Michael K Sixt

131 Publications

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[131]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 19928 | OA
Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis
Gawish R, Varada R, Deckert F, Hladik A, Steinbichl L, Cimatti L, Milanovic K, Jain M, Torgasheva N, Tanzer A, De Paepe K, Van De Wiele T, Hausmann B, Lang M, Pechhacker M, Ibrahim N, de Vries I, Brostjan C, Sixt MK, Gasche C, Boon L, Berry D, Jantsch MF, Pereira FC, Vesely C. 2025. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. 222(9), e20240109.
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[130]
2025 | Published | Journal Article | IST-REx-ID: 20082 | OA | PlanS
Migrating immune cells globally coordinate protrusive forces
P. Dos Reis Rodrigues, M. Avellaneda Sarrió, N. Canigova, F.R. Gärtner, K. Vaahtomeri, M. Riedl, I. de Vries, J. Merrin, R. Hauschild, Y. Fukui, A. Juanes Garcia, M.K. Sixt, Nature Immunology 26 (2025) 1258–1266.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[129]
2024 | Published | Journal Article | IST-REx-ID: 17279
Rescuing T cells from stiff tumors
M. Avellaneda Sarrió, M.K. Sixt, Cell Chemical Biology 31 (2024) 1242–1243.
View | DOI | PubMed | Europe PMC
 
[128]
2024 | Published | Journal Article | IST-REx-ID: 17284 | OA
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis
Gärtner FR, Ishikawa-Ankerhold H, Stutte S, Fu W, Weitz J, Dueck A, Nelakuditi B, Fumagalli V, Van Den Heuvel D, Belz L, Sobirova G, Zhang Z, Titova A, Navarro AM, Pekayvaz K, Lorenz M, Von Baumgarten L, Kranich J, Straub T, Popper B, Zheden V, Kaufmann W, Guo C, Piontek G, Von Stillfried S, Boor P, Colonna M, Clauß S, Schulz C, Brocker T, Walzog B, Scheiermann C, Aird WC, Nerlov C, Stark K, Petzold T, Engelhardt S, Sixt MK, Hauschild R, Rudelius M, Oostendorp RAJ, Iannacone M, Heinig M, Massberg S. 2024. Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis. Nature. 631, 645–653.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[127]
2024 | Published | Journal Article | IST-REx-ID: 15146 | OA
Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix
B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[126]
2024 | Published | Journal Article | IST-REx-ID: 15408 | OA
Integrin β1–mediated mast cell immune-surveillance of blood vessel content
K. Link, L. Muhandes, A. Polikarpova, T. Lämmermann, M.K. Sixt, R. Fässler, A. Roers, Journal of Allergy and Clinical Immunology 154 (2024) 745–753.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[125]
2024 | Published | Journal Article | IST-REx-ID: 17191
Nuclear squeezing wakes up dendritic cells
S. Lembo, M.K. Sixt, Nature Immunology 25 (2024) 1131–1132.
View | DOI | PubMed | Europe PMC
 
[124]
2023 | Published | Book Chapter | IST-REx-ID: 13052
En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses
A.F. Leithner, J. Merrin, M.K. Sixt, in:, C. Baldari, M. Dustin (Eds.), The Immune Synapse, Springer Nature, New York, NY, 2023, pp. 137–147.
View | DOI | PubMed | Europe PMC
 
[123]
2023 | Published | Journal Article | IST-REx-ID: 14361 | OA
Synchronization in collectively moving inanimate and living active matter
M. Riedl, I.D. Mayer, J. Merrin, M.K. Sixt, B. Hof, Nature Communications 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[122]
2023 | Published | Journal Article | IST-REx-ID: 14555 | OA
The excitable nature of polymerizing actin and the Belousov-Zhabotinsky reaction
M. Riedl, M.K. Sixt, Frontiers in Cell and Developmental Biology 11 (2023).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[121]
2023 | Published | Journal Article | IST-REx-ID: 14274 | OA
CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
J.H. Alanko, M.C. Ucar, N. Canigova, J.A. Stopp, J. Schwarz, J. Merrin, E.B. Hannezo, M.K. Sixt, Science Immunology 8 (2023).
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[120]
2023 | Published | Journal Article | IST-REx-ID: 14360 | OA
Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
E. Sitarska, S.D. Almeida, M.S. Beckwith, J.A. Stopp, J. Czuchnowski, M. Siggel, R. Roessner, A. Tschanz, C. Ejsing, Y. Schwab, J. Kosinski, M.K. Sixt, A. Kreshuk, A. Erzberger, A. Diz-Muñoz, Nature Communications 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[119]
2022 | Published | Journal Article | IST-REx-ID: 12133
Principles of disease defence in organisms, superorganisms and societies
S. Cremer, M.K. Sixt, Nature Reviews Immunology 22 (2022) 713–714.
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[118]
2022 | Published | Journal Article | IST-REx-ID: 11843 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[117]
2022 | Published | Journal Article | IST-REx-ID: 9794 | OA
Multitier mechanics control stromal adaptations in swelling lymph nodes
F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg, W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology 23 (2022) 1246–1255.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[116]
2022 | Published | Journal Article | IST-REx-ID: 12272 | OA
Plan your trip before you leave: The neutrophils’ search-and-run journey
J.A. Stopp, M.K. Sixt, Journal of Cell Biology 221 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[115]
2022 | Published | Journal Article | IST-REx-ID: 10703 | OA
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
F. Gaertner, P. Dos Reis Rodrigues, I. de Vries, M. Hons, J. Aguilera, M. Riedl, A.F. Leithner, S. Tasciyan, A. Kopf, J. Merrin, V. Zheden, W. Kaufmann, R. Hauschild, M.K. Sixt, Developmental Cell 57 (2022) 47–62.e9.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[114]
2021 | Published | Journal Article | IST-REx-ID: 10834 | OA
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | PubMed | Europe PMC
 
[113]
2021 | Published | Journal Article | IST-REx-ID: 9094 | OA
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[112]
2021 | Published | Journal Article | IST-REx-ID: 9259 | OA
Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[111]
2021 | Published | Journal Article | IST-REx-ID: 9294 | OA
Engaging the front wheels to drive through fibrous terrain
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[110]
2021 | Published | Journal Article | IST-REx-ID: 9822 | OA
Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[109]
2021 | Draft | Preprint | IST-REx-ID: 10316 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
[108]
2020 | Published | Journal Article | IST-REx-ID: 7234 | OA
Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes
P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson, M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020) 93–113.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[107]
2020 | Published | Journal Article | IST-REx-ID: 7909 | OA
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[106]
2020 | Published | Journal Article | IST-REx-ID: 8142 | OA
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
J.C. Montesinos López, A. Abuzeineh, A. Kopf, A. Juanes Garcia, K. Ötvös, J. Petrášek, M.K. Sixt, E. Benková, The Embo Journal 39 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[105]
2020 | Published | Journal Article | IST-REx-ID: 7875 | OA
Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[104]
2020 | Published | Journal Article | IST-REx-ID: 8132 | OA
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt MK, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. 2020. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology. 5(49), eabc3979.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[103]
2020 | Published | Journal Article | IST-REx-ID: 7623 | OA
Modeling adhesion-independent cell migration
G. Jankowiak, D. Peurichard, A. Reversat, C. Schmeiser, M.K. Sixt, Mathematical Models and Methods in Applied Sciences 30 (2020) 513–537.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | arXiv
 
[102]
2020 | Published | Journal Article | IST-REx-ID: 7876 | OA
T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[101]
2020 | Published | Journal Article | IST-REx-ID: 7885 | OA
Cellular locomotion using environmental topography
A. Reversat, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
[Preprint] View | Files available | DOI | Download Preprint (ext.) | WoS | PubMed | Europe PMC
 
[100]
2020 | Published | Journal Article | IST-REx-ID: 8190 | OA
Zena Werb (1945-2020): Cell biology in context
M.K. Sixt, A. Huttenlocher, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[99]
2019 | Published | Journal Article | IST-REx-ID: 6979
Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal
A. Kopf, M.K. Sixt, Current Biology 29 (2019) R1091–R1093.
View | DOI | WoS | PubMed | Europe PMC
 
[98]
2019 | Published | Journal Article | IST-REx-ID: 7009
Mechanisms of 3D cell migration
K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
View | DOI | WoS | PubMed | Europe PMC
 
[97]
2019 | Published | Journal Article | IST-REx-ID: 7105 | OA
Persistent and polarized global actin flow is essential for directionality during cell migration
L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E. Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G. Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[96]
2019 | Published | Journal Article | IST-REx-ID: 6328 | OA
Nuclear positioning facilitates amoeboid migration along the path of least resistance
J. Renkawitz, A. Kopf, J.A. Stopp, I. de Vries, M.K. Driscoll, J. Merrin, R. Hauschild, E.S. Welf, G. Danuser, R. Fiolka, M.K. Sixt, Nature 568 (2019) 546–550.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[95]
2019 | Published | Journal Article | IST-REx-ID: 6877
The neural crest pitches in to remove apoptotic debris
A. Kopf, M.K. Sixt, Cell 179 (2019) 51–53.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[94]
2018 | Published | Journal Article | IST-REx-ID: 5672 | OA
IgM's exit route
A. Reversat, M.K. Sixt, Journal of Experimental Medicine 215 (2018) 2959–2961.
[Published Version] View | Files available | DOI | WoS
 
[93]
2018 | Published | Journal Article | IST-REx-ID: 5992 | OA
On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility
S. Dolati, F. Kage, J. Mueller, M. Müsken, M. Kirchner, G. Dittmar, M.K. Sixt, K. Rottner, M. Falcke, Molecular Biology of the Cell 29 (2018) 2674–2686.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[92]
2018 | Published | Journal Article | IST-REx-ID: 6497 | OA
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+T cells
F. Moalli, X. Ficht, P. Germann, M. Vladymyrov, B. Stolp, I. de Vries, R. Lyck, J. Balmer, A. Fiocchi, M. Kreutzfeldt, D. Merkler, M. Iannacone, A. Ariga, M.H. Stoffel, J. Sharpe, M. Bähler, M.K. Sixt, A. Diz-Muñoz, J.V. Stein, The Journal of Experimental Medicine 2015 (2018) 1869–1890.
[Published Version] View | Files available | DOI | WoS
 
