Alexander F Leithner
Sixt Group
14 Publications
2023 | Published | Book Chapter | IST-REx-ID: 13052
Leithner, A. F., Merrin, J., & Sixt, M. K. (2023). En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses. In C. Baldari & M. Dustin (Eds.), The Immune Synapse (Vol. 2654, pp. 137–147). New York, NY: Springer Nature. https://doi.org/10.1007/978-1-0716-3135-5_9
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| DOI
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 11843 |

Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., & Sixt, M. K. (2022). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.78995
[Published Version]
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| Files available
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| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10703 |

Gaertner, Florian, WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues. Developmental Cell 57 (1). 2022
[Published Version]
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2021 | Published | Journal Article | IST-REx-ID: 9094 |

Leithner, A. F., Altenburger, L., Hauschild, R., Assen, F. P., Rottner, K., TEB, S., … Sixt, M. K. (2021). Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse. Journal of Cell Biology. Rockefeller University Press. https://doi.org/10.1083/jcb.202006081
[Published Version]
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| Files available
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| WoS
| PubMed | Europe PMC
2021 | Draft | Preprint | IST-REx-ID: 10316 |

Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., & Sixt, M. K. (n.d.). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. bioRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2021.10.18.464770
[Preprint]
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| Files available
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| Download Preprint (ext.)
2018 | Published | Book Chapter | IST-REx-ID: 153
Renkawitz, Jörg, Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments. Methods in Cell Biology 147. 2018
View
| DOI
| WoS
| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 437 |

Leithner, A. F., Renkawitz, J., de Vries, I., Hauschild, R., Haecker, H., & Sixt, M. K. (2018). Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration. European Journal of Immunology. Wiley-Blackwell. https://doi.org/10.1002/eji.201747358
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Thesis | IST-REx-ID: 323 |

Leithner, A. F. (2018). Branched actin networks in dendritic cell biology. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_998
[Published Version]
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| Files available
| DOI
2018 | Published | Journal Article | IST-REx-ID: 15 |

Hons, M., Kopf, A., Hauschild, R., Leithner, A. F., Gärtner, F. R., Abe, J., … Sixt, M. K. (2018). Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nature Immunology. Nature Publishing Group. https://doi.org/10.1038/s41590-018-0109-z
[Published Version]
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| Download Published Version (ext.)
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| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 402 |

Brown, M., Assen, F. P., Leithner, A. F., Abe, J., Schachner, H., Asfour, G., … Kerjaschki, D. (2018). Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aal3662
[Published Version]
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| Files available
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| Download Published Version (ext.)
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2017 | Research Data | IST-REx-ID: 5567 |

Leithner, A. F. (2017). Immunological synapse DC-Tcells. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:71
[Published Version]
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| Files available
| DOI
2017 | Published | Journal Article | IST-REx-ID: 674
Schwarz, J., Bierbaum, V., Vaahtomeri, K., Hauschild, R., Brown, M., de Vries, I., … Sixt, M. K. (2017). Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2017.04.004
View
| DOI
2017 | Published | Journal Article | IST-REx-ID: 672 |

Vaahtomeri, Kari, Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia. Cell Reports 19 (5). 2017
[Published Version]
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| Files available
| DOI
2016 | Published | Journal Article | IST-REx-ID: 1321 |

Leithner, A. F., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz, J., … Sixt, M. K. (2016). Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology. Nature Publishing Group. https://doi.org/10.1038/ncb3426
[Submitted Version]
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| Files available
| DOI
Grants
14 Publications
2023 | Published | Book Chapter | IST-REx-ID: 13052
Leithner, A. F., Merrin, J., & Sixt, M. K. (2023). En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses. In C. Baldari & M. Dustin (Eds.), The Immune Synapse (Vol. 2654, pp. 137–147). New York, NY: Springer Nature. https://doi.org/10.1007/978-1-0716-3135-5_9
View
| DOI
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 11843 |

Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., & Sixt, M. K. (2022). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. ELife. eLife Sciences Publications. https://doi.org/10.7554/eLife.78995
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10703 |

Gaertner, Florian, WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues. Developmental Cell 57 (1). 2022
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2021 | Published | Journal Article | IST-REx-ID: 9094 |

Leithner, A. F., Altenburger, L., Hauschild, R., Assen, F. P., Rottner, K., TEB, S., … Sixt, M. K. (2021). Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse. Journal of Cell Biology. Rockefeller University Press. https://doi.org/10.1083/jcb.202006081
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Draft | Preprint | IST-REx-ID: 10316 |

Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., & Sixt, M. K. (n.d.). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. bioRxiv. Cold Spring Harbor Laboratory. https://doi.org/10.1101/2021.10.18.464770
[Preprint]
View
| Files available
| DOI
| Download Preprint (ext.)
2018 | Published | Book Chapter | IST-REx-ID: 153
Renkawitz, Jörg, Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments. Methods in Cell Biology 147. 2018
View
| DOI
| WoS
| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 437 |

Leithner, A. F., Renkawitz, J., de Vries, I., Hauschild, R., Haecker, H., & Sixt, M. K. (2018). Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration. European Journal of Immunology. Wiley-Blackwell. https://doi.org/10.1002/eji.201747358
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Thesis | IST-REx-ID: 323 |

Leithner, A. F. (2018). Branched actin networks in dendritic cell biology. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_998
[Published Version]
View
| Files available
| DOI
2018 | Published | Journal Article | IST-REx-ID: 15 |

Hons, M., Kopf, A., Hauschild, R., Leithner, A. F., Gärtner, F. R., Abe, J., … Sixt, M. K. (2018). Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells. Nature Immunology. Nature Publishing Group. https://doi.org/10.1038/s41590-018-0109-z
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 402 |

Brown, M., Assen, F. P., Leithner, A. F., Abe, J., Schachner, H., Asfour, G., … Kerjaschki, D. (2018). Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aal3662
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2017 | Research Data | IST-REx-ID: 5567 |

Leithner, A. F. (2017). Immunological synapse DC-Tcells. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:71
[Published Version]
View
| Files available
| DOI
2017 | Published | Journal Article | IST-REx-ID: 674
Schwarz, J., Bierbaum, V., Vaahtomeri, K., Hauschild, R., Brown, M., de Vries, I., … Sixt, M. K. (2017). Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2017.04.004
View
| DOI
2017 | Published | Journal Article | IST-REx-ID: 672 |

Vaahtomeri, Kari, Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia. Cell Reports 19 (5). 2017
[Published Version]
View
| Files available
| DOI
2016 | Published | Journal Article | IST-REx-ID: 1321 |

Leithner, A. F., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz, J., … Sixt, M. K. (2016). Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology. Nature Publishing Group. https://doi.org/10.1038/ncb3426
[Submitted Version]
View
| Files available
| DOI