Limits to selection in biology and in evolutionary computation

Project Period: 2010-07-01 – 2015-06-30
Externally Funded
Acronym
SelectionInformation
Principal Investigator
Nicholas H Barton
Department(s)
Barton Group
Grant Number
250152
Funding Organisation
EC/FP7

53 Publications

2017 | Journal Article | IST-REx-ID: 1191 | OA
Existence of traveling waves for the generalized F–KPP equation
R. Kollár, S. Novak, Bulletin of Mathematical Biology 79 (2017) 525–559.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Journal Article | IST-REx-ID: 1195 | OA
Reconstruction of haplotype-blocks selected during experimental evolution.
S. Franssen, N.H. Barton, C. Schlötterer, Molecular Biology and Evolution 34 (2016) 174–184.
[Submitted Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1241 | OA
The role of recombination in evolutionary rescue
H. Uecker, J. Hermisson, Genetics 202 (2016) 721–732.
[Preprint] View | DOI | Download Preprint (ext.)
 
2016 | Journal Article | IST-REx-ID: 1359 | OA
The effect of gene interactions on the long-term response to selection
T. Paixao, N.H. Barton, PNAS 113 (2016) 4422–4427.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
2016 | Journal Article | IST-REx-ID: 1420 | OA
A general approximation for the dynamics of quantitative traits
K. Bodova, G. Tkačik, N.H. Barton, Genetics 202 (2016) 1523–1548.
[Preprint] View | DOI | Download Preprint (ext.) | arXiv
 
2016 | Journal Article | IST-REx-ID: 1518 | OA
Efficient strategies for calculating blockwise likelihoods under the coalescent
K. Lohse, M. Chmelik, S. Martin, N.H. Barton, Genetics 202 (2016) 775–786.
[Preprint] View | Files available | DOI | PubMed | Europe PMC
 
2015 | Journal Article | IST-REx-ID: 1519 | OA
The interpretation of selection coefficients
N.H. Barton, M. Servedio, Evolution 69 (2015) 1101–1112.
[Submitted Version] View | Files available | DOI
 
2015 | Journal Article | IST-REx-ID: 1542 | OA
Toward a unifying framework for evolutionary processes
T. Paixao, G. Badkobeh, N.H. Barton, D. Çörüş, D. Dang, T. Friedrich, P. Lehre, D. Sudholt, A. Sutton, B. Trubenova, Journal of Theoretical Biology 383 (2015) 28–43.
[Published Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1631 | OA
Spread of pedigree versus genetic ancestry in spatially distributed populations
J. Kelleher, A. Etheridge, A. Véber, N.H. Barton, Theoretical Population Biology 108 (2016) 1–12.
[Published Version] View | Files available | DOI
 
2015 | Journal Article | IST-REx-ID: 1818 | OA
Limits to adaptation along environmental gradients
J. Polechova, N.H. Barton, PNAS 112 (2015) 6401–6406.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2015 | Journal Article | IST-REx-ID: 1850 | OA
Fungal disease dynamics in insect societies: Optimal killing rates and the ambivalent effect of high social interaction rates
S. Novak, S. Cremer, Journal of Theoretical Biology 372 (2015) 54–64.
[Submitted Version] View | Files available | DOI
 
2014 | Journal Article | IST-REx-ID: 1908 | OA
The rate of adaptation in large sexual populations with linear chromosomes
D. Weissman, O. Hallatschek, Genetics 196 (2014) 1167–1183.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2014 | Journal Article | IST-REx-ID: 1936 | OA
An arms race between producers and scroungers can drive the evolution of social cognition
M. Arbilly, D. Weissman, M. Feldman, U. Grodzinski, Behavioral Ecology 25 (2014) 487–495.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2014 | Journal Article | IST-REx-ID: 1932 | OA
Cryptic genetic variation can make "irreducible complexity" a common mode of adaptation in sexual populations
M. Trotter, D. Weissman, G. Peterson, K. Peck, J. Masel, Evolution 68 (2014) 3357–3367.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2014 | Journal Article | IST-REx-ID: 2168 | OA
Coalescent simulation in continuous space: Algorithms for large neighbourhood size
J. Kelleher, A. Etheridge, N.H. Barton, Theoretical Population Biology 95 (2014) 13–23.
[Published Version] View | Files available | DOI
 
2014 | Journal Article | IST-REx-ID: 2174 | OA
Stability and response of polygenic traits to stabilizing selection and mutation
H. De Vladar, N.H. Barton, Genetics 197 (2014) 749–767.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2013 | Journal Article | IST-REx-ID: 2473 | OA
Genetic hitch-hiking in spatially extended populations
N.H. Barton, A. Etheridge, J. Kelleher, A. Véber, Theoretical Population Biology 87 (2013) 75–89.
[Submitted Version] View | Files available | DOI
 