[91]
2018 | Published | Journal Article | IST-REx-ID: 318 | OA
A fat lot of good for wound healing
A.M. Casano, M.K. Sixt, Developmental Cell 44 (2018) 405–406.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[90]
2018 | Published | Journal Article | IST-REx-ID: 437 | OA
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. de Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
[Published Version] View | Files available | DOI | WoS
 
[89]
2018 | Published | Journal Article | IST-REx-ID: 275 | OA
Lymphatic exosomes promote dendritic cell migration along guidance cues
M. Brown, L. Johnson, D. Leone, P. Májek, K. Vaahtomeri, D. Senfter, N. Bukosza, H. Schachner, G. Asfour, B. Langer, R. Hauschild, K. Parapatics, Y. Hong, K. Bennett, R. Kain, M. Detmar, M.K. Sixt, D. Jackson, D. Kerjaschki, Journal of Cell Biology 217 (2018) 2205–2221.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[88]
2018 | Published | Book Chapter | IST-REx-ID: 153
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
View | DOI | WoS | PubMed | Europe PMC
 
[87]
2018 | Published | Journal Article | IST-REx-ID: 5858 | OA
Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data
S. Hross, F.J. Theis, M.K. Sixt, J. Hasenauer, Journal of the Royal Society Interface 15 (2018).
[Published Version] View | Files available | DOI | WoS
 
[86]
2018 | Published | Journal Article | IST-REx-ID: 5861 | OA
The cell sets the tone
J.H. Alanko, M.K. Sixt, ELife 7 (2018).
[Published Version] View | Files available | DOI | WoS
 
[85]
2018 | Published | Journal Article | IST-REx-ID: 15 | OA
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[84]
2018 | Published | Journal Article | IST-REx-ID: 402 | OA
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[83]
2017 | Published | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
View | DOI
 
[82]
2017 | Published | Journal Article | IST-REx-ID: 1161 | OA
Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) R24–R25.
[Published Version] View | DOI | Download Published Version (ext.) | WoS
 
[81]
2017 | Published | Journal Article | IST-REx-ID: 569 | OA
Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. Reversat, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
[80]
2017 | Published | Journal Article | IST-REx-ID: 571
Migrating platelets are mechano scavengers that collect and bundle bacteria
Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
View | DOI
 
[79]
2017 | Published | Journal Article | IST-REx-ID: 659 | OA
FMNL formins boost lamellipodial force generation
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
[Published Version] View | Files available | DOI
 
[78]
2017 | Published | Journal Article | IST-REx-ID: 668 | OA
Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
[Published Version] View | Files available | DOI
 
[77]
2017 | Published | Journal Article | IST-REx-ID: 672 | OA
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
[Published Version] View | Files available | DOI
 
[76]
2017 | Published | Journal Article | IST-REx-ID: 694 | OA
A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[75]
2017 | Published | Journal Article | IST-REx-ID: 727
Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
View | DOI | WoS
 
[74]
2017 | Published | Journal Article | IST-REx-ID: 679 | OA
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[73]
2017 | Published | Journal Article | IST-REx-ID: 664
The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
View | Files available | DOI
 
[72]
2016 | Published | Journal Article | IST-REx-ID: 1137 | OA
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Salzer E, Çaǧdaş D, Hons M, Mace E, Garncarz W, Petronczki O, Platzer R, Pfajfer L, Bilic I, Ban S, Willmann K, Mukherjee M, Supper V, Hsu H, Banerjee P, Sinha P, Mcclanahan F, Zlabinger G, Pickl W, Gribben J, Stockinger H, Bennett K, Huppa J, Dupré L, Sanal Ö, Jäger U, Sixt MK, Tezcan I, Orange J, Boztug K. 2016. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology. 17(12), 1352–1360.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[71]
2016 | Published | Journal Article | IST-REx-ID: 1142 | OA
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger M, Radic Sarikas B, Lardeau C, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth S, Decker T, Bennett K, Kubicek S, Sixt MK, Superti Furga G, Knapp S. 2016. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology. 17(12), 1361–1372.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
[70]
2016 | Published | Journal Article | IST-REx-ID: 1150
A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
View | DOI
 
[69]
2016 | Published | Journal Article | IST-REx-ID: 1201
Formin’ a nuclear protection
J. Renkawitz, M.K. Sixt, Cell 167 (2016) 1448–1449.
View | DOI
 
[68]
2016 | Published | Journal Article | IST-REx-ID: 1490 | OA
Intralymphatic CCL21 promotes tissue egress of dendritic cells through afferent lymphatic vessels
E. Russo, A. Teijeira, K. Vaahtomeri, A. Willrodt, J. Bloch, M. Nitschké, L. Santambrogio, D. Kerjaschki, M.K. Sixt, C. Halin, Cell Reports 14 (2016) 1723–1734.
[Published Version] View | Files available | DOI
 
[67]
2016 | Published | Journal Article | IST-REx-ID: 1154 | OA
A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
[Published Version] View | Files available | DOI
 
[66]
2016 | Published | Journal Article | IST-REx-ID: 1597
Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
View | DOI | PubMed | Europe PMC
 
[65]
2016 | Published | Journal Article | IST-REx-ID: 1285
Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
View | DOI
 
[64]
2016 | Published | Journal Article | IST-REx-ID: 1599 | OA
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[63]
2016 | Published | Journal Article | IST-REx-ID: 1321 | OA
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
[Submitted Version] View | Files available | DOI
 
[62]
2015 | Published | Journal Article | IST-REx-ID: 1676
Editorial overview: Cell adhesion and migration
M.K. Sixt, E. Raz, Current Opinion in Cell Biology 36 (2015) 4–6.
View | DOI
 
[61]
2015 | Published | Journal Article | IST-REx-ID: 1686
Fragmented communication between immune cells: Neutrophils blaze a trail with migratory cues for T cells to follow to sites of infection
E. Kiermaier, M.K. Sixt, Science 349 (2015) 1055–1056.
View | DOI
 
[60]
2015 | Published | Journal Article | IST-REx-ID: 477
The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst, E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
View | DOI
 
[59]
2015 | Published | Journal Article | IST-REx-ID: 1560
The lymph node filter revealed
M. Hons, M.K. Sixt, Nature Immunology 16 (2015) 338–340.
View | DOI
 
[58]
2015 | Published | Journal Article | IST-REx-ID: 1561
A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors
K. Heger, M. Kober, D. Rieß, C. Drees, I. de Vries, A. Bertossi, A. Roers, M.K. Sixt, M. Schmidt Supprian, European Journal of Immunology 45 (2015) 1614–1620.
View | DOI
 
[57]
2015 | Published | Journal Article | IST-REx-ID: 1575 | OA
Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells
M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin, E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt, J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications 6 (2015).
[Published Version] View | Files available | DOI
 
[56]
2015 | Published | Journal Article | IST-REx-ID: 1537 | OA
Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
V. Ruprecht, S. Wieser, A. Callan Jones, M. Smutny, H. Morita, K. Sako, V. Barone, M. Ritsch Marte, M.K. Sixt, R. Voituriez, C.-P.J. Heisenberg, Cell 160 (2015) 673–685.
[Published Version] View | Files available | DOI
 
[55]
2015 | Published | Journal Article | IST-REx-ID: 1687 | OA
Navigating in tissue mazes: Chemoattractant interpretation in complex environments
M. Sarris, M.K. Sixt, Current Opinion in Cell Biology 36 (2015) 93–102.
[Published Version] View | Files available | DOI
 
[54]
2015 | Published | Journal Article | IST-REx-ID: 1618 | OA
Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites
Veldkamp C, Kiermaier E, Gabel Eissens S, Gillitzer M, Lippner D, Disilvio F, Mueller C, Wantuch P, Chaffee G, Famiglietti M, Zgoba D, Bailey A, Bah Y, Engebretson S, Graupner D, Lackner E, Larosa V, Medeiros T, Olson M, Phillips A, Pyles H, Richard A, Schoeller S, Touzeau B, Williams L, Sixt MK, Peterson F. 2015. Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites. Biochemistry. 54(27), 4163–4166.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[53]
2015 | Published | Journal Article | IST-REx-ID: 1553
Actin flows mediate a universal coupling between cell speed and cell persistence
P. Maiuri, J. Rupprecht, S. Wieser, V. Ruprecht, O. Bénichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.-P.J. Heisenberg, C. Lage Crespo, F. Lautenschlaeger, M. Le Berre, A. Lennon Duménil, M. Raab, H. Thiam, M. Piel, M.K. Sixt, R. Voituriez, Cell 161 (2015) 374–386.
View | DOI
 
[52]
2014 | Published | Journal Article | IST-REx-ID: 1877
Physiology: Relax and come in
M.K. Sixt, K. Vaahtomeri, Nature 514 (2014) 441–442.
View | DOI
 
[51]
2014 | Published | Journal Article | IST-REx-ID: 1910
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2
S. Konradi, N. Yasmin, D. Haslwanter, M. Weber, B. Gesslbauer, M.K. Sixt, H. Strobl, European Journal of Immunology 44 (2014) 553–560.
View | DOI
 
[50]
2014 | Published | Journal Article | IST-REx-ID: 2158 | OA
New paradigms in the establishment and maintenance of gradients during directed cell migration
R. Majumdar, M.K. Sixt, C. Parent, Current Opinion in Cell Biology 30 (2014) 33–40.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[49]
2014 | Published | Journal Article | IST-REx-ID: 2214 | OA
Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects
L. Stoler Barak, C. Moussion, E. Shezen, M. Hatzav, M.K. Sixt, R. Alon, PLoS One 9 (2014).
[Published Version] View | Files available | DOI
 
[48]
2014 | Published | Journal Article | IST-REx-ID: 2242
A miR-155-dependent microRNA hierarchy in dendritic cell maturation and macrophage activation
A. Dueck, A. Eichner, M.K. Sixt, G. Meister, FEBS Letters 588 (2014) 632–640.
View | DOI
 
[47]
2013 | Published | Book Chapter | IST-REx-ID: 10900
Live Cell Imaging of Chemotactic Dendritic Cell Migration in Explanted Mouse Ear Preparations
M. Weber, M.K. Sixt, in:, A. Cardona, E. Ubogu (Eds.), Chemokines, Humana Press, Totowa, NJ, 2013, pp. 215–226.
View | DOI | PubMed | Europe PMC
 
[46]
2013 | Published | Journal Article | IST-REx-ID: 2830
A conduit to amplify innate immunity
C. Moussion, M.K. Sixt, Immunity 38 (2013) 853–854.
View | DOI
 
[45]
2013 | Published | Journal Article | IST-REx-ID: 522
Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells
E. Fuertbauer, J. Zaujec, P. Uhrin, I. Raab, M. Weber, H. Schachner, M. Bauer, G. Schütz, B. Binder, M.K. Sixt, D. Kerjaschki, H. Stockinger, Immunology Letters 154 (2013) 31–41.
View | DOI
 
[44]
2013 | Published | Journal Article | IST-REx-ID: 2839 | OA
Interstitial dendritic cell guidance by haptotactic chemokine gradients
M. Weber, R. Hauschild, J. Schwarz, C. Moussion, I. de Vries, D. Legler, S. Luther, M.T. Bollenbach, M.K. Sixt, Science 339 (2013) 328–332.
[Published Version] View | DOI | Download Published Version (ext.)
 
