Leonid A Sazanov

Sazanov Group

73 Publications

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[73]
2024 | Journal Article | IST-REx-ID: 15323
Vercellino, Irene, and Leonid A Sazanov. “SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes.” Nature Structural and Molecular Biology. Springer Nature, 2024. https://doi.org/10.1038/s41594-024-01255-0.
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[72]
2023 | Journal Article | IST-REx-ID: 12757 | OA
Sazanov, Leonid A. “From the ‘black Box’ to ‘Domino Effect’ Mechanism: What Have We Learned from the Structures of Respiratory Complex I.” The Biochemical Journal. Portland Press, 2023. https://doi.org/10.1042/BCJ20210285.
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[71]
2023 | Journal Article | IST-REx-ID: 14040 | OA
Zhao, Ziyu, Irene Vercellino, Jana Knoppová, Roman Sobotka, James W. Murray, Peter J. Nixon, Leonid A Sazanov, and Josef Komenda. “The Ycf48 Accessory Factor Occupies the Site of the Oxygen-Evolving Manganese Cluster during Photosystem II Biogenesis.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-40388-6.
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[70]
2022 | Journal Article | IST-REx-ID: 10182
Vercellino, Irene, and Leonid A Sazanov. “The Assembly, Regulation and Function of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular Cell Biology. Springer Nature, 2022. https://doi.org/10.1038/s41580-021-00415-0.
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[69]
2022 | Journal Article | IST-REx-ID: 11167 | OA
Kampjut, Domen, and Leonid A Sazanov. “Structure of Respiratory Complex I – An Emerging Blueprint for the Mechanism.” Current Opinion in Structural Biology. Elsevier, 2022. https://doi.org/10.1016/j.sbi.2022.102350.
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[68]
2022 | Journal Article | IST-REx-ID: 11551 | OA
Molina-Granada, David, Emiliano González-Vioque, Marris G. Dibley, Raquel Cabrera-Pérez, Antoni Vallbona-Garcia, Javier Torres-Torronteras, Leonid A Sazanov, Michael T. Ryan, Yolanda Cámara, and Ramon Martí. “Most Mitochondrial DGTP Is Tightly Bound to Respiratory Complex I through the NDUFA10 Subunit.” Communications Biology. Springer Nature, 2022. https://doi.org/10.1038/s42003-022-03568-6.
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[67]
2022 | Journal Article | IST-REx-ID: 12138 | OA
Kravchuk, Vladyslav, Olga Petrova, Domen Kampjut, Anna Wojciechowska-Bason, Zara Breese, and Leonid A Sazanov. “A Universal Coupling Mechanism of Respiratory Complex I.” Nature. Springer Nature, 2022. https://doi.org/10.1038/s41586-022-05199-7.
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[66]
2021 | Journal Article | IST-REx-ID: 8993 | OA
Abas, Lindy, Martina Kolb, Johannes Stadlmann, Dorina P. Janacek, Kristina Lukic, Claus Schwechheimer, Leonid A Sazanov, Lukas Mach, Jiří Friml, and Ulrich Z. Hammes. “Naphthylphthalamic Acid Associates with and Inhibits PIN Auxin Transporters.” PNAS. National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.2020857118.
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[65]
2021 | Journal Article | IST-REx-ID: 9205 | OA
Kampjut, Domen, Julia Steiner, and Leonid A Sazanov. “Cryo-EM Grid Optimization for Membrane Proteins.” IScience. Elsevier, 2021. https://doi.org/10.1016/j.isci.2021.102139.
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[64]
2021 | Journal Article | IST-REx-ID: 10146
Vercellino, Irene, and Leonid A Sazanov. “Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV.” Nature. Springer Nature, 2021. https://doi.org/10.1038/s41586-021-03927-z.
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[63]
2020 | Journal Article | IST-REx-ID: 7788 | OA
Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand, et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2020. https://doi.org/10.1016/j.bbabio.2020.148213.
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[62]
2020 | Journal Article | IST-REx-ID: 8040
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M. R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I.” Journal of the American Chemical Society. American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.
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[61]
2020 | Research Data Reference | IST-REx-ID: 9326 | OA
Gupta, Chitrak, Umesh Khaniya, Chun Chan, Francois Dehez, Mrinal Shekhar, M. R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I.” American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.s002.
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[60]
2020 | Research Data Reference | IST-REx-ID: 9713
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Supporting Information.” American Chemical Society , 2020. https://doi.org/10.1021/jacs.9b13450.s001.
[Published Version] View | Files available | DOI
 
[59]
2020 | Research Data Reference | IST-REx-ID: 9878
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Movies.” American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[58]
2020 | Journal Article | IST-REx-ID: 8318 | OA
Gutierrez-Fernandez, Javier, Karol Kaszuba, Gurdeep S. Minhas, Rozbeh Baradaran, Margherita Tambalo, David T. Gallagher, and Leonid A Sazanov. “Key Role of Quinone in the Mechanism of Respiratory Complex I.” Nature Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-020-17957-0.
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[57]
2020 | Journal Article | IST-REx-ID: 8581
Pinke, Gergely, Long Zhou, and Leonid A Sazanov. “Cryo-EM Structure of the Entire Mammalian F-Type ATP Synthase.” Nature Structural and Molecular Biology. Springer Nature, 2020. https://doi.org/10.1038/s41594-020-0503-8.
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[56]
2020 | Journal Article | IST-REx-ID: 8737 | OA
Kampjut, Domen, and Leonid A Sazanov. “The Coupling Mechanism of Mammalian Respiratory Complex I.” Science. American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.abc4209.
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[55]
2020 | Journal Article | IST-REx-ID: 8284 | OA
Steiner, Julia, and Leonid A Sazanov. “Structure and Mechanism of the Mrp Complex, an Ancient Cation/Proton Antiporter.” ELife. eLife Sciences Publications, 2020. https://doi.org/10.7554/eLife.59407.
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[54]
2019 | Journal Article | IST-REx-ID: 6859
Zhou, Long, and Leonid A Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science. AAAS, 2019. https://doi.org/10.1126/science.aaw9144.
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[53]
2019 | Journal Article | IST-REx-ID: 7395 | OA
Letts, James A, Karol Fiedorczuk, Gianluca Degliesposti, Mark Skehel, and Leonid A Sazanov. “Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk.” Molecular Cell. Cell Press, 2019. https://doi.org/10.1016/j.molcel.2019.07.022.
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[52]
2019 | Journal Article | IST-REx-ID: 6848 | OA
Kampjut, Domen, and Leonid A Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” Nature. Springer Nature, 2019. https://doi.org/10.1038/s41586-019-1519-2.
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[51]
2018 | Journal Article | IST-REx-ID: 152 | OA
Fiedorczuk, Karol, and Leonid A Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” Trends in Cell Biology. Elsevier, 2018. https://doi.org/10.1016/j.tcb.2018.06.006.
[Submitted Version] View | Files available | DOI | WoS
 
