Carrie Bernecky
Bernecky Group
14 Publications
2023 | Preprint | IST-REx-ID: 14644 |
Mechanism of mammalian transcriptional repression by noncoding RNA
K. Tluckova, A.P. Testa Salmazo, C. Bernecky, (n.d.).
[Submitted Version]
View
| Files available
| DOI
K. Tluckova, A.P. Testa Salmazo, C. Bernecky, (n.d.).
2022 | Journal Article | IST-REx-ID: 12051 |
The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
J.L. Daiß, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F.B. Heiss, G. Abascal-Palacios, E.P. Ramsay, K. Tluckova, J.-C. Mars, T. Fürtges, A. Bruckmann, T. Rudack, C. Bernecky, V. Lamour, K. Panov, A. Vannini, T. Moss, C. Engel, Life Science Alliance 5 (2022).
[Published Version]
View
| Files available
| DOI
| WoS
J.L. Daiß, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F.B. Heiss, G. Abascal-Palacios, E.P. Ramsay, K. Tluckova, J.-C. Mars, T. Fürtges, A. Bruckmann, T. Rudack, C. Bernecky, V. Lamour, K. Panov, A. Vannini, T. Moss, C. Engel, Life Science Alliance 5 (2022).
2022 | Journal Article | IST-REx-ID: 12143 |
Structural and functional basis of mammalian microRNA biogenesis by Dicer
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O’Carroll D, Stefl R, Svoboda P. 2022. Structural and functional basis of mammalian microRNA biogenesis by Dicer. Molecular Cell. 82(21), 4064–4079.e13.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O’Carroll D, Stefl R, Svoboda P. 2022. Structural and functional basis of mammalian microRNA biogenesis by Dicer. Molecular Cell. 82(21), 4064–4079.e13.
2021 | Journal Article | IST-REx-ID: 10163 |
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.
[Published Version]
View
| Files available
| DOI
| WoS
Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.
2017 | Journal Article | IST-REx-ID: 600
Structural basis of RNA polymerase I transcription initiation
C. Engel, T. Gubbey, S. Neyer, S. Sainsbury, C. Oberthuer, C. Baejen, C. Bernecky, P. Cramer, Cell 169 (2017) 120–131.e22.
View
| DOI
C. Engel, T. Gubbey, S. Neyer, S. Sainsbury, C. Oberthuer, C. Baejen, C. Bernecky, P. Cramer, Cell 169 (2017) 120–131.e22.
2017 | Journal Article | IST-REx-ID: 601 |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
Y. Xu, C. Bernecky, C. Lee, K. Maier, B. Schwalb, D. Tegunov, J. Plitzko, H. Urlaub, P. Cramer, Nature Communications 8 (2017).
[Published Version]
View
| Files available
| DOI
Y. Xu, C. Bernecky, C. Lee, K. Maier, B. Schwalb, D. Tegunov, J. Plitzko, H. Urlaub, P. Cramer, Nature Communications 8 (2017).
2017 | Journal Article | IST-REx-ID: 603
Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp
C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology 24 (2017) 809–815.
View
| DOI
C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology 24 (2017) 809–815.
2016 | Journal Article | IST-REx-ID: 602
Structure of transcribing mammalian RNA polymerase II
C. Bernecky, F. Herzog, W. Baumeister, J. Plitzko, P. Cramer, Nature 529 (2016) 551–554.
View
| DOI
C. Bernecky, F. Herzog, W. Baumeister, J. Plitzko, P. Cramer, Nature 529 (2016) 551–554.
2015 | Journal Article | IST-REx-ID: 594
Structural basis of transcription initiation by RNA polymerase II
S. Sainsbury, C. Bernecky, P. Cramer, Nature Reviews Molecular Cell Biology 16 (2015) 129–143.
View
| DOI
S. Sainsbury, C. Bernecky, P. Cramer, Nature Reviews Molecular Cell Biology 16 (2015) 129–143.
2013 | Journal Article | IST-REx-ID: 595 |
Struggling to let go: A non-coding RNA directs its own extension and destruction
C. Bernecky, P. Cramer, EMBO Journal 32 (2013) 771–772.
View
| DOI
| Download None (ext.)
C. Bernecky, P. Cramer, EMBO Journal 32 (2013) 771–772.
2012 | Journal Article | IST-REx-ID: 596 |
Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly
C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
View
| DOI
| Download None (ext.)
C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
2011 | Journal Article | IST-REx-ID: 597
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly
C. Bernecky, P. Grob, C. Ebmeier, E. Nogales, D. Taatjes, PLoS Biology 9 (2011).
View
| DOI
C. Bernecky, P. Grob, C. Ebmeier, E. Nogales, D. Taatjes, PLoS Biology 9 (2011).
2010 | Journal Article | IST-REx-ID: 598 |
P53 activates transcription by directing structural shifts in Mediator
K. Meyer, S. Lin, C. Bernecky, Y. Gao, D. Taatjes, Nature Structural and Molecular Biology 17 (2010) 753–760.
View
| DOI
| Download None (ext.)
K. Meyer, S. Lin, C. Bernecky, Y. Gao, D. Taatjes, Nature Structural and Molecular Biology 17 (2010) 753–760.
2009 | Journal Article | IST-REx-ID: 599 |
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
M. Knuesel, K. Meyer, C. Bernecky, D. Taatjes, Genes and Development 23 (2009) 439–451.
View
| DOI
| Download None (ext.)
