Sandra Siegert
Siegert Group
22 Publications
2023 | Journal Article | IST-REx-ID: 14363 | 
Maes, Margaret E, Gloria Colombo, Florianne E Schoot Uiterkamp, Felix Sternberg, Alessandro Venturino, Elena E. Pohl, and Sandra Siegert. “Mitochondrial Network Adaptations of Microglia Reveal Sex-Specific Stress Response after Injury and UCP2 Knockout.” IScience. Elsevier, 2023. https://doi.org/10.1016/j.isci.2023.107780.
[Published Version]
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| PubMed | Europe PMC
2023 | Journal Article | IST-REx-ID: 14257 |
Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology. Springer Nature, 2023. https://doi.org/10.1038/s41587-023-01911-8.
[Published Version]
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2022 | Journal Article | IST-REx-ID: 11478 |
Bartalska, Katarina, Verena Hübschmann, Medina Korkut, Ryan J Cubero, Alessandro Venturino, Karl Rössler, Thomas Czech, and Sandra Siegert. “A Systematic Characterization of Microglia-like Cell Occurrence during Retinal Organoid Differentiation.” IScience. Elsevier, 2022. https://doi.org/10.1016/j.isci.2022.104580.
[Published Version]
View
| Files available
| DOI
| WoS
2022 | Journal Article | IST-REx-ID: 12117 |
Hübschmann, Verena, Medina Korkut, and Sandra Siegert. “Assessing Human IPSC-Derived Microglia Identity and Function by Immunostaining, Phagocytosis, Calcium Activity, and Inflammation Assay.” STAR Protocols. Elsevier, 2022. https://doi.org/10.1016/j.xpro.2022.101866.
[Published Version]
View
| Files available
| DOI
2022 | Journal Article | IST-REx-ID: 11995 |
Schulz, Rouven, Medina Korkut, Alessandro Venturino, Gloria Colombo, and Sandra Siegert. “Chimeric GPCRs Mimic Distinct Signaling Pathways and Modulate Microglia Responses.” Nature Communications. Springer Nature, 2022. https://doi.org/10.1038/s41467-022-32390-1.
[Published Version]
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| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 12244 |
Colombo, Gloria, Ryan J Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero, Jens Agerberg, et al. “A Tool for Mapping Microglial Morphology, MorphOMICs, Reveals Brain-Region and Sex-Dependent Phenotypes.” Nature Neuroscience. Springer Nature, 2022. https://doi.org/10.1038/s41593-022-01167-6.
[Published Version]
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| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Preprint | IST-REx-ID: 11950 |
Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Uncovering Brain Tissue Architecture across Scales with Super-Resolution Light Microscopy.” BioRxiv. Cold Spring Harbor Laboratory, n.d. https://doi.org/10.1101/2022.08.17.504272.
[Preprint]
View
| Files available
| DOI
| Download Preprint (ext.)
2021 | Journal Article | IST-REx-ID: 9642 |
Venturino, Alessandro, Rouven Schulz, Héctor De Jesús-Cortés, Margaret E Maes, Balint Nagy, Francis Reilly-Andújar, Gloria Colombo, et al. “Microglia Enable Mature Perineuronal Nets Disassembly upon Anesthetic Ketamine Exposure or 60-Hz Light Entrainment in the Healthy Brain.” Cell Reports. Elsevier, 2021. https://doi.org/10.1016/j.celrep.2021.109313.
[Published Version]
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| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 10655 |
Maes, Margaret E, Gabriele M. Wögenstein, Gloria Colombo, Raquel Casado Polanco, and Sandra Siegert. “Optimizing AAV2/6 Microglial Targeting Identified Enhanced Efficiency in the Photoreceptor Degenerative Environment.” Molecular Therapy - Methods and Clinical Development. Elsevier, 2021. https://doi.org/10.1016/j.omtm.2021.09.006.
[Published Version]
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| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 10565 |
Venturino, Alessandro, and Sandra Siegert. “Minimally Invasive Protocols and Quantification for Microglia-Mediated Perineuronal Net Disassembly in Mouse Brain.” STAR Protocols. Elsevier ; Cell Press, 2021. https://doi.org/10.1016/j.xpro.2021.101012.
