Florian M Praetorius

Praetorius Group

18 Publications

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[18]
2024 | Published | Journal Article | IST-REx-ID: 17463 | OA
De novo design of allosterically switchable protein assemblies
A. Pillai, A. Idris, A. Philomin, C. Weidle, R. Skotheim, P.J.Y. Leung, A. Broerman, C. Demakis, A.J. Borst, F.M. Praetorius, D. Baker, Nature 632 (2024) 911–920.
[Published Version] View | Files available | DOI
 
[17]
2023 | Published | Journal Article | IST-REx-ID: 14281
Design of stimulus-responsive two-state hinge proteins
Praetorius FM, Leung PJY, Tessmer MH, Broerman A, Demakis C, Dishman AF, Pillai A, Idris A, Juergens D, Dauparas J, Li X, Levine PM, Lamb M, Ballard RK, Gerben SR, Nguyen H, Kang A, Sankaran B, Bera AK, Volkman BF, Nivala J, Stoll S, Baker D. 2023. Design of stimulus-responsive two-state hinge proteins. Science. 381(6659), 754–760.
View | DOI | PubMed | Europe PMC
 
[16]
2023 | Submitted | Preprint | IST-REx-ID: 14294 | OA
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An S, Favor A, Ehnes D, Li Z, Praetorius FM, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray AN, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. bioRxiv, 10.1101/2023.03.14.532666.
[Preprint] View | DOI | Download Preprint (ext.)
 
[15]
2022 | Published | Journal Article | IST-REx-ID: 14282
Reconfigurable asymmetric protein assemblies through implicit negative design
D.D. Sahtoe, F.M. Praetorius, A. Courbet, Y. Hsia, B.I.M. Wicky, N.I. Edman, L.M. Miller, B.J.R. Timmermans, J. Decarreau, H.M. Morris, A. Kang, A.K. Bera, D. Baker, Science 375 (2022).
View | DOI | PubMed | Europe PMC
 
[14]
2019 | Published | Journal Article | IST-REx-ID: 14299 | OA
Custom-size, functional, and durable DNA origami with design-specific scaffolds
E. FAS, F.M. Praetorius, C. Wachauf, G. Brüggenthies, F. Kohler, B. Kick, K. Kadletz, P. Pham, K. Behler, T. Gerling, H. Dietz, ACS Nano 13 (2019) 5015–5027.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[13]
2018 | Published | Journal Article | IST-REx-ID: 14284 | OA
Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB
B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[12]
2018 | Published | Thesis | IST-REx-ID: 14306 | OA
Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures
F.M. Praetorius, Genetically Encoding the Spatial Arrangement of DNA and Proteins in Self-Assembling Nanostructures, Technische Universität München, 2018.
[Published Version] View | Download Published Version (ext.)
 
[11]
2017 | Published | Journal Article | IST-REx-ID: 14286
Specific growth rate and multiplicity of infection affect high-cell-density fermentation with bacteriophage M13 for ssDNA production
B. Kick, S. Hensler, F.M. Praetorius, H. Dietz, D. Weuster-Botz, Biotechnology and Bioengineering 114 (2017) 777–784.
View | DOI | PubMed | Europe PMC
 
[10]
2017 | Published | Journal Article | IST-REx-ID: 14287
Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes
F.M. Praetorius, H. Dietz, Science 355 (2017).
View | DOI | PubMed | Europe PMC
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 14290
Biotechnological mass production of DNA origami
F.M. Praetorius, B. Kick, K.L. Behler, M.N. Honemann, D. Weuster-Botz, H. Dietz, Nature 552 (2017) 84–87.
View | DOI | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 14308
Genetically encoded DNA-protein hybrid origami
F.M. Praetorius, H. Dietz, Biophysical Journal 112 (2017).
View | DOI
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 14309 | OA
Molecular engineering of chiral colloidal liquid crystals using DNA origami
M. Siavashpouri, C. Wachauf, M. Zakhary, F.M. Praetorius, H. Dietz, Z. Dogic, Nature Materials 16 (2017) 849–856.
[Preprint] View | DOI | Download Preprint (ext.) | PubMed | Europe PMC | arXiv
 
