Alicia K. Michael

19 Publications

Mark all

[19]
2025 | Published | Journal Article | IST-REx-ID: 20374 | OA | PlanS
Chakraborty D, Sandate CR, Isbel L, et al. Nucleosomes specify co-factor access to p53. Molecular Cell. 2025;85(15):2919-2936.e12. doi:10.1016/j.molcel.2025.06.027
[Published Version] View | Files available | DOI
 
[18]
2025 | In Press | Journal Article | IST-REx-ID: 20935 | OA | PlanS
Kelley R, Khavnekar S, Righetto RD, Heebner J, Obr M, Zhang X, Chakraborty S, Tagiltsev G, Michael AK, Van Dorst S, Waltz F, Mccafferty CL, Lamm L, Zufferey S, Van Der Stappen P, Van Den Hoek H, Wietrzynski W, Harar P, Wan W, Briggs JAG, Plitzko JM, Engel BD, Kotecha A. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell.
[Published Version] View | DOI | Download Published Version (ext.)
 
[17]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 20924 | OA | PlanS
Kobayashi W, Michael AK, Ruangroengkulrith S, Kümmecke M, Tachibana K. Protocol for integrative analysis of transcription factor-nucleosome interactions using SeEN-seq and cryo-EM structure determination. STAR Protocols. 2025;7. doi:10.1016/j.xpro.2025.104295
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[16]
2023 | Published | Journal Article | IST-REx-ID: 15148 | OA
Michael AK, Stoos L, Crosby P, Eggers N, Nie XY, Makasheva K, Minnich M, Healy KL, Weiss J, Kempf G, Cavadini S, Kater L, Seebacher J, Vecchia L, Chakraborty D, Isbel L, Grand RS, Andersch F, Fribourgh JL, Schübeler D, Zuber J, Liu AC, Becker PB, Fierz B, Partch CL, Menet JS, Thomä NH. 2023. Cooperation between bHLH transcription factors and histones for DNA access. Nature. 619(7969), 385–393.
[Published Version] View | DOI | Download Published Version (ext.)
 
[15]
2023 | Published | Journal Article | IST-REx-ID: 15149 | OA
Isbel L, Iskar M, Durdu S, et al. Readout of histone methylation by Trim24 locally restricts chromatin opening by p53. Nature Structural & Molecular Biology. 2023;30(7):948-957. doi:10.1038/s41594-023-01021-8
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2021 | Published | Journal Article | IST-REx-ID: 15150
Grand RS, Burger L, Gräwe C, et al. BANP opens chromatin and activates CpG-island-regulated genes. Nature. 2021;596:133-137. doi:10.1038/s41586-021-03689-8
View | DOI
 
[13]
2021 | Published | Journal Article | IST-REx-ID: 15151 | OA
Michael AK, Thomä NH. Reading the chromatinized genome. Cell. 2021;184(14):3599-3611. doi:10.1016/j.cell.2021.05.029
[Published Version] View | DOI | Download Published Version (ext.)
 
[12]
2020 | Published | Journal Article | IST-REx-ID: 15152
Michael AK, Grand RS, Isbel L, et al. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science. 2020;368(6498):1460-1465. doi:10.1126/science.abb0074
View | DOI
 
[11]
2020 | Published | Journal Article | IST-REx-ID: 15153 | OA
Fribourgh JL, Srivastava A, Sandate CR, et al. Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. eLife. 2020;9. doi:10.7554/elife.55275
[Published Version] View | DOI | Download Published Version (ext.)
 
[10]
2019 | Published | Preprint | IST-REx-ID: 15147 | OA
Fribourgh JL, Srivastava A, Sandate CR, et al. Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms. bioRxiv. 2019. doi:10.1101/740464
[Preprint] View | DOI | Download Preprint (ext.)
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 15154 | OA
Fong JC, Rogers A, Michael AK, et al. Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms. eLife. 2017;6. doi:10.7554/elife.26163
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 15155 | OA
Gustafson CL, Parsley NC, Asimgil H, et al. A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms. Molecular Cell. 2017;66(4):447-457.e7. doi:10.1016/j.molcel.2017.04.011
[Published Version] View | DOI | Download Published Version (ext.)
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 15156
Tseng R, Goularte NF, Chavan A, et al. Structural basis of the day-night transition in a bacterial circadian clock. Science. 2017;355(6330):1174-1180. doi:10.1126/science.aag2516
View | DOI
 
