Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds Schanda, Paul ; https://orcid.org/0000-0002-9350-7606 Brutscher, Bernhard Colloid and Surface Chemistry Biochemistry General Chemistry Catalysis We demonstrate for different protein samples that 2D 1H−15N correlation NMR spectra can be recorded in a few seconds of acquisition time using a new band-selective optimized flip-angle short-transient heteronuclear multiple quantum coherence experiment. This has enabled us to measure fast hydrogen−deuterium exchange rate constants along the backbone of a small globular protein fragment by real-time 2D NMR. American Chemical Society 2005 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_2df8fbb1 https://research-explorer.ista.ac.at/record/8492 Schanda P, Brutscher B. Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds. <i>Journal of the American Chemical Society</i>. 2005;127(22):8014-8015. doi:<a href="https://doi.org/10.1021/ja051306e">10.1021/ja051306e</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1021/ja051306e info:eu-repo/semantics/altIdentifier/issn/0002-7863 info:eu-repo/semantics/altIdentifier/issn/1520-5126 info:eu-repo/semantics/closedAccess