[6]
2017 | Published | Conference Abstract | IST-REx-ID: 14310
Molecular engineering of colloidal liquid crystals using DNA origami
M. Siavashpouri, C. Wachauf, M. Zakhary, F.M. Praetorius, H. Dietz, Z. Dogic, in:, APS March Meeting 2017, APS, 2017.
View
 
[5]
2016 | Published | Journal Article | IST-REx-ID: 14302
Impact of heterogeneity and lattice bond strength on DNA triangle crystal growth
E. Stahl, F.M. Praetorius, C.C. de Oliveira Mann, K.-P. Hopfner, H. Dietz, ACS Nano 10 (2016) 9156–9164.
View | DOI | PubMed | Europe PMC
 
[4]
2016 | Published | Journal Article | IST-REx-ID: 14304
Design of a molecular support for cryo-EM structure determination
T.G. Martin, T.A.M. Bharat, A.C. Joerger, X. Bai, F.M. Praetorius, A.R. Fersht, H. Dietz, S.H.W. Scheres, PNAS 113 (2016) E7456–E7463.
[Published Version] View | DOI | PubMed | Europe PMC
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 14303 | OA
Efficient production of single-stranded phage DNA as scaffolds for DNA origami
B. Kick, F.M. Praetorius, H. Dietz, D. Weuster-Botz, Nano Letters 15 (2015) 4672–4676.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 14301 | OA
Facile and scalable preparation of pure and dense DNA origami solutions
E. Stahl, T. Martin, F.M. Praetorius, H. Dietz, Angewandte Chemie International Edition 126 (2014) 12949–12954.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[1]
2011 | Published | Journal Article | IST-REx-ID: 14305 | OA
Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
A. Bachmann, D. Wildemann, F.M. Praetorius, G. Fischer, T. Kiefhaber, PNAS 108 (2011) 3952–3957.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
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18 Publications

Mark all

[18]
2024 | Published | Journal Article | IST-REx-ID: 17463 | OA
De novo design of allosterically switchable protein assemblies
A. Pillai, A. Idris, A. Philomin, C. Weidle, R. Skotheim, P.J.Y. Leung, A. Broerman, C. Demakis, A.J. Borst, F.M. Praetorius, D. Baker, Nature 632 (2024) 911–920.
[Published Version] View | Files available | DOI
 
[17]
2023 | Published | Journal Article | IST-REx-ID: 14281
Design of stimulus-responsive two-state hinge proteins
Praetorius FM, Leung PJY, Tessmer MH, Broerman A, Demakis C, Dishman AF, Pillai A, Idris A, Juergens D, Dauparas J, Li X, Levine PM, Lamb M, Ballard RK, Gerben SR, Nguyen H, Kang A, Sankaran B, Bera AK, Volkman BF, Nivala J, Stoll S, Baker D. 2023. Design of stimulus-responsive two-state hinge proteins. Science. 381(6659), 754–760.
View | DOI | PubMed | Europe PMC
 
[16]
2023 | Submitted | Preprint | IST-REx-ID: 14294 | OA
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Edman NI, Redler RL, Phal A, Schlichthaerle T, Srivatsan SR, Etemadi A, An S, Favor A, Ehnes D, Li Z, Praetorius FM, Gordon M, Yang W, Coventry B, Hicks DR, Cao L, Bethel N, Heine P, Murray AN, Gerben S, Carter L, Miranda M, Negahdari B, Lee S, Trapnell C, Stewart L, Ekiert DC, Schlessinger J, Shendure J, Bhabha G, Ruohola-Baker H, Baker D. Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. bioRxiv, 10.1101/2023.03.14.532666.
[Preprint] View | DOI | Download Preprint (ext.)
 
[15]
2022 | Published | Journal Article | IST-REx-ID: 14282
Reconfigurable asymmetric protein assemblies through implicit negative design
D.D. Sahtoe, F.M. Praetorius, A. Courbet, Y. Hsia, B.I.M. Wicky, N.I. Edman, L.M. Miller, B.J.R. Timmermans, J. Decarreau, H.M. Morris, A. Kang, A.K. Bera, D. Baker, Science 375 (2022).
View | DOI | PubMed | Europe PMC
 