2013 | Conference Paper | IST-REx-ID: 2718 | OA
Can quantitative and population genetics help us understand evolutionary computation?
N.H. Barton, T. Paixao, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 1573–1580.
[Submitted Version] View | Files available | DOI
 
2013 | Journal Article | IST-REx-ID: 2720 | OA
Accumulation of spontaneous mutations in the ciliate Tetrahymena thermophila
H. Long, T. Paixao, R. Azevedo, R. Zufall, Genetics 195 (2013) 527–540.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2013 | Conference Paper | IST-REx-ID: 2719
A variance decomposition approach to the analysis of genetic algorithms
T. Paixao, N.H. Barton, in:, Proceedings of the 15th Annual Conference on Genetic and Evolutionary Computation, ACM, 2013, pp. 845–852.
View | DOI
 
2013 | Journal Article | IST-REx-ID: 2817 | OA
Density games
S. Novak, K. Chatterjee, M. Nowak, Journal of Theoretical Biology 334 (2013) 26–34.
[Published Version] View | Files available | DOI
 
2013 | Journal Article | IST-REx-ID: 2842 | OA
Inference in two dimensions: Allele frequencies versus lengths of shared sequence blocks
N.H. Barton, A. Etheridge, J. Kelleher, A. Véber, Theoretical Population Biology 87 (2013) 105–119.
[Submitted Version] View | Files available | DOI
 
2013 | Journal Article | IST-REx-ID: 2910 | OA
Coalescent simulation in continuous space
J. Kelleher, N.H. Barton, A. Etheridge, Bioinformatics 29 (2013) 955–956.
[Published Version] View | Files available | DOI
 
2013 | Journal Article | IST-REx-ID: 2909 | OA
Modelling evolution in a spatial continuum
N.H. Barton, A. Etheridge, A. Véber, Journal of Statistical Mechanics Theory and Experiment 2013 (2013).
[Submitted Version] View | Files available | DOI
 
2012 | Journal Article | IST-REx-ID: 3131 | OA
Limits to the rate of adaptive substitution in sexual populations
D. Weissman, N.H. Barton, PLoS Genetics 8 (2012).
[Published Version] View | Files available | DOI
 
2012 | Journal Article | IST-REx-ID: 3166 | OA
Amino acid fermentation at the origin of the genetic code
H. de Vladar, Biology Direct 7 (2012).
[Published Version] View | Files available | DOI
 
2010 | Journal Article | IST-REx-ID: 3303 | OA
The rate of fitness-valley crossing in sexual populations
D. Weissman, M. Feldman, D. Fisher, Genetics 186 (2010) 1389–1410.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2011 | Journal Article | IST-REx-ID: 3394 | OA
Genetic drift widens the expected cline but narrows the expected cline width
J. Polechova, N.H. Barton, Genetics 189 (2011) 227–235.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2011 | Journal Article | IST-REx-ID: 3390 | OA
The relation between reproductive value and genetic contribution
N.H. Barton, A. Etheridge, Genetics 188 (2011) 953–973.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2011 | Journal Article | IST-REx-ID: 3391 | OA
The contribution of statistical physics to evolutionary biology
H. de Vladar, N.H. Barton, Trends in Ecology and Evolution 26 (2011) 424–432.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2011 | Journal Article | IST-REx-ID: 3290 | OA
A general method for calculating likelihoods under the coalescent process
K. Lohse, R. Harrison, N.H. Barton, Genetics 189 (2011) 977–987.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
2017 | Journal Article | IST-REx-ID: 626 | OA
The infinitesimal model: Definition derivation and implications
N.H. Barton, A. Etheridge, A. Véber, Theoretical Population Biology 118 (2017) 50–73.
[Published Version] View | Files available | DOI
 
2012 | Journal Article | IST-REx-ID: 2968 | OA
A likelihood based comparison of population histories in a parasitoid guild
K. Lohse, N.H. Barton, G. Melika, G. Stone, Molecular Ecology 21 (2012) 4605–4617.
[Submitted Version] View | Files available | DOI
 
2021 | Journal Article | IST-REx-ID: 9410 | OA
Adaptation at different points along antibiotic concentration gradients
M. Lagator, H. Uecker, P. Neve, Biology Letters 17 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2015 | Journal Article | IST-REx-ID: 1666 | OA
Dynamics of transcription factor binding site evolution
M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, PLoS Genetics 11 (2015).
[Published Version] View | Files available | DOI
 
