Florian Schur

41 Publications

Mark all

[41]
2026 | Epub ahead of print | Journal Article | IST-REx-ID: 22372 | OA | PlanS
An intrinsic cytoskeletal oscillator establishes neuronal polarity
T.C. Lin, C.H. Coles, E. Alfadil, F. Fäßler, A. Husch, S. Dupraz, T. Pietralla, A. Narita, M. Schelski, K.C. Flynn, S. Stern, C. Möhl, B.J. Hilton, F. Vauti, H.H. Arnold, F.K. Schur, F. Bradke, Nature (2026).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[40]
2026 | Epub ahead of print | Journal Article | IST-REx-ID: 22403 | OA | PlanS
Gap‐free information transfer in 4D‐STEM via fusion of complementary scattering channels
S. You, G. Varnavides, S. Khavnekar, N. Palatkin, S. Shao, M. Wu, D. Stroppa, D. Chernikova, B. Zhu, R. Egoavil, S. Vespucci, D. Krishnan, X. Ye, F.K. Schur, E. Spiecker, P. Pelz, Advanced Science (2026).
[Published Version] View | DOI | Download Published Version (ext.) | arXiv
 
[39]
2026 | Published | Journal Article | IST-REx-ID: 21762
Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape
B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L. Weiss, F.K. Schur, M. Loose, Science 392 (2026).
View | Files available | DOI | PubMed | Europe PMC
 
[38]
2025 | Published | Journal Article | IST-REx-ID: 17884 | OA
Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice
M. Obr, M. Percipalle, D. Chernikova, H. Yang, A. Thader, G. Pinke, D. Porley Esteves, L.M. Mansky, R.A. Dick, F.K. Schur, Nature Structural & Molecular Biology 32 (2025) 268–276.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC | OpenAlexWorkID
 
[37]
2025 | Published | Journal Article | IST-REx-ID: 19795 | OA
Image-based 3D active sample stabilization on the nanometer scale for optical microscopy
J. Vorlaufer, N. Semenov, C. Kreuzinger, M. Javoor, B. Zens, N. Agudelo Duenas, M. Tavakoli, M. Suplata, W. Jahr, J. Lyudchik, A. Wartak, F.K. Schur, J.G. Danzl, Biophysical Reports 5 (2025).
[Published Version] View | Files available | DOI
 
[36]
2025 | Published | Journal Article | IST-REx-ID: 20370 | OA | PlanS
Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
R. Carpentier, J. Kim, M. Capizzi, H. Kim, F. Fäßler, J. Hansen, M.J. Kim, E. Denarier, B. Blot, M. Degennaro, S. Labou, I. Arnal, M.J. Marcaida, M.D. Peraro, D. Kim, F.K. Schur, J.-J. Song, S. Humbert, Science Advances 11 (2025).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[35]
2024 | Published | Journal Article | IST-REx-ID: 14979 | OA
Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores
J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural & Molecular Biology 31 (2024) 1114–1123.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[34]
2024 | Published | Journal Article | IST-REx-ID: 15146 | OA
Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix
B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[33]
2023 | Published | Journal Article | IST-REx-ID: 14255 | OA
The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells
J. Koch, Q. Xin, M. Obr, A. Schäfer, N. Rolfs, H.A. Anagho, A. Kudulyte, L. Woltereck, S. Kummer, J. Campos, Z.M. Uckeley, L. Bell-Sakyi, H.G. Kräusslich, F.K. Schur, C. Acuna, P.Y. Lozach, PLoS Pathogens 19 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[32]
2023 | Research Data | IST-REx-ID: 14562 | OA
Research data of the publication "ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning"
F.K. Schur, (2023).
[Published Version] View | Files available | DOI
 
[31]
2023 | Scientific Software | IST-REx-ID: 14502 | OA
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data
G.A. Dimchev, B. Amiri, F. Fäßler, M. Falcke, F.K. Schur, (2023).
View | Files available | DOI
 