[43]
2012 | Published | Journal Article | IST-REx-ID: 506 | OA
Cell migration: Fibroblasts find a new way to get ahead
M.K. Sixt, Journal of Cell Biology 197 (2012) 347–349.
[Published Version] View | Files available | DOI
 
[42]
2012 | Published | Journal Article | IST-REx-ID: 3158 | OA
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
H. Schachtner, A. Li, D. Stevenson, S. Calaminus, S. Thomas, S. Watson, M.K. Sixt, R. Wedlich Söldner, D. Strathdee, L. Machesky, European Journal of Cell Biology 91 (2012) 923–929.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[41]
2011 | Published | Journal Article | IST-REx-ID: 491
Setting the clock for recirculating lymphocytes
A. Eichner, M.K. Sixt, Science Signaling 4 (2011).
View | DOI
 
[40]
2011 | Published | Journal Article | IST-REx-ID: 518 | OA
CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells
D. Schraivogel, L. Weinmann, D. Beier, G. Tabatabai, A. Eichner, J. Zhu, M. Anton, M.K. Sixt, M. Weller, C. Beier, G. Meister, EMBO Journal 30 (2011) 4309–4322.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[39]
2011 | Published | Journal Article | IST-REx-ID: 3371 | OA
Cells on the move in Philadelphia
M.K. Sixt, C. Parent, Molecular Biology and Evolution 22 (2011) 724.
[Published Version] View | Files available | DOI
 
[38]
2011 | Published | Journal Article | IST-REx-ID: 3385
Interstitial locomotion of leukocytes
M.K. Sixt, Immunology Letters 138 (2011) 32–34.
View | DOI
 
[37]
2011 | Published | Journal Article | IST-REx-ID: 3392
In vivo analysis of uropod function during physiological T cell trafficking
S. Soriano, M. Hons, K. Schumann, V. Kumar, T. Dennier, R. Lyck, M.K. Sixt, J. Stein, Journal of Immunology 187 (2011) 2356–2364.
View | DOI
 
[36]
2011 | Published | Journal Article | IST-REx-ID: 3505 | OA
In vitro analysis of chemotactic leukocyte migration in 3D environments
M.K. Sixt, T. Lämmermann, Cell Migration 769 (2011) 149–165.
[Published Version] View | DOI | Download Published Version (ext.)
 
[35]
2010 | Published | Journal Article | IST-REx-ID: 3956
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
S. Nourshargh, P. Hordijk, M.K. Sixt, Nature Reviews Molecular Cell Biology 11 (2010) 366–378.
View | DOI
 
[34]
2010 | Published | Journal Article | IST-REx-ID: 3957
Lifeact mice for studying F-actin dynamics
J. Riedl, K. Flynn, A. Raducanu, F.R. Gärtner, G. Beck, M. Bosl, F. Bradke, S. Massberg, A. Aszodi, M.K. Sixt, R. Wedlich Söldner, Nature Methods 7 (2010) 168–169.
View | DOI
 
[33]
2010 | Published | Journal Article | IST-REx-ID: 3958
Extracellular matrix in multiple sclerosis lesions: fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells
H. Mohan, M. Krumbholz, R. Sharma, S. Eisele, A. Junker, M.K. Sixt, J. Newcombe, H. Wekerle, R. Hohlfeld, H. Lassmann, E. Meinl, Brain Pathology 20 (2010) 966–975.
View | DOI
 
[32]
2010 | Published | Journal Article | IST-REx-ID: 3959
Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells
K. Schumann, T. Lämmermann, M. Bruckner, D. Legler, J. Polleux, J. Spatz, G. Schuler, R. Förster, M. Lutz, L. Sorokin, M.K. Sixt, Immunity 32 (2010) 703–713.
View | DOI
 
[31]
2010 | Published | Journal Article | IST-REx-ID: 3960 | OA
MEK signalling tunes actin treadmilling for interstitial lymphocyte migration
M. Weber, M.K. Sixt, EMBO Journal 29 (2010) 2861–2863.
View | DOI | Download (ext.)
 
[30]
2010 | Published | Journal Article | IST-REx-ID: 3961
Mechanisms of force generation and force transmission during interstitial leukocyte migration
J. Renkawitz, M.K. Sixt, EMBO Reports 11 (2010) 744–750.
View | DOI
 
[29]
2009 | Published | Journal Article | IST-REx-ID: 3946 | OA
Analogies in the evolution of individual and social immunity
S. Cremer, M.K. Sixt, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 (2009) 129–142.
View | DOI | Download None (ext.)
 
[28]
2009 | Published | Journal Article | IST-REx-ID: 3947
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration (Plenary Paper)
T. Lämmermann, J. Renkawitz, X. Wu, K. Hirsch, C. Brakebusch, M.K. Sixt, Blood 113 (2009) 5703–5710.
View | DOI
 
[27]
2009 | Published | Journal Article | IST-REx-ID: 3948
β1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity
M. Bauer, C. Brakebusch, C. Coisne, M.K. Sixt, H. Wekerle, B. Engelhardt, R. Fässler, PNAS 106 (2009) 1920–1925.
View | DOI
 
[26]
2009 | Published | Journal Article | IST-REx-ID: 3949
Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells
T. Quast, B. Tappertzhofen, C. Schild, J. Grell, N. Czeloth, R. Förster, R. Alon, L. Fraemohs, K. Dreck, C. Weber, T. Lämmermann, M.K. Sixt, W. Kolanus, Blood 113 (2009) 5801–5810.
View | DOI
 
[25]
2009 | Published | Journal Article | IST-REx-ID: 3950
Kindlin-3 is required for β2 integrin-mediated leukocyte adhesion to endothelial cells
M. Moser, M. Bauer, S. Schmid, R. Ruppert, S. Schmidt, M.K. Sixt, H. Wang, M. Sperandio, R. Fässler, Nature Medicine 15 (2009) 300–305.
View | DOI
 
[24]
2009 | Published | Journal Article | IST-REx-ID: 3951
Mechanical modes of 'amoeboid' cell migration
T. Lämmermann, M.K. Sixt, Current Opinion in Cell Biology 21 (2009) 636–644.
View | DOI
 
[23]
2009 | Published | Journal Article | IST-REx-ID: 3952
A fundamental role of mAbp1 in neutrophils: impact on β(2) integrin-mediated phagocytosis and adhesion in vivo
J. Schymeinsky, R. Gerstl, I. Mannigel, K. Niedung, D. Frommhold, K. Panthel, J. Heesemann, M.K. Sixt, T. Quast, W. Kolanus, A. Mocsai, J. Wienands, M. Sperandio, B. Walzog, Blood 114 (2009) 4209–4220.
View | DOI
 
[22]
2009 | Published | Journal Article | IST-REx-ID: 3953
The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo
A. Wolf, K. Eller, R. Zeiser, C. Dürr, U. Gerlach, M.K. Sixt, L. Markut, G. Gastl, A. Rosenkranz, D. Wolf, Journal of Immunology 183 (2009) 3751–3760.
View | DOI
 
[21]
2009 | Published | Journal Article | IST-REx-ID: 3954
Adaptive force transmission in amoeboid cell migration
J. Renkawitz, K. Schumann, M. Weber, T. Lämmermann, H. Pflicke, M. Piel, J. Polleux, J. Spatz, M.K. Sixt, Nature Cell Biology 11 (2009) 1438–1443.
View | DOI
 
[20]
2009 | Published | Journal Article | IST-REx-ID: 3955
Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
H. Pflicke, M.K. Sixt, The Journal of Experimental Medicine 206 (2009) 2925–2935.
View | DOI
 
[19]
2008 | Published | Journal Article | IST-REx-ID: 3939
The microanatomy of T-cell responses
T. Lämmermann, M.K. Sixt, Immunological Reviews 221 (2008) 26–43.
View | DOI
 
[18]
2008 | Published | Journal Article | IST-REx-ID: 3940
The extracellular matrix of the spleen as a potential organizer of immune cell compartments
Z. Lokmic, T. Lämmermann, M.K. Sixt, S. Cardell, R. Hallmann, L. Sorokin, Seminars in Immunology 20 (2008) 4–13.
View | DOI
 
[17]
2008 | Published | Journal Article | IST-REx-ID: 3941
Rapid leukocyte migration by integrin-independent flowing and squeezing
T. Lämmermann, B. Bader, S. Monkley, T. Worbs, R. Wedlich Söldner, K. Hirsch, M. Keller, R. Förster, D. Critchley, R. Fässler, M.K. Sixt, Nature 453 (2008) 51–55.
View | DOI
 
[16]
2008 | Published | Journal Article | IST-REx-ID: 3942
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation
D. Frommhold, A. Ludwig, M.G. Bixel, A. Zarbock, I. Babushkina, M. Weissinger, S. Cauwenberghs, L. Ellies, J. Marth, A. Beck Sickinger, M.K. Sixt, B. Lange Sperandio, A. Zernecke, E. Brandt, C. Weber, D. Vestweber, K. Ley, M. Sperandio, The Journal of Experimental Medicine 205 (2008) 1435–1446.
View | DOI
 