2014 | Journal Article | IST-REx-ID: 2023 | OA
Habitat heterogeneities versus spatial type frequency variances as driving forces of dispersal evolution
S. Novak, Ecology and Evolution 4 (2014) 4589–4597.
[Published Version] View | Files available | DOI
 
2016 | Journal Article | IST-REx-ID: 1358 | OA
Intrinsic limits to gene regulation by global crosstalk
T. Friedlander, R. Prizak, C.C. Guet, N.H. Barton, G. Tkačik, Nature Communications 7 (2016).
[Published Version] View | Files available | DOI
 
2015 | Journal Article | IST-REx-ID: 1576 | OA
Stochastic proofreading mechanism alleviates crosstalk in transcriptional regulation
S.A. Cepeda Humerez, G. Rieckh, G. Tkačik, Physical Review Letters 115 (2015).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2018 | Journal Article | IST-REx-ID: 564 | OA
Establishment in a new habitat by polygenic adaptation
N.H. Barton, A. Etheridge, Theoretical Population Biology 122 (2018) 110–127.
[Submitted Version] View | Files available | DOI | WoS
 
2018 | Journal Article | IST-REx-ID: 316 | OA
Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system
K. Bodova, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018) 861–883.
[Preprint] View | Files available | DOI | Download Preprint (ext.) | WoS
 
2017 | Journal Article | IST-REx-ID: 1351 | OA
Model checking the evolution of gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, Acta Informatica 54 (2017) 765–787.
[Published Version] View | Files available | DOI | WoS
 
2015 | Conference Paper | IST-REx-ID: 1835 | OA
Model checking gene regulatory networks
M. Giacobbe, C.C. Guet, A. Gupta, T.A. Henzinger, T. Paixao, T. Petrov, 9035 (2015) 469–483.
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
2017 | Journal Article | IST-REx-ID: 1199 | OA
How does epistasis influence the response to selection?
N.H. Barton, Heredity 118 (2017) 96–109.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS
 
2017 | Journal Article | IST-REx-ID: 1169 | OA
Spatial gene frequency waves under genotype dependent dispersal
S. Novak, R. Kollár, Genetics 205 (2017) 367–374.
[Submitted Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1077 | OA
Evolutionary interplay between structure, energy and epistasis in the coat protein of the ϕX174 phage family
R.A. Fernandes Redondo, H. de Vladar, T. Włodarski, J.P. Bollback, Journal of the Royal Society Interface 14 (2017).
[Published Version] View | Files available | DOI | WoS
 
2017 | Journal Article | IST-REx-ID: 1074 | OA
Inferring recent demography from isolation by distance of long shared sequence blocks
H. Ringbauer, G. Coop, N.H. Barton, Genetics 205 (2017) 1335–1351.
[Preprint] View | Files available | DOI | Download Preprint (ext.) | WoS
 
2017 | Journal Article | IST-REx-ID: 1063 | OA
Evolutionary rescue in randomly mating, selfing, and clonal populations
H. Uecker, Evolution 71 (2017) 845–858.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS
 
2017 | Journal Article | IST-REx-ID: 990 | OA
Divergence and evolution of assortative mating in a polygenic trait model of speciation with gene flow
H. Sachdeva, N.H. Barton, Evolution; International Journal of Organic Evolution 71 (2017) 1478–1493.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2017 | Journal Article | IST-REx-ID: 955 | OA
Evolution of new regulatory functions on biophysically realistic fitness landscapes
T. Friedlander, R. Prizak, N.H. Barton, G. Tkačik, Nature Communications 8 (2017).
[Published Version] View | Files available | DOI | WoS
 
2011 | Journal Article | IST-REx-ID: 3375 | OA
The statistical mechanics of a polygenic character under stabilizing selection mutation and drift
H. de Vladar, N.H. Barton, Journal of the Royal Society Interface 8 (2011) 720–739.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
2023 | Journal Article | IST-REx-ID: 14452 | OA
The infinitesimal model with dominance
N.H. Barton, A.M. Etheridge, A. Véber, Genetics 225 (2023).
[Published Version] View | Files available | DOI | arXiv
 
2018 | Journal Article | IST-REx-ID: 286
Efficient inference of paternity and sibship inference given known maternity via hierarchical clustering
T. Ellis, D. Field, N.H. Barton, Molecular Ecology Resources 18 (2018) 988–999.
View | Files available | DOI | WoS
 
2022 | Journal Article | IST-REx-ID: 12081 | OA
Accumulation and maintenance of information in evolution
M. Hledik, N.H. Barton, G. Tkačik, Proceedings of the National Academy of Sciences 119 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC