The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
Hetzer M, Gruss OJ, Mattaj IW. 2002. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nature Cell Biology. 4(7), E177–E184.
Download
No fulltext has been uploaded. References only!
Journal Article
| Published
| English
Scopus indexed
Author
Hetzer, MartinISTA ;
Gruss, Oliver J.;
Mattaj, Iain W.
Abstract
The small GTPase Ran is a key regulator of nucleocytoplasmic transport during interphase. The asymmetric distribution of the GTP-bound form of Ran across the nuclear envelope — that is, large quantities in the nucleus compared with small quantities in the cytoplasm — determines the directionality of many nuclear transport processes. Recent findings that Ran also functions in spindle formation and nuclear envelope assembly during mitosis suggest that Ran has a general role in chromatin-centred processes. Ran functions in these events as a signal for chromosome position.
Keywords
Publishing Year
Date Published
2002-07-01
Journal Title
Nature Cell Biology
Volume
4
Issue
7
Page
E177-E184
ISSN
eISSN
IST-REx-ID
Cite this
Hetzer M, Gruss OJ, Mattaj IW. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nature Cell Biology. 2002;4(7):E177-E184. doi:10.1038/ncb0702-e177
Hetzer, M., Gruss, O. J., & Mattaj, I. W. (2002). The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nature Cell Biology. Springer Nature. https://doi.org/10.1038/ncb0702-e177
Hetzer, Martin, Oliver J. Gruss, and Iain W. Mattaj. “The Ran GTPase as a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.” Nature Cell Biology. Springer Nature, 2002. https://doi.org/10.1038/ncb0702-e177.
M. Hetzer, O. J. Gruss, and I. W. Mattaj, “The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly,” Nature Cell Biology, vol. 4, no. 7. Springer Nature, pp. E177–E184, 2002.
Hetzer M, Gruss OJ, Mattaj IW. 2002. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nature Cell Biology. 4(7), E177–E184.
Hetzer, Martin, et al. “The Ran GTPase as a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.” Nature Cell Biology, vol. 4, no. 7, Springer Nature, 2002, pp. E177–84, doi:10.1038/ncb0702-e177.
Export
Marked PublicationsOpen Data ISTA Research Explorer
Sources
PMID: 12105431
PubMed | Europe PMC