Alicia K. Michael

16 Publications

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[16]
2023 | Published | Journal Article | IST-REx-ID: 15148 | OA
Cooperation between bHLH transcription factors and histones for DNA access
Michael AK, Stoos L, Crosby P, Eggers N, Nie XY, Makasheva K, Minnich M, Healy KL, Weiss J, Kempf G, Cavadini S, Kater L, Seebacher J, Vecchia L, Chakraborty D, Isbel L, Grand RS, Andersch F, Fribourgh JL, Schübeler D, Zuber J, Liu AC, Becker PB, Fierz B, Partch CL, Menet JS, Thomä NH. 2023. Cooperation between bHLH transcription factors and histones for DNA access. Nature. 619(7969), 385–393.
[Published Version] View | DOI | Download Published Version (ext.)
 
[15]
2023 | Published | Journal Article | IST-REx-ID: 15149 | OA
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
L. Isbel, M. Iskar, S. Durdu, J. Weiss, R.S. Grand, E. Hietter-Pfeiffer, Z. Kozicka, A.K. Michael, L. Burger, N.H. Thomä, D. Schübeler, Nature Structural & Molecular Biology 30 (2023) 948–957.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2021 | Published | Journal Article | IST-REx-ID: 15150
BANP opens chromatin and activates CpG-island-regulated genes
R.S. Grand, L. Burger, C. Gräwe, A.K. Michael, L. Isbel, D. Hess, L. Hoerner, V. Iesmantavicius, S. Durdu, M. Pregnolato, A.R. Krebs, S.A. Smallwood, N. Thomä, M. Vermeulen, D. Schübeler, Nature 596 (2021) 133–137.
View | DOI
 
[13]
2021 | Published | Journal Article | IST-REx-ID: 15151 | OA
Reading the chromatinized genome
A.K. Michael, N.H. Thomä, Cell 184 (2021) 3599–3611.
[Published Version] View | DOI | Download Published Version (ext.)
 
[12]
2020 | Published | Journal Article | IST-REx-ID: 15152
Mechanisms of OCT4-SOX2 motif readout on nucleosomes
A.K. Michael, R.S. Grand, L. Isbel, S. Cavadini, Z. Kozicka, G. Kempf, R.D. Bunker, A.D. Schenk, A. Graff-Meyer, G.R. Pathare, J. Weiss, S. Matsumoto, L. Burger, D. Schübeler, N.H. Thomä, Science 368 (2020) 1460–1465.
View | DOI
 
[11]
2020 | Published | Journal Article | IST-REx-ID: 15153 | OA
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
J.L. Fribourgh, A. Srivastava, C.R. Sandate, A.K. Michael, P.L. Hsu, C. Rakers, L.T. Nguyen, M.R. Torgrimson, G.C.G. Parico, S. Tripathi, N. Zheng, G.C. Lander, T. Hirota, F. Tama, C.L. Partch, ELife 9 (2020).
[Published Version] View | DOI | Download Published Version (ext.)
 
[10]
2019 | Published | Preprint | IST-REx-ID: 15147 | OA
Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms
J.L. Fribourgh, A. Srivastava, C.R. Sandate, A.K. Michael, P.L. Hsu, C. Rakers, L.T. Nguyen, M.R. Torgrimson, G.C.G. Parico, S. Tripathi, N. Zheng, G.C. Lander, T. Hirota, F. Tama, C.L. Partch, BioRxiv (2019).
View | DOI | Download None (ext.)
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 15154 | OA
Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
J.C. Fong, A. Rogers, A.K. Michael, N.C. Parsley, W.-C. Cornell, Y.-C. Lin, P.K. Singh, R. Hartmann, K. Drescher, E. Vinogradov, L.E. Dietrich, C.L. Partch, F.H. Yildiz, ELife 6 (2017).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 15155 | OA
A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms
C.L. Gustafson, N.C. Parsley, H. Asimgil, H.-W. Lee, C. Ahlbach, A.K. Michael, H. Xu, O.L. Williams, T.L. Davis, A.C. Liu, C.L. Partch, Molecular Cell 66 (2017) 447–457.e7.
[Published Version] View | DOI | Download Published Version (ext.)
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 15156
Structural basis of the day-night transition in a bacterial circadian clock
R. Tseng, N.F. Goularte, A. Chavan, J. Luu, S.E. Cohen, Y.-G. Chang, J. Heisler, S. Li, A.K. Michael, S. Tripathi, S.S. Golden, A. LiWang, C.L. Partch, Science 355 (2017) 1174–1180.
View | DOI
 
[6]
2017 | Published | Journal Article | IST-REx-ID: 15157 | OA
Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1
A.K. Michael, J.L. Fribourgh, Y. Chelliah, C.R. Sandate, G.L. Hura, D. Schneidman-Duhovny, S.M. Tripathi, J.S. Takahashi, C.L. Partch, Proceedings of the National Academy of Sciences 114 (2017) 1560–1565.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2017 | Published | Journal Article | IST-REx-ID: 15158 | OA
Animal cryptochromes: Divergent roles in light perception, circadian timekeeping and beyond
A.K. Michael, J.L. Fribourgh, R.N. Van Gelder, C.L. Partch, Photochemistry and Photobiology 93 (2017) 128–140.
[Published Version] View | DOI | Download Published Version (ext.)
 
[4]
2015 | Published | Journal Article | IST-REx-ID: 15159
Cytosolic BMAL1 moonlights as a translation factor
A.K. Michael, H. Asimgil, C.L. Partch, Trends in Biochemical Sciences 40 (2015) 489–490.
View | DOI
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 15160 | OA
Cancer/Testis antigen PASD1 silences the circadian clock
A.K. Michael, S.L. Harvey, P.J. Sammons, A.P. Anderson, H.M. Kopalle, A.H. Banham, C.L. Partch, Molecular Cell 58 (2015) 743–754.
[Published Version] View | DOI | Download Published Version (ext.)
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 15161 | OA
Stereoselective formation of trisubstituted vinyl boronate esters by the acid-mediated elimination of α-hydroxyboronate esters
W. Guan, A.K. Michael, M.L. McIntosh, L. Koren-Selfridge, J.P. Scott, T.B. Clark, The Journal of Organic Chemistry 79 (2014) 7199–7204.
[Published Version] View | DOI | Download Published Version (ext.)
 
[1]
2013 | Published | Journal Article | IST-REx-ID: 15162
Large-scale cytological profiling for functional analysis of bioactive compounds
M.H. Woehrmann, W.M. Bray, J.K. Durbin, S.C. Nisam, A.K. Michael, E. Glassey, J.M. Stuart, R.S. Lokey, Molecular BioSystems 9 (2013).
View | DOI
 
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1 Grants


Circadian structural transitions of chromatin (ChromaChrono)

2025-01-01 – 2029-12-31
European Research Council

16 Publications

Mark all

[16]
2023 | Published | Journal Article | IST-REx-ID: 15148 | OA
Cooperation between bHLH transcription factors and histones for DNA access
Michael AK, Stoos L, Crosby P, Eggers N, Nie XY, Makasheva K, Minnich M, Healy KL, Weiss J, Kempf G, Cavadini S, Kater L, Seebacher J, Vecchia L, Chakraborty D, Isbel L, Grand RS, Andersch F, Fribourgh JL, Schübeler D, Zuber J, Liu AC, Becker PB, Fierz B, Partch CL, Menet JS, Thomä NH. 2023. Cooperation between bHLH transcription factors and histones for DNA access. Nature. 619(7969), 385–393.
[Published Version] View | DOI | Download Published Version (ext.)
 
[15]
2023 | Published | Journal Article | IST-REx-ID: 15149 | OA
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
L. Isbel, M. Iskar, S. Durdu, J. Weiss, R.S. Grand, E. Hietter-Pfeiffer, Z. Kozicka, A.K. Michael, L. Burger, N.H. Thomä, D. Schübeler, Nature Structural & Molecular Biology 30 (2023) 948–957.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2021 | Published | Journal Article | IST-REx-ID: 15150
BANP opens chromatin and activates CpG-island-regulated genes
R.S. Grand, L. Burger, C. Gräwe, A.K. Michael, L. Isbel, D. Hess, L. Hoerner, V. Iesmantavicius, S. Durdu, M. Pregnolato, A.R. Krebs, S.A. Smallwood, N. Thomä, M. Vermeulen, D. Schübeler, Nature 596 (2021) 133–137.
View | DOI
 
[13]
2021 | Published | Journal Article | IST-REx-ID: 15151 | OA
Reading the chromatinized genome
A.K. Michael, N.H. Thomä, Cell 184 (2021) 3599–3611.
[Published Version] View | DOI | Download Published Version (ext.)
 
