
    magnetic resonance provide information about molecular motions occurring on nanosecond-to-millisecond
    (ns–ms) time scales. The measurement of heteronuclear (13C, 15N) relaxation rate
    constants in the presence of a spin-lock radiofrequency field (R1ρ relaxation)
    provides access to such motions, and an increasing number of studies involving
    R1ρ relaxation in proteins have been reported. However, two factors that influence
    the observed relaxation rate constants have so far been neglected, namely, (1)
    the role of CSA/dipolar cross-correlated relaxation (CCR) and (2) the impact of
    fast proton spin flips (i.e., proton spin diffusion and relaxation). We show that
    CSA/D CCR in R1ρ experiments is measurable and that the CCR rate constant depends
    on ns–ms motions; it can thus provide insight into dynamics. We find that proton
    spin diffusion attenuates this CCR due to its decoupling effect on the doublet
    components. For measurements of dynamics, the use of R1ρ rate constants has practical
    advantages over the use of CCR rates, and this article reveals factors that have
    so far been disregarded and which are important for accurate measurements and
    interpretation.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Vilius
      foaf_name: Kurauskas, Vilius
      foaf_surname: Kurauskas
  - foaf_Person:
      foaf_givenName: Emmanuelle
      foaf_name: Weber, Emmanuelle
      foaf_surname: Weber
  - foaf_Person:
      foaf_givenName: Audrey
      foaf_name: Hessel, Audrey
      foaf_surname: Hessel
  - foaf_Person:
      foaf_givenName: Isabel
      foaf_name: Ayala, Isabel
      foaf_surname: Ayala
  - foaf_Person:
      foaf_givenName: Dominique
      foaf_name: Marion, Dominique
      foaf_surname: Marion
  - foaf_Person:
      foaf_givenName: Paul
      foaf_name: Schanda, Paul
      foaf_surname: Schanda
      foaf_workInfoHomepage: http://www.librecat.org/personId=7B541462-FAF6-11E9-A490-E8DFE5697425
    orcid: 0000-0002-9350-7606
  bibo_doi: 10.1021/acs.jpcb.6b06129
  bibo_issue: '34'
  bibo_volume: 120
  dct_date: 2016^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1520-6106
  - http://id.crossref.org/issn/1520-5207
  dct_language: eng
  dct_publisher: American Chemical Society@
  dct_subject:
  - Physical and Theoretical Chemistry
  - Materials Chemistry
  - Surfaces
  - Coatings and Films
  dct_title: 'Cross-correlated relaxation of dipolar coupling and chemical-shift anisotropy
    in magic-angle spinning R1ρ NMR measurements: Application to protein backbone
    dynamics measurements@'
...