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126 Publications


2021 | Journal Article | IST-REx-ID: 8988 | OA
In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1
C.F. Düllberg, A. Auer, N. Canigova, K. Loibl, M. Loose, PNAS 118 (2021).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 9259 | OA
Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 9294 | OA
Engaging the front wheels to drive through fibrous terrain
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
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2021 | Journal Article | IST-REx-ID: 9822 | OA
Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 10834 | OA
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
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2021 | Journal Article | IST-REx-ID: 9094 | OA
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2021 | Journal Article | IST-REx-ID: 9429 | OA
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
[Published Version] View | Files available | DOI | WoS
 

2021 | Thesis | IST-REx-ID: 10307 | OA
Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
[Published Version] View | Files available | DOI
 

2021 | Preprint | IST-REx-ID: 10316 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 

2020 | Journal Article | IST-REx-ID: 7234 | OA
Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes
P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson, M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020) 93–113.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7623 | OA
Modeling adhesion-independent cell migration
G. Jankowiak, D. Peurichard, A. Reversat, C. Schmeiser, M.K. Sixt, Mathematical Models and Methods in Applied Sciences 30 (2020) 513–537.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | arXiv
 

2020 | Journal Article | IST-REx-ID: 7875 | OA
Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7876 | OA
T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
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2020 | Journal Article | IST-REx-ID: 7909 | OA
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
[Published Version] View | Files available | DOI | WoS
 

2020 | Journal Article | IST-REx-ID: 8132
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt MK, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. 2020. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology. 5(49), eabc3979.
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2020 | Journal Article | IST-REx-ID: 8787 | OA
Vascular surveillance by haptotactic blood platelets in inflammation and infection
Nicolai L, Schiefelbein K, Lipsky S, Leunig A, Hoffknecht M, Pekayvaz K, Raude B, Marx C, Ehrlich A, Pircher J, Zhang Z, Saleh I, Marel A-K, Löf A, Petzold T, Lorenz M, Stark K, Pick R, Rosenberger G, Weckbach L, Uhl B, Xia S, Reichel CA, Walzog B, Schulz C, Zheden V, Bender M, Li R, Massberg S, Gärtner FR. 2020. Vascular surveillance by haptotactic blood platelets in inflammation and infection. Nature Communications. 11, 5778.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 8142 | OA
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
J.C. Montesinos López, A. Abuzeineh, A. Kopf, A. Juanes Garcia, K. Ötvös, J. Petrášek, M.K. Sixt, E. Benková, The Embo Journal 39 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2020 | Journal Article | IST-REx-ID: 7885
Cellular locomotion using environmental topography
A. Reversat, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
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2020 | Journal Article | IST-REx-ID: 8190 | OA
Zena Werb (1945-2020): Cell biology in context
M.K. Sixt, A. Huttenlocher, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS
 

2019 | Journal Article | IST-REx-ID: 6824
Patrolling the vascular borders: Platelets in immunity to infection and cancer
F.R. Gärtner, S. Massberg, Nature Reviews Immunology 19 (2019) 747–760.
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2019 | Journal Article | IST-REx-ID: 7009
Mechanisms of 3D cell migration
K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
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2019 | Journal Article | IST-REx-ID: 6988
Platelets in host defense: Experimental and clinical insights
L. Nicolai, F.R. Gärtner, S. Massberg, Trends in Immunology 40 (2019) 922–938.
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2019 | Journal Article | IST-REx-ID: 6979
Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal
A. Kopf, M.K. Sixt, Current Biology 29 (2019) R1091–R1093.
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2019 | Journal Article | IST-REx-ID: 7105 | OA
Persistent and polarized global actin flow is essential for directionality during cell migration
L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E. Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G. Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
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2019 | Journal Article | IST-REx-ID: 7420 | OA
GGA2 and RAB13 promote activity-dependent β1-integrin recycling
P. Sahgal, J.H. Alanko, J. Icha, I. Paatero, H. Hamidi, A. Arjonen, M. Pietilä, A. Rokka, J. Ivaska, Journal of Cell Science 132 (2019).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 7404 | OA
Transient localization of the Arp2/3 complex initiates neuronal dendrite branching in vivo
T. Stürner, A. Tatarnikova, J. Müller, B. Schaffran, H. Cuntz, Y. Zhang, M. Nemethova, S. Bogdan, V. Small, G. Tavosanis, Development 146 (2019).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2019 | Thesis | IST-REx-ID: 6947 | OA
Lymph node mechanics: Deciphering the interplay between stroma contractility, morphology and lymphocyte trafficking
F.P. Assen, Lymph Node Mechanics: Deciphering the Interplay between Stroma Contractility, Morphology and Lymphocyte Trafficking, Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 