[Published Version]
View
| Files available
| DOI
2019 | Journal Article | IST-REx-ID: 6521 |
Maes, Margaret E, Gloria Colombo, Rouven Schulz, and Sandra Siegert. “Targeting Microglia with Lentivirus and AAV: Recent Advances and Remaining Challenges.” Neuroscience Letters. Elsevier, 2019. https://doi.org/10.1016/j.neulet.2019.134310.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2016 | Journal Article | IST-REx-ID: 1613 |
Mungenast, Alison, Sandra Siegert, and Li Tsai. “Modeling Alzheimer’s Disease with Human Induced Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience. Academic Press, 2016. https://doi.org/doi:10.1016/j.mcn.2015.11.010.
[Submitted Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 1253 |
Tsai, Lihuei, and Sandra Siegert. “How MicroRNAs Are Involved in Splitting the Mind.” JAMA Psychiatry. American Medical Association, 2016. https://doi.org/10.1001/jamapsychiatry.2015.3144.
[Submitted Version]
View
| Files available
| DOI
| PubMed | Europe PMC
2015 | Journal Article | IST-REx-ID: 1803
Rei, Damien, Xenos Mason, Jinsoo Seo, Johannes Gräff, Andrii Rudenko, Jùn Wang, Richard Rueda, et al. “Basolateral Amygdala Bidirectionally Modulates Stress Induced Hippocampal Learning and Memory Deficits through a P25/Cdk5-Dependent Pathway.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1415845112.
View
| DOI
2015 | Journal Article | IST-REx-ID: 1802
Siegert, Sandra, Jinsoo Seo, Ester Kwon, Andrii Rudenko, Sukhee Cho, Wenyuan Wang, Zachary Flood, et al. “The Schizophrenia Risk Gene Product MiR-137 Alters Presynaptic Plasticity.” Nature Neuroscience. Nature Publishing Group, 2015. https://doi.org/10.1038/nn.4023.
View
| DOI
2012 | Journal Article | IST-REx-ID: 1801
Siegert, Sandra, Erik Cabuy, Brigitte Scherf, Hubertus Kohler, Satchidananda Panda, Yunzheng Le, Hans Fehling, Dimos Gaidatzis, Michael Stadler, and Botond Roska. “Transcriptional Code and Disease Map for Adult Retinal Cell Types.” Nature Neuroscience. Nature Publishing Group, 2012. https://doi.org/10.1038/nn.3032.
View
| DOI
2010 | Journal Article | IST-REx-ID: 1800
Busskamp, Volker, Jens Duebel, Dávid Bálya, Mathias Fradot, Tim Viney, Sandra Siegert, Anna Groner, et al. “Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa.” Science. American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1190897.
View
| DOI
2009 | Journal Article | IST-REx-ID: 1799
Münch, Thomas, Ravá Da Silveira, Sandra Siegert, Tim Viney, Gautam Awatramani, and Botond Roska. “Approach Sensitivity in the Retina Processed by a Multifunctional Neural Circuit.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2389.
View
| DOI
2009 | Journal Article | IST-REx-ID: 1798
Siegert, Sandra, Brigitte Scherf, Karina Del Punta, Nick Didkovsky, Nathaniel Heintz, and Botond Roska. “Genetic Address Book for Retinal Cell Types.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2370.
View
| DOI
2007 | Journal Article | IST-REx-ID: 1797
Viney, Tim, Kamill Bálint, Dániel Hillier, Sandra Siegert, Zsolt Boldogköi, Lynn Enquist, Markus Meister, Constance Cepko, and Botond Roska. “Local Retinal Circuits of Melanopsin-Containing Ganglion Cells Identified by Transsynaptic Viral Tracing.” Current Biology. Cell Press, 2007. https://doi.org/10.1016/j.cub.2007.04.058.
View
| DOI
2006 | Journal Article | IST-REx-ID: 1796
Siegert, Sandra, Peter Schnierle, and Barbara Schnierle. “Novel Anti-Viral Therapy: Drugs That Block HIV Entry at Different Target Sites.” Mini-Reviews in Medicinal Chemistry. Bentham Science Publishers, 2006. https://doi.org/10.2174/138955706776876267.
View
| DOI
2005 | Journal Article | IST-REx-ID: 1795
Siegert, Sandra, Sonja Thaler, Ralf Wagner, and Barbara Schnierle. “Assessment of HIV-1 Entry Inhibitors by MLV/HIV-1 Pseudotyped Vectors.” AIDS Research and Therapy. BioMed Central, 2005. https://doi.org/10.1186/1742-6405-2-7.
