---
res:
  bibo_abstract:
  - Proteins of the ARGONAUTE family are important in diverse posttranscriptional
    RNA-mediated gene-silencing systems as well as in transcriptional gene silencing
    in Drosophila and fission yeast and in programmed DNA elimination in Tetrahymena.
    We cloned ARGONAUTE4 (AGO4) from a screen for mutants that suppress silencing
    of the Arabidopsis SUPERMAN(SUP) gene. The ago4-1 mutant reactivated silentSUP
    alleles and decreased CpNpG and asymmetric DNA methylation as well as histone
    H3 lysine-9 methylation. In addition,ago4-1 blocked histone and DNA methylation
    and the accumulation of 25-nucleotide small interfering RNAs (siRNAs) that correspond
    to the retroelement AtSN1. These results suggest that AGO4 and long siRNAs direct
    chromatin modifications, including histone methylation and non-CpG DNA methylation.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Daniel
      foaf_name: Zilberman, Daniel
      foaf_surname: Zilberman
      foaf_workInfoHomepage: http://www.librecat.org/personId=6973db13-dd5f-11ea-814e-b3e5455e9ed1
    orcid: 0000-0002-0123-8649
  - foaf_Person:
      foaf_givenName: ' Xiaofeng'
      foaf_name: Cao,  Xiaofeng
      foaf_surname: Cao
  - foaf_Person:
      foaf_givenName: Steven E.
      foaf_name: Jacobsen, Steven E.
      foaf_surname: Jacobsen
  bibo_doi: 10.1126/science.1079695
  bibo_issue: '5607'
  bibo_volume: 299
  dct_date: 2003^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0036-8075
  - http://id.crossref.org/issn/1095-9203
  dct_language: eng
  dct_publisher: American Association for the Advancement of Science@
  dct_subject:
  - Multidisciplinary
  dct_title: ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone
    methylation@
  fabio_hasPubmedId: '12522258'
...
