Specificity of oral immune priming in the red flour beetle Tribolium castaneum
Futo M, Sell M, Kutzer M, Kurtz J. 2017. Specificity of oral immune priming in the red flour beetle Tribolium castaneum. Biology Letters. 13(12), 0632.
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Journal Article
| Published
| English
Scopus indexed
Author
Futo, Momir;
Sell, Marie;
Kutzer, MeganISTA ;
Kurtz, Joachim
Department
Abstract
Immune specificity is the degree to which a host’s immune system discriminates among various pathogens or antigenic variants. Vertebrate immune memory is highly specific due to antibody responses. On the other hand, some invertebrates show immune priming, i.e. improved survival after secondary exposure to a previously encountered pathogen. Until now, specificity of priming has only been demonstrated via the septic infection route or when live pathogens were used for priming. Therefore, we tested for specificity in the oral priming route in the red flour beetle, Tribolium castaneum. For priming, we used pathogen-free supernatants derived from three different strains of the entomopathogen, Bacillus thuringiensis, which express different Cry toxin variants known for their toxicity against this beetle. Subsequent exposure to the infective spores showed that oral priming was specific for two naturally occurring strains, while a third engineered strain did not induce any priming effect. Our data demonstrate that oral immune priming with a non-infectious bacterial agent can be specific, but the priming effect is not universal across all bacterial strains.
Publishing Year
Date Published
2017-12-01
Journal Title
Biology Letters
Volume
13
Issue
12
Article Number
0632
ISSN
IST-REx-ID
Cite this
Futo M, Sell M, Kutzer M, Kurtz J. Specificity of oral immune priming in the red flour beetle Tribolium castaneum. Biology Letters. 2017;13(12). doi:10.1098/rsbl.2017.0632
Futo, M., Sell, M., Kutzer, M., & Kurtz, J. (2017). Specificity of oral immune priming in the red flour beetle Tribolium castaneum. Biology Letters. The Royal Society. https://doi.org/10.1098/rsbl.2017.0632
Futo, Momir, Marie Sell, Megan Kutzer, and Joachim Kurtz. “Specificity of Oral Immune Priming in the Red Flour Beetle Tribolium Castaneum.” Biology Letters. The Royal Society, 2017. https://doi.org/10.1098/rsbl.2017.0632.
M. Futo, M. Sell, M. Kutzer, and J. Kurtz, “Specificity of oral immune priming in the red flour beetle Tribolium castaneum,” Biology Letters, vol. 13, no. 12. The Royal Society, 2017.
Futo M, Sell M, Kutzer M, Kurtz J. 2017. Specificity of oral immune priming in the red flour beetle Tribolium castaneum. Biology Letters. 13(12), 0632.
Futo, Momir, et al. “Specificity of Oral Immune Priming in the Red Flour Beetle Tribolium Castaneum.” Biology Letters, vol. 13, no. 12, 0632, The Royal Society, 2017, doi:10.1098/rsbl.2017.0632.
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PMID: 29237813
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