Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants Velasquez, Silvia Melina Guo, Xiaoyuan Gallemi, Marçal ; https://orcid.org/0000-0003-4675-6893 Aryal, Bibek Venhuizen, Peter Barbez, Elke Dünser, Kai Alexander Darino, Martin Pӗnčík, Aleš Novák, Ondřej Kalyna, Maria Mouille, Gregory Benková, Eva ; https://orcid.org/0000-0002-8510-9739 Bhalerao, Rishikesh P. Mravec, Jozef Kleine-Vehn, Jürgen auxin growth cell wall xyloglucans hypocotyls gravitropism ddc:575 Size control is a fundamental question in biology, showing incremental complexity in plants, whose cells possess a rigid cell wall. The phytohormone auxin is a vital growth regulator with central importance for differential growth control. Our results indicate that auxin-reliant growth programs affect the molecular complexity of xyloglucans, the major type of cell wall hemicellulose in eudicots. Auxin-dependent induction and repression of growth coincide with reduced and enhanced molecular complexity of xyloglucans, respectively. In agreement with a proposed function in growth control, genetic interference with xyloglucan side decorations distinctly modulates auxin-dependent differential growth rates. Our work proposes that auxin-dependent growth programs have a spatially defined effect on xyloglucan’s molecular structure, which in turn affects cell wall mechanics and specifies differential, gravitropic hypocotyl growth. MDPI 2021 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_2df8fbb1 https://research-explorer.ista.ac.at/record/9986 https://research-explorer.ista.ac.at/download/9986/9988 Velasquez SM, Guo X, Gallemi M, et al. Xyloglucan remodeling defines auxin-dependent differential tissue expansion in plants. <i>International Journal of Molecular Sciences</i>. 2021;22(17). doi:<a href="https://doi.org/10.3390/ijms22179222">10.3390/ijms22179222</a> eng info:eu-repo/semantics/altIdentifier/doi/10.3390/ijms22179222 info:eu-repo/semantics/altIdentifier/issn/1661-6596 info:eu-repo/semantics/altIdentifier/e-issn/1422-0067 info:eu-repo/semantics/altIdentifier/wos/000694347100001 info:eu-repo/semantics/altIdentifier/pmid/34502129 https://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess