Geometric control and modeling of genome reprogramming
Uhler C, Shivashankar GV. 2016. Geometric control and modeling of genome reprogramming. BioArchitecture. 6(4), 76–84.
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Journal Article
| Published
| English
Author
Uhler, CarolineISTA 
;
Shivashankar, G V
;
Shivashankar, G VAbstract
Cell geometry is tightly coupled to gene expression patterns within the tissue microenvironment. This perspective synthesizes evidence that the 3D organization of chromosomes is a critical intermediate for geometric control of genomic programs. Using a combination of experiments and modeling we outline approaches to decipher the mechano-genomic code that governs cellular homeostasis and reprogramming.
Publishing Year
Date Published
2016-07-27
Journal Title
BioArchitecture
Publisher
Taylor & Francis
Volume
6
Issue
4
Page
76 - 84
IST-REx-ID
Cite this
Uhler C, Shivashankar GV. Geometric control and modeling of genome reprogramming. BioArchitecture. 2016;6(4):76-84. doi:10.1080/19490992.2016.1201620
Uhler, C., & Shivashankar, G. V. (2016). Geometric control and modeling of genome reprogramming. BioArchitecture. Taylor & Francis. https://doi.org/10.1080/19490992.2016.1201620
Uhler, Caroline, and G V Shivashankar. “Geometric Control and Modeling of Genome Reprogramming.” BioArchitecture. Taylor & Francis, 2016. https://doi.org/10.1080/19490992.2016.1201620.
C. Uhler and G. V. Shivashankar, “Geometric control and modeling of genome reprogramming,” BioArchitecture, vol. 6, no. 4. Taylor & Francis, pp. 76–84, 2016.
Uhler C, Shivashankar GV. 2016. Geometric control and modeling of genome reprogramming. BioArchitecture. 6(4), 76–84.
Uhler, Caroline, and G. V. Shivashankar. “Geometric Control and Modeling of Genome Reprogramming.” BioArchitecture, vol. 6, no. 4, Taylor & Francis, 2016, pp. 76–84, doi:10.1080/19490992.2016.1201620.
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