[6]
2017 | Published | Journal Article | IST-REx-ID: 15157 | OA
Michael AK, Fribourgh JL, Chelliah Y, et al. Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1. Proceedings of the National Academy of Sciences. 2017;114(7):1560-1565. doi:10.1073/pnas.1615310114
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2017 | Published | Journal Article | IST-REx-ID: 15158 | OA
Michael AK, Fribourgh JL, Van Gelder RN, Partch CL. Animal cryptochromes: Divergent roles in light perception, circadian timekeeping and beyond. Photochemistry and Photobiology. 2017;93(1):128-140. doi:10.1111/php.12677
[Published Version] View | DOI | Download Published Version (ext.)
 
[4]
2015 | Published | Journal Article | IST-REx-ID: 15159
Michael AK, Asimgil H, Partch CL. Cytosolic BMAL1 moonlights as a translation factor. Trends in Biochemical Sciences. 2015;40(9):489-490. doi:10.1016/j.tibs.2015.07.006
View | DOI
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 15160 | OA
Michael AK, Harvey SL, Sammons PJ, et al. Cancer/Testis antigen PASD1 silences the circadian clock. Molecular Cell. 2015;58(5):743-754. doi:10.1016/j.molcel.2015.03.031
[Published Version] View | DOI | Download Published Version (ext.)
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 15161 | OA
Guan W, Michael AK, McIntosh ML, Koren-Selfridge L, Scott JP, Clark TB. Stereoselective formation of trisubstituted vinyl boronate esters by the acid-mediated elimination of α-hydroxyboronate esters. The Journal of Organic Chemistry. 2014;79(15):7199-7204. doi:10.1021/jo500773t
[Published Version] View | DOI | Download Published Version (ext.)
 
[1]
2013 | Published | Journal Article | IST-REx-ID: 15162
Woehrmann MH, Bray WM, Durbin JK, et al. Large-scale cytological profiling for functional analysis of bioactive compounds. Molecular BioSystems. 2013;9(11). doi:10.1039/c3mb70245f
View | DOI
 
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19 Publications

Mark all

[19]
2025 | Published | Journal Article | IST-REx-ID: 20374 | OA | PlanS
Chakraborty D, Sandate CR, Isbel L, et al. Nucleosomes specify co-factor access to p53. Molecular Cell. 2025;85(15):2919-2936.e12. doi:10.1016/j.molcel.2025.06.027
[Published Version] View | Files available | DOI
 
[18]
2025 | In Press | Journal Article | IST-REx-ID: 20935 | OA | PlanS
Kelley R, Khavnekar S, Righetto RD, Heebner J, Obr M, Zhang X, Chakraborty S, Tagiltsev G, Michael AK, Van Dorst S, Waltz F, Mccafferty CL, Lamm L, Zufferey S, Van Der Stappen P, Van Den Hoek H, Wietrzynski W, Harar P, Wan W, Briggs JAG, Plitzko JM, Engel BD, Kotecha A. Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii. Molecular Cell.
[Published Version] View | DOI | Download Published Version (ext.)
 
[17]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 20924 | OA | PlanS
Kobayashi W, Michael AK, Ruangroengkulrith S, Kümmecke M, Tachibana K. Protocol for integrative analysis of transcription factor-nucleosome interactions using SeEN-seq and cryo-EM structure determination. STAR Protocols. 2025;7. doi:10.1016/j.xpro.2025.104295
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[16]
2023 | Published | Journal Article | IST-REx-ID: 15148 | OA
Michael AK, Stoos L, Crosby P, Eggers N, Nie XY, Makasheva K, Minnich M, Healy KL, Weiss J, Kempf G, Cavadini S, Kater L, Seebacher J, Vecchia L, Chakraborty D, Isbel L, Grand RS, Andersch F, Fribourgh JL, Schübeler D, Zuber J, Liu AC, Becker PB, Fierz B, Partch CL, Menet JS, Thomä NH. 2023. Cooperation between bHLH transcription factors and histones for DNA access. Nature. 619(7969), 385–393.
[Published Version] View | DOI | Download Published Version (ext.)
 