[15]
2008 | Published | Journal Article | IST-REx-ID: 3943
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
K. Kessenbrock, L. Fröhlich, M.K. Sixt, T. Lämmermann, H. Pfister, A. Bateman, A. Belaaouaj, J. Ring, M. Ollert, R. Fässler, D. Jenne, The Journal of Clinical Investigation 118 (2008) 2438–2447.
View | DOI
 
[14]
2008 | Published | Journal Article | IST-REx-ID: 3944
Lifeact: a versatile marker to visualize F-actin
J. Riedl, A. Crevenna, K. Kessenbrock, J. Yu, D. Neukirchen, M. Bista, F. Bradke, D. Jenne, T. Holak, Z. Werb, M.K. Sixt, R. Wedlich Soldner, Nature Methods 5 (2008) 605–607.
View | DOI
 
[13]
2008 | Published | Journal Article | IST-REx-ID: 3945
The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1
C. Tripp, B. Haid, V. Flacher, M.K. Sixt, H. Peter, J. Farkas, R. Gschwentner, L. Sorokin, N. Romani, P. Stoitzner, Immunobiology 213 (2008) 715–28.
View | DOI
 
[12]
2007 | Published | Journal Article | IST-REx-ID: 3937
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces
E. Woolf, I. Grigorova, A. Sagiv, V. Grabovsky, S. Feigelson, Z. Shulman, T. Hartmann, M.K. Sixt, J. Cyster, R. Alon, Nature Immunology 8 (2007) 1076–1085.
View | DOI
 
[11]
2007 | Published | Journal Article | IST-REx-ID: 3938
RhoH is important for positive thymocyte selection and T-cell receptor signaling
T. Dorn, U. Kuhn, G. Bungartz, S. Stiller, M. Bauer, J. Ellwart, T. Peters, K. Scharffetter Kochanek, M. Semmrich, M. Laschinger, B. Holzmann, W. Klinkert, P. Straten, T. Køllgaard, M.K. Sixt, C. Brakebusch, Blood 109 (2007) 2346–2355.
View | DOI
 
[10]
2006 | Published | Journal Article | IST-REx-ID: 3932
EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor
E. Henic, M.K. Sixt, S. Hansson, G. Høyer Hansen, B. Casslén, Gynecologic Oncology 101 (2006) 28–39.
View | DOI
 
[9]
2006 | Published | Journal Article | IST-REx-ID: 3934
Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules
M. Drumea Mirancea, J. Wessels, C. Müller, M. Essl, J. Eble, E. Tolosa, M. Koch, D. Reinhardt, M.K. Sixt, L. Sorokin, Y. Stierhof, H. Schwarz, G. Klein, Journal of Cell Science 119 (2006) 1396–1405.
View | DOI
 
[8]
2006 | Published | Journal Article | IST-REx-ID: 3935
γ-Parvin is dispensable for hematopoiesis, leukocyte trafficking, and T-cell-dependent antibody response
H. Chu, I. Thievessen, M.K. Sixt, T. Lämmermann, A. Waisman, A. Braun, A. Noegel, R. Fässler, Molecular and Cellular Biology 26 (2006) 1817–1825.
View | DOI
 
[7]
2006 | Published | Journal Article | IST-REx-ID: 3936
β1 integrins: zip codes and signaling relay for blood cells
M.K. Sixt, M. Bauer, T. Lämmermann, R. Fässler, Current Opinion in Cell Biology 18 (2006) 482–490.
View | DOI
 
[6]
2005 | Published | Journal Article | IST-REx-ID: 3933
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
M.K. Sixt, N. Kanazawa, M. Selg, T. Samson, G. Roos, D. Reinhardt, R. Pabst, M. Lutz, L. Sorokin, Immunity 22 (2005) 19–29.
View | DOI
 
[5]
2004 | Published | Journal Article | IST-REx-ID: 3929
HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane
V. Witte, B. Laffert, O. Rosorius, P. Lischka, K. Blume, G. Galler, A. Stilper, D. Willbold, P. D’Aloja, M.K. Sixt, J. Kolanus, M. Ott, W. Kolanus, G. Schuler, A. Baur, Molecular Cell 13 (2004) 179–190.
View | DOI
 
[4]
2004 | Published | Journal Article | IST-REx-ID: 3931
Neurocan-GFP fusion protein: a new approach to detect hyaluronan on tissue sections and living cells
H. Zhang, S. Baader, M.K. Sixt, J. Kappler, U. Rauch, Journal of Histochemistry and Cytochemistry 52 (2004) 915–922.
View | DOI
 
[3]
2001 | Published | Journal Article | IST-REx-ID: 3927 | OA
TNF-α-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis
D. Wolf, R. Hallmann, G. Sass, M.K. Sixt, S. Küsters, B. Fregien, C. Trautwein, G. Tiegs, Journal of Immunology 166 (2001) 1300–1307.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[2]
2001 | Published | Journal Article | IST-REx-ID: 3928 | OA
Cell adhesion and migration properties of β2-integrin negative polymorphonuclear granulocytes on defined extracellular matrix molecules. Relevance for leukocyte extravasation
M.K. Sixt, R. Hallmann, O. Wendler, K. Scharffetter Kochanek, L. Sorokin, Journal of Biological Chemistry 276 (2001) 18878–18887.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[1]
2001 | Published | Journal Article | IST-REx-ID: 3930 | OA
Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis
M.K. Sixt, B. Engelhardt, F. Pausch, R. Hallmann, O. Wendler, L. Sorokin, Journal of Cell Biology 153 (2001) 933–946.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
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16 Grants


The role of polysialic acid in T cell immunity

2023-04-01 – 2026-03-31
Austrian Science Fund

Einfluss der Chemokinpräsentation auf das Reaktionsmuster von Leukozyten (SPP Si-1323/2-1)

2011-01-01 – 2013-01-15
Deutsche Forschungsgemeinschaft

Zytoskelettdynamik und Kraftgenerierung wandernder Leukozyten (Si-1323/1-3)

2010-11-01 – 2012-03-15
Deutsche Forschungsgemeinschaft

Role of the WAVE-complex in the haematopoietic System (SPP Si-1323/3-1)

2010-11-01 – 2013-10-31
Deutsche Forschungsgemeinschaft

Stromal Cell-immune Cell Interactions in Health and Disease (STROMA)

2012-01-01 – 2015-12-31
European Commission

Cytoskeletal force generation and force transduction of migrating leukocytes

2011-08-01 – 2016-12-31
Austrian Science Fund

Cell migration in complex environments: from in vivo experiments to theoretical models

2011-11-01 – 2015-04-30
Human Frontier Science Program

Cytoskeletal force generation and force transduction of migrating leukocytes (LeukocyteForces)

2012-04-01 – 2017-03-31
European Research Council

Role of the WAVE-complex in the haematopoietic System (SI 1323/3-2)

2013-11-01 – 2016-10-31
Deutsche Forschungsgemeinschaft

Nano-Analytics of Cellular Systems (NanoCell)

2017-03-01 – 2020-02-29
Austrian Science Fund

Modeling of Polarization and Motility of Leukocytes in Three-Dimensional Environments

2014-03-01 – 2018-02-28
Vienna Science and Technology Fund

Cellular Navigation Along Spatial Gradients (GradientSensing)

2017-04-01 – 2022-03-31
European Research Council

Mechanical adaptation of lamellipodial actin

2017-03-01 – 2020-02-29
Austrian Science Fund

Nano-Analytics of Cellular Systems (NanoCell)

2018-03-01 – 2023-08-31
Austrian Science Fund

Pushing from within: Control of cell shape, integrity and motility by cytoskeletal pushing forces (PushingCell)

2023-05-01 – 2029-04-30
European Research Council

ImMuNet: Decoding the Immunological Microtubule Network (lmMuNet)

2023-10-01 – 2027-09-30
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

131 Publications

Mark all

[131]
2025 | Epub ahead of print | Journal Article | IST-REx-ID: 19928 | OA
Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis
Gawish R, Varada R, Deckert F, Hladik A, Steinbichl L, Cimatti L, Milanovic K, Jain M, Torgasheva N, Tanzer A, De Paepe K, Van De Wiele T, Hausmann B, Lang M, Pechhacker M, Ibrahim N, de Vries I, Brostjan C, Sixt MK, Gasche C, Boon L, Berry D, Jantsch MF, Pereira FC, Vesely C. 2025. Filamin A editing in myeloid cells reduces intestinal inflammation and protects from colitis. Journal of Experimental Medicine. 222(9), e20240109.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[130]
2025 | Published | Journal Article | IST-REx-ID: 20082 | OA | PlanS
Migrating immune cells globally coordinate protrusive forces
P. Dos Reis Rodrigues, M. Avellaneda Sarrió, N. Canigova, F.R. Gärtner, K. Vaahtomeri, M. Riedl, I. de Vries, J. Merrin, R. Hauschild, Y. Fukui, A. Juanes Garcia, M.K. Sixt, Nature Immunology 26 (2025) 1258–1266.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[129]
2024 | Published | Journal Article | IST-REx-ID: 17279
Rescuing T cells from stiff tumors
M. Avellaneda Sarrió, M.K. Sixt, Cell Chemical Biology 31 (2024) 1242–1243.
View | DOI | PubMed | Europe PMC
 