[50]
2017 | Journal Article | IST-REx-ID: 443 | OA
Hardie, Rae, Ellen Van Dam, Mark Cowley, Ting Han, Seher Balaban, Marina Pajic, Mark Pinese, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism. BioMed Central, 2017. https://doi.org/10.1186/s40170-017-0164-1.
[Published Version] View | Files available | DOI
 
[49]
2017 | Book Chapter | IST-REx-ID: 444
Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” In Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, 25–59. Mechanisms of Primary Energy Transduction in Biology . Royal Society of Chemistry, 2017. https://doi.org/10.1039/9781788010405-00025.
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[48]
2017 | Journal Article | IST-REx-ID: 515 | OA
Letts, James A, and Leonid A Sazanov. “Clarifying the Supercomplex: The Higher-Order Organization of the Mitochondrial Electron Transport Chain.” Nature Structural and Molecular Biology. Nature Publishing Group, 2017. https://doi.org/10.1038/nsmb.3460.
[Submitted Version] View | Files available | DOI
 
[47]
2016 | Journal Article | IST-REx-ID: 1209 | OA
Letts, James A, Gianluca Degliesposti, Karol Fiedorczuk, Mark Skehel, and Leonid A Sazanov. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2016. https://doi.org/10.1074/jbc.M116.735142.
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[46]
2016 | Journal Article | IST-REx-ID: 1226 | OA
Fiedorczuk, Karol, James A Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel, and Leonid A Sazanov. “Atomic Structure of the Entire Mammalian Mitochondrial Complex I.” Nature. Nature Publishing Group, 2016. https://doi.org/10.1038/nature19794.
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[45]
2016 | Journal Article | IST-REx-ID: 1232
Letts, James A, Karol Fiedorczuk, and Leonid A Sazanov. “The Architecture of Respiratory Supercomplexes.” Nature. Nature Publishing Group, 2016. https://doi.org/10.1038/nature19774.
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[44]
2016 | Journal Article | IST-REx-ID: 1288
Holt, Peter, Rouslan Efremov, Eiko Nakamaru Ogiso, and Leonid A Sazanov. “Reversible FMN Dissociation from Escherichia Coli Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2016. https://doi.org/10.1016/j.bbabio.2016.08.008.
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[43]
2016 | Journal Article | IST-REx-ID: 1521
Berrisford, John, Rozbeh Baradaran, and Leonid A Sazanov. “Structure of Bacterial Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2016. https://doi.org/10.1016/j.bbabio.2016.01.012.
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[42]
2015 | Journal Article | IST-REx-ID: 1638
Sazanov, Leonid A. “A Giant Molecular Proton Pump: Structure and Mechanism of Respiratory Complex I.” Nature Reviews Molecular Cell Biology. Nature Publishing Group, 2015. https://doi.org/10.1038/nrm3997.
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[41]
2015 | Journal Article | IST-REx-ID: 1683
Letts, James A, and Leonid A Sazanov. “Gaining Mass: The Structure of Respiratory Complex I-from Bacterial towards Mitochondrial Versions.” Current Opinion in Structural Biology. Elsevier, 2015. https://doi.org/10.1016/j.sbi.2015.08.008.
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[40]
2014 | Book Review | IST-REx-ID: 1981
Garvin, Michael, Joseph Bielawski, Leonid A Sazanov, and Anthony Gharrett. “Review and Meta-Analysis of Natural Selection in Mitochondrial Complex I in Metazoans.” Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell, 2014. https://doi.org/10.1111/jzs.12079.
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[39]
2014 | Journal Article | IST-REx-ID: 1980
Heikal, Adam, Yoshio Nakatani, Elyse Dunn, Marion Weimar, Catherine Day, Edward Baker, Shaun Lott, Leonid A Sazanov, and Gregory Cook. “Structure of the Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular Microbiology. Wiley-Blackwell, 2014. https://doi.org/10.1111/mmi.12507.
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[38]
2014 | Journal Article | IST-REx-ID: 1979
Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer and Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics and Biomembranes. Springer, 2014. https://doi.org/10.1007/s10863-014-9554-z.
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[37]
2013 | Journal Article | IST-REx-ID: 1977
Sazanov, Leonid A, Rozbeh Baradaran, Rouslan Efremov, John Berrisford, and Gurdeep Minhas. “A Long Road towards the Structure of Respiratory Complex I, a Giant Molecular Proton Pump.” Biochemical Society Transactions. Portland Press, 2013. https://doi.org/10.1042/BST20130193.
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[36]
2013 | Journal Article | IST-REx-ID: 1978
Baradaran, Rozbeh, John Berrisford, Gurdeep Minhas, and Leonid A Sazanov. “Crystal Structure of the Entire Respiratory Complex I.” Nature. Nature Publishing Group, 2013. https://doi.org/10.1038/nature11871.
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[35]
2012 | Book Review | IST-REx-ID: 1976
Efremov, Rouslan, and Leonid A Sazanov. “The Coupling Mechanism of Respiratory Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2012. https://doi.org/10.1016/j.bbabio.2012.02.015.
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[34]
2012 | Journal Article | IST-REx-ID: 1972
Efremov, Rouslan, and Leonid A Sazanov. “Structure of Escherichia Coli OmpF Porin from Lipidic Mesophase.” Journal of Structural Biology. Academic Press, 2012. https://doi.org/10.1016/j.jsb.2012.03.005.
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[33]
2011 | Journal Article | IST-REx-ID: 1975
Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and Leonid A Sazanov. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2011. https://doi.org/10.1074/jbc.M110.194993.
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[32]
2011 | Journal Article | IST-REx-ID: 1973
Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature. Nature Publishing Group, 2011. https://doi.org/10.1038/nature10330.
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[31]
2011 | Journal Article | IST-REx-ID: 1974
Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology. Elsevier, 2011. https://doi.org/10.1016/j.sbi.2011.07.002.
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[30]
2010 | Journal Article | IST-REx-ID: 1970
Efremov, Rouslan, Rozbeh Baradaran, and Leonid A Sazanov. “The Architecture of Respiratory Complex I.” Nature. Nature Publishing Group, 2010. https://doi.org/10.1038/nature09066.
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[29]
2009 | Journal Article | IST-REx-ID: 1971
Berrisford, John, and Leonid A Sazanov. “Structural Basis for the Mechanism of Respiratory Complex I.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2009. https://doi.org/10.1074/jbc.M109.032144.
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[28]
2008 | Journal Article | IST-REx-ID: 1967
Berrisford, John, Christopher Thompson, and Leonid A Sazanov. “Chemical and NADH-Induced, ROS-Dependent, Cross-Linking between Sublimits of Complex I from Escherichia Coli and Thermus Thermophilus.” Biochemistry. ACS, 2008. https://doi.org/10.1021/bi801160u.
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[27]
2008 | Journal Article | IST-REx-ID: 1968
Morgan, David, and Leonid A Sazanov. “Three-Dimensional Structure of Respiratory Complex I from Escherichia Coli in Ice in the Presence of Nucleotides.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2008. https://doi.org/10.1016/j.bbabio.2008.03.023.
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[26]
2007 | Journal Article | IST-REx-ID: 1965
Baranova, Ekaterina, Peter Holt, and Leonid A Sazanov. “Projection Structure of the Membrane Domain of Escherichia Coli Respiratory Complex I at 8 Å Resolution.” Journal of Molecular Biology. Elsevier, 2007. https://doi.org/10.1016/j.jmb.2006.11.026.
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[25]
2007 | Journal Article | IST-REx-ID: 1969
Baranova, Ekaterina, David Morgan, and Leonid A Sazanov. “Single Particle Analysis Confirms Distal Location of Subunits NuoL and NuoM in Escherichia Coli Complex I.” Journal of Structural Biology. Academic Press, 2007. https://doi.org/10.1016/j.jsb.2007.01.009.
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[24]
2007 | Journal Article | IST-REx-ID: 1964
Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural Insights Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry. ACS, 2007. https://doi.org/10.1021/bi602508x.
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[23]
2006 | Journal Article | IST-REx-ID: 1961
Sazanov, Leonid A, and Philip Hinchliffe. “Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus Thermophilus.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1123809.
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[22]
2006 | Journal Article | IST-REx-ID: 1966
Hinchliffe, Philip, Joe Carroll, and Leonid A Sazanov. “Identification of a Novel Subunit of Respiratory Complex I from Thermus Thermophilus.” Biochemistry. ACS, 2006. https://doi.org/10.1021/bi0600998.
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[21]
2005 | Journal Article | IST-REx-ID: 1962
Hinchliffe, Philip, and Leonid A Sazanov. “Biochemistry: Organization of Iron-Sulfur Clusters in Respiratory Complex I.” Science. American Association for the Advancement of Science, 2005. https://doi.org/10.1126/science.1113988.
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[20]
2004 | Journal Article | IST-REx-ID: 1963
Mamedova, Aygun, Peter Holt, Joe Carroll, and Leonid A Sazanov. “Substrate-Induced Conformational Change in Bacterial Complex I.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2004. https://doi.org/10.1074/jbc.M401539200.
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[19]
2003 | Journal Article | IST-REx-ID: 1959
Holt, Peter, David Morgan, and Leonid A Sazanov. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M308247200.
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[18]
2003 | Journal Article | IST-REx-ID: 1960
Sazanov, Leonid A, Joe Carroll, Peter Holt, Laurence Toime, and Ian Fearnley. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M208959200.
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[17]
2000 | Journal Article | IST-REx-ID: 1957
Sazanov, Leonid A, and John Walker. “Cryo-Electron Crystallography of Two Sub-Complexes of Bovine Complex I Reveals the Relationship between the Membrane and Peripheral Arms.” Journal of Molecular Biology. Elsevier, 2000. https://doi.org/10.1006/jmbi.2000.4079.
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[16]
2000 | Journal Article | IST-REx-ID: 1958
Sazanov, Leonid A, Sew Peak Chew, Ian Fearnley, and John Walker. “Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme.” Biochemistry. ACS, 2000. https://doi.org/10.1021/bi000335t.
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[15]
1998 | Journal Article | IST-REx-ID: 1956 | OA
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “The Plastid Ndh Genes Code for an NADH-Specific Dehydrogenase: Isolation of a Complex I Analogue from Pea Thylakoid Membranes.” PNAS. National Academy of Sciences, 1998. https://doi.org/10.1073/pnas.95.3.1319.