2019 | Thesis | IST-REx-ID: 6891 | OA
The implication of cytoskeletal dynamics on leukocyte migration
A. Kopf, The Implication of Cytoskeletal Dynamics on Leukocyte Migration, Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 

2019 | Journal Article | IST-REx-ID: 6328 | OA
Nuclear positioning facilitates amoeboid migration along the path of least resistance
J. Renkawitz, A. Kopf, J.A. Stopp, I. de Vries, M.K. Driscoll, J. Merrin, R. Hauschild, E.S. Welf, G. Danuser, R. Fiolka, M.K. Sixt, Nature 568 (2019) 546–550.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 

2019 | Journal Article | IST-REx-ID: 6877
The neural crest pitches in to remove apoptotic debris
A. Kopf, M.K. Sixt, Cell 179 (2019) 51–53.
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2018 | Journal Article | IST-REx-ID: 6354 | OA
Platelet migration and bacterial trapping assay under flow
S. Fan, M. Lorenz, S. Massberg, F.R. Gärtner, Bio-Protocol 8 (2018).
[Published Version] View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 318 | OA
A fat lot of good for wound healing
A.M. Casano, M.K. Sixt, Developmental Cell 44 (2018) 405–406.
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2018 | Journal Article | IST-REx-ID: 308 | OA
Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration
A. Ratheesh, J. Bicher, M. Smutny, J. Veselá, E. Papusheva, G. Krens, W. Kaufmann, A. György, A.M. Casano, D.E. Siekhaus, Developmental Cell 45 (2018) 331–346.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 437 | OA
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. de Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 5672 | OA
IgM's exit route
A. Reversat, M.K. Sixt, Journal of Experimental Medicine 215 (2018) 2959–2961.
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 275 | OA
Lymphatic exosomes promote dendritic cell migration along guidance cues
M. Brown, L. Johnson, D. Leone, P. Májek, K. Vaahtomeri, D. Senfter, N. Bukosza, H. Schachner, G. Asfour, B. Langer, R. Hauschild, K. Parapatics, Y. Hong, K. Bennett, R. Kain, M. Detmar, M.K. Sixt, D. Jackson, D. Kerjaschki, Journal of Cell Biology 217 (2018) 2205–2221.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 5858 | OA
Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data
S. Hross, F.J. Theis, M.K. Sixt, J. Hasenauer, Journal of the Royal Society Interface 15 (2018).
[Published Version] View | Files available | DOI | WoS
 

2018 | Book Chapter | IST-REx-ID: 153
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
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2018 | Journal Article | IST-REx-ID: 276 | OA
Nano-scale microfluidics to study 3D chemotaxis at the single cell level
C. Frick, P. Dettinger, J. Renkawitz, A. Jauch, C. Berger, M. Recher, T. Schroeder, M. Mehling, PLoS One 13 (2018).
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 5861 | OA
The cell sets the tone
J.H. Alanko, M.K. Sixt, ELife 7 (2018).
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 5984 | OA
Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 5992 | OA
On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility
S. Dolati, F. Kage, J. Mueller, M. Müsken, M. Kirchner, G. Dittmar, M.K. Sixt, K. Rottner, M. Falcke, Molecular Biology of the Cell 29 (2018) 2674–2686.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2018 | Journal Article | IST-REx-ID: 6497 | OA
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+T cells
F. Moalli, X. Ficht, P. Germann, M. Vladymyrov, B. Stolp, I. de Vries, R. Lyck, J. Balmer, A. Fiocchi, M. Kreutzfeldt, D. Merkler, M. Iannacone, A. Ariga, M.H. Stoffel, J. Sharpe, M. Bähler, M.K. Sixt, A. Diz-Muñoz, J.V. Stein, The Journal of Experimental Medicine 2015 (2018) 1869–1890.
[Published Version] View | Files available | DOI | WoS
 

