Leonid A Sazanov

Sazanov Group

75 Publications

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[75]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 18987 | OA
Kaiyrzhanov R, Thompson K, Efthymiou S, Mukushev A, Zharylkassyn A, Prasad C, Karimiani EG, Alvi JR, Niyazov D, Alahmad A, Babaei M, Tajsharghi H, Albash B, Alaqeel A, Charif M, Hashemi N, Heidari M, Kalantar SM, Lenaers G, Mehrjardi MYV, Srinivasan VM, Gowda VK, Mirabutalebi SH, Carere DA, Movahedinia M, Murphy D, Mcfarland R, Abdel-Hamid MS, Elhossini RM, Alavi S, Napier M, Belanger-Quintana A, Prasad AN, Jakobczyk J, Roubertie A, Rupar T, Sultan T, Toosi MB, Sazanov LA, Severino M, Houlden H, Taylor RW, Maroofian R. 2025. Biallelic NDUFA13 variants lead to a neurodevelopmental phenotype with gradual neurological impairment. Brain Communications. 7(1), fcae453.
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[74]
2024 | Published | Other Publication | IST-REx-ID: 18967 | OA
Petrova, Olga, et al. “Structure‐activity Relationship Study of Neuroprotective Complex I Inhibitor CP2.” Alzheimer’s & Dementia, vol. 20, no. S6, e085971, Wiley, 2024, doi:10.1002/alz.085971.
[Published Version] View | Files available | DOI
 
[73]
2024 | Published | Journal Article | IST-REx-ID: 15323 | OA
Vercellino, Irene, and Leonid A. Sazanov. “SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes.” Nature Structural and Molecular Biology, vol. 31, Springer Nature, 2024, pp. 1061–71, doi:10.1038/s41594-024-01255-0.
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[72]
2023 | Published | Journal Article | IST-REx-ID: 12757 | OA
Sazanov, Leonid A. “From the ‘black Box’ to ‘Domino Effect’ Mechanism: What Have We Learned from the Structures of Respiratory Complex I.” The Biochemical Journal, vol. 480, no. 5, Portland Press, 2023, pp. 319–33, doi:10.1042/BCJ20210285.
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[71]
2023 | Published | Journal Article | IST-REx-ID: 14040 | OA
Zhao, Ziyu, et al. “The Ycf48 Accessory Factor Occupies the Site of the Oxygen-Evolving Manganese Cluster during Photosystem II Biogenesis.” Nature Communications, vol. 14, 4681, Springer Nature, 2023, doi:10.1038/s41467-023-40388-6.
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[70]
2022 | Published | Journal Article | IST-REx-ID: 11167 | OA
Kampjut, Domen, and Leonid A. Sazanov. “Structure of Respiratory Complex I – An Emerging Blueprint for the Mechanism.” Current Opinion in Structural Biology, vol. 74, 102350, Elsevier, 2022, doi:10.1016/j.sbi.2022.102350.
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[69]
2022 | Published | Journal Article | IST-REx-ID: 11551 | OA
Molina-Granada, David, et al. “Most Mitochondrial DGTP Is Tightly Bound to Respiratory Complex I through the NDUFA10 Subunit.” Communications Biology, vol. 5, no. 1, 620, Springer Nature, 2022, doi:10.1038/s42003-022-03568-6.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[68]
2022 | Published | Journal Article | IST-REx-ID: 10182
Vercellino, Irene, and Leonid A. Sazanov. “The Assembly, Regulation and Function of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular Cell Biology, vol. 23, Springer Nature, 2022, pp. 141–161, doi:10.1038/s41580-021-00415-0.
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[67]
2022 | Published | Journal Article | IST-REx-ID: 12138 | OA
Kravchuk, Vladyslav, et al. “A Universal Coupling Mechanism of Respiratory Complex I.” Nature, vol. 609, no. 7928, Springer Nature, 2022, pp. 808–14, doi:10.1038/s41586-022-05199-7.
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[66]
2021 | Published | Journal Article | IST-REx-ID: 9205 | OA
Kampjut, Domen, et al. “Cryo-EM Grid Optimization for Membrane Proteins.” IScience, vol. 24, no. 3, 102139, Elsevier, 2021, doi:10.1016/j.isci.2021.102139.
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[65]
2021 | Published | Journal Article | IST-REx-ID: 10146
Vercellino, Irene, and Leonid A. Sazanov. “Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV.” Nature, vol. 598, no. 7880, Springer Nature, 2021, pp. 364–67, doi:10.1038/s41586-021-03927-z.
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[64]
2021 | Published | Journal Article | IST-REx-ID: 8993 | OA
Abas, Lindy, Naphthylphthalamic acid associates with and inhibits PIN auxin transporters. Proceedings of the National Academy of Sciences of the United States of America 118 (1). 2021
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[63]
2020 | Published | Journal Article | IST-REx-ID: 8318 | OA
Gutierrez-Fernandez, Javier, et al. “Key Role of Quinone in the Mechanism of Respiratory Complex I.” Nature Communications, vol. 11, no. 1, 4135, Springer Nature, 2020, doi:10.1038/s41467-020-17957-0.
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[62]
2020 | Published | Journal Article | IST-REx-ID: 8040
Gupta, Chitrak, Charge transfer and chemo-mechanical coupling in respiratory complex I. Journal of the American Chemical Society 142 (20). 2020
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[61]
2020 | Research Data Reference | IST-REx-ID: 9326
Gupta, Chitrak, et al. Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I. American Chemical Society, 2020, doi:10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[60]
2020 | Research Data Reference | IST-REx-ID: 9713
Gupta, Chitrak, et al. Supporting Information. American Chemical Society , 2020, doi:10.1021/jacs.9b13450.s001.
[Published Version] View | Files available | DOI
 
