Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos

Project Period: 2024-05-01 – 2030-04-30

Funder: European Research Council

Acronym

DynaTrans

Principal Investigator

Department(s)

Tkacik Group

Grant Number

101118866

Grant DOI

Funder

European Research Council

Funder Schema

HE-ERC-SyG

Funder Registry

[Published Version] View | Files available | DOI | arXiv

Nonlocal decoding of positional and correlational information during development
C.Y. Zhang, P. Mateu Hoyos, D. Brückner, G. Tkačik, Physical Review Letters 137 (2026).

[Published Version] View | Files available | DOI

2026 | Published | Journal Article | IST-REx-ID: 22363 |

Invariant nonequilibrium dynamics in gene regulation optimize information flow
B. Zoller, A. Benichou, T. Gregor, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 123 (2026).

[Published Version] View | Files available | DOI | PubMed | Europe PMC

2025 | Published | Journal Article | IST-REx-ID: 18849 |

Deriving a genetic regulatory network from an optimization principle
T.R. Sokolowski, T. Gregor, W. Bialek, G. Tkačik, Proceedings of the National Academy of Sciences 122 (2025).

2025 | Published | Journal Article | IST-REx-ID: 18850 |

Chromatin enables precise and scalable gene regulation with factors of limited specificity
M.L. Perkins, J. Crocker, G. Tkačik, Proceedings of the National Academy of Sciences 122 (2025).

2025 | Published | Journal Article | IST-REx-ID: 19701 |

Information processing in biochemical networks
G. Tkačik, P.R.T. Wolde, Annual Review of Biophysics 54 (2025) 249–274.