In situ real-time imaging of neurotransmitter signaling using designer optical sensors
Project Period: 2012-08-01 – 2016-01-31
Funder:
Human Frontier Science Program
Principal Investigator
Department(s)
Grant Number
RGY0084/2012
Funder
Human Frontier Science Program
Funder Schema
HFSP-YIG
Funder Registry
8 Publications
2018 | Published | Journal Article | IST-REx-ID: 137 | 
Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS
W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez-Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
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W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I. Sanchez-Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak, C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
2017 | Published | Journal Article | IST-REx-ID: 1026
Optogenetic methods in drug screening: Technologies and applications
V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
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V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.
2017 | Published | Book Chapter | IST-REx-ID: 957
Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors
Clifton, Ben, Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors. Synthetic Protein Switches 1596. 2017
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Clifton, Ben, Ancestral protein reconstruction and circular permutation for improving the stability and dynamic range of FRET sensors. Synthetic Protein Switches 1596. 2017
2016 | Published | Journal Article | IST-REx-ID: 1440
Light at the end of the protein: Crystal structure of a C-terminal light-sensing domain
H.L. Janovjak, Structure 24 (2016) 213–215.
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H.L. Janovjak, Structure 24 (2016) 213–215.
2015 | Published | Journal Article | IST-REx-ID: 1611 |
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction
J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
[Submitted Version]
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J. Whitfield, W. Zhang, M. Herde, B. Clifton, J. Radziejewski, H.L. Janovjak, C. Henneberger, C. Jackson, Protein Science 24 (2015) 1412–1422.
2015 | Published | Journal Article | IST-REx-ID: 1867
Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence detection
J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
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J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis 36 (2015) 518–525.
2015 | Published | Journal Article | IST-REx-ID: 1678 |
Light-assisted small-molecule screening against protein kinases
Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
[Submitted Version]
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Á. Inglés Prieto, E. Gschaider-Reichhart, M. Muellner, M. Nowak, S. Nijman, M. Grusch, H.L. Janovjak, Nature Chemical Biology 11 (2015) 952–954.
2013 | Published | Journal Article | IST-REx-ID: 2857 |
Optical control of ligand-gated ion channels
S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998 (2013) 417–435.
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S. Szobota, C. Mckenzie, H.L. Janovjak, Methods in Molecular Biology 998 (2013) 417–435.