[59]
2020 | Research Data Reference | IST-REx-ID: 9878
Gupta, Chitrak, et al. Movies. American Chemical Society, 2020, doi:10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[58]
2020 | Published | Journal Article | IST-REx-ID: 7788 | OA
Adjobo-Hermans, Merel J.W., NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics 1861 (8). 2020
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[57]
2020 | Published | Journal Article | IST-REx-ID: 8581
Pinke, Gergely, Cryo-EM structure of the entire mammalian F-type ATP synthase. Nature Structural and Molecular Biology 27 (11). 2020
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[56]
2020 | Published | Journal Article | IST-REx-ID: 8737 | OA
Kampjut, Domen, and Leonid A. Sazanov. “The Coupling Mechanism of Mammalian Respiratory Complex I.” Science, vol. 370, no. 6516, eabc4209, American Association for the Advancement of Science, 2020, doi:10.1126/science.abc4209.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[55]
2020 | Published | Journal Article | IST-REx-ID: 8284 | OA
Steiner, Julia, and Leonid A. Sazanov. “Structure and Mechanism of the Mrp Complex, an Ancient Cation/Proton Antiporter.” ELife, vol. 9, e59407, eLife Sciences Publications, 2020, doi:10.7554/eLife.59407.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[54]
2019 | Published | Journal Article | IST-REx-ID: 6859
Zhou, Long, and Leonid A. Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science, vol. 365, no. 6455, eaaw9144, AAAS, 2019, doi:10.1126/science.aaw9144.
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[53]
2019 | Published | Journal Article | IST-REx-ID: 7395 | OA
Letts, James A., et al. “Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk.” Molecular Cell, vol. 75, no. 6, Cell Press, 2019, p. 1131–1146.e6, doi:10.1016/j.molcel.2019.07.022.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[52]
2019 | Published | Journal Article | IST-REx-ID: 6848 | OA
Kampjut, Domen, and Leonid A. Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” Nature, vol. 573, no. 7773, Springer Nature, 2019, pp. 291–295, doi:10.1038/s41586-019-1519-2.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[51]
2018 | Published | Journal Article | IST-REx-ID: 152 | OA
Fiedorczuk, Karol, and Leonid A. Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” Trends in Cell Biology, vol. 28, no. 10, Elsevier, 2018, pp. 835–67, doi:10.1016/j.tcb.2018.06.006.
[Submitted Version] View | Files available | DOI | WoS
 
[50]
2017 | Published | Journal Article | IST-REx-ID: 443 | OA
Hardie, Rae, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism, vol. 5, no. 2, BioMed Central, 2017, doi:10.1186/s40170-017-0164-1.
[Published Version] View | Files available | DOI
 
[49]
2017 | Published | Book Chapter | IST-REx-ID: 444
Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, Royal Society of Chemistry, 2017, pp. 25–59, doi:10.1039/9781788010405-00025.
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[48]
2017 | Published | Journal Article | IST-REx-ID: 515 | OA
Letts, James A, Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain. Nature Structural and Molecular Biology 24 (10). 2017
[Submitted Version] View | Files available | DOI
 
[47]
2016 | Published | Journal Article | IST-REx-ID: 1288
Holt, Peter, et al. “Reversible FMN Dissociation from Escherichia Coli Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1857, no. 11, Elsevier, 2016, pp. 1777–85, doi:10.1016/j.bbabio.2016.08.008.
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[46]
2016 | Published | Journal Article | IST-REx-ID: 1521
Berrisford, John, et al. “Structure of Bacterial Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1857, no. 7, Elsevier, 2016, pp. 892–901, doi:10.1016/j.bbabio.2016.01.012.
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[45]
2016 | Published | Journal Article | IST-REx-ID: 1209 | OA
Letts, James A., et al. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” Journal of Biological Chemistry, vol. 291, no. 47, American Society for Biochemistry and Molecular Biology, 2016, pp. 24657–75, doi:10.1074/jbc.M116.735142.
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[44]
2016 | Published | Journal Article | IST-REx-ID: 1226 | OA
Fiedorczuk, Karol, et al. “Atomic Structure of the Entire Mammalian Mitochondrial Complex I.” Nature, vol. 538, no. 7625, Nature Publishing Group, 2016, pp. 406–10, doi:10.1038/nature19794.
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[43]
2016 | Published | Journal Article | IST-REx-ID: 1232
Letts, James A., et al. “The Architecture of Respiratory Supercomplexes.” Nature, vol. 537, no. 7622, Nature Publishing Group, 2016, pp. 644–48, doi:10.1038/nature19774.
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[42]
2015 | Published | Journal Article | IST-REx-ID: 1683
Letts, James A., and Leonid A. Sazanov. “Gaining Mass: The Structure of Respiratory Complex I-from Bacterial towards Mitochondrial Versions.” Current Opinion in Structural Biology, vol. 33, no. 8, Elsevier, 2015, pp. 135–45, doi:10.1016/j.sbi.2015.08.008.
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[41]
2015 | Published | Journal Article | IST-REx-ID: 1638
Sazanov, Leonid A. “A Giant Molecular Proton Pump: Structure and Mechanism of Respiratory Complex I.” Nature Reviews Molecular Cell Biology, vol. 16, no. 6, Nature Publishing Group, 2015, pp. 375–88, doi:10.1038/nrm3997.
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[40]
2014 | Published | Journal Article | IST-REx-ID: 1979
Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer and Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics and Biomembranes, vol. 46, no. 4, Springer, 2014, pp. 247–53, doi:10.1007/s10863-014-9554-z.
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[39]
2014 | Published | Journal Article | IST-REx-ID: 1980
Heikal, Adam, et al. “Structure of the Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular Microbiology, vol. 91, no. 5, Wiley-Blackwell, 2014, pp. 950–64, doi:10.1111/mmi.12507.
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[38]
2014 | Published | Book Review | IST-REx-ID: 1981
Garvin, Michael, et al. “Review and Meta-Analysis of Natural Selection in Mitochondrial Complex I in Metazoans.” Journal of Zoological Systematics and Evolutionary Research, vol. 53, no. 1, Wiley-Blackwell, 2014, pp. 1–17, doi:10.1111/jzs.12079.
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[37]
2013 | Published | Journal Article | IST-REx-ID: 1977
Sazanov, Leonid A., et al. “A Long Road towards the Structure of Respiratory Complex I, a Giant Molecular Proton Pump.” Biochemical Society Transactions, vol. 41, no. 5, Portland Press, 2013, pp. 1265–71, doi:10.1042/BST20130193.
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[36]
2013 | Published | Journal Article | IST-REx-ID: 1978
Baradaran, Rozbeh, et al. “Crystal Structure of the Entire Respiratory Complex I.” Nature, vol. 494, no. 7438, Nature Publishing Group, 2013, pp. 443–48, doi:10.1038/nature11871.
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[35]
2012 | Published | Journal Article | IST-REx-ID: 1972
Efremov, Rouslan, and Leonid A. Sazanov. “Structure of Escherichia Coli OmpF Porin from Lipidic Mesophase.” Journal of Structural Biology, vol. 178, no. 3, Academic Press, 2012, pp. 311–18, doi:10.1016/j.jsb.2012.03.005.
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[34]
2012 | Published | Book Review | IST-REx-ID: 1976
Efremov, Rouslan, and Leonid A. Sazanov. “The Coupling Mechanism of Respiratory Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1817, no. 10, Elsevier, 2012, pp. 1785–95, doi:10.1016/j.bbabio.2012.02.015.
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[33]
2011 | Published | Journal Article | IST-REx-ID: 1973
Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature, vol. 476, no. 7361, Nature Publishing Group, 2011, pp. 414–21, doi:10.1038/nature10330.
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[32]
2011 | Published | Journal Article | IST-REx-ID: 1974
Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology, vol. 21, no. 4, Elsevier, 2011, pp. 532–40, doi:10.1016/j.sbi.2011.07.002.
View | DOI
 