[30]
2023 | Published | Journal Article | IST-REx-ID: 12334 | OA
ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning
F. Fäßler, M. Javoor, J. Datler, H. Döring, F. Hofer, G.A. Dimchev, V.-V. Hodirnau, J. Faix, K. Rottner, F.K. Schur, Science Advances 9 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[29]
2023 | Published | Journal Article | IST-REx-ID: 12421 | OA
Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM
F. Fäßler, M. Javoor, F.K. Schur, Biochemical Society Transactions 51 (2023) 87–99.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[28]
2022 | Published | Journal Article | IST-REx-ID: 11155 | OA
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs
M. Obr, W.J.H. Hagen, R.A. Dick, L. Yu, A. Kotecha, F.K. Schur, Journal of Structural Biology 214 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[27]
2022 | Published | Journal Article | IST-REx-ID: 11351 | OA
Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks
W.J. Nicolas, F. Fäßler, P. Dutka, F.K. Schur, G. Jensen, E. Meyerowitz, Current Biology 32 (2022) P2375-2389.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[26]
2022 | Published | Journal Article | IST-REx-ID: 10639 | OA
The Orthobunyavirus Germiston enters host cells from late endosomes
S. Windhaber, Q. Xin, Z.M. Uckeley, J. Koch, M. Obr, C. Garnier, C. Luengo-Guyonnot, M. Duboeuf, F.K. Schur, P.-Y. Lozach, Journal of Virology 96 (2022).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[25]
2021 | Published | Journal Article | IST-REx-ID: 10103 | OA
A structural perspective of the role of IP6 in immature and mature retroviral assembly
M. Obr, F.K. Schur, R.A. Dick, Viruses 13 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[24]
2021 | Published | Journal Article | IST-REx-ID: 9431 | OA
Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).
[Published Version] View | Files available | DOI | WoS
 
[23]
2021 | Published | Journal Article | IST-REx-ID: 10290 | OA
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data
G.A. Dimchev, B. Amiri, F. Fäßler, M. Falcke, F.K. Schur, Journal of Structural Biology 213 (2021).
[Published Version] View | Files available | DOI | WoS
 
[22]
2021 | Published | Journal Article | IST-REx-ID: 9429 | OA
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
[Published Version] View | Files available | DOI | WoS
 
[21]
2020 | Research Data | IST-REx-ID: 14592 | OA
STL-files for 3D-printed grid holders described in Fäßler F, Zens B, et al.; 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy
F.K. Schur, (2020).
[Published Version] View | Files available | DOI
 
[20]
2020 | Published | Journal Article | IST-REx-ID: 15286
Cryo-electron tomography workflows for quantitative analysis of actin networks involved in cell migration
F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, B. Zens, C. Möhl, F. Bradke, F.K. Schur, Microscopy and Microanalysis 26 (2020) 2518–2519.
View | DOI
 
[19]
2020 | Published | Journal Article | IST-REx-ID: 8971 | OA
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction
F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications 11 (2020).
[Published Version] View | Files available | DOI | WoS
 
[18]
2020 | Published | Journal Article | IST-REx-ID: 7464 | OA
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly
R.A. Dick, C. Xu, D.R. Morado, V. Kravchuk, C.L. Ricana, T.D. Lyddon, A.M. Broad, J.R. Feathers, M.C. Johnson, V.M. Vogt, J.R. Perilla, J.A.G. Briggs, F.K. Schur, PLOS Pathogens 16 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[17]
2020 | Published | Journal Article | IST-REx-ID: 8586 | OA
3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy
F. Fäßler, B. Zens, R. Hauschild, F.K. Schur, Journal of Structural Biology 212 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[16]
2019 | Published | Journal Article | IST-REx-ID: 6343
Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging
F.K. Schur, Current Opinion in Structural Biology 58 (2019) 1–9.
View | DOI | WoS
 
[15]
2019 | Published | Book Chapter | IST-REx-ID: 6890
Structural analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging
M. Obr, F.K. Schur, in:, F.A. Rey (Ed.), Complementary Strategies to Study Virus Structure and Function, Elsevier, 2019, pp. 117–159.
View | DOI | WoS | PubMed | Europe PMC
 
