Please note that ISTA Research Explorer no longer supports Internet Explorer versions 8 or 9 (or earlier).
We recommend upgrading to the latest Internet Explorer, Google Chrome, or Firefox.
115 Publications
2022 | Journal Article | IST-REx-ID: 11588 |

Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo
L. Nicolai, R. Kaiser, R. Escaig, M.L. Hoffknecht, A. Anjum, A. Leunig, J. Pircher, A. Ehrlich, M. Lorenz, H. Ishikawa-Ankerhold, W.C. Aird, S. Massberg, F.R. Gärtner, Haematologica 107 (2022) 1669–1680.
View
| Files available
| DOI
L. Nicolai, R. Kaiser, R. Escaig, M.L. Hoffknecht, A. Anjum, A. Leunig, J. Pircher, A. Ehrlich, M. Lorenz, H. Ishikawa-Ankerhold, W.C. Aird, S. Massberg, F.R. Gärtner, Haematologica 107 (2022) 1669–1680.
2022 | Journal Article | IST-REx-ID: 11843 |

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
View
| Files available
| DOI
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).
2022 | Journal Article | IST-REx-ID: 12085 |

Weak catch bonds make strong networks
Mulla, Yuval, Weak catch bonds make strong networks. Nature Materials 21 (9). 2022
View
| DOI
| Download Preprint (ext.)
| PubMed | Europe PMC
Mulla, Yuval, Weak catch bonds make strong networks. Nature Materials 21 (9). 2022
2022 | Journal Article | IST-REx-ID: 12119 |

Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease
Petzold, Tobias, Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease. Immunity 55 (12). 2022
View
| Files available
| DOI
| PubMed | Europe PMC
Petzold, Tobias, Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease. Immunity 55 (12). 2022
2022 | Journal Article | IST-REx-ID: 12133
Principles of disease defence in organisms, superorganisms and societies
Cremer, Sylvia, Principles of disease defence in organisms, superorganisms and societies. Nature Reviews Immunology 22 (12). 2022
View
| DOI
| PubMed | Europe PMC
Cremer, Sylvia, Principles of disease defence in organisms, superorganisms and societies. Nature Reviews Immunology 22 (12). 2022
2022 | Journal Article | IST-REx-ID: 10703 |

WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
F. Gaertner, P. Reis-Rodrigues, I. de Vries, M. Hons, J. Aguilera, M. Riedl, A.F. Leithner, S. Tasciyan, A. Kopf, J. Merrin, V. Zheden, W. Kaufmann, R. Hauschild, M.K. Sixt, Developmental Cell 57 (2022) 47–62.e9.
View
| Files available
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
F. Gaertner, P. Reis-Rodrigues, I. de Vries, M. Hons, J. Aguilera, M. Riedl, A.F. Leithner, S. Tasciyan, A. Kopf, J. Merrin, V. Zheden, W. Kaufmann, R. Hauschild, M.K. Sixt, Developmental Cell 57 (2022) 47–62.e9.
2022 | Thesis | IST-REx-ID: 12401
Role of microenvironment heterogeneity in cancer cell invasion
S. Tasciyan, Role of Microenvironment Heterogeneity in Cancer Cell Invasion, Institute of Science and Technology Austria, 2022.
View
| Files available
| DOI
S. Tasciyan, Role of Microenvironment Heterogeneity in Cancer Cell Invasion, Institute of Science and Technology Austria, 2022.
2022 | Journal Article | IST-REx-ID: 12272 |

Plan your trip before you leave: The neutrophils’ search-and-run journey
J.A. Stopp, M.K. Sixt, Journal of Cell Biology 221 (2022).
View
| Files available
| DOI
| PubMed | Europe PMC
J.A. Stopp, M.K. Sixt, Journal of Cell Biology 221 (2022).
2022 | Journal Article | IST-REx-ID: 9794 |

Multitier mechanics control stromal adaptations in swelling lymph nodes
F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg, W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology 23 (2022) 1246–1255.
View
| Files available
| DOI
F.P. Assen, J. Abe, M. Hons, R. Hauschild, S. Shamipour, W. Kaufmann, T. Costanzo, G. Krens, M. Brown, B. Ludewig, S. Hippenmeyer, C.-P.J. Heisenberg, W. Weninger, E.B. Hannezo, S.A. Luther, J.V. Stein, M.K. Sixt, Nature Immunology 23 (2022) 1246–1255.
2021 | Journal Article | IST-REx-ID: 10834 |

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
View
| DOI
| Download Preprint (ext.)
| PubMed | Europe PMC
S. Stahnke, H. Döring, C. Kusch, D.J.J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M.K. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, B. Nieswandt, K. Rottner, T.E.B. Stradal, Current Biology 31 (2021) 2051–2064.e8.
2021 | Journal Article | IST-REx-ID: 9259 |

Shape and function of interstitial chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic endothelium
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
View
| Files available
| DOI
| PubMed | Europe PMC
K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology 12 (2021).
2021 | Journal Article | IST-REx-ID: 9094 |

Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
View
| Files available
| DOI
| PubMed | Europe PMC
A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB, A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
2021 | Journal Article | IST-REx-ID: 8988 |

In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1
C.F. Düllberg, A. Auer, N. Canigova, K. Loibl, M. Loose, PNAS 118 (2021).
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
C.F. Düllberg, A. Auer, N. Canigova, K. Loibl, M. Loose, PNAS 118 (2021).
2021 | Journal Article | IST-REx-ID: 9294 |

Engaging the front wheels to drive through fibrous terrain
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
2021 | Journal Article | IST-REx-ID: 9822 |

Sequential and switchable patterning for studying cellular processes under spatiotemporal control
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
View
| Files available
| DOI
| PubMed | Europe PMC
T. Zisis, J. Schwarz, M. Balles, M. Kretschmer, M. Nemethova, R.P. Chait, R. Hauschild, J. Lange, C.C. Guet, M.K. Sixt, S. Zahler, ACS Applied Materials and Interfaces 13 (2021) 35545–35560.
2021 | Journal Article | IST-REx-ID: 9429 |

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
View
| Files available
| DOI
J. Morandell, L.A. Schwarz, B. Basilico, S. Tasciyan, G.A. Dimchev, A. Nicolas, C.M. Sommer, C. Kreuzinger, C. Dotter, L. Knaus, Z. Dobler, E. Cacci, F.K. Schur, J.G. Danzl, G. Novarino, Nature Communications 12 (2021).
2021 | Thesis | IST-REx-ID: 10307 |

Pathogenic Escherichia coli hijack the host immune response
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, IST Austria, 2021.
View
| Files available
| DOI
K. Tomasek, Pathogenic Escherichia Coli Hijack the Host Immune Response, IST Austria, 2021.
2021 | Preprint | IST-REx-ID: 10316 |

Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
View
| Files available
| DOI
| Download Preprint (ext.)
K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, BioRxiv (n.d.).
2020 | Journal Article | IST-REx-ID: 7875 |

Microtubules control cellular shape and coherence in amoeboid migrating cells
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
View
| Files available
| DOI
| PubMed | Europe PMC
A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).
2020 | Journal Article | IST-REx-ID: 7876 |

T cells: Bridge-and-channel commute to the white pulp
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.
View
| DOI
| Download Published Version (ext.)
M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.