[31]
2011 | Published | Journal Article | IST-REx-ID: 1975
Yip, Chui, et al. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry, vol. 286, no. 7, American Society for Biochemistry and Molecular Biology, 2011, pp. 5023–33, doi:10.1074/jbc.M110.194993.
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[30]
2010 | Published | Journal Article | IST-REx-ID: 1970
Efremov, Rouslan, et al. “The Architecture of Respiratory Complex I.” Nature, vol. 465, no. 7297, Nature Publishing Group, 2010, pp. 441–45, doi:10.1038/nature09066.
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[29]
2009 | Published | Journal Article | IST-REx-ID: 1971
Berrisford, John, and Leonid A. Sazanov. “Structural Basis for the Mechanism of Respiratory Complex I.” Journal of Biological Chemistry, vol. 284, no. 43, American Society for Biochemistry and Molecular Biology, 2009, pp. 29773–83, doi:10.1074/jbc.M109.032144.
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[28]
2008 | Published | Journal Article | IST-REx-ID: 1967
Berrisford, John, et al. “Chemical and NADH-Induced, ROS-Dependent, Cross-Linking between Sublimits of Complex I from Escherichia Coli and Thermus Thermophilus.” Biochemistry, vol. 47, no. 39, ACS, 2008, pp. 10262–70, doi:10.1021/bi801160u.
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[27]
2008 | Published | Journal Article | IST-REx-ID: 1968
Morgan, David, and Leonid A. Sazanov. “Three-Dimensional Structure of Respiratory Complex I from Escherichia Coli in Ice in the Presence of Nucleotides.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1777, no. 7–8, Elsevier, 2008, pp. 711–18, doi:10.1016/j.bbabio.2008.03.023.
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[26]
2007 | Published | Journal Article | IST-REx-ID: 1964
Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural Insights Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry, vol. 46, no. 9, ACS, 2007, pp. 2275–88, doi:10.1021/bi602508x.
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[25]
2007 | Published | Journal Article | IST-REx-ID: 1965
Baranova, Ekaterina, et al. “Projection Structure of the Membrane Domain of Escherichia Coli Respiratory Complex I at 8 Å Resolution.” Journal of Molecular Biology, vol. 366, no. 1, Elsevier, 2007, pp. 140–54, doi:10.1016/j.jmb.2006.11.026.
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[24]
2007 | Published | Journal Article | IST-REx-ID: 1969
Baranova, Ekaterina, et al. “Single Particle Analysis Confirms Distal Location of Subunits NuoL and NuoM in Escherichia Coli Complex I.” Journal of Structural Biology, vol. 159, no. 2 SPEC. ISS., Academic Press, 2007, pp. 238–42, doi:10.1016/j.jsb.2007.01.009.
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[23]
2006 | Published | Journal Article | IST-REx-ID: 1961
Sazanov, Leonid A., and Philip Hinchliffe. “Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus Thermophilus.” Science, vol. 311, no. 5766, American Association for the Advancement of Science, 2006, pp. 1430–36, doi:10.1126/science.1123809.
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[22]
2006 | Published | Journal Article | IST-REx-ID: 1966
Hinchliffe, Philip, et al. “Identification of a Novel Subunit of Respiratory Complex I from Thermus Thermophilus.” Biochemistry, vol. 45, no. 14, ACS, 2006, pp. 4413–20, doi:10.1021/bi0600998.
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[21]
2005 | Published | Journal Article | IST-REx-ID: 1962
Hinchliffe, Philip, and Leonid A. Sazanov. “Biochemistry: Organization of Iron-Sulfur Clusters in Respiratory Complex I.” Science, vol. 309, no. 5735, American Association for the Advancement of Science, 2005, pp. 771–74, doi:10.1126/science.1113988.
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[20]
2004 | Published | Journal Article | IST-REx-ID: 1963
Mamedova, Aygun, et al. “Substrate-Induced Conformational Change in Bacterial Complex I.” Journal of Biological Chemistry, vol. 279, no. 22, American Society for Biochemistry and Molecular Biology, 2004, pp. 23830–36, doi:10.1074/jbc.M401539200.
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[19]
2003 | Published | Journal Article | IST-REx-ID: 1959
Holt, Peter, et al. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry, vol. 278, no. 44, American Society for Biochemistry and Molecular Biology, 2003, pp. 43114–20, doi:10.1074/jbc.M308247200.
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[18]
2003 | Published | Journal Article | IST-REx-ID: 1960
Sazanov, Leonid A., et al. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry, vol. 278, no. 21, American Society for Biochemistry and Molecular Biology, 2003, pp. 19483–91, doi:10.1074/jbc.M208959200.
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[17]
2000 | Published | Journal Article | IST-REx-ID: 1957
Sazanov, Leonid A., and John Walker. “Cryo-Electron Crystallography of Two Sub-Complexes of Bovine Complex I Reveals the Relationship between the Membrane and Peripheral Arms.” Journal of Molecular Biology, vol. 302, no. 2, Elsevier, 2000, pp. 455–64, doi:10.1006/jmbi.2000.4079.
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[16]
2000 | Published | Journal Article | IST-REx-ID: 1958
Sazanov, Leonid A., et al. “Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme.” Biochemistry, vol. 39, no. 24, ACS, 2000, pp. 7229–35, doi:10.1021/bi000335t.
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[15]
1998 | Published | Journal Article | IST-REx-ID: 1954
Sazanov, Leonid A., et al. “The Chloroplast Ndh Complex Mediates the Dark Reduction of the Plastoquinone Pool in Response to Heat Stress in Tobacco Leaves.” FEBS Letters, vol. 429, no. 1, Elsevier, 1998, pp. 115–18, doi:10.1016/S0014-5793(98)00573-0.
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[14]
1998 | Published | Journal Article | IST-REx-ID: 1955 | OA
Burrows, Paul, et al. “Identification of a Functional Respiratory Complex in Chloroplasts through Analysis of Tobacco Mutants Containing Disrupted Plastid Ndh Genes.” EMBO Journal, vol. 17, no. 4, Wiley-Blackwell, 1998, pp. 868–76, doi:10.1093/emboj/17.4.868.