2018 | Journal Article | IST-REx-ID: 402 | OA
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2018 | Thesis | IST-REx-ID: 323 | OA
Branched actin networks in dendritic cell biology
A.F. Leithner, Branched Actin Networks in Dendritic Cell Biology, Institute of Science and Technology Austria, 2018.
[Published Version] View | Files available | DOI
 

2018 | Journal Article | IST-REx-ID: 15 | OA
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2017 | Journal Article | IST-REx-ID: 569 | OA
Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. Reversat, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 571
Migrating platelets are mechano scavengers that collect and bundle bacteria
Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
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2017 | Journal Article | IST-REx-ID: 659 | OA
FMNL formins boost lamellipodial force generation
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 668 | OA
Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 672 | OA
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
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2017 | Journal Article | IST-REx-ID: 677 | OA
The INO80 complex removes H2A.Z to promote presynaptic filament formation during homologous recombination
C. Lademann, J. Renkawitz, B. Pfander, S. Jentsch, Cell Reports 19 (2017) 1294–1303.
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 694 | OA
A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 

2017 | Journal Article | IST-REx-ID: 1161
Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) R24–R25.
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2017 | Journal Article | IST-REx-ID: 727
Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
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2017 | Research Data | IST-REx-ID: 5567 | OA
Immunological synapse DC-Tcells
A.F. Leithner, (2017).
[Published Version] View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 664
The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
View | Files available | DOI
 

2017 | Journal Article | IST-REx-ID: 679 | OA
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2016 | Journal Article | IST-REx-ID: 1137 | OA
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Salzer E, Çaǧdaş D, Hons M, Mace E, Garncarz W, Petronczki O, Platzer R, Pfajfer L, Bilic I, Ban S, Willmann K, Mukherjee M, Supper V, Hsu H, Banerjee P, Sinha P, Mcclanahan F, Zlabinger G, Pickl W, Gribben J, Stockinger H, Bennett K, Huppa J, Dupré L, Sanal Ö, Jäger U, Sixt MK, Tezcan I, Orange J, Boztug K. 2016. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology. 17(12), 1352–1360.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2016 | Journal Article | IST-REx-ID: 1142 | OA
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger M, Radic Sarikas B, Lardeau C, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth S, Decker T, Bennett K, Kubicek S, Sixt MK, Superti Furga G, Knapp S. 2016. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology. 17(12), 1361–1372.
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2016 | Journal Article | IST-REx-ID: 1150
A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
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2016 | Journal Article | IST-REx-ID: 1154 | OA
A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
[Published Version] View | Files available | DOI
 

2016 | Journal Article | IST-REx-ID: 1201
Formin’ a nuclear protection
J. Renkawitz, M.K. Sixt, Cell 167 (2016) 1448–1449.
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2016 | Journal Article | IST-REx-ID: 1217
Efficient T-cell priming and activation requires signaling through prostaglandin E2 (EP) receptors
V. Sreeramkumar, M. Hons, C. Punzón, J. Stein, D. Sancho, M. Fresno Forcelledo, N. Cuesta, Immunology and Cell Biology 94 (2016) 39–51.
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2016 | Journal Article | IST-REx-ID: 1285
Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
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2016 | Journal Article | IST-REx-ID: 1490 | OA
Intralymphatic CCL21 promotes tissue egress of dendritic cells through afferent lymphatic vessels
E. Russo, A. Teijeira, K. Vaahtomeri, A. Willrodt, J. Bloch, M. Nitschké, L. Santambrogio, D. Kerjaschki, M.K. Sixt, C. Halin, Cell Reports 14 (2016) 1723–1734.
[Published Version] View | Files available | DOI
 

