Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos

Project Period: 2024-05-01 – 2030-04-30
Funder: European Research Council
Acronym
DynaTrans
Principal Investigator
Department(s)
Tkacik Group
Grant Number
101118866
Grant DOI
10.3030/101118866
Funder
European Research Council
Funder Schema
HE-ERC-SyG
Funder Registry
10.13039/501100000781

4 Publications

2026 | Published | Journal Article | IST-REx-ID: 21282 | OA | PlanS
Marr's three levels for embryonic development: Information, dynamical systems, gene networks
D. Brückner, G. Tkačik, PRX Life 4 (2026).
[Published Version] View | Files available | DOI | arXiv
 
2025 | Published | Journal Article | IST-REx-ID: 18849 | OA
Deriving a genetic regulatory network from an optimization principle
T.R. Sokolowski, T. Gregor, W. Bialek, G. Tkačik, Proceedings of the National Academy of Sciences 122 (2025).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2025 | Published | Journal Article | IST-REx-ID: 18850 | OA
Chromatin enables precise and scalable gene regulation with factors of limited specificity
M.L. Perkins, J. Crocker, G. Tkačik, Proceedings of the National Academy of Sciences 122 (2025).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2025 | Published | Journal Article | IST-REx-ID: 19701 | OA
Information processing in biochemical networks
G. Tkačik, P.R.T. Wolde, Annual Review of Biophysics 54 (2025) 249–274.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

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