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[13]
1998 | Published | Journal Article | IST-REx-ID: 1956 | OA
Sazanov, Leonid A., et al. “The Plastid Ndh Genes Code for an NADH-Specific Dehydrogenase: Isolation of a Complex I Analogue from Pea Thylakoid Membranes.” PNAS, vol. 95, no. 3, National Academy of Sciences, 1998, pp. 1319–24, doi:10.1073/pnas.95.3.1319.
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[12]
1996 | Published | Conference Paper | IST-REx-ID: 1942
Sazanov, Leonid A., et al. Presence of a Large Protein Complex Containing the NdhK Gene Product and Possessing NADH-Specific Dehydrogenase Activity in Thylakoid Membranes of Higher Plant Chloroplasts. Vol. 2, Kluwer, 1996, pp. 705–08.
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[11]
1996 | Published | Journal Article | IST-REx-ID: 1951
Sazanov, Leonid A., et al. “Detection and Characterization of a Complex I-like NADH-Specific Dehydrogenase from Pea Thylakoids.” Biochemical Society Transactions, vol. 24, no. 3, Portland Press, 1996, pp. 739–43, doi:10.1042/bst0240739.
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[10]
1996 | Published | Journal Article | IST-REx-ID: 1952
Bizouarn, Tania, et al. “Estimation of the H+/H- Ratio of the Reaction Catalysed by the Nicotinamide Nucleotide Transhydrogenase in Chromatophores from over-Expressing Strains of Rhodospirillum Rubrum and in Liposomes Inlaid with the Purified Bovine Enzyme.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1273, no. 1, Elsevier, 1996, pp. 4–12, doi:10.1016/0005-2728(95)00125-5.
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[9]
1995 | Published | Journal Article | IST-REx-ID: 1943 | OA
Sazanov, Leonid A., and Baz Jackson. “Cyclic Reactions Catalysed by Detergent-Dispersed and Reconstituted Transhydrogenase from Beef Heart Mitochondria; Implications for the Mechanism of Proton Translocation.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1231, no. 3, Elsevier, 1995, pp. 304–12, doi:10.1016/0005-2728(95)00096-2.
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[8]
1994 | Published | Journal Article | IST-REx-ID: 1949 | OA
Sazanov, Leonid A., and Julie Jackson. “Proton Translocating Transhydrogenase and NAD- and NADP-Linked Isocitrate Dehydrogenases Operate in a Substrate Cycle Which Contributes to Fine Regulation of the Tricarboxylic Acid Cycle Activity in Mitochondria.” FEBS Letters, vol. 344, no. 2–3, Elsevier, 1994, pp. 109–16, doi:10.1016/0014-5793(94)00370-X.
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[7]
1994 | Published | Journal Article | IST-REx-ID: 1953 | OA
Efanov, Alexander, et al. “Inhibition of the Respiratory Burst in Mouse Macrophages by Ultra-Low Doses of an Opioid Peptide Is Consistent with a Possible Adaptation Mechanism.” FEBS Letters, vol. 355, no. 2, Elsevier, 1994, pp. 114–16, doi:10.1016/0014-5793(94)01109-5.
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[6]
1993 | Published | Journal Article | IST-REx-ID: 1947
Sazanov, Leonid A., and Julie Jackson. “Activation and Inhibition of Mitochondrial Transhydrogenase by Metal Ions.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1144, no. 2, Elsevier, 1993, pp. 225–28, doi:10.1016/0005-2728(93)90177-H.
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[5]
1993 | Published | Journal Article | IST-REx-ID: 1948
Sazanov, Leonid A., and Julie Jackson. “Possible Functions of the NADP-Linked Isocitrate Dehydrogenase and H+ -Transhydrogenase in Heart Mitochondria .” Biochemical Society Transactions, vol. 21, no. 3, Portland Press, 1993, p. 260, doi:10.1042/bst021260s.
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[4]
1993 | Published | Journal Article | IST-REx-ID: 1950
Jackson, Julie, et al. “Proton-Translocating Transhydrogenase in Bacteria.” Biochemical Society Transactions, vol. 21, no. 4, Portland Press, 1993, pp. 1010–13, doi:10.1042/bst0211010.
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[3]
1992 | Published | Journal Article | IST-REx-ID: 1945
Sazanov, Leonid A., and Sergei Zaǐtsev. “Effect of Superlow Doses (10(-18)-10-(-14) M) of Biologically Active Substances: General Rules, Features, and Possible Mechanisms.” Biochemistry (Moscow), vol. 57, no. 10, Izdatel’stvo Nauka, 1992, pp. 1443–60.
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[2]
1991 | Published | Journal Article | IST-REx-ID: 1946
Zaǐtsev, Sergei, et al. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters, vol. 291, no. 1, Elsevier, 1991, pp. 84–86, doi:10.1016/0014-5793(91)81109-L.
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[1]
1988 | Published | Journal Article | IST-REx-ID: 1941
Sazanov, Leonid A., et al. “Mathematical model of photosynthesis regulation accounts for the effects of changes in external conditions and observed oscillations.” Russian Journal of Physical Chemistry B, vol. 52, Elsevier, 1988, pp. 3351–54.
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[75]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 18987 | OA
Kaiyrzhanov R, Thompson K, Efthymiou S, Mukushev A, Zharylkassyn A, Prasad C, Karimiani EG, Alvi JR, Niyazov D, Alahmad A, Babaei M, Tajsharghi H, Albash B, Alaqeel A, Charif M, Hashemi N, Heidari M, Kalantar SM, Lenaers G, Mehrjardi MYV, Srinivasan VM, Gowda VK, Mirabutalebi SH, Carere DA, Movahedinia M, Murphy D, Mcfarland R, Abdel-Hamid MS, Elhossini RM, Alavi S, Napier M, Belanger-Quintana A, Prasad AN, Jakobczyk J, Roubertie A, Rupar T, Sultan T, Toosi MB, Sazanov LA, Severino M, Houlden H, Taylor RW, Maroofian R. 2025. Biallelic NDUFA13 variants lead to a neurodevelopmental phenotype with gradual neurological impairment. Brain Communications. 7(1), fcae453.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[74]
2024 | Published | Other Publication | IST-REx-ID: 18967 | OA
Petrova, Olga, et al. “Structure‐activity Relationship Study of Neuroprotective Complex I Inhibitor CP2.” Alzheimer’s & Dementia, vol. 20, no. S6, e085971, Wiley, 2024, doi:10.1002/alz.085971.
[Published Version] View | Files available | DOI
 
