Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats
Kumar GS, Pieber B, Reddy KR, Kappe CO. 2012. Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats. Chemistry - A European Journal. 18(20), 6124–6128.
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Journal Article
| Published
| English
Scopus indexed
Author
Kumar, G. Sathish;
Pieber, BartholomäusISTA 
;
Reddy, K. Rajender;
Kappe, C. Oliver
;
Reddy, K. Rajender;
Kappe, C. OliverAbstract
Peroxides and ethers in flow: 2-Carbonyl-substituted phenols and β-ketoesters react safely with ethers in a microreactor environment using a copper catalyst and an organic peroxide (TBHP). This protocol results in unsymmetrical acetal scaffolds not easily available otherwise (see scheme).
Publishing Year
Date Published
2012-05-14
Journal Title
Chemistry - A European Journal
Volume
18
Issue
20
Page
6124-6128
ISSN
eISSN
IST-REx-ID
Cite this
Kumar GS, Pieber B, Reddy KR, Kappe CO. Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats. Chemistry - A European Journal. 2012;18(20):6124-6128. doi:10.1002/chem.201200815
Kumar, G. S., Pieber, B., Reddy, K. R., & Kappe, C. O. (2012). Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats. Chemistry - A European Journal. Wiley. https://doi.org/10.1002/chem.201200815
Kumar, G. Sathish, Bartholomäus Pieber, K. Rajender Reddy, and C. Oliver Kappe. “Copper-Catalyzed Formation of C-O Bonds by Direct α-C-H Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous-Flow Formats.” Chemistry - A European Journal. Wiley, 2012. https://doi.org/10.1002/chem.201200815.
G. S. Kumar, B. Pieber, K. R. Reddy, and C. O. Kappe, “Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats,” Chemistry - A European Journal, vol. 18, no. 20. Wiley, pp. 6124–6128, 2012.
Kumar GS, Pieber B, Reddy KR, Kappe CO. 2012. Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats. Chemistry - A European Journal. 18(20), 6124–6128.
Kumar, G. Sathish, et al. “Copper-Catalyzed Formation of C-O Bonds by Direct α-C-H Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous-Flow Formats.” Chemistry - A European Journal, vol. 18, no. 20, Wiley, 2012, pp. 6124–28, doi:10.1002/chem.201200815.
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