Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex
Mandal PK, Venkadesh S, Gautham N. 2012. Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. Acta Crystallographica Section F Structural Biology Communications. 68(4), 393–399.
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Journal Article
| Published
| English
Author
Mandal, Pradeep KISTA 
;
Venkadesh, Sarkarai;
Gautham, Namasivayam
;
Venkadesh, Sarkarai;
Gautham, NamasivayamAbstract
The crystal structure of the tetradecanucleotide sequence d(CCCCGGTACCGGGG)2 has been determined at 2.5 Å resolution in the tetragonal space group P41. This sequence was designed with the expectation of a four-way junction. However, the sequence crystallized as an A-DNA duplex and represents more than one full turn of the A-helix. The crystallographic asymmetric unit consists of one tetradecanucleotide duplex. The structural parameters of the A-type DNA duplex structure and the crystal-packing arrangement are described. One Mn2+ ion was identified with direct coordination to the N7 position of G13 and a water molecule at the major-groove side of the C2·G13 base pair.
Publishing Year
Date Published
2012-04-01
Journal Title
Acta Crystallographica Section F Structural Biology Communications
Publisher
International Union of Crystallography
Volume
68
Issue
4
Page
393-399
ISSN
IST-REx-ID
Cite this
Mandal PK, Venkadesh S, Gautham N. Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. Acta Crystallographica Section F Structural Biology Communications. 2012;68(4):393-399. doi:10.1107/s174430911200869x
Mandal, P. K., Venkadesh, S., & Gautham, N. (2012). Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. Acta Crystallographica Section F Structural Biology Communications. International Union of Crystallography. https://doi.org/10.1107/s174430911200869x
Mandal, Pradeep K, Sarkarai Venkadesh, and Namasivayam Gautham. “Structure of the Tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA Duplex.” Acta Crystallographica Section F Structural Biology Communications. International Union of Crystallography, 2012. https://doi.org/10.1107/s174430911200869x.
P. K. Mandal, S. Venkadesh, and N. Gautham, “Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex,” Acta Crystallographica Section F Structural Biology Communications, vol. 68, no. 4. International Union of Crystallography, pp. 393–399, 2012.
Mandal PK, Venkadesh S, Gautham N. 2012. Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex. Acta Crystallographica Section F Structural Biology Communications. 68(4), 393–399.
Mandal, Pradeep K., et al. “Structure of the Tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA Duplex.” Acta Crystallographica Section F Structural Biology Communications, vol. 68, no. 4, International Union of Crystallography, 2012, pp. 393–99, doi:10.1107/s174430911200869x.
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