Molecular cloning and characterization of the rat NMDA receptor

Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. 1991. Molecular cloning and characterization of the rat NMDA receptor. Nature. 353(6348), 31–37.

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Journal Article | Published | English

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Author
Moriyoshi, Koki; Masu, Masayuki; Ishii, Takahiro; Shigemoto, RyuichiISTA ; Mizuno, Noboru; Nakanishi, Shigetada
Abstract
A complementary DNA encoding the rat NMDA receptor has been cloned and characterized. The single protein encoded by the cDNA forms a receptor-channel complex that has electrophysiological and pharmacological properties characteristic of the NMDA receptor. This protein has a significant sequence similarity to the AMPA/kainate receptors and contains four putative transmembrane segments following a large extracellular domain. The NMDA receptor messenger RNA is expressed in neuronal cells throughout the brain regions, particularly in the hippocampus, cerebral cortex and cerebellum.
Publishing Year
Date Published
1991-11-07
Journal Title
Nature
Volume
353
Issue
6348
Page
31 - 37
ISSN
eISSN
IST-REx-ID

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Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. Molecular cloning and characterization of the rat NMDA receptor. Nature. 1991;353(6348):31-37. doi:10.1038/354031a0
Moriyoshi, K., Masu, M., Ishii, T., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1991). Molecular cloning and characterization of the rat NMDA receptor. Nature. Nature Publishing Group. https://doi.org/10.1038/354031a0
Moriyoshi, Koki, Masayuki Masu, Takahiro Ishii, Ryuichi Shigemoto, Noboru Mizuno, and Shigetada Nakanishi. “Molecular Cloning and Characterization of the Rat NMDA Receptor.” Nature. Nature Publishing Group, 1991. https://doi.org/10.1038/354031a0.
K. Moriyoshi, M. Masu, T. Ishii, R. Shigemoto, N. Mizuno, and S. Nakanishi, “Molecular cloning and characterization of the rat NMDA receptor,” Nature, vol. 353, no. 6348. Nature Publishing Group, pp. 31–37, 1991.
Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. 1991. Molecular cloning and characterization of the rat NMDA receptor. Nature. 353(6348), 31–37.
Moriyoshi, Koki, et al. “Molecular Cloning and Characterization of the Rat NMDA Receptor.” Nature, vol. 353, no. 6348, Nature Publishing Group, 1991, pp. 31–37, doi:10.1038/354031a0.

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PMID: 1834949
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