Facile access to foldable redox-active flavin-peptide conjugates

Stricker FJ, Kölsch JC, Beil SB, Preiß S, Waldvogel SR, Opatz T, Besenius P. 2021. Facile access to foldable redox-active flavin-peptide conjugates. Organic & Biomolecular Chemistry. 19(20), 4483–4486.

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Journal Article | Published | English

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Author
Stricker, Friedrich JISTA; Kölsch, Jonas Christopher; Beil, Sebastian B.; Preiß, Sebastian; Waldvogel, Siegfried R.; Opatz, Till; Besenius, Pol
Abstract
A convenient approach for the synthesis of foldable redox-active flavin peptide conjugates was established. A model β-hairpin oligopeptide motif was utilized to demonstrate that azidolysine side-chains are readily functionalised with an alkyne-bearing flavine derivative. The folding equilibrium of the peptide backbone as well as the redox behaviour of the flavin moieties remains intact after the conjugation.
Publishing Year
Date Published
2021-04-27
Journal Title
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry
Volume
19
Issue
20
Page
4483-4486
ISSN
eISSN
IST-REx-ID

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Stricker FJ, Kölsch JC, Beil SB, et al. Facile access to foldable redox-active flavin-peptide conjugates. Organic & Biomolecular Chemistry. 2021;19(20):4483-4486. doi:10.1039/d1ob00414j
Stricker, F. J., Kölsch, J. C., Beil, S. B., Preiß, S., Waldvogel, S. R., Opatz, T., & Besenius, P. (2021). Facile access to foldable redox-active flavin-peptide conjugates. Organic & Biomolecular Chemistry. Royal Society of Chemistry. https://doi.org/10.1039/d1ob00414j
Stricker, Friedrich J, Jonas Christopher Kölsch, Sebastian B. Beil, Sebastian Preiß, Siegfried R. Waldvogel, Till Opatz, and Pol Besenius. “Facile Access to Foldable Redox-Active Flavin-Peptide Conjugates.” Organic & Biomolecular Chemistry. Royal Society of Chemistry, 2021. https://doi.org/10.1039/d1ob00414j.
F. J. Stricker et al., “Facile access to foldable redox-active flavin-peptide conjugates,” Organic & Biomolecular Chemistry, vol. 19, no. 20. Royal Society of Chemistry, pp. 4483–4486, 2021.
Stricker FJ, Kölsch JC, Beil SB, Preiß S, Waldvogel SR, Opatz T, Besenius P. 2021. Facile access to foldable redox-active flavin-peptide conjugates. Organic & Biomolecular Chemistry. 19(20), 4483–4486.
Stricker, Friedrich J., et al. “Facile Access to Foldable Redox-Active Flavin-Peptide Conjugates.” Organic & Biomolecular Chemistry, vol. 19, no. 20, Royal Society of Chemistry, 2021, pp. 4483–86, doi:10.1039/d1ob00414j.

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