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[14]
1998 | Journal Article | IST-REx-ID: 1955 | OA
Burrows, Paul, Leonid A Sazanov, Zóra Sváb, Pàl Maliga, and Peter Nixon. “Identification of a Functional Respiratory Complex in Chloroplasts through Analysis of Tobacco Mutants Containing Disrupted Plastid Ndh Genes.” EMBO Journal. Wiley-Blackwell, 1998. https://doi.org/10.1093/emboj/17.4.868.
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[13]
1998 | Journal Article | IST-REx-ID: 1954
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “The Chloroplast Ndh Complex Mediates the Dark Reduction of the Plastoquinone Pool in Response to Heat Stress in Tobacco Leaves.” FEBS Letters. Elsevier, 1998. https://doi.org/10.1016/S0014-5793(98)00573-0.
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[12]
1996 | Conference Paper | IST-REx-ID: 1942
Sazanov, Leonid A, P Burrows, and P J Nixon. “Presence of a Large Protein Complex Containing the NdhK Gene Product and Possessing NADH-Specific Dehydrogenase Activity in Thylakoid Membranes of Higher Plant Chloroplasts,” 2:705–8. Kluwer, 1996.
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[11]
1996 | Journal Article | IST-REx-ID: 1952
Bizouarn, Tania, Leonid A Sazanov, Sébastien Aubourg, and Julie Jackson. “Estimation of the H+/H- Ratio of the Reaction Catalysed by the Nicotinamide Nucleotide Transhydrogenase in Chromatophores from over-Expressing Strains of Rhodospirillum Rubrum and in Liposomes Inlaid with the Purified Bovine Enzyme.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1996. https://doi.org/10.1016/0005-2728(95)00125-5.
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[10]
1996 | Journal Article | IST-REx-ID: 1951
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “Detection and Characterization of a Complex I-like NADH-Specific Dehydrogenase from Pea Thylakoids.” Biochemical Society Transactions. Portland Press, 1996. https://doi.org/10.1042/bst0240739.
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[9]
1995 | Journal Article | IST-REx-ID: 1943 | OA
Sazanov, Leonid A, and Baz Jackson. “Cyclic Reactions Catalysed by Detergent-Dispersed and Reconstituted Transhydrogenase from Beef Heart Mitochondria; Implications for the Mechanism of Proton Translocation.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1995. https://doi.org/10.1016/0005-2728(95)00096-2.
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[8]
1994 | Journal Article | IST-REx-ID: 1949 | OA
Sazanov, Leonid A, and Julie Jackson. “Proton Translocating Transhydrogenase and NAD- and NADP-Linked Isocitrate Dehydrogenases Operate in a Substrate Cycle Which Contributes to Fine Regulation of the Tricarboxylic Acid Cycle Activity in Mitochondria.” FEBS Letters. Elsevier, 1994. https://doi.org/10.1016/0014-5793(94)00370-X.
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[7]
1994 | Journal Article | IST-REx-ID: 1953 | OA
Efanov, Alexander, Aleksei Koshkin, Leonid A Sazanov, O I Borodulina, Sergei Varfolomeev, and Sergei Zaǐtsev. “Inhibition of the Respiratory Burst in Mouse Macrophages by Ultra-Low Doses of an Opioid Peptide Is Consistent with a Possible Adaptation Mechanism.” FEBS Letters. Elsevier, 1994. https://doi.org/10.1016/0014-5793(94)01109-5.
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[6]
1993 | Journal Article | IST-REx-ID: 1947
Sazanov, Leonid A, and Julie Jackson. “Activation and Inhibition of Mitochondrial Transhydrogenase by Metal Ions.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1993. https://doi.org/10.1016/0005-2728(93)90177-H.
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[5]
1993 | Journal Article | IST-REx-ID: 1948
Sazanov, Leonid A, and Julie Jackson. “Possible Functions of the NADP-Linked Isocitrate Dehydrogenase and H+ -Transhydrogenase in Heart Mitochondria .” Biochemical Society Transactions. Portland Press, 1993. https://doi.org/10.1042/bst021260s.
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[4]
1993 | Journal Article | IST-REx-ID: 1950
Jackson, Julie, N P J Cotton, Ross Williams, Tania Bizouarn, Mike Hutton, Leonid A Sazanov, and Christopher Thomas. “Proton-Translocating Transhydrogenase in Bacteria.” Biochemical Society Transactions. Portland Press, 1993. https://doi.org/10.1042/bst0211010.
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[3]
1992 | Journal Article | IST-REx-ID: 1945
Sazanov, Leonid A, and Sergei Zaǐtsev. “Effect of Superlow Doses (10(-18)-10-(-14) M) of Biologically Active Substances: General Rules, Features, and Possible Mechanisms.” Biochemistry (Moscow). Izdatel’stvo Nauka, 1992.
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[2]
1991 | Journal Article | IST-REx-ID: 1946
Zaǐtsev, Sergei, Leonid A Sazanov, Aleksei Koshkin, Galina Sud’Ina, and Sergei Varfolomeev. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters. Elsevier, 1991. https://doi.org/10.1016/0014-5793(91)81109-L.
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[1]
1988 | Journal Article | IST-REx-ID: 1941
Sazanov, Leonid A, V A Karavaev, and A K Kukushkin. “Mathematical model of photosynthesis regulation accounts for the effects of changes in external conditions and observed oscillations.” Russian Journal of Physical Chemistry B. Elsevier, 1988.
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[73]
2024 | Journal Article | IST-REx-ID: 15323
Vercellino, Irene, and Leonid A Sazanov. “SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes.” Nature Structural and Molecular Biology. Springer Nature, 2024. https://doi.org/10.1038/s41594-024-01255-0.
View | DOI | PubMed | Europe PMC
 
