Molecular Drug Targets
Project Period: 2015-03-01 – 2018-08-31
Funder:
Austrian Science Fund
Acronym
MolTag
Principal Investigator
Department(s)
Grant Number
W1232-B24
Funder
Austrian Science Fund
Funder Schema
FWF-DK
Funder Registry
7 Publications
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 19725 |

A F420-dependent single domain chemogenetic tool for protein de-dimerization
J. Antoney, S. Kainrath, J.G. Dubowsky, F.H. Ahmed, S.W. Kang, E.R.R. Mackie, G. Bracho Granado, T.P. Soares Da Costa, C.J. Jackson, H.L. Janovjak, Journal of Molecular Biology 437 (2025).
[Published Version]
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J. Antoney, S. Kainrath, J.G. Dubowsky, F.H. Ahmed, S.W. Kang, E.R.R. Mackie, G. Bracho Granado, T.P. Soares Da Costa, C.J. Jackson, H.L. Janovjak, Journal of Molecular Biology 437 (2025).
2018 | Published | Journal Article | IST-REx-ID: 5984 |

Optical functionalization of human class A orphan G-protein-coupled receptors
M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
[Published Version]
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M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld, J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
2017 | Published | Journal Article | IST-REx-ID: 538 |

Grünlicht-induzierte Rezeptorinaktivierung durch Cobalamin-bindende Domänen
S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
[Published Version]
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S. Kainrath, M. Stadler, E. Gschaider-Reichhart, M. Distel, H.L. Janovjak, Angewandte Chemie 129 (2017) 4679–4682.
2017 | Published | Journal Article | IST-REx-ID: 1026
Optogenetic methods in drug screening: Technologies and applications
V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
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V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
2016 | Published | Journal Article | IST-REx-ID: 1441 |

A phytochrome sensory domain permits receptor activation by red light
E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L. Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
[Submitted Version]
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E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L. Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
2016 | Published | Journal Article | IST-REx-ID: 1440
Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain
H.L. Janovjak, Structure 24 (2016) 213–215.
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H.L. Janovjak, Structure 24 (2016) 213–215.
2015 | Published | Journal Article | IST-REx-ID: 1678 |

Light-assisted small-molecule screening against protein kinases
Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
[Submitted Version]
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Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.