[14]
2019 | Published | Journal Article | IST-REx-ID: 14299 | OA
Custom-size, functional, and durable DNA origami with design-specific scaffolds
E. FAS, F.M. Praetorius, C. Wachauf, G. Brüggenthies, F. Kohler, B. Kick, K. Kadletz, P. Pham, K. Behler, T. Gerling, H. Dietz, ACS Nano 13 (2019) 5015–5027.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[13]
2018 | Published | Journal Article | IST-REx-ID: 14284 | OA
Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB
B. Bräuning, E. Bertosin, F.M. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, M. Groll, Nature Communications 9 (2018).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[12]
2018 | Published | Thesis | IST-REx-ID: 14306 | OA
Genetically encoding the spatial arrangement of DNA and proteins in self-assembling nanostructures
F.M. Praetorius, Genetically Encoding the Spatial Arrangement of DNA and Proteins in Self-Assembling Nanostructures, Technische Universität München, 2018.
[Published Version] View | Download Published Version (ext.)
 
[11]
2017 | Published | Journal Article | IST-REx-ID: 14286
Specific growth rate and multiplicity of infection affect high-cell-density fermentation with bacteriophage M13 for ssDNA production
B. Kick, S. Hensler, F.M. Praetorius, H. Dietz, D. Weuster-Botz, Biotechnology and Bioengineering 114 (2017) 777–784.
View | DOI | PubMed | Europe PMC
 
[10]
2017 | Published | Journal Article | IST-REx-ID: 14287
Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes
F.M. Praetorius, H. Dietz, Science 355 (2017).
View | DOI | PubMed | Europe PMC
 
[9]
2017 | Published | Journal Article | IST-REx-ID: 14290
Biotechnological mass production of DNA origami
F.M. Praetorius, B. Kick, K.L. Behler, M.N. Honemann, D. Weuster-Botz, H. Dietz, Nature 552 (2017) 84–87.
View | DOI | PubMed | Europe PMC
 
[8]
2017 | Published | Journal Article | IST-REx-ID: 14308
Genetically encoded DNA-protein hybrid origami
F.M. Praetorius, H. Dietz, Biophysical Journal 112 (2017).
View | DOI
 
[7]
2017 | Published | Journal Article | IST-REx-ID: 14309 | OA
Molecular engineering of chiral colloidal liquid crystals using DNA origami
M. Siavashpouri, C. Wachauf, M. Zakhary, F.M. Praetorius, H. Dietz, Z. Dogic, Nature Materials 16 (2017) 849–856.
[Preprint] View | DOI | Download Preprint (ext.) | PubMed | Europe PMC | arXiv
 
[6]
2017 | Published | Conference Abstract | IST-REx-ID: 14310
Molecular engineering of colloidal liquid crystals using DNA origami
M. Siavashpouri, C. Wachauf, M. Zakhary, F.M. Praetorius, H. Dietz, Z. Dogic, in:, APS March Meeting 2017, APS, 2017.
View
 
[5]
2016 | Published | Journal Article | IST-REx-ID: 14302
Impact of heterogeneity and lattice bond strength on DNA triangle crystal growth
E. Stahl, F.M. Praetorius, C.C. de Oliveira Mann, K.-P. Hopfner, H. Dietz, ACS Nano 10 (2016) 9156–9164.
View | DOI | PubMed | Europe PMC
 
[4]
2016 | Published | Journal Article | IST-REx-ID: 14304
Design of a molecular support for cryo-EM structure determination
T.G. Martin, T.A.M. Bharat, A.C. Joerger, X. Bai, F.M. Praetorius, A.R. Fersht, H. Dietz, S.H.W. Scheres, PNAS 113 (2016) E7456–E7463.
[Published Version] View | DOI | PubMed | Europe PMC
 
[3]
2015 | Published | Journal Article | IST-REx-ID: 14303 | OA
Efficient production of single-stranded phage DNA as scaffolds for DNA origami
B. Kick, F.M. Praetorius, H. Dietz, D. Weuster-Botz, Nano Letters 15 (2015) 4672–4676.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[2]
2014 | Published | Journal Article | IST-REx-ID: 14301 | OA
Facile and scalable preparation of pure and dense DNA origami solutions
E. Stahl, T. Martin, F.M. Praetorius, H. Dietz, Angewandte Chemie International Edition 126 (2014) 12949–12954.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[1]
2011 | Published | Journal Article | IST-REx-ID: 14305 | OA
Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
A. Bachmann, D. Wildemann, F.M. Praetorius, G. Fischer, T. Kiefhaber, PNAS 108 (2011) 3952–3957.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
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