{"extern":1,"title":"The evolution of gene duplications: Classifying and distinguishing between models","publication_status":"published","status":"public","date_published":"2010-02-01T00:00:00Z","date_created":"2018-12-11T11:49:03Z","month":"02","day":"01","publisher":"Nature Publishing Group","year":"2010","type":"journal_article","volume":11,"_id":"891","abstract":[{"text":"Gene duplications and their subsequent divergence play an important part in the evolution of novel gene functions. Several models for the emergence, maintenance and evolution of gene copies have been proposed. However, a clear consensus on how gene duplications are fixed and maintained in genomes is lacking. Here, we present a comprehensive classification of the models that are relevant to all stages of the evolution of gene duplications. Each model predicts a unique combination of evolutionary dynamics and functional properties. Setting out these predictions is an important step towards identifying the main mechanisms that are involved in the evolution of gene duplications.","lang":"eng"}],"publication":"Nature Reviews Genetics","date_updated":"2021-01-12T08:21:19Z","quality_controlled":0,"page":"97 - 108","acknowledgement":"We thank M. Lynch for insightful comments on the manuscript.\n","intvolume":" 11","citation":{"chicago":"Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications: Classifying and Distinguishing between Models.” Nature Reviews Genetics. Nature Publishing Group, 2010. https://doi.org/10.1038/nrg2689.","apa":"Innan, H., & Kondrashov, F. (2010). The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics. Nature Publishing Group. https://doi.org/10.1038/nrg2689","mla":"Innan, Hideki, and Fyodor Kondrashov. “The Evolution of Gene Duplications: Classifying and Distinguishing between Models.” Nature Reviews Genetics, vol. 11, no. 2, Nature Publishing Group, 2010, pp. 97–108, doi:10.1038/nrg2689.","ieee":"H. Innan and F. Kondrashov, “The evolution of gene duplications: Classifying and distinguishing between models,” Nature Reviews Genetics, vol. 11, no. 2. Nature Publishing Group, pp. 97–108, 2010.","ista":"Innan H, Kondrashov F. 2010. The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics. 11(2), 97–108.","ama":"Innan H, Kondrashov F. The evolution of gene duplications: Classifying and distinguishing between models. Nature Reviews Genetics. 2010;11(2):97-108. doi:10.1038/nrg2689","short":"H. Innan, F. Kondrashov, Nature Reviews Genetics 11 (2010) 97–108."},"author":[{"full_name":"Innan, Hideki","last_name":"Innan","first_name":"Hideki"},{"orcid":"0000-0001-8243-4694","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","first_name":"Fyodor","last_name":"Kondrashov","full_name":"Fyodor Kondrashov"}],"publist_id":"6755","doi":"10.1038/nrg2689","issue":"2"}