[128]
2024 | Published | Journal Article | IST-REx-ID: 17284 | OA
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis
Gärtner FR, Ishikawa-Ankerhold H, Stutte S, Fu W, Weitz J, Dueck A, Nelakuditi B, Fumagalli V, Van Den Heuvel D, Belz L, Sobirova G, Zhang Z, Titova A, Navarro AM, Pekayvaz K, Lorenz M, Von Baumgarten L, Kranich J, Straub T, Popper B, Zheden V, Kaufmann W, Guo C, Piontek G, Von Stillfried S, Boor P, Colonna M, Clauß S, Schulz C, Brocker T, Walzog B, Scheiermann C, Aird WC, Nerlov C, Stark K, Petzold T, Engelhardt S, Sixt MK, Hauschild R, Rudelius M, Oostendorp RAJ, Iannacone M, Heinig M, Massberg S. 2024. Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis. Nature. 631, 645–653.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[127]
2024 | Published | Journal Article | IST-REx-ID: 15146 | OA
Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix
B. Zens, F. Fäßler, J. Hansen, R. Hauschild, J. Datler, V.-V. Hodirnau, V. Zheden, J.H. Alanko, M.K. Sixt, F.K. Schur, Journal of Cell Biology 223 (2024).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[126]
2024 | Published | Journal Article | IST-REx-ID: 15408 | OA
Integrin β1–mediated mast cell immune-surveillance of blood vessel content
K. Link, L. Muhandes, A. Polikarpova, T. Lämmermann, M.K. Sixt, R. Fässler, A. Roers, Journal of Allergy and Clinical Immunology 154 (2024) 745–753.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[125]
2024 | Published | Journal Article | IST-REx-ID: 17191
Nuclear squeezing wakes up dendritic cells
S. Lembo, M.K. Sixt, Nature Immunology 25 (2024) 1131–1132.
View | DOI | PubMed | Europe PMC
 
[124]
2023 | Published | Book Chapter | IST-REx-ID: 13052
En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses
A.F. Leithner, J. Merrin, M.K. Sixt, in:, C. Baldari, M. Dustin (Eds.), The Immune Synapse, Springer Nature, New York, NY, 2023, pp. 137–147.
View | DOI | PubMed | Europe PMC
 
[123]
2023 | Published | Journal Article | IST-REx-ID: 14361 | OA
Synchronization in collectively moving inanimate and living active matter
M. Riedl, I.D. Mayer, J. Merrin, M.K. Sixt, B. Hof, Nature Communications 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[122]
2023 | Published | Journal Article | IST-REx-ID: 14555 | OA
The excitable nature of polymerizing actin and the Belousov-Zhabotinsky reaction
M. Riedl, M.K. Sixt, Frontiers in Cell and Developmental Biology 11 (2023).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[121]
2023 | Published | Journal Article | IST-REx-ID: 14274 | OA
CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
J.H. Alanko, M.C. Ucar, N. Canigova, J.A. Stopp, J. Schwarz, J. Merrin, E.B. Hannezo, M.K. Sixt, Science Immunology 8 (2023).
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[120]
2023 | Published | Journal Article | IST-REx-ID: 14360 | OA
Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
E. Sitarska, S.D. Almeida, M.S. Beckwith, J.A. Stopp, J. Czuchnowski, M. Siggel, R. Roessner, A. Tschanz, C. Ejsing, Y. Schwab, J. Kosinski, M.K. Sixt, A. Kreshuk, A. Erzberger, A. Diz-Muñoz, Nature Communications 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[119]
2022 | Published | Journal Article | IST-REx-ID: 12133
Principles of disease defence in organisms, superorganisms and societies
S. Cremer, M.K. Sixt, Nature Reviews Immunology 22 (2022) 713–714.
View | DOI | WoS | PubMed | Europe PMC
 
[118]
2022 | Published | Journal Article | IST-REx-ID: 11843 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[117]
2022 | Published | Journal Article | IST-REx-ID: 9794 | OA
Multitier mechanics control stromal adaptations in swelling lymph nodes
F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg, W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology 23 (2022) 1246–1255.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[116]
2022 | Published | Journal Article | IST-REx-ID: 12272 | OA
Plan your trip before you leave: The neutrophils’ search-and-run journey
J.A. Stopp, M.K. Sixt, Journal of Cell Biology 221 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[115]
2022 | Published | Journal Article | IST-REx-ID: 10703 | OA
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
F. Gaertner, P. Dos Reis Rodrigues, I. de Vries, M. Hons, J. Aguilera, M. Riedl, A.F. Leithner, S. Tasciyan, A. Kopf, J. Merrin, V. Zheden, W. Kaufmann, R. Hauschild, M.K. Sixt, Developmental Cell 57 (2022) 47–62.e9.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[114]
2021 | Published | Journal Article | IST-REx-ID: 10834 | OA
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | PubMed | Europe PMC
 
[113]
2021 | Published | Journal Article | IST-REx-ID: 9094 | OA
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[112]
2021 | Published | Journal Article | IST-REx-ID: 9259 | OA
Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[111]
2021 | Published | Journal Article | IST-REx-ID: 9294 | OA
Engaging the front wheels to drive through fibrous terrain
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[110]
2021 | Published | Journal Article | IST-REx-ID: 9822 | OA
Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[109]
2021 | Draft | Preprint | IST-REx-ID: 10316 | OA
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 
[108]
2020 | Published | Journal Article | IST-REx-ID: 7234 | OA
Partial loss of actin nucleator actin-related protein 2/3 activity triggers blebbing in primary T lymphocytes
P. Obeidy, L.A. Ju, S.H. Oehlers, N.S. Zulkhernain, Q. Lee, J.L. Galeano Niño, R.Y.Q. Kwan, S. Tikoo, L.L. Cavanagh, P. Mrass, A.J.L. Cook, S.P. Jackson, M. Biro, B. Roediger, M.K. Sixt, W. Weninger, Immunology and Cell Biology 98 (2020) 93–113.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[107]
2020 | Published | Journal Article | IST-REx-ID: 7909 | OA
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[106]
2020 | Published | Journal Article | IST-REx-ID: 8142 | OA
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
J.C. Montesinos López, A. Abuzeineh, A. Kopf, A. Juanes Garcia, K. Ötvös, J. Petrášek, M.K. Sixt, E. Benková, The Embo Journal 39 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[105]
2020 | Published | Journal Article | IST-REx-ID: 7875 | OA
Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[104]
2020 | Published | Journal Article | IST-REx-ID: 8132 | OA
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt MK, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. 2020. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology. 5(49), eabc3979.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[103]
2020 | Published | Journal Article | IST-REx-ID: 7623 | OA
Modeling adhesion-independent cell migration
G. Jankowiak, D. Peurichard, A. Reversat, C. Schmeiser, M.K. Sixt, Mathematical Models and Methods in Applied Sciences 30 (2020) 513–537.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | arXiv
 
[102]
2020 | Published | Journal Article | IST-REx-ID: 7876 | OA
T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[101]
2020 | Published | Journal Article | IST-REx-ID: 7885 | OA
Cellular locomotion using environmental topography
A. Reversat, F.R. Gärtner, J. Merrin, J.A. Stopp, S. Tasciyan, J.L. Aguilera Servin, I. de Vries, R. Hauschild, M. Hons, M. Piel, A. Callan-Jones, R. Voituriez, M.K. Sixt, Nature 582 (2020) 582–585.
[Preprint] View | Files available | DOI | Download Preprint (ext.) | WoS | PubMed | Europe PMC
 
[100]
2020 | Published | Journal Article | IST-REx-ID: 8190 | OA
Zena Werb (1945-2020): Cell biology in context
M.K. Sixt, A. Huttenlocher, The Journal of Cell Biology 219 (2020).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[99]
2019 | Published | Journal Article | IST-REx-ID: 6979
Gut homeostasis: Active migration of intestinal epithelial cells in tissue renewal
A. Kopf, M.K. Sixt, Current Biology 29 (2019) R1091–R1093.
View | DOI | WoS | PubMed | Europe PMC
 
[98]
2019 | Published | Journal Article | IST-REx-ID: 7009
Mechanisms of 3D cell migration
K. Yamada, M.K. Sixt, Nature Reviews Molecular Cell Biology 20 (2019) 738–752.
View | DOI | WoS | PubMed | Europe PMC
 
[97]
2019 | Published | Journal Article | IST-REx-ID: 7105 | OA
Persistent and polarized global actin flow is essential for directionality during cell migration
L. Yolland, M. Burki, S. Marcotti, A. Luchici, F.N. Kenny, J.R. Davis, E. Serna-Morales, J. Müller, M.K. Sixt, A. Davidson, W. Wood, L.J. Schumacher, R.G. Endres, M. Miodownik, B.M. Stramer, Nature Cell Biology 21 (2019) 1370–1381.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[96]
2019 | Published | Journal Article | IST-REx-ID: 6328 | OA
Nuclear positioning facilitates amoeboid migration along the path of least resistance
J. Renkawitz, A. Kopf, J.A. Stopp, I. de Vries, M.K. Driscoll, J. Merrin, R. Hauschild, E.S. Welf, G. Danuser, R. Fiolka, M.K. Sixt, Nature 568 (2019) 546–550.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | WoS | PubMed | Europe PMC
 
[95]
2019 | Published | Journal Article | IST-REx-ID: 6877
The neural crest pitches in to remove apoptotic debris
A. Kopf, M.K. Sixt, Cell 179 (2019) 51–53.
View | Files available | DOI | WoS | PubMed | Europe PMC
 
[94]
2018 | Published | Journal Article | IST-REx-ID: 5672 | OA
IgM's exit route
A. Reversat, M.K. Sixt, Journal of Experimental Medicine 215 (2018) 2959–2961.
[Published Version] View | Files available | DOI | WoS
 
[93]
2018 | Published | Journal Article | IST-REx-ID: 5992 | OA
On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility
S. Dolati, F. Kage, J. Mueller, M. Müsken, M. Kirchner, G. Dittmar, M.K. Sixt, K. Rottner, M. Falcke, Molecular Biology of the Cell 29 (2018) 2674–2686.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[92]
2018 | Published | Journal Article | IST-REx-ID: 6497 | OA
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+T cells
F. Moalli, X. Ficht, P. Germann, M. Vladymyrov, B. Stolp, I. de Vries, R. Lyck, J. Balmer, A. Fiocchi, M. Kreutzfeldt, D. Merkler, M. Iannacone, A. Ariga, M.H. Stoffel, J. Sharpe, M. Bähler, M.K. Sixt, A. Diz-Muñoz, J.V. Stein, The Journal of Experimental Medicine 2015 (2018) 1869–1890.
[Published Version] View | Files available | DOI | WoS
 
