Biophysically realistic genotype-phenotype maps for regulatory networks

Project Period: 2018-09-01 – 2020-08-31
Externally Funded
Principal Investigator
Rok Grah
Department(s)
Guet Group
Funding Organisation
OEAW

4 Publications

2020 | Journal Article | IST-REx-ID: 9000 | OA
Nonequilibrium models of optimal enhancer function
R. Grah, B. Zoller, G. Tkačik, PNAS 117 (2020) 31614–31622.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2020 | Thesis | IST-REx-ID: 8155 | OA
Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, Institute of Science and Technology Austria, 2020.
[Published Version] View | Files available | DOI
 
2020 | Preprint | IST-REx-ID: 7675 | OA
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2020 | Journal Article | IST-REx-ID: 7652 | OA
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
[Submitted Version] View | Files available | DOI | WoS