Florian Schur
Schur Group
35 Publications
2024 | Journal Article | IST-REx-ID: 14979 |
Datler J, Hansen J, Thader A, et al. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. 2024. doi:10.1038/s41594-023-01201-6
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
2024 | Journal Article | IST-REx-ID: 15146 |
Zens B, Fäßler F, Hansen J, et al. Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. Journal of Cell Biology. 2024;223(6). doi:10.1083/jcb.202309125
[Published Version]
View
| Files available
| DOI
| PubMed | Europe PMC
2023 | Journal Article | IST-REx-ID: 12421 |
Fäßler F, Javoor M, Schur FK. Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM. Biochemical Society Transactions. 2023;51(1):87-99. doi:10.1042/bst20220221
[Published Version]
View
| Files available
| DOI
| WoS
2023 | Journal Article | IST-REx-ID: 12334 |
Fäßler F, Javoor M, Datler J, et al. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. Science Advances. 2023;9(3). doi:10.1126/sciadv.add6495
[Published Version]
View
| Files available
| DOI
| WoS
2023 | Research Data | IST-REx-ID: 14562 |
Schur FK. Research data of the publication “ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning.” 2023. doi:10.15479/AT:ISTA:14562
[Published Version]
View
| Files available
| DOI
2023 | Scientific Software | IST-REx-ID: 14502 |
Dimchev GA, Amiri B, Fäßler F, Falcke M, Schur FK. Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data. 2023. doi:10.15479/AT:ISTA:14502
View
| Files available
| DOI
2023 | Journal Article | IST-REx-ID: 14255 |
Koch J, Xin Q, Obr M, et al. The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells. PLoS Pathogens. 2023;19(8). doi:10.1371/journal.ppat.1011562
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 10639 |
Windhaber S, Xin Q, Uckeley ZM, et al. The Orthobunyavirus Germiston enters host cells from late endosomes. Journal of Virology. 2022;96(5). doi:10.1128/jvi.02146-21
[Published Version]
View
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 11155 |
Obr M, Hagen WJH, Dick RA, Yu L, Kotecha A, Schur FK. Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs. Journal of Structural Biology. 2022;214(2). doi:10.1016/j.jsb.2022.107852
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 11351 |
Nicolas WJ, Fäßler F, Dutka P, Schur FK, Jensen G, Meyerowitz E. Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks. Current Biology. 2022;32(11):P2375-2389. doi:10.1016/j.cub.2022.04.024
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 9431 |
Obr M, Ricana CL, Nikulin N, et al. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23506-0
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 10103 |
Obr M, Schur FK, Dick RA. A structural perspective of the role of IP6 in immature and mature retroviral assembly. Viruses. 2021;13(9). doi:10.3390/v13091853
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 10290 |
Dimchev GA, Amiri B, Fäßler F, Falcke M, Schur FK. Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data. Journal of Structural Biology. 2021;213(4). doi:10.1016/j.jsb.2021.107808
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 9429 |
Morandell J, Schwarz LA, Basilico B, et al. Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23123-x
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Journal Article | IST-REx-ID: 8971 |
Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. Nature Communications. 2020;11. doi:10.1038/s41467-020-20286-x
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Journal Article | IST-REx-ID: 7464 |
Dick RA, Xu C, Morado DR, et al. Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. PLOS Pathogens. 2020;16(1). doi:10.1371/journal.ppat.1008277
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2020 | Research Data | IST-REx-ID: 14592 |
Schur FK. STL-files for 3D-printed grid holders described in Fäßler F, Zens B, et al.; 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy. 2020. doi:10.15479/AT:ISTA:14592
[Published Version]
View
| Files available
| DOI
2020 | Journal Article | IST-REx-ID: 15286
Fäßler F, Dimchev GA, Hodirnau V-V, et al. Cryo-electron tomography workflows for quantitative analysis of actin networks involved in cell migration. Microscopy and Microanalysis. 2020;26(S2):2518-2519. doi:10.1017/s1431927620021881
View
| DOI
2020 | Journal Article | IST-REx-ID: 8586 |
Fäßler F, Zens B, Hauschild R, Schur FK. 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy. Journal of Structural Biology. 2020;212(3). doi:10.1016/j.jsb.2020.107633
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Journal Article | IST-REx-ID: 6343
Schur FK. Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging. Current Opinion in Structural Biology. 2019;58(10):1-9. doi:10.1016/j.sbi.2019.03.018
View
| DOI
| WoS
2019 | Book Chapter | IST-REx-ID: 6890
Obr M, Schur FK. Structural analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging. In: Rey FA, ed. Complementary Strategies to Study Virus Structure and Function. Vol 105. Advances in Virus Research. Elsevier; 2019:117-159. doi:10.1016/bs.aivir.2019.07.008
View
| DOI
| WoS
| PubMed | Europe PMC
2018 | Journal Article | IST-REx-ID: 150 |
Dick R, Zadrozny KK, Xu C, et al. Inositol phosphates are assembly co-factors for HIV-1. Nature. 2018;560(7719):509–512. doi:10.1038/s41586-018-0396-4
[Submitted Version]
View
| Files available
| DOI
| Download Submitted Version (ext.)