[15]
2023 | Published | Journal Article | IST-REx-ID: 15149 | OA
Isbel L, Iskar M, Durdu S, et al. Readout of histone methylation by Trim24 locally restricts chromatin opening by p53. Nature Structural & Molecular Biology. 2023;30(7):948-957. doi:10.1038/s41594-023-01021-8
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2021 | Published | Journal Article | IST-REx-ID: 15150
Grand RS, Burger L, Gräwe C, et al. BANP opens chromatin and activates CpG-island-regulated genes. Nature. 2021;596:133-137. doi:10.1038/s41586-021-03689-8
View | DOI
 
[13]
2021 | Published | Journal Article | IST-REx-ID: 15151 | OA
Michael AK, Thomä NH. Reading the chromatinized genome. Cell. 2021;184(14):3599-3611. doi:10.1016/j.cell.2021.05.029
[Published Version] View | DOI | Download Published Version (ext.)
 
[12]
2020 | Published | Journal Article | IST-REx-ID: 15152
Michael AK, Grand RS, Isbel L, et al. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science. 2020;368(6498):1460-1465. doi:10.1126/science.abb0074
View | DOI
 
[11]
2020 | Published | Journal Article | IST-REx-ID: 15153 | OA
Fribourgh JL, Srivastava A, Sandate CR, et al. Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. eLife. 2020;9. doi:10.7554/elife.55275
[Published Version] View | DOI | Download Published Version (ext.)
 
[10]
2019 | Published | Preprint | IST-REx-ID: 15147 | OA
Fribourgh JL, Srivastava A, Sandate CR, et al. Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms. bioRxiv. 2019. doi:10.1101/740464
[Preprint] View | DOI | Download Preprint (ext.)
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 15154 | OA
Fong JC, Rogers A, Michael AK, et al. Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms. eLife. 2017;6. doi:10.7554/elife.26163
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 15155 | OA
Gustafson CL, Parsley NC, Asimgil H, et al. A slow conformational switch in the BMAL1 transactivation domain modulates circadian rhythms. Molecular Cell. 2017;66(4):447-457.e7. doi:10.1016/j.molcel.2017.04.011
[Published Version] View | DOI | Download Published Version (ext.)
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 15156
Tseng R, Goularte NF, Chavan A, et al. Structural basis of the day-night transition in a bacterial circadian clock. Science. 2017;355(6330):1174-1180. doi:10.1126/science.aag2516
View | DOI
 
[6]
2017 | Published | Journal Article | IST-REx-ID: 15157 | OA
Michael AK, Fribourgh JL, Chelliah Y, et al. Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1. Proceedings of the National Academy of Sciences. 2017;114(7):1560-1565. doi:10.1073/pnas.1615310114
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2017 | Published | Journal Article | IST-REx-ID: 15158 | OA
Michael AK, Fribourgh JL, Van Gelder RN, Partch CL. Animal cryptochromes: Divergent roles in light perception, circadian timekeeping and beyond. Photochemistry and Photobiology. 2017;93(1):128-140. doi:10.1111/php.12677
[Published Version] View | DOI | Download Published Version (ext.)
 
[4]
2015 | Published | Journal Article | IST-REx-ID: 15159
Michael AK, Asimgil H, Partch CL. Cytosolic BMAL1 moonlights as a translation factor. Trends in Biochemical Sciences. 2015;40(9):489-490. doi:10.1016/j.tibs.2015.07.006
View | DOI
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 15160 | OA
Michael AK, Harvey SL, Sammons PJ, et al. Cancer/Testis antigen PASD1 silences the circadian clock. Molecular Cell. 2015;58(5):743-754. doi:10.1016/j.molcel.2015.03.031
[Published Version] View | DOI | Download Published Version (ext.)
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 15161 | OA
Guan W, Michael AK, McIntosh ML, Koren-Selfridge L, Scott JP, Clark TB. Stereoselective formation of trisubstituted vinyl boronate esters by the acid-mediated elimination of α-hydroxyboronate esters. The Journal of Organic Chemistry. 2014;79(15):7199-7204. doi:10.1021/jo500773t
[Published Version] View | DOI | Download Published Version (ext.)
 
[1]
2013 | Published | Journal Article | IST-REx-ID: 15162
Woehrmann MH, Bray WM, Durbin JK, et al. Large-scale cytological profiling for functional analysis of bioactive compounds. Molecular BioSystems. 2013;9(11). doi:10.1039/c3mb70245f
View | DOI
 
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