[72]
2023 | Journal Article | IST-REx-ID: 12757 | OA
Sazanov, Leonid A. “From the ‘black Box’ to ‘Domino Effect’ Mechanism: What Have We Learned from the Structures of Respiratory Complex I.” The Biochemical Journal. Portland Press, 2023. https://doi.org/10.1042/BCJ20210285.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[71]
2023 | Journal Article | IST-REx-ID: 14040 | OA
Zhao, Ziyu, Irene Vercellino, Jana Knoppová, Roman Sobotka, James W. Murray, Peter J. Nixon, Leonid A Sazanov, and Josef Komenda. “The Ycf48 Accessory Factor Occupies the Site of the Oxygen-Evolving Manganese Cluster during Photosystem II Biogenesis.” Nature Communications. Springer Nature, 2023. https://doi.org/10.1038/s41467-023-40388-6.
[Published Version] View | Files available | DOI | WoS
 
[70]
2022 | Journal Article | IST-REx-ID: 10182
Vercellino, Irene, and Leonid A Sazanov. “The Assembly, Regulation and Function of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular Cell Biology. Springer Nature, 2022. https://doi.org/10.1038/s41580-021-00415-0.
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[69]
2022 | Journal Article | IST-REx-ID: 11167 | OA
Kampjut, Domen, and Leonid A Sazanov. “Structure of Respiratory Complex I – An Emerging Blueprint for the Mechanism.” Current Opinion in Structural Biology. Elsevier, 2022. https://doi.org/10.1016/j.sbi.2022.102350.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[68]
2022 | Journal Article | IST-REx-ID: 11551 | OA
Molina-Granada, David, Emiliano González-Vioque, Marris G. Dibley, Raquel Cabrera-Pérez, Antoni Vallbona-Garcia, Javier Torres-Torronteras, Leonid A Sazanov, Michael T. Ryan, Yolanda Cámara, and Ramon Martí. “Most Mitochondrial DGTP Is Tightly Bound to Respiratory Complex I through the NDUFA10 Subunit.” Communications Biology. Springer Nature, 2022. https://doi.org/10.1038/s42003-022-03568-6.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[67]
2022 | Journal Article | IST-REx-ID: 12138 | OA
Kravchuk, Vladyslav, Olga Petrova, Domen Kampjut, Anna Wojciechowska-Bason, Zara Breese, and Leonid A Sazanov. “A Universal Coupling Mechanism of Respiratory Complex I.” Nature. Springer Nature, 2022. https://doi.org/10.1038/s41586-022-05199-7.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[66]
2021 | Journal Article | IST-REx-ID: 8993 | OA
Abas, Lindy, Martina Kolb, Johannes Stadlmann, Dorina P. Janacek, Kristina Lukic, Claus Schwechheimer, Leonid A Sazanov, Lukas Mach, Jiří Friml, and Ulrich Z. Hammes. “Naphthylphthalamic Acid Associates with and Inhibits PIN Auxin Transporters.” PNAS. National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.2020857118.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[65]
2021 | Journal Article | IST-REx-ID: 9205 | OA
Kampjut, Domen, Julia Steiner, and Leonid A Sazanov. “Cryo-EM Grid Optimization for Membrane Proteins.” IScience. Elsevier, 2021. https://doi.org/10.1016/j.isci.2021.102139.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[64]
2021 | Journal Article | IST-REx-ID: 10146
Vercellino, Irene, and Leonid A Sazanov. “Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV.” Nature. Springer Nature, 2021. https://doi.org/10.1038/s41586-021-03927-z.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[63]
2020 | Journal Article | IST-REx-ID: 7788 | OA
Adjobo-Hermans, Merel J.W., Ria De Haas, Peter H.G.M. Willems, Aleksandra Wojtala, Sjenet E. Van Emst-De Vries, Jori A. Wagenaars, Mariel Van Den Brand, et al. “NDUFS4 Deletion Triggers Loss of NDUFA12 in Ndufs4−/− Mice and Leigh Syndrome Patients: A Stabilizing Role for NDUFAF2.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2020. https://doi.org/10.1016/j.bbabio.2020.148213.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[62]
2020 | Journal Article | IST-REx-ID: 8040
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M. R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I.” Journal of the American Chemical Society. American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.
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[61]
2020 | Research Data Reference | IST-REx-ID: 9326 | OA
Gupta, Chitrak, Umesh Khaniya, Chun Chan, Francois Dehez, Mrinal Shekhar, M. R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I.” American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
[60]
2020 | Research Data Reference | IST-REx-ID: 9713
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Supporting Information.” American Chemical Society , 2020. https://doi.org/10.1021/jacs.9b13450.s001.
[Published Version] View | Files available | DOI
 
[59]
2020 | Research Data Reference | IST-REx-ID: 9878
Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Movies.” American Chemical Society, 2020. https://doi.org/10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[58]
2020 | Journal Article | IST-REx-ID: 8318 | OA
Gutierrez-Fernandez, Javier, Karol Kaszuba, Gurdeep S. Minhas, Rozbeh Baradaran, Margherita Tambalo, David T. Gallagher, and Leonid A Sazanov. “Key Role of Quinone in the Mechanism of Respiratory Complex I.” Nature Communications. Springer Nature, 2020. https://doi.org/10.1038/s41467-020-17957-0.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[57]
2020 | Journal Article | IST-REx-ID: 8581
Pinke, Gergely, Long Zhou, and Leonid A Sazanov. “Cryo-EM Structure of the Entire Mammalian F-Type ATP Synthase.” Nature Structural and Molecular Biology. Springer Nature, 2020. https://doi.org/10.1038/s41594-020-0503-8.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[56]
2020 | Journal Article | IST-REx-ID: 8737 | OA
Kampjut, Domen, and Leonid A Sazanov. “The Coupling Mechanism of Mammalian Respiratory Complex I.” Science. American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.abc4209.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[55]
2020 | Journal Article | IST-REx-ID: 8284 | OA
Steiner, Julia, and Leonid A Sazanov. “Structure and Mechanism of the Mrp Complex, an Ancient Cation/Proton Antiporter.” ELife. eLife Sciences Publications, 2020. https://doi.org/10.7554/eLife.59407.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[54]
2019 | Journal Article | IST-REx-ID: 6859
Zhou, Long, and Leonid A Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science. AAAS, 2019. https://doi.org/10.1126/science.aaw9144.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[53]
2019 | Journal Article | IST-REx-ID: 7395 | OA
Letts, James A, Karol Fiedorczuk, Gianluca Degliesposti, Mark Skehel, and Leonid A Sazanov. “Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk.” Molecular Cell. Cell Press, 2019. https://doi.org/10.1016/j.molcel.2019.07.022.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[52]
2019 | Journal Article | IST-REx-ID: 6848 | OA
Kampjut, Domen, and Leonid A Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” Nature. Springer Nature, 2019. https://doi.org/10.1038/s41586-019-1519-2.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[51]
2018 | Journal Article | IST-REx-ID: 152 | OA
Fiedorczuk, Karol, and Leonid A Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” Trends in Cell Biology. Elsevier, 2018. https://doi.org/10.1016/j.tcb.2018.06.006.
[Submitted Version] View | Files available | DOI | WoS
 