[73]
2024 | Published | Journal Article | IST-REx-ID: 15323 | OA
Vercellino, Irene, and Leonid A. Sazanov. “SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes.” Nature Structural and Molecular Biology, vol. 31, Springer Nature, 2024, pp. 1061–71, doi:10.1038/s41594-024-01255-0.
[Submitted Version] View | Files available | DOI | PubMed | Europe PMC
 
[72]
2023 | Published | Journal Article | IST-REx-ID: 12757 | OA
Sazanov, Leonid A. “From the ‘black Box’ to ‘Domino Effect’ Mechanism: What Have We Learned from the Structures of Respiratory Complex I.” The Biochemical Journal, vol. 480, no. 5, Portland Press, 2023, pp. 319–33, doi:10.1042/BCJ20210285.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[71]
2023 | Published | Journal Article | IST-REx-ID: 14040 | OA
Zhao, Ziyu, et al. “The Ycf48 Accessory Factor Occupies the Site of the Oxygen-Evolving Manganese Cluster during Photosystem II Biogenesis.” Nature Communications, vol. 14, 4681, Springer Nature, 2023, doi:10.1038/s41467-023-40388-6.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[70]
2022 | Published | Journal Article | IST-REx-ID: 11167 | OA
Kampjut, Domen, and Leonid A. Sazanov. “Structure of Respiratory Complex I – An Emerging Blueprint for the Mechanism.” Current Opinion in Structural Biology, vol. 74, 102350, Elsevier, 2022, doi:10.1016/j.sbi.2022.102350.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[69]
2022 | Published | Journal Article | IST-REx-ID: 11551 | OA
Molina-Granada, David, et al. “Most Mitochondrial DGTP Is Tightly Bound to Respiratory Complex I through the NDUFA10 Subunit.” Communications Biology, vol. 5, no. 1, 620, Springer Nature, 2022, doi:10.1038/s42003-022-03568-6.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[68]
2022 | Published | Journal Article | IST-REx-ID: 10182
Vercellino, Irene, and Leonid A. Sazanov. “The Assembly, Regulation and Function of the Mitochondrial Respiratory Chain.” Nature Reviews Molecular Cell Biology, vol. 23, Springer Nature, 2022, pp. 141–161, doi:10.1038/s41580-021-00415-0.
View | DOI | WoS | PubMed | Europe PMC
 
[67]
2022 | Published | Journal Article | IST-REx-ID: 12138 | OA
Kravchuk, Vladyslav, et al. “A Universal Coupling Mechanism of Respiratory Complex I.” Nature, vol. 609, no. 7928, Springer Nature, 2022, pp. 808–14, doi:10.1038/s41586-022-05199-7.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[66]
2021 | Published | Journal Article | IST-REx-ID: 9205 | OA
Kampjut, Domen, et al. “Cryo-EM Grid Optimization for Membrane Proteins.” IScience, vol. 24, no. 3, 102139, Elsevier, 2021, doi:10.1016/j.isci.2021.102139.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[65]
2021 | Published | Journal Article | IST-REx-ID: 10146
Vercellino, Irene, and Leonid A. Sazanov. “Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV.” Nature, vol. 598, no. 7880, Springer Nature, 2021, pp. 364–67, doi:10.1038/s41586-021-03927-z.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[64]
2021 | Published | Journal Article | IST-REx-ID: 8993 | OA
Abas, Lindy, Naphthylphthalamic acid associates with and inhibits PIN auxin transporters. Proceedings of the National Academy of Sciences of the United States of America 118 (1). 2021
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[63]
2020 | Published | Journal Article | IST-REx-ID: 8318 | OA
Gutierrez-Fernandez, Javier, et al. “Key Role of Quinone in the Mechanism of Respiratory Complex I.” Nature Communications, vol. 11, no. 1, 4135, Springer Nature, 2020, doi:10.1038/s41467-020-17957-0.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[62]
2020 | Published | Journal Article | IST-REx-ID: 8040
Gupta, Chitrak, Charge transfer and chemo-mechanical coupling in respiratory complex I. Journal of the American Chemical Society 142 (20). 2020
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[61]
2020 | Research Data Reference | IST-REx-ID: 9326
Gupta, Chitrak, et al. Charge Transfer and Chemo-Mechanical Coupling in Respiratory Complex I. American Chemical Society, 2020, doi:10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[60]
2020 | Research Data Reference | IST-REx-ID: 9713
Gupta, Chitrak, et al. Supporting Information. American Chemical Society , 2020, doi:10.1021/jacs.9b13450.s001.
[Published Version] View | Files available | DOI
 
[59]
2020 | Research Data Reference | IST-REx-ID: 9878
Gupta, Chitrak, et al. Movies. American Chemical Society, 2020, doi:10.1021/jacs.9b13450.s002.
[Published Version] View | Files available | DOI
 
[58]
2020 | Published | Journal Article | IST-REx-ID: 7788 | OA
Adjobo-Hermans, Merel J.W., NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. Biochimica et Biophysica Acta - Bioenergetics 1861 (8). 2020
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[57]
2020 | Published | Journal Article | IST-REx-ID: 8581
Pinke, Gergely, Cryo-EM structure of the entire mammalian F-type ATP synthase. Nature Structural and Molecular Biology 27 (11). 2020
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[56]
2020 | Published | Journal Article | IST-REx-ID: 8737 | OA
Kampjut, Domen, and Leonid A. Sazanov. “The Coupling Mechanism of Mammalian Respiratory Complex I.” Science, vol. 370, no. 6516, eabc4209, American Association for the Advancement of Science, 2020, doi:10.1126/science.abc4209.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[55]
2020 | Published | Journal Article | IST-REx-ID: 8284 | OA
Steiner, Julia, and Leonid A. Sazanov. “Structure and Mechanism of the Mrp Complex, an Ancient Cation/Proton Antiporter.” ELife, vol. 9, e59407, eLife Sciences Publications, 2020, doi:10.7554/eLife.59407.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[54]
2019 | Published | Journal Article | IST-REx-ID: 6859
Zhou, Long, and Leonid A. Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science, vol. 365, no. 6455, eaaw9144, AAAS, 2019, doi:10.1126/science.aaw9144.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[53]
2019 | Published | Journal Article | IST-REx-ID: 7395 | OA
Letts, James A., et al. “Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk.” Molecular Cell, vol. 75, no. 6, Cell Press, 2019, p. 1131–1146.e6, doi:10.1016/j.molcel.2019.07.022.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[52]
2019 | Published | Journal Article | IST-REx-ID: 6848 | OA
Kampjut, Domen, and Leonid A. Sazanov. “Structure and Mechanism of Mitochondrial Proton-Translocating Transhydrogenase.” Nature, vol. 573, no. 7773, Springer Nature, 2019, pp. 291–295, doi:10.1038/s41586-019-1519-2.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[51]
2018 | Published | Journal Article | IST-REx-ID: 152 | OA
Fiedorczuk, Karol, and Leonid A. Sazanov. “Mammalian Mitochondrial Complex I Structure and Disease Causing Mutations.” Trends in Cell Biology, vol. 28, no. 10, Elsevier, 2018, pp. 835–67, doi:10.1016/j.tcb.2018.06.006.
[Submitted Version] View | Files available | DOI | WoS
 
