{"has_accepted_license":"1","file":[{"creator":"dernst","date_updated":"2021-03-02T09:29:56Z","success":1,"file_size":11669407,"access_level":"open_access","content_type":"application/pdf","file_name":"2017_eLife_Gaillochet.pdf","checksum":"51c8968a845df5077643c3e3e139d34f","relation":"main_file","date_created":"2021-03-02T09:29:56Z","file_id":"9214"}],"author":[{"full_name":"Gaillochet, Christophe","last_name":"Gaillochet","first_name":"Christophe"},{"first_name":"Thomas","last_name":"Stiehl","full_name":"Stiehl, Thomas"},{"first_name":"Christian","last_name":"Wenzl","full_name":"Wenzl, Christian"},{"last_name":"Ripoll","full_name":"Ripoll, Juan-José","first_name":"Juan-José"},{"full_name":"Bailey-Steinitz, Lindsay J","last_name":"Bailey-Steinitz","first_name":"Lindsay J"},{"first_name":"Lanxin","full_name":"Li, Lanxin","orcid":"0000-0002-5607-272X","last_name":"Li","id":"367EF8FA-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Anne","full_name":"Pfeiffer, Anne","last_name":"Pfeiffer"},{"full_name":"Miotk, Andrej","last_name":"Miotk","first_name":"Andrej"},{"last_name":"Hakenjos","full_name":"Hakenjos, Jana P","first_name":"Jana P"},{"full_name":"Forner, Joachim","last_name":"Forner","first_name":"Joachim"},{"full_name":"Yanofsky, Martin F","last_name":"Yanofsky","first_name":"Martin F"},{"full_name":"Marciniak-Czochra, Anna","last_name":"Marciniak-Czochra","first_name":"Anna"},{"first_name":"Jan U","full_name":"Lohmann, Jan U","last_name":"Lohmann"}],"article_number":"e30135","_id":"9190","year":"2017","article_type":"original","publication_identifier":{"issn":["2050-084X"]},"ddc":["580"],"oa":1,"volume":6,"date_updated":"2021-03-02T09:33:54Z","doi":"10.7554/elife.30135","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"quality_controlled":"1","day":"23","citation":{"short":"C. Gaillochet, T. Stiehl, C. Wenzl, J.-J. Ripoll, L.J. Bailey-Steinitz, L. Li, A. Pfeiffer, A. Miotk, J.P. Hakenjos, J. Forner, M.F. Yanofsky, A. Marciniak-Czochra, J.U. Lohmann, ELife 6 (2017).","apa":"Gaillochet, C., Stiehl, T., Wenzl, C., Ripoll, J.-J., Bailey-Steinitz, L. J., Li, L., … Lohmann, J. U. (2017). Control of plant cell fate transitions by transcriptional and hormonal signals. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.30135","ama":"Gaillochet C, Stiehl T, Wenzl C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. eLife. 2017;6. doi:10.7554/elife.30135","ieee":"C. Gaillochet et al., “Control of plant cell fate transitions by transcriptional and hormonal signals,” eLife, vol. 6. eLife Sciences Publications, 2017.","chicago":"Gaillochet, Christophe, Thomas Stiehl, Christian Wenzl, Juan-José Ripoll, Lindsay J Bailey-Steinitz, Lanxin Li, Anne Pfeiffer, et al. “Control of Plant Cell Fate Transitions by Transcriptional and Hormonal Signals.” ELife. eLife Sciences Publications, 2017. https://doi.org/10.7554/elife.30135.","ista":"Gaillochet C, Stiehl T, Wenzl C, Ripoll J-J, Bailey-Steinitz LJ, Li L, Pfeiffer A, Miotk A, Hakenjos JP, Forner J, Yanofsky MF, Marciniak-Czochra A, Lohmann JU. 2017. Control of plant cell fate transitions by transcriptional and hormonal signals. eLife. 6, e30135.","mla":"Gaillochet, Christophe, et al. “Control of Plant Cell Fate Transitions by Transcriptional and Hormonal Signals.” ELife, vol. 6, e30135, eLife Sciences Publications, 2017, doi:10.7554/elife.30135."},"abstract":[{"text":"Plant meristems carry pools of continuously active stem cells, whose activity is controlled by developmental and environmental signals. After stem cell division, daughter cells that exit the stem cell domain acquire transit amplifying cell identity before they are incorporated into organs and differentiate. In this study, we used an integrated approach to elucidate the role of HECATE (HEC) genes in regulating developmental trajectories of shoot stem cells in Arabidopsis thaliana. Our work reveals that HEC function stabilizes cell fate in distinct zones of the shoot meristem thereby controlling the spatio-temporal dynamics of stem cell differentiation. Importantly, this activity is concomitant with the local modulation of cellular responses to cytokinin and auxin, two key phytohormones regulating cell behaviour. Mechanistically, we show that HEC factors transcriptionally control and physically interact with MONOPTEROS (MP), a key regulator of auxin signalling, and modulate the autocatalytic stabilization of auxin signalling output.","lang":"eng"}],"article_processing_charge":"No","intvolume":" 6","status":"public","file_date_updated":"2021-03-02T09:29:56Z","publication_status":"published","type":"journal_article","publisher":"eLife Sciences Publications","date_published":"2017-10-23T00:00:00Z","oa_version":"Published Version","date_created":"2021-02-24T17:06:13Z","language":[{"iso":"eng"}],"month":"10","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Control of plant cell fate transitions by transcriptional and hormonal signals","publication":"eLife","external_id":{"pmid":["29058667"]},"pmid":1,"extern":"1","license":"https://creativecommons.org/licenses/by/4.0/"}