View
| DOI
22 Publications
2023 | Journal Article | IST-REx-ID: 14363 |
Maes, Margaret E, Gloria Colombo, Florianne E Schoot Uiterkamp, Felix Sternberg, Alessandro Venturino, Elena E. Pohl, and Sandra Siegert. “Mitochondrial Network Adaptations of Microglia Reveal Sex-Specific Stress Response after Injury and UCP2 Knockout.” IScience. Elsevier, 2023. https://doi.org/10.1016/j.isci.2023.107780.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2023 | Journal Article | IST-REx-ID: 14257 |
Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Imaging Brain Tissue Architecture across Millimeter to Nanometer Scales.” Nature Biotechnology. Springer Nature, 2023. https://doi.org/10.1038/s41587-023-01911-8.
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
2022 | Journal Article | IST-REx-ID: 11478 |
Bartalska, Katarina, Verena Hübschmann, Medina Korkut, Ryan J Cubero, Alessandro Venturino, Karl Rössler, Thomas Czech, and Sandra Siegert. “A Systematic Characterization of Microglia-like Cell Occurrence during Retinal Organoid Differentiation.” IScience. Elsevier, 2022. https://doi.org/10.1016/j.isci.2022.104580.
[Published Version]
View
| Files available
| DOI
| WoS
2022 | Journal Article | IST-REx-ID: 12117 |
Hübschmann, Verena, Medina Korkut, and Sandra Siegert. “Assessing Human IPSC-Derived Microglia Identity and Function by Immunostaining, Phagocytosis, Calcium Activity, and Inflammation Assay.” STAR Protocols. Elsevier, 2022. https://doi.org/10.1016/j.xpro.2022.101866.
[Published Version]
View
| Files available
| DOI
2022 | Journal Article | IST-REx-ID: 11995 |
Schulz, Rouven, Medina Korkut, Alessandro Venturino, Gloria Colombo, and Sandra Siegert. “Chimeric GPCRs Mimic Distinct Signaling Pathways and Modulate Microglia Responses.” Nature Communications. Springer Nature, 2022. https://doi.org/10.1038/s41467-022-32390-1.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 12244 |
Colombo, Gloria, Ryan J Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero, Jens Agerberg, et al. “A Tool for Mapping Microglial Morphology, MorphOMICs, Reveals Brain-Region and Sex-Dependent Phenotypes.” Nature Neuroscience. Springer Nature, 2022. https://doi.org/10.1038/s41593-022-01167-6.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Preprint | IST-REx-ID: 11950 |
Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Uncovering Brain Tissue Architecture across Scales with Super-Resolution Light Microscopy.” BioRxiv. Cold Spring Harbor Laboratory, n.d. https://doi.org/10.1101/2022.08.17.504272.
[Preprint]
View
| Files available
| DOI
| Download Preprint (ext.)
2021 | Journal Article | IST-REx-ID: 9642 |
Venturino, Alessandro, Rouven Schulz, Héctor De Jesús-Cortés, Margaret E Maes, Balint Nagy, Francis Reilly-Andújar, Gloria Colombo, et al. “Microglia Enable Mature Perineuronal Nets Disassembly upon Anesthetic Ketamine Exposure or 60-Hz Light Entrainment in the Healthy Brain.” Cell Reports. Elsevier, 2021. https://doi.org/10.1016/j.celrep.2021.109313.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 10655 |
Maes, Margaret E, Gabriele M. Wögenstein, Gloria Colombo, Raquel Casado Polanco, and Sandra Siegert. “Optimizing AAV2/6 Microglial Targeting Identified Enhanced Efficiency in the Photoreceptor Degenerative Environment.” Molecular Therapy - Methods and Clinical Development. Elsevier, 2021. https://doi.org/10.1016/j.omtm.2021.09.006.
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 10565 |
Venturino, Alessandro, and Sandra Siegert. “Minimally Invasive Protocols and Quantification for Microglia-Mediated Perineuronal Net Disassembly in Mouse Brain.” STAR Protocols. Elsevier ; Cell Press, 2021. https://doi.org/10.1016/j.xpro.2021.101012.
