A Mechanism for the Prebiotic Emergence of Proteins
de Vladar H, Cipriani R, Scharifker B, Bubis J. 2004.A Mechanism for the Prebiotic Emergence of Proteins. In: Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds. Cellular Origin, Life in Extreme Habitats and Astrobiology, vol. 7, 83–87.
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Book Chapter
| Published
| English
Scopus indexed
Author
Vladar, HaroldISTA 
;
Cipriani, Roberto;
Scharifker, Benjamin;
Bubis, Jose
;
Cipriani, Roberto;
Scharifker, Benjamin;
Bubis, JoseBook Editor
Seckbach, J.;
Chela Flores, J.;
Owen, T.;
Raulin, F.
Series Title
Cellular Origin, Life in Extreme Habitats and Astrobiology
Abstract
The first living organisms were not necessarily the result of the assembly of fully structured biochemical mechanisms involving macromolecules, but at least some life-related processes, as we know them today, probably appeared alongside the structural integration and early evolution of these proto-organisms. Along these ideas, we consider that spatial compartmentalization and protein functionality are tightly related in their origin. A possible scenario of this relationship is the early polymerization of amino acids (AA) embedded in amphiphilic membranes. The resulting membrane-embedded proto-proteins could have played an important role modulating the transport of elements or ions between the internal compartment and the environment. This scenario is congruent with selectivity arguments of AA (Hitz & DeLuisi, 2000) (i.e., 20 out of nearly 70 originally available (Croning & Chang, 1993; Engel & Nagy, 1982)) and their homochirality (Hitz et al., 2001). Other mechanisms of peptide bond formation, such as alumina-catalyzed reactions (Bujdak & Rode, 2002), polymerization on clay surfaces (Bujdak & Rode, 1996) and polymerization mediated by thioesters (De Duve, 1996), can also lead to this scenario.
Publishing Year
Date Published
2004-01-01
Book Title
Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds
Publisher
Springer
Volume
7
Page
83 - 87
IST-REx-ID
Cite this
de Vladar H, Cipriani R, Scharifker B, Bubis J. A Mechanism for the Prebiotic Emergence of Proteins. In: Seckbach J, Chela Flores J, Owen T, Raulin F, eds. Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds. Vol 7. COLE. Springer; 2004:83-87. doi:10.1007/978-94-007-1003-0_12
de Vladar, H., Cipriani, R., Scharifker, B., & Bubis, J. (2004). A Mechanism for the Prebiotic Emergence of Proteins. In J. Seckbach, J. Chela Flores, T. Owen, & F. Raulin (Eds.), Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds (Vol. 7, pp. 83–87). Springer. https://doi.org/10.1007/978-94-007-1003-0_12
Vladar, Harold de, Roberto Cipriani, Benjamin Scharifker, and Jose Bubis. “A Mechanism for the Prebiotic Emergence of Proteins.” In Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds, edited by J. Seckbach, J. Chela Flores, T. Owen, and F. Raulin, 7:83–87. COLE. Springer, 2004. https://doi.org/10.1007/978-94-007-1003-0_12.
H. de Vladar, R. Cipriani, B. Scharifker, and J. Bubis, “A Mechanism for the Prebiotic Emergence of Proteins,” in Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds, vol. 7, J. Seckbach, J. Chela Flores, T. Owen, and F. Raulin, Eds. Springer, 2004, pp. 83–87.
de Vladar H, Cipriani R, Scharifker B, Bubis J. 2004.A Mechanism for the Prebiotic Emergence of Proteins. In: Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds. Cellular Origin, Life in Extreme Habitats and Astrobiology, vol. 7, 83–87.
de Vladar, Harold, et al. “A Mechanism for the Prebiotic Emergence of Proteins.” Life in the Universe. From the Miller Experiment to the Search for Life on Other Worlds, edited by J. Seckbach et al., vol. 7, Springer, 2004, pp. 83–87, doi:10.1007/978-94-007-1003-0_12.
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