[50]
2017 | Journal Article | IST-REx-ID: 443 | OA
Hardie, Rae, Ellen Van Dam, Mark Cowley, Ting Han, Seher Balaban, Marina Pajic, Mark Pinese, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism. BioMed Central, 2017. https://doi.org/10.1186/s40170-017-0164-1.
[Published Version] View | Files available | DOI
 
[49]
2017 | Book Chapter | IST-REx-ID: 444
Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” In Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, 25–59. Mechanisms of Primary Energy Transduction in Biology . Royal Society of Chemistry, 2017. https://doi.org/10.1039/9781788010405-00025.
View | DOI
 
[48]
2017 | Journal Article | IST-REx-ID: 515 | OA
Letts, James A, and Leonid A Sazanov. “Clarifying the Supercomplex: The Higher-Order Organization of the Mitochondrial Electron Transport Chain.” Nature Structural and Molecular Biology. Nature Publishing Group, 2017. https://doi.org/10.1038/nsmb.3460.
[Submitted Version] View | Files available | DOI
 
[47]
2016 | Journal Article | IST-REx-ID: 1209 | OA
Letts, James A, Gianluca Degliesposti, Karol Fiedorczuk, Mark Skehel, and Leonid A Sazanov. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2016. https://doi.org/10.1074/jbc.M116.735142.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
[46]
2016 | Journal Article | IST-REx-ID: 1226 | OA
Fiedorczuk, Karol, James A Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel, and Leonid A Sazanov. “Atomic Structure of the Entire Mammalian Mitochondrial Complex I.” Nature. Nature Publishing Group, 2016. https://doi.org/10.1038/nature19794.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[45]
2016 | Journal Article | IST-REx-ID: 1232
Letts, James A, Karol Fiedorczuk, and Leonid A Sazanov. “The Architecture of Respiratory Supercomplexes.” Nature. Nature Publishing Group, 2016. https://doi.org/10.1038/nature19774.
View | DOI
 
[44]
2016 | Journal Article | IST-REx-ID: 1288
Holt, Peter, Rouslan Efremov, Eiko Nakamaru Ogiso, and Leonid A Sazanov. “Reversible FMN Dissociation from Escherichia Coli Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2016. https://doi.org/10.1016/j.bbabio.2016.08.008.
View | DOI
 
[43]
2016 | Journal Article | IST-REx-ID: 1521
Berrisford, John, Rozbeh Baradaran, and Leonid A Sazanov. “Structure of Bacterial Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2016. https://doi.org/10.1016/j.bbabio.2016.01.012.
View | DOI
 
[42]
2015 | Journal Article | IST-REx-ID: 1638
Sazanov, Leonid A. “A Giant Molecular Proton Pump: Structure and Mechanism of Respiratory Complex I.” Nature Reviews Molecular Cell Biology. Nature Publishing Group, 2015. https://doi.org/10.1038/nrm3997.
View | DOI
 
[41]
2015 | Journal Article | IST-REx-ID: 1683
Letts, James A, and Leonid A Sazanov. “Gaining Mass: The Structure of Respiratory Complex I-from Bacterial towards Mitochondrial Versions.” Current Opinion in Structural Biology. Elsevier, 2015. https://doi.org/10.1016/j.sbi.2015.08.008.
View | DOI
 
[40]
2014 | Book Review | IST-REx-ID: 1981
Garvin, Michael, Joseph Bielawski, Leonid A Sazanov, and Anthony Gharrett. “Review and Meta-Analysis of Natural Selection in Mitochondrial Complex I in Metazoans.” Journal of Zoological Systematics and Evolutionary Research. Wiley-Blackwell, 2014. https://doi.org/10.1111/jzs.12079.
View | DOI
 
[39]
2014 | Journal Article | IST-REx-ID: 1980
Heikal, Adam, Yoshio Nakatani, Elyse Dunn, Marion Weimar, Catherine Day, Edward Baker, Shaun Lott, Leonid A Sazanov, and Gregory Cook. “Structure of the Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular Microbiology. Wiley-Blackwell, 2014. https://doi.org/10.1111/mmi.12507.
View | DOI
 
[38]
2014 | Journal Article | IST-REx-ID: 1979
Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer and Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics and Biomembranes. Springer, 2014. https://doi.org/10.1007/s10863-014-9554-z.
View | DOI
 
[37]
2013 | Journal Article | IST-REx-ID: 1977
Sazanov, Leonid A, Rozbeh Baradaran, Rouslan Efremov, John Berrisford, and Gurdeep Minhas. “A Long Road towards the Structure of Respiratory Complex I, a Giant Molecular Proton Pump.” Biochemical Society Transactions. Portland Press, 2013. https://doi.org/10.1042/BST20130193.
View | DOI
 
[36]
2013 | Journal Article | IST-REx-ID: 1978
Baradaran, Rozbeh, John Berrisford, Gurdeep Minhas, and Leonid A Sazanov. “Crystal Structure of the Entire Respiratory Complex I.” Nature. Nature Publishing Group, 2013. https://doi.org/10.1038/nature11871.
View | DOI
 
[35]
2012 | Book Review | IST-REx-ID: 1976
Efremov, Rouslan, and Leonid A Sazanov. “The Coupling Mechanism of Respiratory Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2012. https://doi.org/10.1016/j.bbabio.2012.02.015.
View | DOI
 