| WoS
| PubMed | Europe PMC
2018 | Journal Article | IST-REx-ID: 5770 |
Qu K, Glass B, Doležal M, et al. Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences. 2018;115(50):E11751-E11760. doi:10.1073/pnas.1811580115
[Submitted Version]
View
| DOI
| Download Submitted Version (ext.)
| WoS
| PubMed | Europe PMC
2017 | Journal Article | IST-REx-ID: 817 |
Turoňová B, Schur FK, Wan W, Briggs J. Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4Å. Journal of Structural Biology. 2017;199(3):187-195. doi:10.1016/j.jsb.2017.07.007
[Published Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 5771 |
Mattei S, Schur FK, Briggs JA. Retrovirus maturation—an extraordinary structural transformation. Current Opinion in Virology. 2016;18(6):27-35. doi:10.1016/j.coviro.2016.02.008
[Published Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 813
Füzik T, Píchalová R, Schur FK, et al. Nucleic acid binding by Mason-Pfizer monkey virus CA promotes virus assembly and genome packaging. Journal of Virology. 2016;90(9):4593-4603. doi:10.1128/JVI.03197-15
View
| DOI
2016 | Journal Article | IST-REx-ID: 816
Schur FK, Obr M, Hagen W, et al. An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation. Science. 2016;353(6298):506-508. doi:10.1126/science.aaf9620
View
| DOI
2016 | Journal Article | IST-REx-ID: 1321 |
Leithner AF, Eichner A, Müller J, et al. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology. 2016;18:1253-1259. doi:10.1038/ncb3426
[Submitted Version]
View
| Files available
| DOI
2015 | Journal Article | IST-REx-ID: 815
Schur FK, Dick R, Hagen W, Vogt V, Briggs J. The structure of immature virus like Rous sarcoma virus gag particles reveals a structural role for the p10 domain in assembly. Journal of Virology. 2015;89(20):10294-10302. doi:10.1128/JVI.01502-15
View
| DOI
| PubMed | Europe PMC
2015 | Journal Article | IST-REx-ID: 814
Schur FK, Hagen W, Rumlová M, et al. Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution. Nature. 2015;517(7535):505-508. doi:10.1038/nature13838
View
| DOI
2014 | Journal Article | IST-REx-ID: 809
Bharata T, Menendez L, Hagena W, et al. Cryo electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly. PNAS. 2014;111(22):8233-8238. doi:10.1073/pnas.1401455111
View
| DOI
2013 | Journal Article | IST-REx-ID: 811
Steffen A, Ladwein M, Dimchev GA, et al. Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation. Journal of Cell Science. 2013;126(20):4572-4588. doi:10.1242/jcs.118232
View
| DOI
2013 | Journal Article | IST-REx-ID: 812
Koestler S, Steffen A, Nemethova M, et al. Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin. Molecular Biology of the Cell. 2013;24(18):2861-2875. doi:10.1091/mbc.E12-12-0857
View
| DOI
2013 | Journal Article | IST-REx-ID: 810
Schur FK, Hagen W, De Marco A, Briggs J. Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging. Journal of Structural Biology. 2013;184(3):394-400. doi:10.1016/j.jsb.2013.10.015
View
| DOI
2012 | Journal Article | IST-REx-ID: 808 |
Vinzenz M, Nemethova M, Schur FK, et al. Actin branching in the initiation and maintenance of lamellipodia. Journal of Cell Science. 2012;125(11):2775-2785. doi:10.1242/jcs.107623
View
| Files available
| DOI
35 Publications
2024 | Journal Article | IST-REx-ID: 14979 |
Datler J, Hansen J, Thader A, et al. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. 2024. doi:10.1038/s41594-023-01201-6
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
2024 | Journal Article | IST-REx-ID: 15146 |
Zens B, Fäßler F, Hansen J, et al. Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix. Journal of Cell Biology. 2024;223(6). doi:10.1083/jcb.202309125
[Published Version]
View
| Files available
| DOI
| PubMed | Europe PMC
2023 | Journal Article | IST-REx-ID: 12421 |
Fäßler F, Javoor M, Schur FK. Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM. Biochemical Society Transactions. 2023;51(1):87-99. doi:10.1042/bst20220221
[Published Version]
View
| Files available
| DOI
| WoS
2023 | Journal Article | IST-REx-ID: 12334 |
Fäßler F, Javoor M, Datler J, et al. ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning. Science Advances. 2023;9(3). doi:10.1126/sciadv.add6495
[Published Version]
View
| Files available
| DOI
| WoS
2023 | Research Data | IST-REx-ID: 14562 |
Schur FK. Research data of the publication “ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning.” 2023. doi:10.15479/AT:ISTA:14562