[14]
2018 | Published | Journal Article | IST-REx-ID: 150 | OA
Inositol phosphates are assembly co-factors for HIV-1
R. Dick, K.K. Zadrozny, C. Xu, F.K. Schur, T.D. Lyddon, C.L. Ricana, J.M. Wagner, J.R. Perilla, P.B.K. Ganser, M.C. Johnson, O. Pornillos, V. Vogt, Nature 560 (2018) 509–512.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[13]
2018 | Published | Journal Article | IST-REx-ID: 5770 | OA
Structure and architecture of immature and mature murine leukemia virus capsids
K. Qu, B. Glass, M. Doležal, F.K. Schur, B. Murciano, A. Rein, M. Rumlová, T. Ruml, H.-G. Kräusslich, J.A.G. Briggs, Proceedings of the National Academy of Sciences of the United States of America 115 (2018) E11751–E11760.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[12]
2017 | Published | Journal Article | IST-REx-ID: 817 | OA
Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4Å
B. Turoňová, F.K. Schur, W. Wan, J. Briggs, Journal of Structural Biology 199 (2017) 187–195.
[Published Version] View | Files available | DOI
 
[11]
2016 | Published | Journal Article | IST-REx-ID: 5771 | OA
Retrovirus maturation—an extraordinary structural transformation
S. Mattei, F.K. Schur, J.A. Briggs, Current Opinion in Virology 18 (2016) 27–35.
[Published Version] View | Files available | DOI
 
[10]
2016 | Published | Journal Article | IST-REx-ID: 813 | OA
Nucleic acid binding by Mason-Pfizer monkey virus CA promotes virus assembly and genome packaging
T. Füzik, R. Píchalová, F.K. Schur, K. Strohalmová, I. Křížová, R. Hadravová, M. Rumlová, J. Briggs, P. Ulbrich, T. Ruml, Journal of Virology 90 (2016) 4593–4603.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[9]
2016 | Published | Report | IST-REx-ID: 816
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation
F.K. Schur, M. Obr, W. Hagen, W. Wan, A. Jakobi, J. Kirkpatrick, C. Sachse, H. Kraüsslich, J. Briggs, An Atomic Model of HIV-1 Capsid-SP1 Reveals Structures Regulating Assembly and Maturation, American Association for the Advancement of Science, 2016.
View | DOI | PubMed | Europe PMC
 
[8]
2016 | Published | Journal Article | IST-REx-ID: 1321 | OA
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
[Submitted Version] View | Files available | DOI | WoS
 
[7]
2015 | Published | Journal Article | IST-REx-ID: 814
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution
F.K. Schur, W. Hagen, M. Rumlová, T. Ruml, B. Müller, H. Kraüsslich, J. Briggs, Nature 517 (2015) 505–508.
View | DOI | PubMed | Europe PMC
 
[6]
2015 | Published | Journal Article | IST-REx-ID: 815 | OA
The structure of immature virus like Rous sarcoma virus gag particles reveals a structural role for the p10 domain in assembly
F.K. Schur, R. Dick, W. Hagen, V. Vogt, J. Briggs, Journal of Virology 89 (2015) 10294–10302.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2014 | Published | Journal Article | IST-REx-ID: 809
Cryo electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly
T. Bharata, L. Menendez, W. Hagena, V. Luxd, S. Igonete, M. Schorba, F.K. Schur, H. Kraüsslich, J. Briggsa, PNAS 111 (2014) 8233–8238.
View | DOI | PubMed | Europe PMC
 
[4]
2013 | Published | Journal Article | IST-REx-ID: 810
Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging
F.K. Schur, W. Hagen, A. De Marco, J. Briggs, Journal of Structural Biology 184 (2013) 394–400.
View | DOI
 