[12]
2020 | Published | Journal Article | IST-REx-ID: 15152
Mechanisms of OCT4-SOX2 motif readout on nucleosomes
A.K. Michael, R.S. Grand, L. Isbel, S. Cavadini, Z. Kozicka, G. Kempf, R.D. Bunker, A.D. Schenk, A. Graff-Meyer, G.R. Pathare, J. Weiss, S. Matsumoto, L. Burger, D. Schübeler, N.H. Thomä, Science 368 (2020) 1460–1465.
View | DOI
 
[11]
2020 | Published | Journal Article | IST-REx-ID: 15153 | OA
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
J.L. Fribourgh, A. Srivastava, C.R. Sandate, A.K. Michael, P.L. Hsu, C. Rakers, L.T. Nguyen, M.R. Torgrimson, G.C.G. Parico, S. Tripathi, N. Zheng, G.C. Lander, T. Hirota, F. Tama, C.L. Partch, ELife 9 (2020).
[Published Version] View | DOI | Download Published Version (ext.)
 
[10]
2019 | Published | Preprint | IST-REx-ID: 15147 | OA
Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms
J.L. Fribourgh, A. Srivastava, C.R. Sandate, A.K. Michael, P.L. Hsu, C. Rakers, L.T. Nguyen, M.R. Torgrimson, G.C.G. Parico, S. Tripathi, N. Zheng, G.C. Lander, T. Hirota, F. Tama, C.L. Partch, BioRxiv (2019).
View | DOI | Download None (ext.)
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 15154 | OA
Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
J.C. Fong, A. Rogers, A.K. Michael, N.C. Parsley, W.-C. Cornell, Y.-C. Lin, P.K. Singh, R. Hartmann, K. Drescher, E. Vinogradov, L.E. Dietrich, C.L. Partch, F.H. Yildiz, ELife 6 (2017).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 15155 | OA
A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms
C.L. Gustafson, N.C. Parsley, H. Asimgil, H.-W. Lee, C. Ahlbach, A.K. Michael, H. Xu, O.L. Williams, T.L. Davis, A.C. Liu, C.L. Partch, Molecular Cell 66 (2017) 447–457.e7.
[Published Version] View | DOI | Download Published Version (ext.)
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 15156
Structural basis of the day-night transition in a bacterial circadian clock
R. Tseng, N.F. Goularte, A. Chavan, J. Luu, S.E. Cohen, Y.-G. Chang, J. Heisler, S. Li, A.K. Michael, S. Tripathi, S.S. Golden, A. LiWang, C.L. Partch, Science 355 (2017) 1174–1180.
View | DOI
 
[6]
2017 | Published | Journal Article | IST-REx-ID: 15157 | OA
Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1
A.K. Michael, J.L. Fribourgh, Y. Chelliah, C.R. Sandate, G.L. Hura, D. Schneidman-Duhovny, S.M. Tripathi, J.S. Takahashi, C.L. Partch, Proceedings of the National Academy of Sciences 114 (2017) 1560–1565.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2017 | Published | Journal Article | IST-REx-ID: 15158 | OA
Animal cryptochromes: Divergent roles in light perception, circadian timekeeping and beyond
A.K. Michael, J.L. Fribourgh, R.N. Van Gelder, C.L. Partch, Photochemistry and Photobiology 93 (2017) 128–140.
[Published Version] View | DOI | Download Published Version (ext.)
 
[4]
2015 | Published | Journal Article | IST-REx-ID: 15159
Cytosolic BMAL1 moonlights as a translation factor
A.K. Michael, H. Asimgil, C.L. Partch, Trends in Biochemical Sciences 40 (2015) 489–490.
View | DOI
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 15160 | OA
Cancer/Testis antigen PASD1 silences the circadian clock
A.K. Michael, S.L. Harvey, P.J. Sammons, A.P. Anderson, H.M. Kopalle, A.H. Banham, C.L. Partch, Molecular Cell 58 (2015) 743–754.
[Published Version] View | DOI | Download Published Version (ext.)
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 15161 | OA
Stereoselective formation of trisubstituted vinyl boronate esters by the acid-mediated elimination of α-hydroxyboronate esters
W. Guan, A.K. Michael, M.L. McIntosh, L. Koren-Selfridge, J.P. Scott, T.B. Clark, The Journal of Organic Chemistry 79 (2014) 7199–7204.
[Published Version] View | DOI | Download Published Version (ext.)
 
[1]
2013 | Published | Journal Article | IST-REx-ID: 15162
Large-scale cytological profiling for functional analysis of bioactive compounds
M.H. Woehrmann, W.M. Bray, J.K. Durbin, S.C. Nisam, A.K. Michael, E. Glassey, J.M. Stuart, R.S. Lokey, Molecular BioSystems 9 (2013).
View | DOI
 
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  • 11 OA Fulltext(s)

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