2016 | Journal Article | IST-REx-ID: 1599 | OA
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
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2016 | Journal Article | IST-REx-ID: 1597
Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
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2016 | Thesis | IST-REx-ID: 1129 | OA
Quantitative analysis of haptotactic cell migration
J. Schwarz, Quantitative Analysis of Haptotactic Cell Migration, Institute of Science and Technology Austria, 2016.
[Published Version] View | Files available
 

2016 | Journal Article | IST-REx-ID: 1321 | OA
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
[Submitted Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1530
Impact of the cell division cycle on gene circuits
V. Bierbaum, S. Klumpp, Physical Biology 12 (2015).
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2015 | Journal Article | IST-REx-ID: 1553
Actin flows mediate a universal coupling between cell speed and cell persistence
P. Maiuri, J. Rupprecht, S. Wieser, V. Ruprecht, O. Bénichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.-P.J. Heisenberg, C. Lage Crespo, F. Lautenschlaeger, M. Le Berre, A. Lennon Duménil, M. Raab, H. Thiam, M. Piel, M.K. Sixt, R. Voituriez, Cell 161 (2015) 374–386.
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2015 | Journal Article | IST-REx-ID: 1561
A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors
K. Heger, M. Kober, D. Rieß, C. Drees, I. de Vries, A. Bertossi, A. Roers, M.K. Sixt, M. Schmidt Supprian, European Journal of Immunology 45 (2015) 1614–1620.
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2015 | Journal Article | IST-REx-ID: 1560
The lymph node filter revealed
M. Hons, M.K. Sixt, Nature Immunology 16 (2015) 338–340.
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2015 | Journal Article | IST-REx-ID: 1575 | OA
Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells
M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin, E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt, J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications 6 (2015).
[Published Version] View | Files available | DOI
 

2015 | Journal Article | IST-REx-ID: 1676
Editorial overview: Cell adhesion and migration
M.K. Sixt, E. Raz, Current Opinion in Cell Biology 36 (2015) 4–6.
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2015 | Journal Article | IST-REx-ID: 1687 | OA
Navigating in tissue mazes: Chemoattractant interpretation in complex environments
M. Sarris, M.K. Sixt, Current Opinion in Cell Biology 36 (2015) 93–102.
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2015 | Journal Article | IST-REx-ID: 1686 View | DOI
 

2015 | Journal Article | IST-REx-ID: 477
The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst, E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
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2015 | Journal Article | IST-REx-ID: 1618 | OA
Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites
Veldkamp C, Kiermaier E, Gabel Eissens S, Gillitzer M, Lippner D, Disilvio F, Mueller C, Wantuch P, Chaffee G, Famiglietti M, Zgoba D, Bailey A, Bah Y, Engebretson S, Graupner D, Lackner E, Larosa V, Medeiros T, Olson M, Phillips A, Pyles H, Richard A, Schoeller S, Touzeau B, Williams L, Sixt MK, Peterson F. 2015. Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites. Biochemistry. 54(27), 4163–4166.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2015 | Journal Article | IST-REx-ID: 1537 | OA
Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
V. Ruprecht, S. Wieser, A. Callan Jones, M. Smutny, H. Morita, K. Sako, V. Barone, M. Ritsch Marte, M.K. Sixt, R. Voituriez, C.-P.J. Heisenberg, Cell 160 (2015) 673–685.
[Published Version] View | Files available | DOI
 

2014 | Journal Article | IST-REx-ID: 1877
Physiology: Relax and come in
M.K. Sixt, K. Vaahtomeri, Nature 514 (2014) 441–442.
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2014 | Journal Article | IST-REx-ID: 1910
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2
S. Konradi, N. Yasmin, D. Haslwanter, M. Weber, B. Gesslbauer, M.K. Sixt, H. Strobl, European Journal of Immunology 44 (2014) 553–560.
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2014 | Journal Article | IST-REx-ID: 1925 | OA
A single-molecule approach to explore binding uptake and transport of cancer cell targeting nanotubes
C. Lamprecht, B. Plochberger, V. Ruprecht, S. Wieser, C. Rankl, E. Heister, B. Unterauer, M. Brameshuber, J. Danzberger, P. Lukanov, E. Flahaut, G. Schütz, P. Hinterdorfer, A. Ebner, Nanotechnology 25 (2014).
[Submitted Version] View | Files available | DOI
 