[3]
2013 | Published | Journal Article | IST-REx-ID: 811
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
A. Steffen, M. Ladwein, G.A. Dimchev, A. Hein, L. Schwenkmezger, S. Arens, K. Ladwein, J. Holleboom, F.K. Schur, J. Small, J. Schwarz, R. Gerhard, J. Faix, T. Stradal, C. Brakebusch, K. Rottner, Journal of Cell Science 126 (2013) 4572–4588.
View | DOI
 
[2]
2013 | Published | Journal Article | IST-REx-ID: 812
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin
S. Koestler, A. Steffen, M. Nemethova, M. Winterhoff, N. Luo, J. Holleboom, J. Krupp, S. Jacob, M. Vinzenz, F.K. Schur, K. Schlüter, P. Gunning, C. Winkler, C. Schmeiser, J. Faix, T. Stradal, J. Small, K. Rottner, Molecular Biology of the Cell 24 (2013) 2861–2875.
View | DOI
 
[1]
2012 | Published | Journal Article | IST-REx-ID: 808 | OA
Actin branching in the initiation and maintenance of lamellipodia
M. Vinzenz, M. Nemethova, F.K. Schur, J. Mueller, A. Narita, E. Urban, C. Winkler, C. Schmeiser, S. Koestler, K. Rottner, G. Resch, Y. Maéda, J. Small, Journal of Cell Science 125 (2012) 2775–2785.
View | Files available | DOI | WoS
 
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8 Grants


Understanding the mechanism and dynamics of chromatin higher-order structure formation via cross-scale structural analysis

2020-08-01 – 2023-06-30
Österreichische Agentur für Internationale Mobilität und Kooperation in Bildung, Wissenschaft und Forschung

Structural conservation and diversity in retroviral capsid

2018-10-01 – 2021-09-30
Austrian Science Fund

CryoMinflux-guided in-situ molecular census and structure determination (CryoMini)

2021-08-01 – 2025-12-31
Chan Zuckerberg Initiative

Crucial steps in evolution: The rise of genome architecture and function (GenoArch)

2024-09-01 – 2029-08-31
Austrian Science Fund

EMBO Young Investigator Program - Florian Schur

2022-01-01 – 2025-12-31
European Molecular Biology Organization

Structure and isoform diversity of the Arp2/3 complex

2020-07-01 – 2023-06-30
Austrian Science Fund

A molecular atlas of Actin filament IDentities in the cell motility machinery (ActinID)

2023-04-01 – 2028-03-31
European Research Council

Integrated visual proteomics of reciprocal cell-extracellular matrix interactions

2023-03-01 – 2025-02-28
Federation of European Biochemical Societies

41 Publications

Mark all

[41]
2026 | Epub ahead of print | Journal Article | IST-REx-ID: 22372 | OA | PlanS
An intrinsic cytoskeletal oscillator establishes neuronal polarity
T.C. Lin, C.H. Coles, E. Alfadil, F. Fäßler, A. Husch, S. Dupraz, T. Pietralla, A. Narita, M. Schelski, K.C. Flynn, S. Stern, C. Möhl, B.J. Hilton, F. Vauti, H.H. Arnold, F.K. Schur, F. Bradke, Nature (2026).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[40]
2026 | Epub ahead of print | Journal Article | IST-REx-ID: 22403 | OA | PlanS
Gap‐free information transfer in 4D‐STEM via fusion of complementary scattering channels
S. You, G. Varnavides, S. Khavnekar, N. Palatkin, S. Shao, M. Wu, D. Stroppa, D. Chernikova, B. Zhu, R. Egoavil, S. Vespucci, D. Krishnan, X. Ye, F.K. Schur, E. Spiecker, P. Pelz, Advanced Science (2026).
[Published Version] View | DOI | Download Published Version (ext.) | arXiv
 
[39]
2026 | Published | Journal Article | IST-REx-ID: 21762
Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape
B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L. Weiss, F.K. Schur, M. Loose, Science 392 (2026).
View | Files available | DOI | PubMed | Europe PMC
 