M. Knuesel, K. Meyer, C. Bernecky, D. Taatjes, Genes and Development 23 (2009) 439–451.
14 Publications
2023 | Preprint | IST-REx-ID: 14644 |
Mechanism of mammalian transcriptional repression by noncoding RNA
K. Tluckova, A.P. Testa Salmazo, C. Bernecky, (n.d.).
[Submitted Version]
View
| Files available
| DOI
K. Tluckova, A.P. Testa Salmazo, C. Bernecky, (n.d.).
2022 | Journal Article | IST-REx-ID: 12051 |
The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans
J.L. Daiß, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F.B. Heiss, G. Abascal-Palacios, E.P. Ramsay, K. Tluckova, J.-C. Mars, T. Fürtges, A. Bruckmann, T. Rudack, C. Bernecky, V. Lamour, K. Panov, A. Vannini, T. Moss, C. Engel, Life Science Alliance 5 (2022).
[Published Version]
View
| Files available
| DOI
| WoS
J.L. Daiß, M. Pilsl, K. Straub, A. Bleckmann, M. Höcherl, F.B. Heiss, G. Abascal-Palacios, E.P. Ramsay, K. Tluckova, J.-C. Mars, T. Fürtges, A. Bruckmann, T. Rudack, C. Bernecky, V. Lamour, K. Panov, A. Vannini, T. Moss, C. Engel, Life Science Alliance 5 (2022).
2022 | Journal Article | IST-REx-ID: 12143 |
Structural and functional basis of mammalian microRNA biogenesis by Dicer
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O’Carroll D, Stefl R, Svoboda P. 2022. Structural and functional basis of mammalian microRNA biogenesis by Dicer. Molecular Cell. 82(21), 4064–4079.e13.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O’Carroll D, Stefl R, Svoboda P. 2022. Structural and functional basis of mammalian microRNA biogenesis by Dicer. Molecular Cell. 82(21), 4064–4079.e13.
2021 | Journal Article | IST-REx-ID: 10163 |
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.
[Published Version]
View
| Files available
| DOI
| WoS
Appel L-M, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. 2021. PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC. Nature Communications. 12(1), 6078.
2017 | Journal Article | IST-REx-ID: 600
Structural basis of RNA polymerase I transcription initiation
C. Engel, T. Gubbey, S. Neyer, S. Sainsbury, C. Oberthuer, C. Baejen, C. Bernecky, P. Cramer, Cell 169 (2017) 120–131.e22.
View
| DOI
C. Engel, T. Gubbey, S. Neyer, S. Sainsbury, C. Oberthuer, C. Baejen, C. Bernecky, P. Cramer, Cell 169 (2017) 120–131.e22.
2017 | Journal Article | IST-REx-ID: 601 |
Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex
Y. Xu, C. Bernecky, C. Lee, K. Maier, B. Schwalb, D. Tegunov, J. Plitzko, H. Urlaub, P. Cramer, Nature Communications 8 (2017).
[Published Version]
View
| Files available
| DOI
Y. Xu, C. Bernecky, C. Lee, K. Maier, B. Schwalb, D. Tegunov, J. Plitzko, H. Urlaub, P. Cramer, Nature Communications 8 (2017).
2017 | Journal Article | IST-REx-ID: 603
Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp
C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology 24 (2017) 809–815.
View
| DOI
C. Bernecky, J. Plitzko, P. Cramer, Nature Structural and Molecular Biology 24 (2017) 809–815.
2016 | Journal Article | IST-REx-ID: 602
Structure of transcribing mammalian RNA polymerase II
C. Bernecky, F. Herzog, W. Baumeister, J. Plitzko, P. Cramer, Nature 529 (2016) 551–554.
View
| DOI
C. Bernecky, F. Herzog, W. Baumeister, J. Plitzko, P. Cramer, Nature 529 (2016) 551–554.
2015 | Journal Article | IST-REx-ID: 594
Structural basis of transcription initiation by RNA polymerase II
S. Sainsbury, C. Bernecky, P. Cramer, Nature Reviews Molecular Cell Biology 16 (2015) 129–143.
View
| DOI
S. Sainsbury, C. Bernecky, P. Cramer, Nature Reviews Molecular Cell Biology 16 (2015) 129–143.
2013 | Journal Article | IST-REx-ID: 595 |
Struggling to let go: A non-coding RNA directs its own extension and destruction
C. Bernecky, P. Cramer, EMBO Journal 32 (2013) 771–772.
View
| DOI
| Download None (ext.)
C. Bernecky, P. Cramer, EMBO Journal 32 (2013) 771–772.
2012 | Journal Article | IST-REx-ID: 596 |
Activator-mediator binding stabilizes RNA polymerase II orientation within the human mediator-RNA polymerase II-TFIIF assembly
C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
View
| DOI
| Download None (ext.)
C. Bernecky, D. Taatjes, Journal of Molecular Biology 417 (2012) 387–394.
2011 | Journal Article | IST-REx-ID: 597
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly
C. Bernecky, P. Grob, C. Ebmeier, E. Nogales, D. Taatjes, PLoS Biology 9 (2011).
View
| DOI
C. Bernecky, P. Grob, C. Ebmeier, E. Nogales, D. Taatjes, PLoS Biology 9 (2011).
2010 | Journal Article | IST-REx-ID: 598 |
P53 activates transcription by directing structural shifts in Mediator
K. Meyer, S. Lin, C. Bernecky, Y. Gao, D. Taatjes, Nature Structural and Molecular Biology 17 (2010) 753–760.
View
| DOI
| Download None (ext.)
K. Meyer, S. Lin, C. Bernecky, Y. Gao, D. Taatjes, Nature Structural and Molecular Biology 17 (2010) 753–760.
2009 | Journal Article | IST-REx-ID: 599 |
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
M. Knuesel, K. Meyer, C. Bernecky, D. Taatjes, Genes and Development 23 (2009) 439–451.
View
| DOI
| Download None (ext.)
M. Knuesel, K. Meyer, C. Bernecky, D. Taatjes, Genes and Development 23 (2009) 439–451.