The Decapentaplegic morphogen gradient a precise definition
Kicheva A, González Gaitán M. 2008. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 20(2), 137–143.
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Journal Article
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Author
Kicheva, AnnaISTA 
;
González-Gaitán, Marcos A
;
González-Gaitán, Marcos AAbstract
Two key processes are in the basis of morphogenesis: the spatial allocation of cell types in fields of naïve cells and the regulation of growth. Both are controlled by morphogens, which activate target genes in the growing tissue in a concentration-dependent manner. Thus the morphogen model is an intrinsically quantitative concept. However, quantitative studies were performed only in recent years on two morphogens: Bicoid and Decapentaplegic. This review covers quantitative aspects of the formation and precision of the Decapentaplegic morphogen gradient. The morphogen gradient concept is transitioning from a soft definition to a precise idea of what the gradient could really do.
Publishing Year
Date Published
2008-04-01
Journal Title
Current Opinion in Cell Biology
Publisher
Elsevier
Acknowledgement
This work was supported by the University of Geneva, Max Planck Society, VW, EU, SNF, and HFSP
Volume
20
Issue
2
Page
137 - 143
IST-REx-ID
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Kicheva A, González Gaitán M. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 2008;20(2):137-143. doi:10.1016/j.ceb.2008.01.008
Kicheva, A., & González Gaitán, M. (2008). The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. Elsevier. https://doi.org/10.1016/j.ceb.2008.01.008
Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” Current Opinion in Cell Biology. Elsevier, 2008. https://doi.org/10.1016/j.ceb.2008.01.008.
A. Kicheva and M. González Gaitán, “The Decapentaplegic morphogen gradient a precise definition,” Current Opinion in Cell Biology, vol. 20, no. 2. Elsevier, pp. 137–143, 2008.
Kicheva A, González Gaitán M. 2008. The Decapentaplegic morphogen gradient a precise definition. Current Opinion in Cell Biology. 20(2), 137–143.
Kicheva, Anna, and Marcos González Gaitán. “The Decapentaplegic Morphogen Gradient a Precise Definition.” Current Opinion in Cell Biology, vol. 20, no. 2, Elsevier, 2008, pp. 137–43, doi:10.1016/j.ceb.2008.01.008.
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