[38]
2025 | Published | Journal Article | IST-REx-ID: 17884 | OA
Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice
M. Obr, M. Percipalle, D. Chernikova, H. Yang, A. Thader, G. Pinke, D. Porley Esteves, L.M. Mansky, R.A. Dick, F.K. Schur, Nature Structural & Molecular Biology 32 (2025) 268–276.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC | OpenAlexWorkID
 
[37]
2025 | Published | Journal Article | IST-REx-ID: 19795 | OA
Image-based 3D active sample stabilization on the nanometer scale for optical microscopy
J. Vorlaufer, N. Semenov, C. Kreuzinger, M. Javoor, B. Zens, N. Agudelo Duenas, M. Tavakoli, M. Suplata, W. Jahr, J. Lyudchik, A. Wartak, F.K. Schur, J.G. Danzl, Biophysical Reports 5 (2025).
[Published Version] View | Files available | DOI
 
[36]
2025 | Published | Journal Article | IST-REx-ID: 20370 | OA | PlanS
Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton organization
R. Carpentier, J. Kim, M. Capizzi, H. Kim, F. Fäßler, J. Hansen, M.J. Kim, E. Denarier, B. Blot, M. Degennaro, S. Labou, I. Arnal, M.J. Marcaida, M.D. Peraro, D. Kim, F.K. Schur, J.-J. Song, S. Humbert, Science Advances 11 (2025).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[35]
2024 | Published | Journal Article | IST-REx-ID: 14979 | OA
Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores
J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural & Molecular Biology 31 (2024) 1114–1123.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[34]
2024 | Published | Journal Article | IST-REx-ID: 15146 | OA
Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix
B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[33]
2023 | Published | Journal Article | IST-REx-ID: 14255 | OA
The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells
J. Koch, Q. Xin, M. Obr, A. Schäfer, N. Rolfs, H.A. Anagho, A. Kudulyte, L. Woltereck, S. Kummer, J. Campos, Z.M. Uckeley, L. Bell-Sakyi, H.G. Kräusslich, F.K. Schur, C. Acuna, P.Y. Lozach, PLoS Pathogens 19 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[32]
2023 | Research Data | IST-REx-ID: 14562 | OA
Research data of the publication "ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning"
F.K. Schur, (2023).
[Published Version] View | Files available | DOI
 
[31]
2023 | Scientific Software | IST-REx-ID: 14502 | OA
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data
G.A. Dimchev, B. Amiri, F. Fäßler, M. Falcke, F.K. Schur, (2023).
View | Files available | DOI
 
[30]
2023 | Published | Journal Article | IST-REx-ID: 12334 | OA
ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning
F. Fäßler, M. Javoor, J. Datler, H. Döring, F. Hofer, G.A. Dimchev, V.-V. Hodirnau, J. Faix, K. Rottner, F.K. Schur, Science Advances 9 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[29]
2023 | Published | Journal Article | IST-REx-ID: 12421 | OA
Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM
F. Fäßler, M. Javoor, F.K. Schur, Biochemical Society Transactions 51 (2023) 87–99.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[28]
2022 | Published | Journal Article | IST-REx-ID: 11155 | OA
Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs
M. Obr, W.J.H. Hagen, R.A. Dick, L. Yu, A. Kotecha, F.K. Schur, Journal of Structural Biology 214 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[27]
2022 | Published | Journal Article | IST-REx-ID: 11351 | OA
Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks
W.J. Nicolas, F. Fäßler, P. Dutka, F.K. Schur, G. Jensen, E. Meyerowitz, Current Biology 32 (2022) P2375-2389.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[26]
2022 | Published | Journal Article | IST-REx-ID: 10639 | OA
The Orthobunyavirus Germiston enters host cells from late endosomes
S. Windhaber, Q. Xin, Z.M. Uckeley, J. Koch, M. Obr, C. Garnier, C. Luengo-Guyonnot, M. Duboeuf, F.K. Schur, P.-Y. Lozach, Journal of Virology 96 (2022).
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[25]
2021 | Published | Journal Article | IST-REx-ID: 10103 | OA
A structural perspective of the role of IP6 in immature and mature retroviral assembly
M. Obr, F.K. Schur, R.A. Dick, Viruses 13 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[24]
2021 | Published | Journal Article | IST-REx-ID: 9431 | OA
Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).
[Published Version] View | Files available | DOI | WoS
 
