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33 Publications


2024 | Published | Journal Article | IST-REx-ID: 15250 | OA
Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport
D. Boytsov, G.M. Madej, G. Horn, N. Blaha, T. Köcher, H.H. Sitte, D.E. Siekhaus, C. Ziegler, W. Sandtner, M. Roblek, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 

2023 | Published | Journal Article | IST-REx-ID: 13316 | OA
The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network
J.Y. Toshima, A. Tsukahara, M. Nagano, T. Tojima, D.E. Siekhaus, A. Nakano, J. Toshima, ELife 12 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2023 | Published | Journal Article | IST-REx-ID: 14316 | OA
Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome trafficking pathway
M. Nagano, K. Aoshima, H. Shimamura, D.E. Siekhaus, J.Y. Toshima, J. Toshima, Journal of Cell Science 136 (2023).
[Preprint] View | DOI | Download Preprint (ext.) | PubMed | Europe PMC
 

2022 | Published | Journal Article | IST-REx-ID: 10614 | OA
Fos regulates macrophage infiltration against surrounding tissue resistance by a cortical actin-based mechanism in Drosophila
V. Belyaeva, S. Wachner, A. György, S. Emtenani, I. Gridchyn, M. Akhmanova, M. Linder, M. Roblek, M. Sibilia, D.E. Siekhaus, PLoS Biology 20 (2022) e3001494.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2022 | Published | Journal Article | IST-REx-ID: 10712 | OA
The solute carrier MFSD1 decreases β1 integrin’s activation status and thus tumor metastasis
M. Roblek, J. Bicher, M. van Gogh, A. György, R. Seeböck, B. Szulc, M. Damme, M. Olczak, L. Borsig, D.E. Siekhaus, Frontiers in Oncology 12 (2022).
[Published Version] View | Files available | DOI | WoS
 

2022 | Published | Journal Article | IST-REx-ID: 10713 | OA
Cell division in tissues enables macrophage infiltration
M. Akhmanova, S. Emtenani, D. Krueger, A. György, M. Pereira Guarda, M. Vlasov, F. Vlasov, A. Akopian, A. Ratheesh, S. De Renzis, D.E. Siekhaus, Science 376 (2022) 394–396.
[Preprint] View | DOI | Download Preprint (ext.) | WoS | PubMed | Europe PMC
 

2022 | Published | Journal Article | IST-REx-ID: 10714 | OA
A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis
E.T. Martin, P. Blatt, E. Ngyuen, R. Lahr, S. Selvam, H.A.M. Yoon, T. Pocchiari, S. Emtenani, D.E. Siekhaus, A. Berman, G. Fuchs, P. Rangan, Developmental Cell 57 (2022) 883–900.e10.
[Preprint] View | DOI | Download Preprint (ext.) | WoS
 

2022 | Published | Journal Article | IST-REx-ID: 10918 | OA
Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila
S. Emtenani, E.T. Martin, A. György, J. Bicher, J.-W. Genger, T. Köcher, M. Akhmanova, M. Pereira Guarda, M. Roblek, A. Bergthaler, T.R. Hurd, P. Rangan, D.E. Siekhaus, The Embo Journal 41 (2022).
[Published Version] View | Files available | DOI | WoS
 

2022 | Published | Thesis | IST-REx-ID: 11193 | OA
Transcriptional regulation by Dfos and BMP-signaling support tissue invasion of Drosophila immune cells
S. Wachner, Transcriptional Regulation by Dfos and BMP-Signaling Support Tissue Invasion of Drosophila Immune Cells, Institute of Science and Technology Austria, 2022.
[Published Version] View | Files available | DOI
 