[Published Version]
View
| Files available
| DOI
2023 | Scientific Software | IST-REx-ID: 14502 |
Dimchev GA, Amiri B, Fäßler F, Falcke M, Schur FK. Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data. 2023. doi:10.15479/AT:ISTA:14502
View
| Files available
| DOI
2023 | Journal Article | IST-REx-ID: 14255 |
Koch J, Xin Q, Obr M, et al. The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells. PLoS Pathogens. 2023;19(8). doi:10.1371/journal.ppat.1011562
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 10639 |
Windhaber S, Xin Q, Uckeley ZM, et al. The Orthobunyavirus Germiston enters host cells from late endosomes. Journal of Virology. 2022;96(5). doi:10.1128/jvi.02146-21
[Published Version]
View
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 11155 |
Obr M, Hagen WJH, Dick RA, Yu L, Kotecha A, Schur FK. Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs. Journal of Structural Biology. 2022;214(2). doi:10.1016/j.jsb.2022.107852
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Journal Article | IST-REx-ID: 11351 |
Nicolas WJ, Fäßler F, Dutka P, Schur FK, Jensen G, Meyerowitz E. Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks. Current Biology. 2022;32(11):P2375-2389. doi:10.1016/j.cub.2022.04.024
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 9431 |
Obr M, Ricana CL, Nikulin N, et al. Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23506-0
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 10103 |
Obr M, Schur FK, Dick RA. A structural perspective of the role of IP6 in immature and mature retroviral assembly. Viruses. 2021;13(9). doi:10.3390/v13091853
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2021 | Journal Article | IST-REx-ID: 10290 |
Dimchev GA, Amiri B, Fäßler F, Falcke M, Schur FK. Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data. Journal of Structural Biology. 2021;213(4). doi:10.1016/j.jsb.2021.107808
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Journal Article | IST-REx-ID: 9429 |
Morandell J, Schwarz LA, Basilico B, et al. Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nature Communications. 2021;12(1). doi:10.1038/s41467-021-23123-x
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Journal Article | IST-REx-ID: 8971 |
Fäßler F, Dimchev GA, Hodirnau V-V, Wan W, Schur FK. Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction. Nature Communications. 2020;11. doi:10.1038/s41467-020-20286-x
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Journal Article | IST-REx-ID: 7464 |
Dick RA, Xu C, Morado DR, et al. Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. PLOS Pathogens. 2020;16(1). doi:10.1371/journal.ppat.1008277
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2020 | Research Data | IST-REx-ID: 14592 |
Schur FK. STL-files for 3D-printed grid holders described in Fäßler F, Zens B, et al.; 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy. 2020. doi:10.15479/AT:ISTA:14592
[Published Version]
View
| Files available
| DOI
2020 | Journal Article | IST-REx-ID: 15286
Fäßler F, Dimchev GA, Hodirnau V-V, et al. Cryo-electron tomography workflows for quantitative analysis of actin networks involved in cell migration. Microscopy and Microanalysis. 2020;26(S2):2518-2519. doi:10.1017/s1431927620021881
View
| DOI
2020 | Journal Article | IST-REx-ID: 8586 |
Fäßler F, Zens B, Hauschild R, Schur FK. 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy. Journal of Structural Biology. 2020;212(3). doi:10.1016/j.jsb.2020.107633
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Journal Article | IST-REx-ID: 6343
Schur FK. Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging. Current Opinion in Structural Biology. 2019;58(10):1-9. doi:10.1016/j.sbi.2019.03.018
View
| DOI
| WoS
2019 | Book Chapter | IST-REx-ID: 6890
Obr M, Schur FK. Structural analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging. In: Rey FA, ed. Complementary Strategies to Study Virus Structure and Function. Vol 105. Advances in Virus Research. Elsevier; 2019:117-159. doi:10.1016/bs.aivir.2019.07.008
View
| DOI
| WoS
| PubMed | Europe PMC
2018 | Journal Article | IST-REx-ID: 150 |
Dick R, Zadrozny KK, Xu C, et al. Inositol phosphates are assembly co-factors for HIV-1. Nature. 2018;560(7719):509–512. doi:10.1038/s41586-018-0396-4
[Submitted Version]
View
| Files available
| DOI
| Download Submitted Version (ext.)