[91]
2018 | Published | Journal Article | IST-REx-ID: 318 | OA
A fat lot of good for wound healing
A.M. Casano, M.K. Sixt, Developmental Cell 44 (2018) 405–406.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[90]
2018 | Published | Journal Article | IST-REx-ID: 437 | OA
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
A.F. Leithner, J. Renkawitz, I. de Vries, R. Hauschild, H. Haecker, M.K. Sixt, European Journal of Immunology 48 (2018) 1074–1077.
[Published Version] View | Files available | DOI | WoS
 
[89]
2018 | Published | Journal Article | IST-REx-ID: 275 | OA
Lymphatic exosomes promote dendritic cell migration along guidance cues
M. Brown, L. Johnson, D. Leone, P. Májek, K. Vaahtomeri, D. Senfter, N. Bukosza, H. Schachner, G. Asfour, B. Langer, R. Hauschild, K. Parapatics, Y. Hong, K. Bennett, R. Kain, M. Detmar, M.K. Sixt, D. Jackson, D. Kerjaschki, Journal of Cell Biology 217 (2018) 2205–2221.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[88]
2018 | Published | Book Chapter | IST-REx-ID: 153
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J. Renkawitz, A. Reversat, A.F. Leithner, J. Merrin, M.K. Sixt, in:, Methods in Cell Biology, Academic Press, 2018, pp. 79–91.
View | DOI | WoS | PubMed | Europe PMC
 
[87]
2018 | Published | Journal Article | IST-REx-ID: 5858 | OA
Mechanistic description of spatial processes using integrative modelling of noise-corrupted imaging data
S. Hross, F.J. Theis, M.K. Sixt, J. Hasenauer, Journal of the Royal Society Interface 15 (2018).
[Published Version] View | Files available | DOI | WoS
 
[86]
2018 | Published | Journal Article | IST-REx-ID: 5861 | OA
The cell sets the tone
J.H. Alanko, M.K. Sixt, ELife 7 (2018).
[Published Version] View | Files available | DOI | WoS
 
[85]
2018 | Published | Journal Article | IST-REx-ID: 15 | OA
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M. Hons, A. Kopf, R. Hauschild, A.F. Leithner, F.R. Gärtner, J. Abe, J. Renkawitz, J. Stein, M.K. Sixt, Nature Immunology 19 (2018) 606–616.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[84]
2018 | Published | Journal Article | IST-REx-ID: 402 | OA
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M. Brown, F.P. Assen, A.F. Leithner, J. Abe, H. Schachner, G. Asfour, Z. Bagó Horváth, J. Stein, P. Uhrin, M.K. Sixt, D. Kerjaschki, Science 359 (2018) 1408–1411.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 
[83]
2017 | Published | Journal Article | IST-REx-ID: 674
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal to noise ratio and dependent on GRK6
J. Schwarz, V. Bierbaum, K. Vaahtomeri, R. Hauschild, M. Brown, I. de Vries, A.F. Leithner, A. Reversat, J. Merrin, T. Tarrant, M.T. Bollenbach, M.K. Sixt, Current Biology 27 (2017) 1314–1325.
View | DOI
 
[82]
2017 | Published | Journal Article | IST-REx-ID: 1161 | OA
Cell migration: Making the waves
J. Müller, M.K. Sixt, Current Biology 27 (2017) R24–R25.
[Published Version] View | DOI | Download Published Version (ext.) | WoS
 
[81]
2017 | Published | Journal Article | IST-REx-ID: 569 | OA
Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments
F. Spira, S. Cuylen Haering, S. Mehta, M. Samwer, A. Reversat, A. Verma, R. Oldenbourg, M.K. Sixt, D. Gerlich, ELife 6 (2017).
[Published Version] View | Files available | DOI
 
[80]
2017 | Published | Journal Article | IST-REx-ID: 571
Migrating platelets are mechano scavengers that collect and bundle bacteria
Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
View | DOI
 
[79]
2017 | Published | Journal Article | IST-REx-ID: 659 | OA
FMNL formins boost lamellipodial force generation
F. Kage, M. Winterhoff, V. Dimchev, J. Müller, T. Thalheim, A. Freise, S. Brühmann, J. Kollasser, J. Block, G.A. Dimchev, M. Geyer, H. Schnittler, C. Brakebusch, T. Stradal, M. Carlier, M.K. Sixt, J. Käs, J. Faix, K. Rottner, Nature Communications 8 (2017).
[Published Version] View | Files available | DOI
 
[78]
2017 | Published | Journal Article | IST-REx-ID: 668 | OA
Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion
M. Horsthemke, A. Bachg, K. Groll, S. Moyzio, B. Müther, S. Hemkemeyer, R. Wedlich Söldner, M.K. Sixt, S. Tacke, M. Bähler, P. Hanley, Journal of Biological Chemistry 292 (2017) 7258–7273.
[Published Version] View | Files available | DOI
 
[77]
2017 | Published | Journal Article | IST-REx-ID: 672 | OA
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K. Vaahtomeri, M. Brown, R. Hauschild, I. de Vries, A.F. Leithner, M. Mehling, W. Kaufmann, M.K. Sixt, Cell Reports 19 (2017) 902–909.
[Published Version] View | Files available | DOI
 
[76]
2017 | Published | Journal Article | IST-REx-ID: 694 | OA
A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity
A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[75]
2017 | Published | Journal Article | IST-REx-ID: 727
Load adaptation of lamellipodial actin networks
J. Mueller, G. Szep, M. Nemethova, I. de Vries, A. Lieber, C. Winkler, K. Kruse, J. Small, C. Schmeiser, K. Keren, R. Hauschild, M.K. Sixt, Cell 171 (2017) 188–200.
View | DOI | WoS
 
[74]
2017 | Published | Journal Article | IST-REx-ID: 679 | OA
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection
F. Ebner, V. Sedlyarov, S. Tasciyan, M. Ivin, F. Kratochvill, N. Gratz, L. Kenner, A. Villunger, M.K. Sixt, P. Kovarik, The Journal of Clinical Investigation 127 (2017) 2051–2065.
[Submitted Version] View | Files available | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[73]
2017 | Published | Journal Article | IST-REx-ID: 664
The dynamic cytokine niche
F.P. Assen, M.K. Sixt, Immunity 46 (2017) 519–520.
View | Files available | DOI
 
[72]
2016 | Published | Journal Article | IST-REx-ID: 1137 | OA
RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics
Salzer E, Çaǧdaş D, Hons M, Mace E, Garncarz W, Petronczki O, Platzer R, Pfajfer L, Bilic I, Ban S, Willmann K, Mukherjee M, Supper V, Hsu H, Banerjee P, Sinha P, Mcclanahan F, Zlabinger G, Pickl W, Gribben J, Stockinger H, Bennett K, Huppa J, Dupré L, Sanal Ö, Jäger U, Sixt MK, Tezcan I, Orange J, Boztug K. 2016. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nature Immunology. 17(12), 1352–1360.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[71]
2016 | Published | Journal Article | IST-REx-ID: 1142 | OA
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger M, Radic Sarikas B, Lardeau C, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth S, Decker T, Bennett K, Kubicek S, Sixt MK, Superti Furga G, Knapp S. 2016. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature Immunology. 17(12), 1361–1372.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 
[70]
2016 | Published | Journal Article | IST-REx-ID: 1150
A Radical Break Restraining Neutrophil Migration
J. Renkawitz, M.K. Sixt, Developmental Cell 38 (2016) 448–450.
View | DOI
 
[69]
2016 | Published | Journal Article | IST-REx-ID: 1201
Formin’ a nuclear protection
J. Renkawitz, M.K. Sixt, Cell 167 (2016) 1448–1449.
View | DOI
 
[68]
2016 | Published | Journal Article | IST-REx-ID: 1490 | OA
Intralymphatic CCL21 promotes tissue egress of dendritic cells through afferent lymphatic vessels
E. Russo, A. Teijeira, K. Vaahtomeri, A. Willrodt, J. Bloch, M. Nitschké, L. Santambrogio, D. Kerjaschki, M.K. Sixt, C. Halin, Cell Reports 14 (2016) 1723–1734.
[Published Version] View | Files available | DOI
 
[67]
2016 | Published | Journal Article | IST-REx-ID: 1154 | OA
A microfluidic device for measuring cell migration towards substrate bound and soluble chemokine gradients
J. Schwarz, V. Bierbaum, J. Merrin, T. Frank, R. Hauschild, M.T. Bollenbach, S. Tay, M.K. Sixt, M. Mehling, Scientific Reports 6 (2016).
[Published Version] View | Files available | DOI
 
[66]
2016 | Published | Journal Article | IST-REx-ID: 1597
Quantitative analysis of dendritic cell haptotaxis
J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.
View | DOI | PubMed | Europe PMC
 
[65]
2016 | Published | Journal Article | IST-REx-ID: 1285
Focal adhesion-independent cell migration
E. Paluch, I. Aspalter, M.K. Sixt, Annual Review of Cell and Developmental Biology 32 (2016) 469–490.
View | DOI
 
[64]
2016 | Published | Journal Article | IST-REx-ID: 1599 | OA
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition
E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[63]
2016 | Published | Journal Article | IST-REx-ID: 1321 | OA
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.
[Submitted Version] View | Files available | DOI
 
[62]
2015 | Published | Journal Article | IST-REx-ID: 1676
Editorial overview: Cell adhesion and migration
M.K. Sixt, E. Raz, Current Opinion in Cell Biology 36 (2015) 4–6.
View | DOI
 
[61]
2015 | Published | Journal Article | IST-REx-ID: 1686
Fragmented communication between immune cells: Neutrophils blaze a trail with migratory cues for T cells to follow to sites of infection
E. Kiermaier, M.K. Sixt, Science 349 (2015) 1055–1056.
View | DOI
 
[60]
2015 | Published | Journal Article | IST-REx-ID: 477
The serotonin receptor 5-HT7R regulates the morphology and migratory properties of dendritic cells
K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst, E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
View | DOI
 
[59]
2015 | Published | Journal Article | IST-REx-ID: 1560
The lymph node filter revealed
M. Hons, M.K. Sixt, Nature Immunology 16 (2015) 338–340.
View | DOI
 
