---
res:
  bibo_abstract:
  - Vaccines are thought to be the best available solution for controlling the ongoing
    SARS-CoV-2 pandemic. However, the emergence of vaccine-resistant strains may come
    too rapidly for current vaccine developments to alleviate the health, economic
    and social consequences of the pandemic. To quantify and characterize the risk
    of such a scenario, we created a SIR-derived model with initial stochastic dynamics
    of the vaccine-resistant strain to study the probability of its emergence and
    establishment. Using parameters realistically resembling SARS-CoV-2 transmission,
    we model a wave-like pattern of the pandemic and consider the impact of the rate
    of vaccination and the strength of non-pharmaceutical intervention measures on
    the probability of emergence of a resistant strain. As expected, we found that
    a fast rate of vaccination decreases the probability of emergence of a resistant
    strain. Counterintuitively, when a relaxation of non-pharmaceutical interventions
    happened at a time when most individuals of the population have already been vaccinated
    the probability of emergence of a resistant strain was greatly increased. Consequently,
    we show that a period of transmission reduction close to the end of the vaccination
    campaign can substantially reduce the probability of resistant strain establishment.
    Our results suggest that policymakers and individuals should consider maintaining
    non-pharmaceutical interventions and transmission-reducing behaviours throughout
    the entire vaccination period.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Simon
      foaf_name: Rella, Simon
      foaf_surname: Rella
      foaf_workInfoHomepage: http://www.librecat.org/personId=B4765ACA-AA38-11E9-AC9A-0930E6697425
  - foaf_Person:
      foaf_givenName: Yuliya A.
      foaf_name: Kulikova, Yuliya A.
      foaf_surname: Kulikova
  - foaf_Person:
      foaf_givenName: Emmanouil T.
      foaf_name: Dermitzakis, Emmanouil T.
      foaf_surname: Dermitzakis
  - foaf_Person:
      foaf_givenName: Fyodor
      foaf_name: Kondrashov, Fyodor
      foaf_surname: Kondrashov
      foaf_workInfoHomepage: http://www.librecat.org/personId=44FDEF62-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8243-4694
  bibo_doi: 10.1038/s41598-021-95025-3
  bibo_issue: '1'
  bibo_volume: 11
  dct_date: 2021^xs_gYear
  dct_identifier:
  - UT:000683329100001
  dct_isPartOf:
  - http://id.crossref.org/issn/2045-2322
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Rates of SARS-CoV-2 transmission and vaccination impact the fate of vaccine-resistant
    strains@
  fabio_hasPubmedId: '34330988'
...