| WoS
| PubMed | Europe PMC
2018 | Journal Article | IST-REx-ID: 5770 |
Qu K, Glass B, Doležal M, et al. Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences. 2018;115(50):E11751-E11760. doi:10.1073/pnas.1811580115
[Submitted Version]
View
| DOI
| Download Submitted Version (ext.)
| WoS
| PubMed | Europe PMC
2017 | Journal Article | IST-REx-ID: 817 |
Turoňová B, Schur FK, Wan W, Briggs J. Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4Å. Journal of Structural Biology. 2017;199(3):187-195. doi:10.1016/j.jsb.2017.07.007
[Published Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 5771 |
Mattei S, Schur FK, Briggs JA. Retrovirus maturation—an extraordinary structural transformation. Current Opinion in Virology. 2016;18(6):27-35. doi:10.1016/j.coviro.2016.02.008
[Published Version]
View
| Files available
| DOI
2016 | Journal Article | IST-REx-ID: 813
Füzik T, Píchalová R, Schur FK, et al. Nucleic acid binding by Mason-Pfizer monkey virus CA promotes virus assembly and genome packaging. Journal of Virology. 2016;90(9):4593-4603. doi:10.1128/JVI.03197-15
View
| DOI
2016 | Journal Article | IST-REx-ID: 816
Schur FK, Obr M, Hagen W, et al. An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation. Science. 2016;353(6298):506-508. doi:10.1126/science.aaf9620
View
| DOI
2016 | Journal Article | IST-REx-ID: 1321 |
Leithner AF, Eichner A, Müller J, et al. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology. 2016;18:1253-1259. doi:10.1038/ncb3426
[Submitted Version]
View
| Files available
| DOI
2015 | Journal Article | IST-REx-ID: 815
Schur FK, Dick R, Hagen W, Vogt V, Briggs J. The structure of immature virus like Rous sarcoma virus gag particles reveals a structural role for the p10 domain in assembly. Journal of Virology. 2015;89(20):10294-10302. doi:10.1128/JVI.01502-15
View
| DOI
| PubMed | Europe PMC
2015 | Journal Article | IST-REx-ID: 814
Schur FK, Hagen W, Rumlová M, et al. Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution. Nature. 2015;517(7535):505-508. doi:10.1038/nature13838
View
| DOI
2014 | Journal Article | IST-REx-ID: 809
Bharata T, Menendez L, Hagena W, et al. Cryo electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly. PNAS. 2014;111(22):8233-8238. doi:10.1073/pnas.1401455111
View
| DOI
2013 | Journal Article | IST-REx-ID: 811
Steffen A, Ladwein M, Dimchev GA, et al. Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation. Journal of Cell Science. 2013;126(20):4572-4588. doi:10.1242/jcs.118232
View
| DOI
2013 | Journal Article | IST-REx-ID: 812
Koestler S, Steffen A, Nemethova M, et al. Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin. Molecular Biology of the Cell. 2013;24(18):2861-2875. doi:10.1091/mbc.E12-12-0857
View
| DOI
2013 | Journal Article | IST-REx-ID: 810
Schur FK, Hagen W, De Marco A, Briggs J. Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging. Journal of Structural Biology. 2013;184(3):394-400. doi:10.1016/j.jsb.2013.10.015
View
| DOI
2012 | Journal Article | IST-REx-ID: 808 |
Vinzenz M, Nemethova M, Schur FK, et al. Actin branching in the initiation and maintenance of lamellipodia. Journal of Cell Science. 2012;125(11):2775-2785. doi:10.1242/jcs.107623
View
| Files available
| DOI