[58]
2015 | Published | Journal Article | IST-REx-ID: 1561
A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors
K. Heger, M. Kober, D. Rieß, C. Drees, I. de Vries, A. Bertossi, A. Roers, M.K. Sixt, M. Schmidt Supprian, European Journal of Immunology 45 (2015) 1614–1620.
View | DOI
 
[57]
2015 | Published | Journal Article | IST-REx-ID: 1575 | OA
Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells
M. Chabaud, M. Heuzé, M. Bretou, P. Vargas, P. Maiuri, P. Solanes, M. Maurin, E. Terriac, M. Le Berre, D. Lankar, T. Piolot, R. Adelstein, Y. Zhang, M.K. Sixt, J. Jacobelli, O. Bénichou, R. Voituriez, M. Piel, A. Lennon Duménil, Nature Communications 6 (2015).
[Published Version] View | Files available | DOI
 
[56]
2015 | Published | Journal Article | IST-REx-ID: 1537 | OA
Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
V. Ruprecht, S. Wieser, A. Callan Jones, M. Smutny, H. Morita, K. Sako, V. Barone, M. Ritsch Marte, M.K. Sixt, R. Voituriez, C.-P.J. Heisenberg, Cell 160 (2015) 673–685.
[Published Version] View | Files available | DOI
 
[55]
2015 | Published | Journal Article | IST-REx-ID: 1687 | OA
Navigating in tissue mazes: Chemoattractant interpretation in complex environments
M. Sarris, M.K. Sixt, Current Opinion in Cell Biology 36 (2015) 93–102.
[Published Version] View | Files available | DOI
 
[54]
2015 | Published | Journal Article | IST-REx-ID: 1618 | OA
Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites
Veldkamp C, Kiermaier E, Gabel Eissens S, Gillitzer M, Lippner D, Disilvio F, Mueller C, Wantuch P, Chaffee G, Famiglietti M, Zgoba D, Bailey A, Bah Y, Engebretson S, Graupner D, Lackner E, Larosa V, Medeiros T, Olson M, Phillips A, Pyles H, Richard A, Schoeller S, Touzeau B, Williams L, Sixt MK, Peterson F. 2015. Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites. Biochemistry. 54(27), 4163–4166.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[53]
2015 | Published | Journal Article | IST-REx-ID: 1553
Actin flows mediate a universal coupling between cell speed and cell persistence
P. Maiuri, J. Rupprecht, S. Wieser, V. Ruprecht, O. Bénichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.-P.J. Heisenberg, C. Lage Crespo, F. Lautenschlaeger, M. Le Berre, A. Lennon Duménil, M. Raab, H. Thiam, M. Piel, M.K. Sixt, R. Voituriez, Cell 161 (2015) 374–386.
View | DOI
 
[52]
2014 | Published | Journal Article | IST-REx-ID: 1877
Physiology: Relax and come in
M.K. Sixt, K. Vaahtomeri, Nature 514 (2014) 441–442.
View | DOI
 
[51]
2014 | Published | Journal Article | IST-REx-ID: 1910
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2
S. Konradi, N. Yasmin, D. Haslwanter, M. Weber, B. Gesslbauer, M.K. Sixt, H. Strobl, European Journal of Immunology 44 (2014) 553–560.
View | DOI
 
[50]
2014 | Published | Journal Article | IST-REx-ID: 2158 | OA
New paradigms in the establishment and maintenance of gradients during directed cell migration
R. Majumdar, M.K. Sixt, C. Parent, Current Opinion in Cell Biology 30 (2014) 33–40.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[49]
2014 | Published | Journal Article | IST-REx-ID: 2214 | OA
Blood vessels pattern heparan sulfate gradients between their apical and basolateral aspects
L. Stoler Barak, C. Moussion, E. Shezen, M. Hatzav, M.K. Sixt, R. Alon, PLoS One 9 (2014).
[Published Version] View | Files available | DOI
 
[48]
2014 | Published | Journal Article | IST-REx-ID: 2242
A miR-155-dependent microRNA hierarchy in dendritic cell maturation and macrophage activation
A. Dueck, A. Eichner, M.K. Sixt, G. Meister, FEBS Letters 588 (2014) 632–640.
View | DOI
 
[47]
2013 | Published | Book Chapter | IST-REx-ID: 10900
Live Cell Imaging of Chemotactic Dendritic Cell Migration in Explanted Mouse Ear Preparations
M. Weber, M.K. Sixt, in:, A. Cardona, E. Ubogu (Eds.), Chemokines, Humana Press, Totowa, NJ, 2013, pp. 215–226.
View | DOI | PubMed | Europe PMC
 
[46]
2013 | Published | Journal Article | IST-REx-ID: 2830
A conduit to amplify innate immunity
C. Moussion, M.K. Sixt, Immunity 38 (2013) 853–854.
View | DOI
 
[45]
2013 | Published | Journal Article | IST-REx-ID: 522
Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells
E. Fuertbauer, J. Zaujec, P. Uhrin, I. Raab, M. Weber, H. Schachner, M. Bauer, G. Schütz, B. Binder, M.K. Sixt, D. Kerjaschki, H. Stockinger, Immunology Letters 154 (2013) 31–41.
View | DOI
 
[44]
2013 | Published | Journal Article | IST-REx-ID: 2839 | OA
Interstitial dendritic cell guidance by haptotactic chemokine gradients
M. Weber, R. Hauschild, J. Schwarz, C. Moussion, I. de Vries, D. Legler, S. Luther, M.T. Bollenbach, M.K. Sixt, Science 339 (2013) 328–332.
[Published Version] View | DOI | Download Published Version (ext.)
 
[43]
2012 | Published | Journal Article | IST-REx-ID: 506 | OA
Cell migration: Fibroblasts find a new way to get ahead
M.K. Sixt, Journal of Cell Biology 197 (2012) 347–349.
[Published Version] View | Files available | DOI
 
[42]
2012 | Published | Journal Article | IST-REx-ID: 3158 | OA
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
H. Schachtner, A. Li, D. Stevenson, S. Calaminus, S. Thomas, S. Watson, M.K. Sixt, R. Wedlich Söldner, D. Strathdee, L. Machesky, European Journal of Cell Biology 91 (2012) 923–929.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[41]
2011 | Published | Journal Article | IST-REx-ID: 491
Setting the clock for recirculating lymphocytes
A. Eichner, M.K. Sixt, Science Signaling 4 (2011).
View | DOI
 
[40]
2011 | Published | Journal Article | IST-REx-ID: 518 | OA
CAMTA1 is a novel tumour suppressor regulated by miR-9/9 * in glioblastoma stem cells
D. Schraivogel, L. Weinmann, D. Beier, G. Tabatabai, A. Eichner, J. Zhu, M. Anton, M.K. Sixt, M. Weller, C. Beier, G. Meister, EMBO Journal 30 (2011) 4309–4322.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 
[39]
2011 | Published | Journal Article | IST-REx-ID: 3371 | OA
Cells on the move in Philadelphia
M.K. Sixt, C. Parent, Molecular Biology and Evolution 22 (2011) 724.
[Published Version] View | Files available | DOI
 
[38]
2011 | Published | Journal Article | IST-REx-ID: 3385
Interstitial locomotion of leukocytes
M.K. Sixt, Immunology Letters 138 (2011) 32–34.
View | DOI
 
[37]
2011 | Published | Journal Article | IST-REx-ID: 3392
In vivo analysis of uropod function during physiological T cell trafficking
S. Soriano, M. Hons, K. Schumann, V. Kumar, T. Dennier, R. Lyck, M.K. Sixt, J. Stein, Journal of Immunology 187 (2011) 2356–2364.
View | DOI
 
[36]
2011 | Published | Journal Article | IST-REx-ID: 3505 | OA
In vitro analysis of chemotactic leukocyte migration in 3D environments
M.K. Sixt, T. Lämmermann, Cell Migration 769 (2011) 149–165.
[Published Version] View | DOI | Download Published Version (ext.)
 
[35]
2010 | Published | Journal Article | IST-REx-ID: 3956
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
S. Nourshargh, P. Hordijk, M.K. Sixt, Nature Reviews Molecular Cell Biology 11 (2010) 366–378.
View | DOI
 
[34]
2010 | Published | Journal Article | IST-REx-ID: 3957
Lifeact mice for studying F-actin dynamics
J. Riedl, K. Flynn, A. Raducanu, F.R. Gärtner, G. Beck, M. Bosl, F. Bradke, S. Massberg, A. Aszodi, M.K. Sixt, R. Wedlich Söldner, Nature Methods 7 (2010) 168–169.
View | DOI
 
[33]
2010 | Published | Journal Article | IST-REx-ID: 3958
Extracellular matrix in multiple sclerosis lesions: fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells
H. Mohan, M. Krumbholz, R. Sharma, S. Eisele, A. Junker, M.K. Sixt, J. Newcombe, H. Wekerle, R. Hohlfeld, H. Lassmann, E. Meinl, Brain Pathology 20 (2010) 966–975.
View | DOI
 
[32]
2010 | Published | Journal Article | IST-REx-ID: 3959
Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells
K. Schumann, T. Lämmermann, M. Bruckner, D. Legler, J. Polleux, J. Spatz, G. Schuler, R. Förster, M. Lutz, L. Sorokin, M.K. Sixt, Immunity 32 (2010) 703–713.
View | DOI
 
[31]
2010 | Published | Journal Article | IST-REx-ID: 3960 | OA
MEK signalling tunes actin treadmilling for interstitial lymphocyte migration
M. Weber, M.K. Sixt, EMBO Journal 29 (2010) 2861–2863.
View | DOI | Download (ext.)
 
[30]
2010 | Published | Journal Article | IST-REx-ID: 3961
Mechanisms of force generation and force transmission during interstitial leukocyte migration
J. Renkawitz, M.K. Sixt, EMBO Reports 11 (2010) 744–750.
View | DOI
 
[29]
2009 | Published | Journal Article | IST-REx-ID: 3946 | OA
Analogies in the evolution of individual and social immunity
S. Cremer, M.K. Sixt, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 364 (2009) 129–142.
View | DOI | Download None (ext.)
 
