---
res:
  bibo_abstract:
  - Like many developing tissues, the vertebrate neural tube is patterned by antiparallel
    morphogen gradients. To understand how these inputs are interpreted, we measured
    morphogen signaling and target gene expression in mouse embryos and chick ex vivo
    assays. From these data, we derived and validated a characteristic decoding map
    that relates morphogen input to the positional identity of neural progenitors.
    Analysis of the observed responses indicates that the underlying interpretation
    strategy minimizes patterning errors in response to the joint input of noisy opposing
    gradients. We reverse-engineered a transcriptional network that provides a mechanistic
    basis for the observed cell fate decisions and accounts for the precision and
    dynamics of pattern formation. Together, our data link opposing gradient dynamics
    in a growing tissue to precise pattern formation.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Marcin P
      foaf_name: Zagórski, Marcin P
      foaf_surname: Zagórski
      foaf_workInfoHomepage: http://www.librecat.org/personId=343DA0DC-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7896-7762
  - foaf_Person:
      foaf_givenName: Yoji
      foaf_name: Tabata, Yoji
      foaf_surname: Tabata
  - foaf_Person:
      foaf_givenName: Nathalie
      foaf_name: Brandenberg, Nathalie
      foaf_surname: Brandenberg
  - foaf_Person:
      foaf_givenName: Matthias
      foaf_name: Lutolf, Matthias
      foaf_surname: Lutolf
  - foaf_Person:
      foaf_givenName: Gasper
      foaf_name: Tkacik, Gasper
      foaf_surname: Tkacik
      foaf_workInfoHomepage: http://www.librecat.org/personId=3D494DCA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-6699-1455
  - foaf_Person:
      foaf_givenName: Tobias
      foaf_name: Bollenbach, Tobias
      foaf_surname: Bollenbach
  - foaf_Person:
      foaf_givenName: James
      foaf_name: Briscoe, James
      foaf_surname: Briscoe
  - foaf_Person:
      foaf_givenName: Anna
      foaf_name: Kicheva, Anna
      foaf_surname: Kicheva
      foaf_workInfoHomepage: http://www.librecat.org/personId=3959A2A0-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-4509-4998
  bibo_doi: 10.1126/science.aam5887
  bibo_issue: '6345'
  bibo_volume: 356
  dct_date: 2017^xs_gYear
  dct_identifier:
  - UT:000404351500036
  dct_isPartOf:
  - http://id.crossref.org/issn/0036-8075
  dct_language: eng
  dct_publisher: American Association for the Advancement of Science@
  dct_title: Decoding of position in the developing neural tube from antiparallel
    morphogen gradients@
  fabio_hasPubmedId: '28663499'
...