[34]
2012 | Journal Article | IST-REx-ID: 1972
Efremov, Rouslan, and Leonid A Sazanov. “Structure of Escherichia Coli OmpF Porin from Lipidic Mesophase.” Journal of Structural Biology. Academic Press, 2012. https://doi.org/10.1016/j.jsb.2012.03.005.
View | DOI
 
[33]
2011 | Journal Article | IST-REx-ID: 1975
Yip, Chui, Michael Harbour, Kamburapola Jayawardena, Ian Fearnley, and Leonid A Sazanov. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2011. https://doi.org/10.1074/jbc.M110.194993.
View | DOI
 
[32]
2011 | Journal Article | IST-REx-ID: 1973
Efremov, Rouslan, and Leonid A Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature. Nature Publishing Group, 2011. https://doi.org/10.1038/nature10330.
View | DOI
 
[31]
2011 | Journal Article | IST-REx-ID: 1974
Efremov, Rouslan, and Leonid A Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology. Elsevier, 2011. https://doi.org/10.1016/j.sbi.2011.07.002.
View | DOI
 
[30]
2010 | Journal Article | IST-REx-ID: 1970
Efremov, Rouslan, Rozbeh Baradaran, and Leonid A Sazanov. “The Architecture of Respiratory Complex I.” Nature. Nature Publishing Group, 2010. https://doi.org/10.1038/nature09066.
View | DOI
 
[29]
2009 | Journal Article | IST-REx-ID: 1971
Berrisford, John, and Leonid A Sazanov. “Structural Basis for the Mechanism of Respiratory Complex I.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2009. https://doi.org/10.1074/jbc.M109.032144.
View | DOI
 
[28]
2008 | Journal Article | IST-REx-ID: 1967
Berrisford, John, Christopher Thompson, and Leonid A Sazanov. “Chemical and NADH-Induced, ROS-Dependent, Cross-Linking between Sublimits of Complex I from Escherichia Coli and Thermus Thermophilus.” Biochemistry. ACS, 2008. https://doi.org/10.1021/bi801160u.
View | DOI
 
[27]
2008 | Journal Article | IST-REx-ID: 1968
Morgan, David, and Leonid A Sazanov. “Three-Dimensional Structure of Respiratory Complex I from Escherichia Coli in Ice in the Presence of Nucleotides.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 2008. https://doi.org/10.1016/j.bbabio.2008.03.023.
View | DOI
 
[26]
2007 | Journal Article | IST-REx-ID: 1965
Baranova, Ekaterina, Peter Holt, and Leonid A Sazanov. “Projection Structure of the Membrane Domain of Escherichia Coli Respiratory Complex I at 8 Å Resolution.” Journal of Molecular Biology. Elsevier, 2007. https://doi.org/10.1016/j.jmb.2006.11.026.
View | DOI
 
[25]
2007 | Journal Article | IST-REx-ID: 1969
Baranova, Ekaterina, David Morgan, and Leonid A Sazanov. “Single Particle Analysis Confirms Distal Location of Subunits NuoL and NuoM in Escherichia Coli Complex I.” Journal of Structural Biology. Academic Press, 2007. https://doi.org/10.1016/j.jsb.2007.01.009.
View | DOI
 
[24]
2007 | Journal Article | IST-REx-ID: 1964
Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural Insights Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry. ACS, 2007. https://doi.org/10.1021/bi602508x.
View | DOI
 
[23]
2006 | Journal Article | IST-REx-ID: 1961
Sazanov, Leonid A, and Philip Hinchliffe. “Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus Thermophilus.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1123809.
View | DOI
 
[22]
2006 | Journal Article | IST-REx-ID: 1966
Hinchliffe, Philip, Joe Carroll, and Leonid A Sazanov. “Identification of a Novel Subunit of Respiratory Complex I from Thermus Thermophilus.” Biochemistry. ACS, 2006. https://doi.org/10.1021/bi0600998.
View | DOI
 
[21]
2005 | Journal Article | IST-REx-ID: 1962
Hinchliffe, Philip, and Leonid A Sazanov. “Biochemistry: Organization of Iron-Sulfur Clusters in Respiratory Complex I.” Science. American Association for the Advancement of Science, 2005. https://doi.org/10.1126/science.1113988.
View | DOI
 
[20]
2004 | Journal Article | IST-REx-ID: 1963
Mamedova, Aygun, Peter Holt, Joe Carroll, and Leonid A Sazanov. “Substrate-Induced Conformational Change in Bacterial Complex I.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2004. https://doi.org/10.1074/jbc.M401539200.
View | DOI
 
[19]
2003 | Journal Article | IST-REx-ID: 1959
Holt, Peter, David Morgan, and Leonid A Sazanov. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M308247200.
View | DOI
 
[18]
2003 | Journal Article | IST-REx-ID: 1960
Sazanov, Leonid A, Joe Carroll, Peter Holt, Laurence Toime, and Ian Fearnley. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M208959200.
View | DOI
 
[17]
2000 | Journal Article | IST-REx-ID: 1957
Sazanov, Leonid A, and John Walker. “Cryo-Electron Crystallography of Two Sub-Complexes of Bovine Complex I Reveals the Relationship between the Membrane and Peripheral Arms.” Journal of Molecular Biology. Elsevier, 2000. https://doi.org/10.1006/jmbi.2000.4079.
View | DOI | PubMed | Europe PMC
 
[16]
2000 | Journal Article | IST-REx-ID: 1958
Sazanov, Leonid A, Sew Peak Chew, Ian Fearnley, and John Walker. “Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme.” Biochemistry. ACS, 2000. https://doi.org/10.1021/bi000335t.
View | DOI | PubMed | Europe PMC
 
