---
res:
  bibo_abstract:
  - DNA methylation and histone H1 mediate transcriptional silencing of genes and
    transposable elements, but how they interact is unclear. In plants and animals
    with mosaic genomic methylation, functionally mysterious methylation is also common
    within constitutively active housekeeping genes. Here, we show that H1 is enriched
    in methylated sequences, including genes, of Arabidopsis thaliana, yet this enrichment
    is independent of DNA methylation. Loss of H1 disperses heterochromatin, globally
    alters nucleosome organization, and activates H1-bound genes, but only weakly
    de-represses transposable elements. However, H1 loss strongly activates transposable
    elements hypomethylated through mutation of DNA methyltransferase MET1. Hypomethylation
    of genes also activates antisense transcription, which is modestly enhanced by
    H1 loss. Our results demonstrate that H1 and DNA methylation jointly maintain
    transcriptional homeostasis by silencing transposable elements and aberrant intragenic
    transcripts. Such functionality plausibly explains why DNA methylation, a well-known
    mutagen, has been maintained within coding sequences of crucial plant and animal
    genes.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Jaemyung
      foaf_name: Choi, Jaemyung
      foaf_surname: Choi
  - foaf_Person:
      foaf_givenName: David B.
      foaf_name: Lyons, David B.
      foaf_surname: Lyons
  - foaf_Person:
      foaf_givenName: M. Yvonne
      foaf_name: Kim, M. Yvonne
      foaf_surname: Kim
  - foaf_Person:
      foaf_givenName: Jonathan D.
      foaf_name: Moore, Jonathan D.
      foaf_surname: Moore
  - foaf_Person:
      foaf_givenName: Daniel
      foaf_name: Zilberman, Daniel
      foaf_surname: Zilberman
      foaf_workInfoHomepage: http://www.librecat.org/personId=6973db13-dd5f-11ea-814e-b3e5455e9ed1
    orcid: 0000-0002-0123-8649
  bibo_doi: 10.1016/j.molcel.2019.10.011
  bibo_issue: '2'
  bibo_volume: 77
  dct_date: 2020^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1097-2765
  - http://id.crossref.org/issn/1097-4164
  dct_language: eng
  dct_publisher: Elsevier@
  dct_title: DNA methylation and histone H1 jointly repress transposable elements
    and aberrant intragenic transcripts@
  fabio_hasPubmedId: '31732458'
...