[28]
2009 | Published | Journal Article | IST-REx-ID: 3947
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration (Plenary Paper)
T. Lämmermann, J. Renkawitz, X. Wu, K. Hirsch, C. Brakebusch, M.K. Sixt, Blood 113 (2009) 5703–5710.
View | DOI
 
[27]
2009 | Published | Journal Article | IST-REx-ID: 3948
β1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity
M. Bauer, C. Brakebusch, C. Coisne, M.K. Sixt, H. Wekerle, B. Engelhardt, R. Fässler, PNAS 106 (2009) 1920–1925.
View | DOI
 
[26]
2009 | Published | Journal Article | IST-REx-ID: 3949
Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells
T. Quast, B. Tappertzhofen, C. Schild, J. Grell, N. Czeloth, R. Förster, R. Alon, L. Fraemohs, K. Dreck, C. Weber, T. Lämmermann, M.K. Sixt, W. Kolanus, Blood 113 (2009) 5801–5810.
View | DOI
 
[25]
2009 | Published | Journal Article | IST-REx-ID: 3950
Kindlin-3 is required for β2 integrin-mediated leukocyte adhesion to endothelial cells
M. Moser, M. Bauer, S. Schmid, R. Ruppert, S. Schmidt, M.K. Sixt, H. Wang, M. Sperandio, R. Fässler, Nature Medicine 15 (2009) 300–305.
View | DOI
 
[24]
2009 | Published | Journal Article | IST-REx-ID: 3951
Mechanical modes of 'amoeboid' cell migration
T. Lämmermann, M.K. Sixt, Current Opinion in Cell Biology 21 (2009) 636–644.
View | DOI
 
[23]
2009 | Published | Journal Article | IST-REx-ID: 3952
A fundamental role of mAbp1 in neutrophils: impact on β(2) integrin-mediated phagocytosis and adhesion in vivo
J. Schymeinsky, R. Gerstl, I. Mannigel, K. Niedung, D. Frommhold, K. Panthel, J. Heesemann, M.K. Sixt, T. Quast, W. Kolanus, A. Mocsai, J. Wienands, M. Sperandio, B. Walzog, Blood 114 (2009) 4209–4220.
View | DOI
 
[22]
2009 | Published | Journal Article | IST-REx-ID: 3953
The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo
A. Wolf, K. Eller, R. Zeiser, C. Dürr, U. Gerlach, M.K. Sixt, L. Markut, G. Gastl, A. Rosenkranz, D. Wolf, Journal of Immunology 183 (2009) 3751–3760.
View | DOI
 
[21]
2009 | Published | Journal Article | IST-REx-ID: 3954
Adaptive force transmission in amoeboid cell migration
J. Renkawitz, K. Schumann, M. Weber, T. Lämmermann, H. Pflicke, M. Piel, J. Polleux, J. Spatz, M.K. Sixt, Nature Cell Biology 11 (2009) 1438–1443.
View | DOI
 
[20]
2009 | Published | Journal Article | IST-REx-ID: 3955
Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
H. Pflicke, M.K. Sixt, The Journal of Experimental Medicine 206 (2009) 2925–2935.
View | DOI
 
[19]
2008 | Published | Journal Article | IST-REx-ID: 3939
The microanatomy of T-cell responses
T. Lämmermann, M.K. Sixt, Immunological Reviews 221 (2008) 26–43.
View | DOI
 
[18]
2008 | Published | Journal Article | IST-REx-ID: 3940
The extracellular matrix of the spleen as a potential organizer of immune cell compartments
Z. Lokmic, T. Lämmermann, M.K. Sixt, S. Cardell, R. Hallmann, L. Sorokin, Seminars in Immunology 20 (2008) 4–13.
View | DOI
 
[17]
2008 | Published | Journal Article | IST-REx-ID: 3941
Rapid leukocyte migration by integrin-independent flowing and squeezing
T. Lämmermann, B. Bader, S. Monkley, T. Worbs, R. Wedlich Söldner, K. Hirsch, M. Keller, R. Förster, D. Critchley, R. Fässler, M.K. Sixt, Nature 453 (2008) 51–55.
View | DOI
 
[16]
2008 | Published | Journal Article | IST-REx-ID: 3942
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation
D. Frommhold, A. Ludwig, M.G. Bixel, A. Zarbock, I. Babushkina, M. Weissinger, S. Cauwenberghs, L. Ellies, J. Marth, A. Beck Sickinger, M.K. Sixt, B. Lange Sperandio, A. Zernecke, E. Brandt, C. Weber, D. Vestweber, K. Ley, M. Sperandio, The Journal of Experimental Medicine 205 (2008) 1435–1446.
View | DOI
 
[15]
2008 | Published | Journal Article | IST-REx-ID: 3943
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
K. Kessenbrock, L. Fröhlich, M.K. Sixt, T. Lämmermann, H. Pfister, A. Bateman, A. Belaaouaj, J. Ring, M. Ollert, R. Fässler, D. Jenne, The Journal of Clinical Investigation 118 (2008) 2438–2447.
View | DOI
 
[14]
2008 | Published | Journal Article | IST-REx-ID: 3944
Lifeact: a versatile marker to visualize F-actin
J. Riedl, A. Crevenna, K. Kessenbrock, J. Yu, D. Neukirchen, M. Bista, F. Bradke, D. Jenne, T. Holak, Z. Werb, M.K. Sixt, R. Wedlich Soldner, Nature Methods 5 (2008) 605–607.
View | DOI
 
[13]
2008 | Published | Journal Article | IST-REx-ID: 3945
The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1
C. Tripp, B. Haid, V. Flacher, M.K. Sixt, H. Peter, J. Farkas, R. Gschwentner, L. Sorokin, N. Romani, P. Stoitzner, Immunobiology 213 (2008) 715–28.
View | DOI
 
[12]
2007 | Published | Journal Article | IST-REx-ID: 3937
Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces
E. Woolf, I. Grigorova, A. Sagiv, V. Grabovsky, S. Feigelson, Z. Shulman, T. Hartmann, M.K. Sixt, J. Cyster, R. Alon, Nature Immunology 8 (2007) 1076–1085.
View | DOI
 
[11]
2007 | Published | Journal Article | IST-REx-ID: 3938
RhoH is important for positive thymocyte selection and T-cell receptor signaling
T. Dorn, U. Kuhn, G. Bungartz, S. Stiller, M. Bauer, J. Ellwart, T. Peters, K. Scharffetter Kochanek, M. Semmrich, M. Laschinger, B. Holzmann, W. Klinkert, P. Straten, T. Køllgaard, M.K. Sixt, C. Brakebusch, Blood 109 (2007) 2346–2355.
View | DOI
 
[10]
2006 | Published | Journal Article | IST-REx-ID: 3932
EGF-stimulated migration in ovarian cancer cells is associated with decreased internalization, increased surface expression, and increased shedding of the urokinase plasminogen activator receptor
E. Henic, M.K. Sixt, S. Hansson, G. Høyer Hansen, B. Casslén, Gynecologic Oncology 101 (2006) 28–39.
View | DOI
 
[9]
2006 | Published | Journal Article | IST-REx-ID: 3934
Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules
M. Drumea Mirancea, J. Wessels, C. Müller, M. Essl, J. Eble, E. Tolosa, M. Koch, D. Reinhardt, M.K. Sixt, L. Sorokin, Y. Stierhof, H. Schwarz, G. Klein, Journal of Cell Science 119 (2006) 1396–1405.
View | DOI
 
[8]
2006 | Published | Journal Article | IST-REx-ID: 3935
γ-Parvin is dispensable for hematopoiesis, leukocyte trafficking, and T-cell-dependent antibody response
H. Chu, I. Thievessen, M.K. Sixt, T. Lämmermann, A. Waisman, A. Braun, A. Noegel, R. Fässler, Molecular and Cellular Biology 26 (2006) 1817–1825.
View | DOI
 
[7]
2006 | Published | Journal Article | IST-REx-ID: 3936
β1 integrins: zip codes and signaling relay for blood cells
M.K. Sixt, M. Bauer, T. Lämmermann, R. Fässler, Current Opinion in Cell Biology 18 (2006) 482–490.
View | DOI
 
[6]
2005 | Published | Journal Article | IST-REx-ID: 3933
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
M.K. Sixt, N. Kanazawa, M. Selg, T. Samson, G. Roos, D. Reinhardt, R. Pabst, M. Lutz, L. Sorokin, Immunity 22 (2005) 19–29.
View | DOI
 
[5]
2004 | Published | Journal Article | IST-REx-ID: 3929
HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane
V. Witte, B. Laffert, O. Rosorius, P. Lischka, K. Blume, G. Galler, A. Stilper, D. Willbold, P. D’Aloja, M.K. Sixt, J. Kolanus, M. Ott, W. Kolanus, G. Schuler, A. Baur, Molecular Cell 13 (2004) 179–190.
View | DOI
 
[4]
2004 | Published | Journal Article | IST-REx-ID: 3931
Neurocan-GFP fusion protein: a new approach to detect hyaluronan on tissue sections and living cells
H. Zhang, S. Baader, M.K. Sixt, J. Kappler, U. Rauch, Journal of Histochemistry and Cytochemistry 52 (2004) 915–922.
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[3]
2001 | Published | Journal Article | IST-REx-ID: 3927 | OA
TNF-α-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis
D. Wolf, R. Hallmann, G. Sass, M.K. Sixt, S. Küsters, B. Fregien, C. Trautwein, G. Tiegs, Journal of Immunology 166 (2001) 1300–1307.
View | DOI | Download None (ext.) | PubMed | Europe PMC
 
[2]
2001 | Published | Journal Article | IST-REx-ID: 3928 | OA
Cell adhesion and migration properties of β2-integrin negative polymorphonuclear granulocytes on defined extracellular matrix molecules. Relevance for leukocyte extravasation
M.K. Sixt, R. Hallmann, O. Wendler, K. Scharffetter Kochanek, L. Sorokin, Journal of Biological Chemistry 276 (2001) 18878–18887.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[1]
2001 | Published | Journal Article | IST-REx-ID: 3930 | OA
Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis
M.K. Sixt, B. Engelhardt, F. Pausch, R. Hallmann, O. Wendler, L. Sorokin, Journal of Cell Biology 153 (2001) 933–946.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
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