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54 Publications
2021 | Published | Journal Article | IST-REx-ID: 15274 |

Cysteine mutants of the major facilitator superfamily-type transporter CcoA provide insight into copper import
B. Khalfaoui-Hassani, P.I. Trasnea, S. Steimle, H.-G. Koch, F. Daldal, MBio 12 (2021).
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B. Khalfaoui-Hassani, P.I. Trasnea, S. Steimle, H.-G. Koch, F. Daldal, MBio 12 (2021).
2021 | Published | Journal Article | IST-REx-ID: 10310 |

Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster
M.O. Çoruh, A. Frank, H. Tanaka, A. Kawamoto, E. El-Mohsnawy, T. Kato, K. Namba, C. Gerle, M.M. Nowaczyk, G. Kurisu, Communications Biology 4 (2021).
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M.O. Çoruh, A. Frank, H. Tanaka, A. Kawamoto, E. El-Mohsnawy, T. Kato, K. Namba, C. Gerle, M.M. Nowaczyk, G. Kurisu, Communications Biology 4 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9205 |

Cryo-EM grid optimization for membrane proteins
D. Kampjut, J. Steiner, L.A. Sazanov, IScience 24 (2021).
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D. Kampjut, J. Steiner, L.A. Sazanov, IScience 24 (2021).
2021 | Published | Journal Article | IST-REx-ID: 10146
Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV
I. Vercellino, L.A. Sazanov, Nature 598 (2021) 364–367.
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I. Vercellino, L.A. Sazanov, Nature 598 (2021) 364–367.
2021 | Published | Journal Article | IST-REx-ID: 8993 |

Naphthylphthalamic acid associates with and inhibits PIN auxin transporters
L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer, L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, Proceedings of the National Academy of Sciences of the United States of America 118 (2021).
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L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer, L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, Proceedings of the National Academy of Sciences of the United States of America 118 (2021).
2020 | Published | Journal Article | IST-REx-ID: 8318 |

Key role of quinone in the mechanism of respiratory complex I
J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).
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J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).
2020 | Published | Journal Article | IST-REx-ID: 8579 |

Cu homeostasis in bacteria: The ins and outs
A. Andrei, Y. Öztürk, B. Khalfaoui-Hassani, J. Rauch, D. Marckmann, P.I. Trasnea, F. Daldal, H.-G. Koch, Membranes 10 (2020).
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A. Andrei, Y. Öztürk, B. Khalfaoui-Hassani, J. Rauch, D. Marckmann, P.I. Trasnea, F. Daldal, H.-G. Koch, Membranes 10 (2020).
2020 | Published | Journal Article | IST-REx-ID: 8040
Charge transfer and chemo-mechanical coupling in respiratory complex I
Gupta, Chitrak, Charge transfer and chemo-mechanical coupling in respiratory complex I. Journal of the American Chemical Society 142 (20). 2020
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Gupta, Chitrak, Charge transfer and chemo-mechanical coupling in respiratory complex I. Journal of the American Chemical Society 142 (20). 2020
2020 | Research Data Reference | IST-REx-ID: 9326
Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
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C. Gupta, U. Khaniya, C. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
2020 | Research Data Reference | IST-REx-ID: 9713
Supporting information
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
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C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
2020 | Research Data Reference | IST-REx-ID: 9878
Movies
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
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C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).
2020 | Published | Journal Article | IST-REx-ID: 7788 |

NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2
Adjobo-Hermans, Merel J.W., NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics 1861 (8). 2020
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Adjobo-Hermans, Merel J.W., NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics 1861 (8). 2020
2020 | Published | Journal Article | IST-REx-ID: 8581
Cryo-EM structure of the entire mammalian F-type ATP synthase
Pinke, Gergely, Cryo-EM structure of the entire mammalian F-type ATP synthase. Nature Structural and Molecular Biology 27 (11). 2020
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Pinke, Gergely, Cryo-EM structure of the entire mammalian F-type ATP synthase. Nature Structural and Molecular Biology 27 (11). 2020
2020 | Published | Journal Article | IST-REx-ID: 8737 |

The coupling mechanism of mammalian respiratory complex I
D. Kampjut, L.A. Sazanov, Science 370 (2020).
[Submitted Version]
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D. Kampjut, L.A. Sazanov, Science 370 (2020).
2020 | Published | Thesis | IST-REx-ID: 8353 |

Biochemical and structural investigation of the Mrp antiporter, an ancestor of complex I
J. Steiner, Biochemical and Structural Investigation of the Mrp Antiporter, an Ancestor of Complex I, Institute of Science and Technology Austria, 2020.
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J. Steiner, Biochemical and Structural Investigation of the Mrp Antiporter, an Ancestor of Complex I, Institute of Science and Technology Austria, 2020.
2020 | Published | Journal Article | IST-REx-ID: 8284 |

Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
J. Steiner, L.A. Sazanov, ELife 9 (2020).
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J. Steiner, L.A. Sazanov, ELife 9 (2020).
2020 | Published | Thesis | IST-REx-ID: 8340 |

Molecular mechanisms of mitochondrial redox-coupled proton pumping enzymes
D. Kampjut, Molecular Mechanisms of Mitochondrial Redox-Coupled Proton Pumping Enzymes, Institute of Science and Technology Austria, 2020.
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D. Kampjut, Molecular Mechanisms of Mitochondrial Redox-Coupled Proton Pumping Enzymes, Institute of Science and Technology Austria, 2020.
2019 | Published | Journal Article | IST-REx-ID: 6352 |

Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure
A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).
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A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).
2019 | Published | Journal Article | IST-REx-ID: 6859
Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
L. Zhou, L.A. Sazanov, Science 365 (2019).
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L. Zhou, L.A. Sazanov, Science 365 (2019).
2019 | Published | Journal Article | IST-REx-ID: 6919 |

Structural basis of sterol recognition by human hedgehog receptor PTCH1
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).
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C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).