---
res:
  bibo_abstract:
  - 'In mammals, chromatin marks at imprinted genes are asymmetrically inherited to
    control parentally-biased gene expression. This control is thought predominantly
    to involve parent-specific differentially methylated regions (DMR) in genomic
    DNA. However, neither parent-of-origin-specific transcription nor DMRs have been
    comprehensively mapped. We here address this by integrating transcriptomic and
    epigenomic approaches in mouse preimplantation embryos (blastocysts). Transcriptome-analysis
    identified 71 genes expressed with previously unknown parent-of-origin-specific
    expression in blastocysts (nBiX: novel blastocyst-imprinted expression). Uniparental
    expression of nBiX genes disappeared soon after implantation. Micro-whole-genome
    bisulfite sequencing (μWGBS) of individual uniparental blastocysts detected 859
    DMRs. Only 18% of nBiXs were associated with a DMR, whereas 60% were associated
    with parentally-biased H3K27me3. This suggests a major role for Polycomb-mediated
    imprinting in blastocysts. Five nBiX-clusters contained at least one known imprinted
    gene, and five novel clusters contained exclusively nBiX-genes. These data suggest
    a complex program of stage-specific imprinting involving different tiers of regulation.@eng'
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Laura
      foaf_name: Santini, Laura
      foaf_surname: Santini
  - foaf_Person:
      foaf_givenName: Florian
      foaf_name: Halbritter, Florian
      foaf_surname: Halbritter
  - foaf_Person:
      foaf_givenName: Fabian
      foaf_name: Titz-Teixeira, Fabian
      foaf_surname: Titz-Teixeira
  - foaf_Person:
      foaf_givenName: Toru
      foaf_name: Suzuki, Toru
      foaf_surname: Suzuki
  - foaf_Person:
      foaf_givenName: Maki
      foaf_name: Asami, Maki
      foaf_surname: Asami
  - foaf_Person:
      foaf_givenName: Julia
      foaf_name: Ramesmayer, Julia
      foaf_surname: Ramesmayer
  - foaf_Person:
      foaf_givenName: Xiaoyan
      foaf_name: Ma, Xiaoyan
      foaf_surname: Ma
  - foaf_Person:
      foaf_givenName: Andreas
      foaf_name: Lackner, Andreas
      foaf_surname: Lackner
  - foaf_Person:
      foaf_givenName: Nick
      foaf_name: Warr, Nick
      foaf_surname: Warr
  - foaf_Person:
      foaf_givenName: Florian
      foaf_name: Pauler, Florian
      foaf_surname: Pauler
      foaf_workInfoHomepage: http://www.librecat.org/personId=48EA0138-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-7462-0048
  - foaf_Person:
      foaf_givenName: Simon
      foaf_name: Hippenmeyer, Simon
      foaf_surname: Hippenmeyer
      foaf_workInfoHomepage: http://www.librecat.org/personId=37B36620-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-2279-1061
  - foaf_Person:
      foaf_givenName: Ernest
      foaf_name: Laue, Ernest
      foaf_surname: Laue
  - foaf_Person:
      foaf_givenName: Matthias
      foaf_name: Farlik, Matthias
      foaf_surname: Farlik
  - foaf_Person:
      foaf_givenName: Christoph
      foaf_name: Bock, Christoph
      foaf_surname: Bock
  - foaf_Person:
      foaf_givenName: Andreas
      foaf_name: Beyer, Andreas
      foaf_surname: Beyer
  - foaf_Person:
      foaf_givenName: Anthony C. F.
      foaf_name: Perry, Anthony C. F.
      foaf_surname: Perry
  - foaf_Person:
      foaf_givenName: Martin
      foaf_name: Leeb, Martin
      foaf_surname: Leeb
  bibo_doi: 10.1101/2020.11.03.366948
  dct_date: 2020^xs_gYear
  dct_language: eng
  dct_title: Novel imprints in mouse blastocysts are predominantly DNA methylation
    independent@
  fabio_hasPubmedId: 'PPR234457 '
...