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51 Publications

2021 | Published | Journal Article | IST-REx-ID: 9205 |

Cryo-EM grid optimization for membrane proteins
D. Kampjut, J. Steiner, L.A. Sazanov, IScience 24 (2021).

2021 | Published | Journal Article | IST-REx-ID: 15274 |

Cysteine mutants of the major facilitator superfamily-type transporter CcoA provide insight into copper import
B. Khalfaoui-Hassani, P.I. Trasnea, S. Steimle, H.-G. Koch, F. Daldal, MBio 12 (2021).

[Published Version] View | Files available | DOI | PubMed | Europe PMC

2020 | Research Data Reference | IST-REx-ID: 9713

Supporting information
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

[Published Version] View | Files available | DOI

2020 | Research Data Reference | IST-REx-ID: 9878

Movies
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

[Published Version] View | Files available | DOI

2020 | Published | Journal Article | IST-REx-ID: 8579 |

Cu homeostasis in bacteria: The ins and outs
A. Andrei, Y. Öztürk, B. Khalfaoui-Hassani, J. Rauch, D. Marckmann, P.I. Trasnea, F. Daldal, H.-G. Koch, Membranes 10 (2020).

[Published Version] View | Files available | DOI | WoS

2020 | Published | Journal Article | IST-REx-ID: 8581

Cryo-EM structure of the entire mammalian F-type ATP synthase
G. Pinke, L. Zhou, L.A. Sazanov, Nature Structural and Molecular Biology 27 (2020) 1077–1085.

2020 | Published | Journal Article | IST-REx-ID: 8737 |

The coupling mechanism of mammalian respiratory complex I
D. Kampjut, L.A. Sazanov, Science 370 (2020).

2020 | Research Data Reference | IST-REx-ID: 9326 |

Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).

[Published Version] View | Files available | DOI | Download Published Version (ext.)

2020 | Published | Journal Article | IST-REx-ID: 7788 |

NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4−/− mice and Leigh syndrome patients: A stabilizing role for NDUFAF2
M.J.W. Adjobo-Hermans, R. De Haas, P.H.G.M. Willems, A. Wojtala, S.E. Van Emst-De Vries, J.A. Wagenaars, M. Van Den Brand, R.J. Rodenburg, J.A.M. Smeitink, L.G. Nijtmans, L.A. Sazanov, M.R. Wieckowski, W.J.H. Koopman, Biochimica et Biophysica Acta - Bioenergetics 1861 (2020).

2020 | Published | Journal Article | IST-REx-ID: 8040

Charge transfer and chemo-mechanical coupling in respiratory complex I
C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, Journal of the American Chemical Society 142 (2020) 9220–9230.

2020 | Published | Journal Article | IST-REx-ID: 8284 |

Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
J. Steiner, L.A. Sazanov, ELife 9 (2020).

2020 | Published | Journal Article | IST-REx-ID: 8318 |

Key role of quinone in the mechanism of respiratory complex I
J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo, D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).

2020 | Published | Thesis | IST-REx-ID: 8353 |

Biochemical and structural investigation of the Mrp antiporter, an ancestor of complex I
J. Steiner, Biochemical and Structural Investigation of the Mrp Antiporter, an Ancestor of Complex I, Institute of Science and Technology Austria, 2020.

View | Files available | DOI

2020 | Published | Thesis | IST-REx-ID: 8340 |

Molecular mechanisms of mitochondrial redox-coupled proton pumping enzymes
D. Kampjut, Molecular Mechanisms of Mitochondrial Redox-Coupled Proton Pumping Enzymes, Institute of Science and Technology Austria, 2020.

View | Files available | DOI

2019 | Published | Journal Article | IST-REx-ID: 7395 |

Structures of respiratory supercomplex I+III2 reveal functional and conformational crosstalk
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.

2019 | Published | Journal Article | IST-REx-ID: 6352 |

Protective properties of the cultured stem cell proteome studied in an animal model of acetaminophen-induced acute liver failure
A.A. Temnov, K.A. Rogov, A.N. Sklifas, E.V. Klychnikova, M. Hartl, K. Djinovic-Carugo, A. Charnagalov, Molecular Biology Reports (2019).

[Published Version] View | Files available | DOI | WoS

2019 | Published | Journal Article | IST-REx-ID: 6859

Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase
L. Zhou, L.A. Sazanov, Science 365 (2019).

2019 | Published | Journal Article | IST-REx-ID: 6919 |

Structural basis of sterol recognition by human hedgehog receptor PTCH1
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).

[Published Version] View | Files available | DOI | WoS

2019 | Published | Journal Article | IST-REx-ID: 6848 |

Structure and mechanism of mitochondrial proton-translocating transhydrogenase
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.

2018 | Published | Journal Article | IST-REx-ID: 152 |

Mammalian mitochondrial complex I structure and disease causing mutations
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.

[Submitted Version] View | Files available | DOI | WoS

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51 Publications

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