2022 | Published | Journal Article | IST-REx-ID: 12080 | OA
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway
M. Enshoji, Y. Miyano, N. Yoshida, M. Nagano, M. Watanabe, M. Kunihiro, D.E. Siekhaus, J.Y. Toshima, J. Toshima, Journal of Cell Biology 221 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2021 | Published | Journal Article | IST-REx-ID: 10536 | OA
TGFβ signaling in myeloid cells promotes lung and liver metastasis through different mechanisms
C. Stefanescu, M. Van Gogh, M. Roblek, M. Heikenwalder, L. Borsig, Frontiers in Oncology 11 (2021).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2021 | Published | Journal Article | IST-REx-ID: 9363 | OA
Optogenetic delivery of trophic signals in a genetic model of Parkinson's disease
Á. Inglés Prieto, N. Furthmann, S.H. Crossman, A.M. Tichy, N. Hoyer, M. Petersen, V. Zheden, J. Bicher, E. Gschaider-Reichhart, A. György, D.E. Siekhaus, P. Soba, K.F. Winklhofer, H.L. Janovjak, PLoS Genetics 17 (2021) e1009479.
[Published Version] View | Files available | DOI | WoS
 

2020 | Published | Journal Article | IST-REx-ID: 7466 | OA
Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila
K. Kierdorf, F. Hersperger, J. Sharrock, C.M. Vincent, P. Ustaoglu, J. Dou, A. György, O. Groß, D.E. Siekhaus, M.S. Dionne, ELife 9 (2020).
[Published Version] View | Files available | DOI | WoS
 

2020 | Submitted | Preprint | IST-REx-ID: 8557 | OA
Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance
V. Belyaeva, S. Wachner, I. Gridchyn, M. Linder, S. Emtenani, A. György, M. Sibilia, D.E. Siekhaus, BioRxiv (n.d.).
[Preprint] View | Files available | DOI | Download Preprint (ext.)
 

2020 | Published | Thesis | IST-REx-ID: 8983 | OA
Metabolic regulation of Drosophila macrophage tissue invasion
S. Emtenani, Metabolic Regulation of Drosophila Macrophage Tissue Invasion, Institute of Science and Technology Austria, 2020.
[Published Version] View | Files available | DOI
 

2019 | Published | Journal Article | IST-REx-ID: 6187 | OA
A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
K. Valosková, J. Bicher, M. Roblek, S. Emtenani, A. György, M. Misova, A. Ratheesh, P. Rodrigues, K. Shkarina, I.S.B. Larsen, S.Y. Vakhrushev, H. Clausen, D.E. Siekhaus, ELife 8 (2019).
[Published Version] View | Files available | DOI | WoS
 

2019 | Published | Journal Article | IST-REx-ID: 6190 | OA
CCL2 is a vascular permeability factor inducing CCR2-dependent endothelial retraction during lung metastasis
M. Roblek, D. Protsyuk, P.F. Becker, C. Stefanescu, C. Gorzelanny, J.F. Glaus Garzon, L. Knopfova, M. Heikenwalder, B. Luckow, S.W. Schneider, L. Borsig, Molecular Cancer Research 17 (2019) 783–793.
[Published Version] View | DOI | Download Published Version (ext.) | WoS | PubMed | Europe PMC
 

2019 | Published | Journal Article | IST-REx-ID: 8 | OA
The Repo homeodomain transcription factor suppresses hematopoiesis in Drosophila and preserves the glial fate
G. Trébuchet, P.B. Cattenoz, J. Zsámboki, D. Mazaud, D.E. Siekhaus, M. Fanto, A. Giangrande, Journal of Neuroscience 39 (2019) 238–255.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2019 | Published | Thesis | IST-REx-ID: 6546 | OA
The role of a highly conserved major facilitator superfamily member in Drosophila embryonic macrophage migration
K. Valosková, The Role of a Highly Conserved Major Facilitator Superfamily Member in Drosophila Embryonic Macrophage Migration, Institute of Science and Technology Austria, 2019.
[Published Version] View | Files available | DOI
 

2019 | Published | Journal Article | IST-REx-ID: 7097 | OA
Rab5-mediated endosome formation is regulated at the trans-Golgi network
M. Nagano, J.Y. Toshima, D.E. Siekhaus, J. Toshima, Communications Biology 2 (2019).
[Published Version] View | Files available | DOI | WoS
 

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