[50]
2017 | Published | Journal Article | IST-REx-ID: 443 | OA
Hardie, Rae, et al. “Mitochondrial Mutations and Metabolic Adaptation in Pancreatic Cancer.” Cancer & Metabolism, vol. 5, no. 2, BioMed Central, 2017, doi:10.1186/s40170-017-0164-1.
[Published Version] View | Files available | DOI
 
[49]
2017 | Published | Book Chapter | IST-REx-ID: 444
Sazanov, Leonid A. “Structure of Respiratory Complex I: ‘Minimal’ Bacterial and ‘de Luxe’ Mammalian Versions.” Mechanisms of Primary Energy Transduction in Biology , edited by Mårten Wikström, Royal Society of Chemistry, 2017, pp. 25–59, doi:10.1039/9781788010405-00025.
View | DOI
 
[48]
2017 | Published | Journal Article | IST-REx-ID: 515 | OA
Letts, James A, Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain. Nature Structural and Molecular Biology 24 (10). 2017
[Submitted Version] View | Files available | DOI
 
[47]
2016 | Published | Journal Article | IST-REx-ID: 1288
Holt, Peter, et al. “Reversible FMN Dissociation from Escherichia Coli Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1857, no. 11, Elsevier, 2016, pp. 1777–85, doi:10.1016/j.bbabio.2016.08.008.
View | DOI
 
[46]
2016 | Published | Journal Article | IST-REx-ID: 1521
Berrisford, John, et al. “Structure of Bacterial Respiratory Complex I.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1857, no. 7, Elsevier, 2016, pp. 892–901, doi:10.1016/j.bbabio.2016.01.012.
View | DOI
 
[45]
2016 | Published | Journal Article | IST-REx-ID: 1209 | OA
Letts, James A., et al. “Purification of Ovine Respiratory Complex i Results in a Highly Active and Stable Preparation.” Journal of Biological Chemistry, vol. 291, no. 47, American Society for Biochemistry and Molecular Biology, 2016, pp. 24657–75, doi:10.1074/jbc.M116.735142.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
[44]
2016 | Published | Journal Article | IST-REx-ID: 1226 | OA
Fiedorczuk, Karol, et al. “Atomic Structure of the Entire Mammalian Mitochondrial Complex I.” Nature, vol. 538, no. 7625, Nature Publishing Group, 2016, pp. 406–10, doi:10.1038/nature19794.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[43]
2016 | Published | Journal Article | IST-REx-ID: 1232
Letts, James A., et al. “The Architecture of Respiratory Supercomplexes.” Nature, vol. 537, no. 7622, Nature Publishing Group, 2016, pp. 644–48, doi:10.1038/nature19774.
View | DOI
 
[42]
2015 | Published | Journal Article | IST-REx-ID: 1683
Letts, James A., and Leonid A. Sazanov. “Gaining Mass: The Structure of Respiratory Complex I-from Bacterial towards Mitochondrial Versions.” Current Opinion in Structural Biology, vol. 33, no. 8, Elsevier, 2015, pp. 135–45, doi:10.1016/j.sbi.2015.08.008.
View | DOI
 
[41]
2015 | Published | Journal Article | IST-REx-ID: 1638
Sazanov, Leonid A. “A Giant Molecular Proton Pump: Structure and Mechanism of Respiratory Complex I.” Nature Reviews Molecular Cell Biology, vol. 16, no. 6, Nature Publishing Group, 2015, pp. 375–88, doi:10.1038/nrm3997.
View | DOI
 
[40]
2014 | Published | Journal Article | IST-REx-ID: 1979
Sazanov, Leonid A. “The Mechanism of Coupling between Electron Transfer and Proton Translocation in Respiratory Complex I.” Journal of Bioenergetics and Biomembranes, vol. 46, no. 4, Springer, 2014, pp. 247–53, doi:10.1007/s10863-014-9554-z.
View | DOI
 
[39]
2014 | Published | Journal Article | IST-REx-ID: 1980
Heikal, Adam, et al. “Structure of the Bacterial Type II NADH Dehydrogenase: A Monotopic Membrane Protein with an Essential Role in Energy Generation.” Molecular Microbiology, vol. 91, no. 5, Wiley-Blackwell, 2014, pp. 950–64, doi:10.1111/mmi.12507.
View | DOI
 
[38]
2014 | Published | Book Review | IST-REx-ID: 1981
Garvin, Michael, et al. “Review and Meta-Analysis of Natural Selection in Mitochondrial Complex I in Metazoans.” Journal of Zoological Systematics and Evolutionary Research, vol. 53, no. 1, Wiley-Blackwell, 2014, pp. 1–17, doi:10.1111/jzs.12079.
View | DOI
 
[37]
2013 | Published | Journal Article | IST-REx-ID: 1977
Sazanov, Leonid A., et al. “A Long Road towards the Structure of Respiratory Complex I, a Giant Molecular Proton Pump.” Biochemical Society Transactions, vol. 41, no. 5, Portland Press, 2013, pp. 1265–71, doi:10.1042/BST20130193.
View | DOI
 
[36]
2013 | Published | Journal Article | IST-REx-ID: 1978
Baradaran, Rozbeh, et al. “Crystal Structure of the Entire Respiratory Complex I.” Nature, vol. 494, no. 7438, Nature Publishing Group, 2013, pp. 443–48, doi:10.1038/nature11871.
View | DOI
 
[35]
2012 | Published | Journal Article | IST-REx-ID: 1972
Efremov, Rouslan, and Leonid A. Sazanov. “Structure of Escherichia Coli OmpF Porin from Lipidic Mesophase.” Journal of Structural Biology, vol. 178, no. 3, Academic Press, 2012, pp. 311–18, doi:10.1016/j.jsb.2012.03.005.
View | DOI
 
