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51 Publications


2019 | Published | Journal Article | IST-REx-ID: 6859 View | Files available | DOI | WoS | PubMed | Europe PMC
 

2019 | Published | Journal Article | IST-REx-ID: 6919 | OA
Structural basis of sterol recognition by human hedgehog receptor PTCH1
C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances 5 (2019).
[Published Version] View | Files available | DOI | WoS
 

2019 | Published | Journal Article | IST-REx-ID: 7395 | OA
Structures of respiratory supercomplex I+III2 reveal functional and conformational crosstalk
J.A. Letts, K. Fiedorczuk, G. Degliesposti, M. Skehel, L.A. Sazanov, Molecular Cell 75 (2019) 1131–1146.e6.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2019 | Published | Journal Article | IST-REx-ID: 6848 | OA
Structure and mechanism of mitochondrial proton-translocating transhydrogenase
D. Kampjut, L.A. Sazanov, Nature 573 (2019) 291–295.
[Submitted Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

2018 | Published | Journal Article | IST-REx-ID: 152 | OA
Mammalian mitochondrial complex I structure and disease causing mutations
K. Fiedorczuk, L.A. Sazanov, Trends in Cell Biology 28 (2018) 835–867.
[Submitted Version] View | Files available | DOI | WoS
 

2017 | Published | Book Chapter | IST-REx-ID: 444
Structure of respiratory complex I: “Minimal” bacterial and “de luxe” mammalian versions
L.A. Sazanov, in:, M. Wikström (Ed.), Mechanisms of Primary Energy Transduction in Biology , Royal Society of Chemistry, 2017, pp. 25–59.
View | DOI
 

2017 | Published | Journal Article | IST-REx-ID: 515 | OA
Clarifying the supercomplex: The higher-order organization of the mitochondrial electron transport chain
J.A. Letts, L.A. Sazanov, Nature Structural and Molecular Biology 24 (2017) 800–808.
[Submitted Version] View | Files available | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1232
The architecture of respiratory supercomplexes
J.A. Letts, K. Fiedorczuk, L.A. Sazanov, Nature 537 (2016) 644–648.
View | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1276 | OA
Atomistic determinants of co-enzyme Q reduction at the Qi-site of the cytochrome bc1 complex
P. Postila, K. Kaszuba, P. Kuleta, I. Vattulainen, M. Sarewicz, A. Osyczka, T. Róg, Scientific Reports 6 (2016).
[Published Version] View | Files available | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1288
Reversible FMN dissociation from Escherichia coli respiratory complex I
P. Holt, R. Efremov, E. Nakamaru Ogiso, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 1777–1785.
View | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1186 | OA
Modular architecture and unique teichoic acid recognition features of choline-binding protein L CbpL contributing to pneumococcal pathogenesis
J. Gutierrez-Fernandez, M. Saleh, M. Alcorlo, A. Gómez Mejóa, D. Pantoja Uceda, M. Treviño, F. Vob, M. Abdullah, S. Galán Bartual, J. Seinen, P. Sánchez Murcia, F. Gago, M. Bruix, S. Hammerschmidt, J. Hermoso, Scientific Reports 6 (2016).
[Published Version] View | Files available | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1521
Structure of bacterial respiratory complex I
J. Berrisford, R. Baradaran, L.A. Sazanov, Biochimica et Biophysica Acta - Bioenergetics 1857 (2016) 892–901.
View | DOI
 

2016 | Published | Journal Article | IST-REx-ID: 1209 | OA
Purification of ovine respiratory complex i results in a highly active and stable preparation
J.A. Letts, G. Degliesposti, K. Fiedorczuk, M. Skehel, L.A. Sazanov, Journal of Biological Chemistry 291 (2016) 24657–24675.
[Submitted Version] View | DOI | Download Submitted Version (ext.)
 

2016 | Published | Journal Article | IST-REx-ID: 1226 | OA
Atomic structure of the entire mammalian mitochondrial complex i
K. Fiedorczuk, J.A. Letts, G. Degliesposti, K. Kaszuba, M. Skehel, L.A. Sazanov, Nature 538 (2016) 406–410.
[Submitted Version] View | DOI | Download Submitted Version (ext.) | PubMed | Europe PMC
 

2015 | Published | Journal Article | IST-REx-ID: 1683
Gaining mass: The structure of respiratory complex I-from bacterial towards mitochondrial versions
J.A. Letts, L.A. Sazanov, Current Opinion in Structural Biology 33 (2015) 135–145.
View | DOI
 

2015 | Published | Journal Article | IST-REx-ID: 1638
A giant molecular proton pump: structure and mechanism of respiratory complex I
L.A. Sazanov, Nature Reviews Molecular Cell Biology 16 (2015) 375–388.
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