[15]
1998 | Journal Article | IST-REx-ID: 1956 | OA
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “The Plastid Ndh Genes Code for an NADH-Specific Dehydrogenase: Isolation of a Complex I Analogue from Pea Thylakoid Membranes.” PNAS. National Academy of Sciences, 1998. https://doi.org/10.1073/pnas.95.3.1319.
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[14]
1998 | Journal Article | IST-REx-ID: 1955 | OA
Burrows, Paul, Leonid A Sazanov, Zóra Sváb, Pàl Maliga, and Peter Nixon. “Identification of a Functional Respiratory Complex in Chloroplasts through Analysis of Tobacco Mutants Containing Disrupted Plastid Ndh Genes.” EMBO Journal. Wiley-Blackwell, 1998. https://doi.org/10.1093/emboj/17.4.868.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[13]
1998 | Journal Article | IST-REx-ID: 1954
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “The Chloroplast Ndh Complex Mediates the Dark Reduction of the Plastoquinone Pool in Response to Heat Stress in Tobacco Leaves.” FEBS Letters. Elsevier, 1998. https://doi.org/10.1016/S0014-5793(98)00573-0.
View | DOI | PubMed | Europe PMC
 
[12]
1996 | Conference Paper | IST-REx-ID: 1942
Sazanov, Leonid A, P Burrows, and P J Nixon. “Presence of a Large Protein Complex Containing the NdhK Gene Product and Possessing NADH-Specific Dehydrogenase Activity in Thylakoid Membranes of Higher Plant Chloroplasts,” 2:705–8. Kluwer, 1996.
View
 
[11]
1996 | Journal Article | IST-REx-ID: 1952
Bizouarn, Tania, Leonid A Sazanov, Sébastien Aubourg, and Julie Jackson. “Estimation of the H+/H- Ratio of the Reaction Catalysed by the Nicotinamide Nucleotide Transhydrogenase in Chromatophores from over-Expressing Strains of Rhodospirillum Rubrum and in Liposomes Inlaid with the Purified Bovine Enzyme.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1996. https://doi.org/10.1016/0005-2728(95)00125-5.
View | DOI | PubMed | Europe PMC
 
[10]
1996 | Journal Article | IST-REx-ID: 1951
Sazanov, Leonid A, Paul Burrows, and Peter Nixon. “Detection and Characterization of a Complex I-like NADH-Specific Dehydrogenase from Pea Thylakoids.” Biochemical Society Transactions. Portland Press, 1996. https://doi.org/10.1042/bst0240739.
View | DOI | PubMed | Europe PMC
 
[9]
1995 | Journal Article | IST-REx-ID: 1943 | OA
Sazanov, Leonid A, and Baz Jackson. “Cyclic Reactions Catalysed by Detergent-Dispersed and Reconstituted Transhydrogenase from Beef Heart Mitochondria; Implications for the Mechanism of Proton Translocation.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1995. https://doi.org/10.1016/0005-2728(95)00096-2.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
1994 | Journal Article | IST-REx-ID: 1949 | OA
Sazanov, Leonid A, and Julie Jackson. “Proton Translocating Transhydrogenase and NAD- and NADP-Linked Isocitrate Dehydrogenases Operate in a Substrate Cycle Which Contributes to Fine Regulation of the Tricarboxylic Acid Cycle Activity in Mitochondria.” FEBS Letters. Elsevier, 1994. https://doi.org/10.1016/0014-5793(94)00370-X.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[7]
1994 | Journal Article | IST-REx-ID: 1953 | OA
Efanov, Alexander, Aleksei Koshkin, Leonid A Sazanov, O I Borodulina, Sergei Varfolomeev, and Sergei Zaǐtsev. “Inhibition of the Respiratory Burst in Mouse Macrophages by Ultra-Low Doses of an Opioid Peptide Is Consistent with a Possible Adaptation Mechanism.” FEBS Letters. Elsevier, 1994. https://doi.org/10.1016/0014-5793(94)01109-5.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[6]
1993 | Journal Article | IST-REx-ID: 1947
Sazanov, Leonid A, and Julie Jackson. “Activation and Inhibition of Mitochondrial Transhydrogenase by Metal Ions.” Biochimica et Biophysica Acta - Bioenergetics. Elsevier, 1993. https://doi.org/10.1016/0005-2728(93)90177-H.
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[5]
1993 | Journal Article | IST-REx-ID: 1948
Sazanov, Leonid A, and Julie Jackson. “Possible Functions of the NADP-Linked Isocitrate Dehydrogenase and H+ -Transhydrogenase in Heart Mitochondria .” Biochemical Society Transactions. Portland Press, 1993. https://doi.org/10.1042/bst021260s.
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[4]
1993 | Journal Article | IST-REx-ID: 1950
Jackson, Julie, N P J Cotton, Ross Williams, Tania Bizouarn, Mike Hutton, Leonid A Sazanov, and Christopher Thomas. “Proton-Translocating Transhydrogenase in Bacteria.” Biochemical Society Transactions. Portland Press, 1993. https://doi.org/10.1042/bst0211010.
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[3]
1992 | Journal Article | IST-REx-ID: 1945
Sazanov, Leonid A, and Sergei Zaǐtsev. “Effect of Superlow Doses (10(-18)-10-(-14) M) of Biologically Active Substances: General Rules, Features, and Possible Mechanisms.” Biochemistry (Moscow). Izdatel’stvo Nauka, 1992.
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[2]
1991 | Journal Article | IST-REx-ID: 1946
Zaǐtsev, Sergei, Leonid A Sazanov, Aleksei Koshkin, Galina Sud’Ina, and Sergei Varfolomeev. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters. Elsevier, 1991. https://doi.org/10.1016/0014-5793(91)81109-L.
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[1]
1988 | Journal Article | IST-REx-ID: 1941
Sazanov, Leonid A, V A Karavaev, and A K Kukushkin. “Mathematical model of photosynthesis regulation accounts for the effects of changes in external conditions and observed oscillations.” Russian Journal of Physical Chemistry B. Elsevier, 1988.
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