[23]
2021 | Published | Journal Article | IST-REx-ID: 10290 | OA
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data
G.A. Dimchev, B. Amiri, F. Fäßler, M. Falcke, F.K. Schur, Journal of Structural Biology 213 (2021).
[Published Version] View | Files available | DOI | WoS
 
[22]
2021 | Published | Journal Article | IST-REx-ID: 9429 | OA
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
[Published Version] View | Files available | DOI | WoS
 
[21]
2020 | Research Data | IST-REx-ID: 14592 | OA
STL-files for 3D-printed grid holders described in Fäßler F, Zens B, et al.; 3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy
F.K. Schur, (2020).
[Published Version] View | Files available | DOI
 
[20]
2020 | Published | Journal Article | IST-REx-ID: 15286
Cryo-electron tomography workflows for quantitative analysis of actin networks involved in cell migration
F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, B. Zens, C. Möhl, F. Bradke, F.K. Schur, Microscopy and Microanalysis 26 (2020) 2518–2519.
View | DOI
 
[19]
2020 | Published | Journal Article | IST-REx-ID: 8971 | OA
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction
F. Fäßler, G.A. Dimchev, V.-V. Hodirnau, W. Wan, F.K. Schur, Nature Communications 11 (2020).
[Published Version] View | Files available | DOI | WoS
 
[18]
2020 | Published | Journal Article | IST-REx-ID: 7464 | OA
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly
R.A. Dick, C. Xu, D.R. Morado, V. Kravchuk, C.L. Ricana, T.D. Lyddon, A.M. Broad, J.R. Feathers, M.C. Johnson, V.M. Vogt, J.R. Perilla, J.A.G. Briggs, F.K. Schur, PLOS Pathogens 16 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[17]
2020 | Published | Journal Article | IST-REx-ID: 8586 | OA
3D printed cell culture grid holders for improved cellular specimen preparation in cryo-electron microscopy
F. Fäßler, B. Zens, R. Hauschild, F.K. Schur, Journal of Structural Biology 212 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[16]
2019 | Published | Journal Article | IST-REx-ID: 6343
Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging
F.K. Schur, Current Opinion in Structural Biology 58 (2019) 1–9.
View | DOI | WoS
 
[15]
2019 | Published | Book Chapter | IST-REx-ID: 6890
Structural analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging
M. Obr, F.K. Schur, in:, F.A. Rey (Ed.), Complementary Strategies to Study Virus Structure and Function, Elsevier, 2019, pp. 117–159.
View | DOI | WoS | PubMed | Europe PMC
 
[14]
2018 | Published | Journal Article | IST-REx-ID: 150 | OA
Inositol phosphates are assembly co-factors for HIV-1
R. Dick, K.K. Zadrozny, C. Xu, F.K. Schur, T.D. Lyddon, C.L. Ricana, J.M. Wagner, J.R. Perilla, P.B.K. Ganser, M.C. Johnson, O. Pornillos, V. Vogt, Nature 560 (2018) 509–512.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[13]
2018 | Published | Journal Article | IST-REx-ID: 5770 | OA
Structure and architecture of immature and mature murine leukemia virus capsids
K. Qu, B. Glass, M. Doležal, F.K. Schur, B. Murciano, A. Rein, M. Rumlová, T. Ruml, H.-G. Kräusslich, J.A.G. Briggs, Proceedings of the National Academy of Sciences of the United States of America 115 (2018) E11751–E11760.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[12]
2017 | Published | Journal Article | IST-REx-ID: 817 | OA
Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4Å
B. Turoňová, F.K. Schur, W. Wan, J. Briggs, Journal of Structural Biology 199 (2017) 187–195.
[Published Version] View | Files available | DOI
 
