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133 Publications
2022 | Published | Journal Article | IST-REx-ID: 10939 | 
Parameter inference for stochastic biochemical models from perturbation experiments parallelised at the single cell level
A. Davidović, R.P. Chait, G. Batt, J. Ruess, PLoS Computational Biology 18 (2022).
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A. Davidović, R.P. Chait, G. Batt, J. Ruess, PLoS Computational Biology 18 (2022).
2021 | Published | Journal Article | IST-REx-ID: 15270 |
Active efflux leads to heterogeneous dissipation of proton motive force by protonophores in bacteria
D. Le, E. Krasnopeeva, F. Sinjab, T. Pilizota, M. Kim, MBio 12 (2021).
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D. Le, E. Krasnopeeva, F. Sinjab, T. Pilizota, M. Kim, MBio 12 (2021).
2021 | Published | Journal Article | IST-REx-ID: 10363 |
Rational engineering of an erythropoietin fusion protein to treat hypoxia
J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021).
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J. Lee, A. Vernet, N. Gruber, K.M. Kready, D.R. Burrill, J.C. Way, P.A. Silver, Protein Engineering, Design and Selection 34 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9746 |
High potency of sequential therapy with only beta-lactam antibiotics
A. Batra, R. Römhild, E. Rousseau, S. Franzenburg, S. Niemann, H. Schulenburg, ELife 10 (2021).
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A. Batra, R. Römhild, E. Rousseau, S. Franzenburg, S. Niemann, H. Schulenburg, ELife 10 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9647 |
Long lived transients in gene regulation
T. Petrov, C. Igler, A. Sezgin, T.A. Henzinger, C.C. Guet, Theoretical Computer Science 893 (2021) 1–16.
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T. Petrov, C. Igler, A. Sezgin, T.A. Henzinger, C.C. Guet, Theoretical Computer Science 893 (2021) 1–16.
2021 | Published | Journal Article | IST-REx-ID: 9283 |
Local genetic context shapes the function of a gene regulatory network
A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).
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A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic, T. Paixão, C.C. Guet, ELife 10 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9046 |
Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
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R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9822 |
Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
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T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
2021 | Published | Thesis | IST-REx-ID: 10307 |
Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
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K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, Institute of Science and Technology Austria, 2021.
2021 | Draft | Preprint | IST-REx-ID: 10316 |
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
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K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
2020 | Published | Preprint | IST-REx-ID: 7675 |
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
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R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
2020 | Research Data | IST-REx-ID: 8951 |
Sequences of gene regulatory network permutations for the article "Local genetic context shapes the function of a gene regulatory network"
A.A. Nagy-Staron, (2020).
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A.A. Nagy-Staron, (2020).
2020 | Published | Book Chapter | IST-REx-ID: 8173
Design and application of light-regulated receptor tyrosine kinases
S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
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S. Kainrath, H.L. Janovjak, in:, D. Niopek (Ed.), Photoswitching Proteins, Springer Nature, 2020, pp. 233–246.
2020 | Published | Thesis | IST-REx-ID: 8155 |
Gene regulation across scales – how biophysical constraints shape evolution
R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, Institute of Science and Technology Austria, 2020.
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R. Grah, Gene Regulation across Scales – How Biophysical Constraints Shape Evolution, Institute of Science and Technology Austria, 2020.
2020 | Research Data | IST-REx-ID: 7383 |
Matlab scripts for the Paper: Gene Amplification as a Form of Population-Level Gene Expression regulation
R. Grah, (2020).
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R. Grah, (2020).
2020 | Published | Journal Article | IST-REx-ID: 7569 |
The relation between crosstalk and gene regulation form revisited
R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
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R. Grah, T. Friedlander, PLOS Computational Biology 16 (2020).
2020 | Published | Journal Article | IST-REx-ID: 7652 |
Gene amplification as a form of population-level gene expression regulation
I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
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I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik, C.C. Guet, Nature Ecology & Evolution 4 (2020) 612–625.
2020 | Published | Thesis | IST-REx-ID: 8653 |
The evolution of gene expression by copy number and point mutations
I. Tomanek, The Evolution of Gene Expression by Copy Number and Point Mutations, Institute of Science and Technology Austria, 2020.
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I. Tomanek, The Evolution of Gene Expression by Copy Number and Point Mutations, Institute of Science and Technology Austria, 2020.
2020 | Published | Thesis | IST-REx-ID: 7680 |
Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals
S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, Institute of Science and Technology Austria, 2020.
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S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition of Cellular Signals, Institute of Science and Technology Austria, 2020.
2019 | Published | Journal Article | IST-REx-ID: 6465 |
A modular degron library for synthetic circuits in mammalian cells
H. Chassin, M. Müller, M. Tigges, L. Scheller, M. Lang, M. Fussenegger, Nature Communications 10 (2019).
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H. Chassin, M. Müller, M. Tigges, L. Scheller, M. Lang, M. Fussenegger, Nature Communications 10 (2019).