[34]
2012 | Published | Book Review | IST-REx-ID: 1976
Efremov, Rouslan, and Leonid A. Sazanov. “The Coupling Mechanism of Respiratory Complex i - A Structural and Evolutionary Perspective.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1817, no. 10, Elsevier, 2012, pp. 1785–95, doi:10.1016/j.bbabio.2012.02.015.
View | DOI
 
[33]
2011 | Published | Journal Article | IST-REx-ID: 1973
Efremov, Rouslan, and Leonid A. Sazanov. “Structure of the Membrane Domain of Respiratory Complex I.” Nature, vol. 476, no. 7361, Nature Publishing Group, 2011, pp. 414–21, doi:10.1038/nature10330.
View | DOI
 
[32]
2011 | Published | Journal Article | IST-REx-ID: 1974
Efremov, Rouslan, and Leonid A. Sazanov. “Respiratory Complex I: ‘steam Engine’ of the Cell?” Current Opinion in Structural Biology, vol. 21, no. 4, Elsevier, 2011, pp. 532–40, doi:10.1016/j.sbi.2011.07.002.
View | DOI
 
[31]
2011 | Published | Journal Article | IST-REx-ID: 1975
Yip, Chui, et al. “Evolution of Respiratory Complex I "Supernumerary" Subunits Are Present in the α-Proteobacterial Enzyme.” Journal of Biological Chemistry, vol. 286, no. 7, American Society for Biochemistry and Molecular Biology, 2011, pp. 5023–33, doi:10.1074/jbc.M110.194993.
View | DOI
 
[30]
2010 | Published | Journal Article | IST-REx-ID: 1970
Efremov, Rouslan, et al. “The Architecture of Respiratory Complex I.” Nature, vol. 465, no. 7297, Nature Publishing Group, 2010, pp. 441–45, doi:10.1038/nature09066.
View | DOI
 
[29]
2009 | Published | Journal Article | IST-REx-ID: 1971
Berrisford, John, and Leonid A. Sazanov. “Structural Basis for the Mechanism of Respiratory Complex I.” Journal of Biological Chemistry, vol. 284, no. 43, American Society for Biochemistry and Molecular Biology, 2009, pp. 29773–83, doi:10.1074/jbc.M109.032144.
View | DOI
 
[28]
2008 | Published | Journal Article | IST-REx-ID: 1967
Berrisford, John, et al. “Chemical and NADH-Induced, ROS-Dependent, Cross-Linking between Sublimits of Complex I from Escherichia Coli and Thermus Thermophilus.” Biochemistry, vol. 47, no. 39, ACS, 2008, pp. 10262–70, doi:10.1021/bi801160u.
View | DOI
 
[27]
2008 | Published | Journal Article | IST-REx-ID: 1968
Morgan, David, and Leonid A. Sazanov. “Three-Dimensional Structure of Respiratory Complex I from Escherichia Coli in Ice in the Presence of Nucleotides.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1777, no. 7–8, Elsevier, 2008, pp. 711–18, doi:10.1016/j.bbabio.2008.03.023.
View | DOI
 
[26]
2007 | Published | Journal Article | IST-REx-ID: 1964
Sazanov, Leonid A. “Respiratory Complex I: Mechanistic and Structural Insights Provided by the Crystal Structure of the Hydrophilic Domain.” Biochemistry, vol. 46, no. 9, ACS, 2007, pp. 2275–88, doi:10.1021/bi602508x.
View | DOI
 
[25]
2007 | Published | Journal Article | IST-REx-ID: 1965
Baranova, Ekaterina, et al. “Projection Structure of the Membrane Domain of Escherichia Coli Respiratory Complex I at 8 Å Resolution.” Journal of Molecular Biology, vol. 366, no. 1, Elsevier, 2007, pp. 140–54, doi:10.1016/j.jmb.2006.11.026.
View | DOI
 
[24]
2007 | Published | Journal Article | IST-REx-ID: 1969
Baranova, Ekaterina, et al. “Single Particle Analysis Confirms Distal Location of Subunits NuoL and NuoM in Escherichia Coli Complex I.” Journal of Structural Biology, vol. 159, no. 2 SPEC. ISS., Academic Press, 2007, pp. 238–42, doi:10.1016/j.jsb.2007.01.009.
View | DOI
 
[23]
2006 | Published | Journal Article | IST-REx-ID: 1961
Sazanov, Leonid A., and Philip Hinchliffe. “Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus Thermophilus.” Science, vol. 311, no. 5766, American Association for the Advancement of Science, 2006, pp. 1430–36, doi:10.1126/science.1123809.
View | DOI
 
[22]
2006 | Published | Journal Article | IST-REx-ID: 1966
Hinchliffe, Philip, et al. “Identification of a Novel Subunit of Respiratory Complex I from Thermus Thermophilus.” Biochemistry, vol. 45, no. 14, ACS, 2006, pp. 4413–20, doi:10.1021/bi0600998.
View | DOI
 
[21]
2005 | Published | Journal Article | IST-REx-ID: 1962
Hinchliffe, Philip, and Leonid A. Sazanov. “Biochemistry: Organization of Iron-Sulfur Clusters in Respiratory Complex I.” Science, vol. 309, no. 5735, American Association for the Advancement of Science, 2005, pp. 771–74, doi:10.1126/science.1113988.
View | DOI
 
[20]
2004 | Published | Journal Article | IST-REx-ID: 1963
Mamedova, Aygun, et al. “Substrate-Induced Conformational Change in Bacterial Complex I.” Journal of Biological Chemistry, vol. 279, no. 22, American Society for Biochemistry and Molecular Biology, 2004, pp. 23830–36, doi:10.1074/jbc.M401539200.
View | DOI
 
[19]
2003 | Published | Journal Article | IST-REx-ID: 1959
Holt, Peter, et al. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry, vol. 278, no. 44, American Society for Biochemistry and Molecular Biology, 2003, pp. 43114–20, doi:10.1074/jbc.M308247200.
View | DOI
 
[18]
2003 | Published | Journal Article | IST-REx-ID: 1960
Sazanov, Leonid A., et al. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry, vol. 278, no. 21, American Society for Biochemistry and Molecular Biology, 2003, pp. 19483–91, doi:10.1074/jbc.M208959200.
View | DOI
 
[17]
2000 | Published | Journal Article | IST-REx-ID: 1957
Sazanov, Leonid A., and John Walker. “Cryo-Electron Crystallography of Two Sub-Complexes of Bovine Complex I Reveals the Relationship between the Membrane and Peripheral Arms.” Journal of Molecular Biology, vol. 302, no. 2, Elsevier, 2000, pp. 455–64, doi:10.1006/jmbi.2000.4079.
View | DOI | PubMed | Europe PMC
 