[Published Version]
View
| Files available
| DOI
2019 | Journal Article | IST-REx-ID: 6521 |
Maes, Margaret E, Gloria Colombo, Rouven Schulz, and Sandra Siegert. “Targeting Microglia with Lentivirus and AAV: Recent Advances and Remaining Challenges.” Neuroscience Letters. Elsevier, 2019. https://doi.org/10.1016/j.neulet.2019.134310.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2016 | Journal Article | IST-REx-ID: 1613 |
Mungenast, Alison, Sandra Siegert, and Li Tsai. “Modeling Alzheimer’s Disease with Human Induced Pluripotent Stem (IPS) Cells.” Molecular and Cellular Neuroscience. Academic Press, 2016. https://doi.org/doi:10.1016/j.mcn.2015.11.010.
[Submitted Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 1253 |
Tsai, Lihuei, and Sandra Siegert. “How MicroRNAs Are Involved in Splitting the Mind.” JAMA Psychiatry. American Medical Association, 2016. https://doi.org/10.1001/jamapsychiatry.2015.3144.
[Submitted Version]
View
| Files available
| DOI
| PubMed | Europe PMC
2015 | Journal Article | IST-REx-ID: 1803
Rei, Damien, Xenos Mason, Jinsoo Seo, Johannes Gräff, Andrii Rudenko, Jùn Wang, Richard Rueda, et al. “Basolateral Amygdala Bidirectionally Modulates Stress Induced Hippocampal Learning and Memory Deficits through a P25/Cdk5-Dependent Pathway.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1415845112.
View
| DOI
2015 | Journal Article | IST-REx-ID: 1802
Siegert, Sandra, Jinsoo Seo, Ester Kwon, Andrii Rudenko, Sukhee Cho, Wenyuan Wang, Zachary Flood, et al. “The Schizophrenia Risk Gene Product MiR-137 Alters Presynaptic Plasticity.” Nature Neuroscience. Nature Publishing Group, 2015. https://doi.org/10.1038/nn.4023.
View
| DOI
2012 | Journal Article | IST-REx-ID: 1801
Siegert, Sandra, Erik Cabuy, Brigitte Scherf, Hubertus Kohler, Satchidananda Panda, Yunzheng Le, Hans Fehling, Dimos Gaidatzis, Michael Stadler, and Botond Roska. “Transcriptional Code and Disease Map for Adult Retinal Cell Types.” Nature Neuroscience. Nature Publishing Group, 2012. https://doi.org/10.1038/nn.3032.
View
| DOI
2010 | Journal Article | IST-REx-ID: 1800
Busskamp, Volker, Jens Duebel, Dávid Bálya, Mathias Fradot, Tim Viney, Sandra Siegert, Anna Groner, et al. “Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa.” Science. American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1190897.
View
| DOI
2009 | Journal Article | IST-REx-ID: 1799
Münch, Thomas, Ravá Da Silveira, Sandra Siegert, Tim Viney, Gautam Awatramani, and Botond Roska. “Approach Sensitivity in the Retina Processed by a Multifunctional Neural Circuit.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2389.
View
| DOI
2009 | Journal Article | IST-REx-ID: 1798
Siegert, Sandra, Brigitte Scherf, Karina Del Punta, Nick Didkovsky, Nathaniel Heintz, and Botond Roska. “Genetic Address Book for Retinal Cell Types.” Nature Neuroscience. Nature Publishing Group, 2009. https://doi.org/10.1038/nn.2370.
View
| DOI
2007 | Journal Article | IST-REx-ID: 1797
Viney, Tim, Kamill Bálint, Dániel Hillier, Sandra Siegert, Zsolt Boldogköi, Lynn Enquist, Markus Meister, Constance Cepko, and Botond Roska. “Local Retinal Circuits of Melanopsin-Containing Ganglion Cells Identified by Transsynaptic Viral Tracing.” Current Biology. Cell Press, 2007. https://doi.org/10.1016/j.cub.2007.04.058.
View
| DOI
2006 | Journal Article | IST-REx-ID: 1796
Siegert, Sandra, Peter Schnierle, and Barbara Schnierle. “Novel Anti-Viral Therapy: Drugs That Block HIV Entry at Different Target Sites.” Mini-Reviews in Medicinal Chemistry. Bentham Science Publishers, 2006. https://doi.org/10.2174/138955706776876267.
View
| DOI
2005 | Journal Article | IST-REx-ID: 1795
Siegert, Sandra, Sonja Thaler, Ralf Wagner, and Barbara Schnierle. “Assessment of HIV-1 Entry Inhibitors by MLV/HIV-1 Pseudotyped Vectors.” AIDS Research and Therapy. BioMed Central, 2005. https://doi.org/10.1186/1742-6405-2-7.
View
| DOI