2014 | Journal Article | IST-REx-ID: 2158 | OA
New paradigms in the establishment and maintenance of gradients during directed cell migration
R. Majumdar, M.K. Sixt, C. Parent, Current Opinion in Cell Biology 30 (2014) 33–40.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2014 | Journal Article | IST-REx-ID: 2214 | OA
Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects
L. Stoler Barak, C. Moussion, E. Shezen, M. Hatzav, M.K. Sixt, R. Alon, PLoS One 9 (2014).
[Published Version] View | Files available | DOI
 

2014 | Journal Article | IST-REx-ID: 2215
Mechanisms and principles of homology search during recombination
J. Renkawitz, C. Lademann, S. Jentsch, Nature Reviews Molecular Cell Biology 15 (2014) 369–383.
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2014 | Journal Article | IST-REx-ID: 2242
A miR-155-dependent microRNA hierarchy in dendritic cell maturation and macrophage activation
A. Dueck, A. Eichner, M.K. Sixt, G. Meister, FEBS Letters 588 (2014) 632–640.
View | DOI
 

2013 | Journal Article | IST-REx-ID: 2830
A conduit to amplify innate immunity
C. Moussion, M.K. Sixt, Immunity 38 (2013) 853–854.
View | DOI
 

2013 | Journal Article | IST-REx-ID: 2839 | OA
Interstitial dendritic cell guidance by haptotactic chemokine gradients
M. Weber, R. Hauschild, J. Schwarz, C. Moussion, I. de Vries, D. Legler, S. Luther, M.T. Bollenbach, M.K. Sixt, Science 339 (2013) 328–332.
[Published Version] View | DOI | Download Published Version (ext.)
 

2013 | Journal Article | IST-REx-ID: 522
Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells
E. Fuertbauer, J. Zaujec, P. Uhrin, I. Raab, M. Weber, H. Schachner, M. Bauer, G. Schütz, B. Binder, M.K. Sixt, D. Kerjaschki, H. Stockinger, Immunology Letters 154 (2013) 31–41.
View | DOI
 

2013 | Book Chapter | IST-REx-ID: 10900
Live Cell Imaging of Chemotactic Dendritic Cell Migration in Explanted Mouse Ear Preparations
M. Weber, M.K. Sixt, in:, A. Cardona, E. Ubogu (Eds.), Chemokines, Humana Press, Totowa, NJ, 2013, pp. 215–226.
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2012 | Journal Article | IST-REx-ID: 2946 | OA
MicroRNAs associated with the different human Argonaute proteins
A. Dueck, C. Ziegler, A. Eichner, E. Berezikov, G. Meister, Nucleic Acids Research 40 (2012) 9850–9862.
[Published Version] View | Files available | DOI
 

2012 | Journal Article | IST-REx-ID: 2945
HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes
J. Girard, C. Moussion, R. Förster, Nature Reviews Immunology 12 (2012) 762–773.
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2012 | Journal Article | IST-REx-ID: 3167
NextGen speaks 13
M. Weber, Science 336 (2012) 32–34.
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2012 | Journal Article | IST-REx-ID: 3158 | OA
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
H. Schachtner, A. Li, D. Stevenson, S. Calaminus, S. Thomas, S. Watson, M.K. Sixt, R. Wedlich Söldner, D. Strathdee, L. Machesky, European Journal of Cell Biology 91 (2012) 923–929.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2012 | Journal Article | IST-REx-ID: 506 | OA
Cell migration: Fibroblasts find a new way to get ahead
M.K. Sixt, Journal of Cell Biology 197 (2012) 347–349.
[Published Version] View | Files available | DOI
 

2011 | Journal Article | IST-REx-ID: 3287
What can we learn from single molecule trajectories?
V. Ruprecht, M. Axmann, S. Wieser, G. Schuetz, Current Protein & Peptide Science 12 (2011) 714–724.
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2011 | Journal Article | IST-REx-ID: 3371 | OA
Cells on the move in Philadelphia
M.K. Sixt, C. Parent, Molecular Biology and Evolution 22 (2011) 724.
[Published Version] View | Files available | DOI
 

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