[16]
2000 | Published | Journal Article | IST-REx-ID: 1958
Sazanov, Leonid A., et al. “Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme.” Biochemistry, vol. 39, no. 24, ACS, 2000, pp. 7229–35, doi:10.1021/bi000335t.
View | DOI | PubMed | Europe PMC
 
[15]
1998 | Published | Journal Article | IST-REx-ID: 1954
Sazanov, Leonid A., et al. “The Chloroplast Ndh Complex Mediates the Dark Reduction of the Plastoquinone Pool in Response to Heat Stress in Tobacco Leaves.” FEBS Letters, vol. 429, no. 1, Elsevier, 1998, pp. 115–18, doi:10.1016/S0014-5793(98)00573-0.
View | DOI | PubMed | Europe PMC
 
[14]
1998 | Published | Journal Article | IST-REx-ID: 1955 | OA
Burrows, Paul, et al. “Identification of a Functional Respiratory Complex in Chloroplasts through Analysis of Tobacco Mutants Containing Disrupted Plastid Ndh Genes.” EMBO Journal, vol. 17, no. 4, Wiley-Blackwell, 1998, pp. 868–76, doi:10.1093/emboj/17.4.868.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[13]
1998 | Published | Journal Article | IST-REx-ID: 1956 | OA
Sazanov, Leonid A., et al. “The Plastid Ndh Genes Code for an NADH-Specific Dehydrogenase: Isolation of a Complex I Analogue from Pea Thylakoid Membranes.” PNAS, vol. 95, no. 3, National Academy of Sciences, 1998, pp. 1319–24, doi:10.1073/pnas.95.3.1319.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[12]
1996 | Published | Conference Paper | IST-REx-ID: 1942
Sazanov, Leonid A., et al. Presence of a Large Protein Complex Containing the NdhK Gene Product and Possessing NADH-Specific Dehydrogenase Activity in Thylakoid Membranes of Higher Plant Chloroplasts. Vol. 2, Kluwer, 1996, pp. 705–08.
View
 
[11]
1996 | Published | Journal Article | IST-REx-ID: 1951
Sazanov, Leonid A., et al. “Detection and Characterization of a Complex I-like NADH-Specific Dehydrogenase from Pea Thylakoids.” Biochemical Society Transactions, vol. 24, no. 3, Portland Press, 1996, pp. 739–43, doi:10.1042/bst0240739.
View | DOI | PubMed | Europe PMC
 
[10]
1996 | Published | Journal Article | IST-REx-ID: 1952
Bizouarn, Tania, et al. “Estimation of the H+/H- Ratio of the Reaction Catalysed by the Nicotinamide Nucleotide Transhydrogenase in Chromatophores from over-Expressing Strains of Rhodospirillum Rubrum and in Liposomes Inlaid with the Purified Bovine Enzyme.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1273, no. 1, Elsevier, 1996, pp. 4–12, doi:10.1016/0005-2728(95)00125-5.
View | DOI | PubMed | Europe PMC
 
[9]
1995 | Published | Journal Article | IST-REx-ID: 1943 | OA
Sazanov, Leonid A., and Baz Jackson. “Cyclic Reactions Catalysed by Detergent-Dispersed and Reconstituted Transhydrogenase from Beef Heart Mitochondria; Implications for the Mechanism of Proton Translocation.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1231, no. 3, Elsevier, 1995, pp. 304–12, doi:10.1016/0005-2728(95)00096-2.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[8]
1994 | Published | Journal Article | IST-REx-ID: 1949 | OA
Sazanov, Leonid A., and Julie Jackson. “Proton Translocating Transhydrogenase and NAD- and NADP-Linked Isocitrate Dehydrogenases Operate in a Substrate Cycle Which Contributes to Fine Regulation of the Tricarboxylic Acid Cycle Activity in Mitochondria.” FEBS Letters, vol. 344, no. 2–3, Elsevier, 1994, pp. 109–16, doi:10.1016/0014-5793(94)00370-X.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[7]
1994 | Published | Journal Article | IST-REx-ID: 1953 | OA
Efanov, Alexander, et al. “Inhibition of the Respiratory Burst in Mouse Macrophages by Ultra-Low Doses of an Opioid Peptide Is Consistent with a Possible Adaptation Mechanism.” FEBS Letters, vol. 355, no. 2, Elsevier, 1994, pp. 114–16, doi:10.1016/0014-5793(94)01109-5.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[6]
1993 | Published | Journal Article | IST-REx-ID: 1947
Sazanov, Leonid A., and Julie Jackson. “Activation and Inhibition of Mitochondrial Transhydrogenase by Metal Ions.” Biochimica et Biophysica Acta - Bioenergetics, vol. 1144, no. 2, Elsevier, 1993, pp. 225–28, doi:10.1016/0005-2728(93)90177-H.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[5]
1993 | Published | Journal Article | IST-REx-ID: 1948
Sazanov, Leonid A., and Julie Jackson. “Possible Functions of the NADP-Linked Isocitrate Dehydrogenase and H+ -Transhydrogenase in Heart Mitochondria .” Biochemical Society Transactions, vol. 21, no. 3, Portland Press, 1993, p. 260, doi:10.1042/bst021260s.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[4]
1993 | Published | Journal Article | IST-REx-ID: 1950
Jackson, Julie, et al. “Proton-Translocating Transhydrogenase in Bacteria.” Biochemical Society Transactions, vol. 21, no. 4, Portland Press, 1993, pp. 1010–13, doi:10.1042/bst0211010.
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[3]
1992 | Published | Journal Article | IST-REx-ID: 1945
Sazanov, Leonid A., and Sergei Zaǐtsev. “Effect of Superlow Doses (10(-18)-10-(-14) M) of Biologically Active Substances: General Rules, Features, and Possible Mechanisms.” Biochemistry (Moscow), vol. 57, no. 10, Izdatel’stvo Nauka, 1992, pp. 1443–60.
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[2]
1991 | Published | Journal Article | IST-REx-ID: 1946
Zaǐtsev, Sergei, et al. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters, vol. 291, no. 1, Elsevier, 1991, pp. 84–86, doi:10.1016/0014-5793(91)81109-L.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[1]
1988 | Published | Journal Article | IST-REx-ID: 1941
Sazanov, Leonid A., et al. “Mathematical model of photosynthesis regulation accounts for the effects of changes in external conditions and observed oscillations.” Russian Journal of Physical Chemistry B, vol. 52, Elsevier, 1988, pp. 3351–54.
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