[11]
2016 | Published | Journal Article | IST-REx-ID: 5771 | OA
Retrovirus maturation—an extraordinary structural transformation
S. Mattei, F.K. Schur, J.A. Briggs, Current Opinion in Virology 18 (2016) 27–35.
[Published Version] View | Files available | DOI
 
[10]
2016 | Published | Journal Article | IST-REx-ID: 813 | OA
Nucleic acid binding by Mason-Pfizer monkey virus CA promotes virus assembly and genome packaging
T. Füzik, R. Píchalová, F.K. Schur, K. Strohalmová, I. Křížová, R. Hadravová, M. Rumlová, J. Briggs, P. Ulbrich, T. Ruml, Journal of Virology 90 (2016) 4593–4603.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[9]
2016 | Published | Report | IST-REx-ID: 816
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation
F.K. Schur, M. Obr, W. Hagen, W. Wan, A. Jakobi, J. Kirkpatrick, C. Sachse, H. Kraüsslich, J. Briggs, An Atomic Model of HIV-1 Capsid-SP1 Reveals Structures Regulating Assembly and Maturation, American Association for the Advancement of Science, 2016.
View | DOI | PubMed | Europe PMC
 
[8]
2016 | Published | Journal Article | IST-REx-ID: 1321 | OA
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
[Submitted Version] View | Files available | DOI | WoS
 
[7]
2015 | Published | Journal Article | IST-REx-ID: 814
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution
F.K. Schur, W. Hagen, M. Rumlová, T. Ruml, B. Müller, H. Kraüsslich, J. Briggs, Nature 517 (2015) 505–508.
View | DOI | PubMed | Europe PMC
 
[6]
2015 | Published | Journal Article | IST-REx-ID: 815 | OA
The structure of immature virus like Rous sarcoma virus gag particles reveals a structural role for the p10 domain in assembly
F.K. Schur, R. Dick, W. Hagen, V. Vogt, J. Briggs, Journal of Virology 89 (2015) 10294–10302.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[5]
2014 | Published | Journal Article | IST-REx-ID: 809
Cryo electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly
T. Bharata, L. Menendez, W. Hagena, V. Luxd, S. Igonete, M. Schorba, F.K. Schur, H. Kraüsslich, J. Briggsa, PNAS 111 (2014) 8233–8238.
View | DOI | PubMed | Europe PMC
 
[4]
2013 | Published | Journal Article | IST-REx-ID: 810
Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging
F.K. Schur, W. Hagen, A. De Marco, J. Briggs, Journal of Structural Biology 184 (2013) 394–400.
View | DOI
 
[3]
2013 | Published | Journal Article | IST-REx-ID: 811
Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
A. Steffen, M. Ladwein, G.A. Dimchev, A. Hein, L. Schwenkmezger, S. Arens, K. Ladwein, J. Holleboom, F.K. Schur, J. Small, J. Schwarz, R. Gerhard, J. Faix, T. Stradal, C. Brakebusch, K. Rottner, Journal of Cell Science 126 (2013) 4572–4588.
View | DOI
 
[2]
2013 | Published | Journal Article | IST-REx-ID: 812
Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin
S. Koestler, A. Steffen, M. Nemethova, M. Winterhoff, N. Luo, J. Holleboom, J. Krupp, S. Jacob, M. Vinzenz, F.K. Schur, K. Schlüter, P. Gunning, C. Winkler, C. Schmeiser, J. Faix, T. Stradal, J. Small, K. Rottner, Molecular Biology of the Cell 24 (2013) 2861–2875.
View | DOI
 
[1]
2012 | Published | Journal Article | IST-REx-ID: 808 | OA
Actin branching in the initiation and maintenance of lamellipodia
M. Vinzenz, M. Nemethova, F.K. Schur, J. Mueller, A. Narita, E. Urban, C. Winkler, C. Schmeiser, S. Koestler, K. Rottner, G. Resch, Y. Maéda, J. Small, Journal of Cell Science 125 (2012) 2775–2785.
View | Files available | DOI | WoS
 
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