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93 Publications
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2025 | Published | Journal Article | IST-REx-ID: 19453 |

Learning reshapes the hippocampal representation hierarchy
H.S.C. Chiossi, M. Nardin, G. Tkačik, J.L. Csicsvari, Proceedings of the National Academy of Sciences 122 (2025).
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H.S.C. Chiossi, M. Nardin, G. Tkačik, J.L. Csicsvari, Proceedings of the National Academy of Sciences 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 18849 |

Deriving a genetic regulatory network from an optimization principle
T.R. Sokolowski, T. Gregor, W. Bialek, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
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T.R. Sokolowski, T. Gregor, W. Bialek, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 19036 |

Layer-specific control of inhibition by NDNF interneurons
L.B. Naumann, L. Hertäg, J. Müller, J.J. Letzkus, H. Sprekeler, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
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L.B. Naumann, L. Hertäg, J. Müller, J.J. Letzkus, H. Sprekeler, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 19499 |

Hardware-optimal quantum algorithms
S. Muroya Lei, K. Chatterjee, T.A. Henzinger, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
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S. Muroya Lei, K. Chatterjee, T.A. Henzinger, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 18850 |

Chromatin enables precise and scalable gene regulation with factors of limited specificity
M.L. Perkins, J. Crocker, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
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M.L. Perkins, J. Crocker, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 19728 |

Foraging for water by MIZ1-mediated antagonism between root gravitropism and hydrotropism
Y. Zhang, Z. Bao, A. Smoljan, Y. Liu, H. Wang, J. Friml, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
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Y. Zhang, Z. Bao, A. Smoljan, Y. Liu, H. Wang, J. Friml, Proceedings of the National Academy of Sciences of the United States of America 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 19627 |

Privacy for free in the overparameterized regime
S. Bombari, M. Mondelli, Proceedings of the National Academy of Sciences 122 (2025).
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S. Bombari, M. Mondelli, Proceedings of the National Academy of Sciences 122 (2025).
2025 | Published | Journal Article | IST-REx-ID: 19626 |

Pulsatile basal gene expression as a fitness determinant in bacteria
K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, C.C. Guet, Proceedings of the National Academy of Sciences 122 (2025).
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K. Jain, R. Hauschild, O. Bochkareva, R. Römhild, G. Tkačik, C.C. Guet, Proceedings of the National Academy of Sciences 122 (2025).
2024 | Published | Journal Article | IST-REx-ID: 15116 |

Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration
G. Giubertoni, L. Feng, K. Klein, G. Giannetti, L. Rutten, Y. Choi, A. Van Der Net, G. Castro-Linares, F. Caporaletti, D. Micha, J. Hunger, A. Deblais, D. Bonn, N. Sommerdijk, A. Šarić, I.M. Ilie, G.H. Koenderink, S. Woutersen, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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G. Giubertoni, L. Feng, K. Klein, G. Giannetti, L. Rutten, Y. Choi, A. Van Der Net, G. Castro-Linares, F. Caporaletti, D. Micha, J. Hunger, A. Deblais, D. Bonn, N. Sommerdijk, A. Šarić, I.M. Ilie, G.H. Koenderink, S. Woutersen, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 15250 |

Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport
D. Boytsov, G.M. Madej, G. Horn, N. Blaha, T. Köcher, H.H. Sitte, D.E. Siekhaus, C. Ziegler, W. Sandtner, M. Roblek, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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D. Boytsov, G.M. Madej, G. Horn, N. Blaha, T. Köcher, H.H. Sitte, D.E. Siekhaus, C. Ziegler, W. Sandtner, M. Roblek, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 18479 |

Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes
Y. Mcdonough, F. Ruzicka, T. Connallon, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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Y. Mcdonough, F. Ruzicka, T. Connallon, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 18526 |

Endosomal membrane budding patterns in plants
E. Weiner, E. Berryman, F.F. Frey, A.G. Solís, A. Leier, T.M. Lago, A. Šarić, M.S. Otegui, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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E. Weiner, E. Berryman, F.F. Frey, A.G. Solís, A. Leier, T.M. Lago, A. Šarić, M.S. Otegui, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 14841 |

A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction
J. Clatot, C. Currin, Q. Liang, T. Pipatpolkai, S.L. Massey, I. Helbig, L. Delemotte, T.P. Vogels, M. Covarrubias, E.M. Goldberg, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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J. Clatot, C. Currin, Q. Liang, T. Pipatpolkai, S.L. Massey, I. Helbig, L. Delemotte, T.P. Vogels, M. Covarrubias, E.M. Goldberg, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 15001 |

Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites
S. Curk, J. Krausser, G. Meisl, D. Frenkel, S. Linse, T.C.T. Michaels, T.P.J. Knowles, A. Šarić, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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S. Curk, J. Krausser, G. Meisl, D. Frenkel, S. Linse, T.C.T. Michaels, T.P.J. Knowles, A. Šarić, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 15084 |

GABAB receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles
P. Koppensteiner, P. Bhandari, C. Önal, C. Borges Merjane, E. Le Monnier, U. Roy, Y. Nakamura, T. Sadakata, M. Sanbo, M. Hirabayashi, J. Rhee, N. Brose, P.M. Jonas, R. Shigemoto, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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P. Koppensteiner, P. Bhandari, C. Önal, C. Borges Merjane, E. Le Monnier, U. Roy, Y. Nakamura, T. Sadakata, M. Sanbo, M. Hirabayashi, J. Rhee, N. Brose, P.M. Jonas, R. Shigemoto, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 14478 |

Frequent horizontal chromosome transfer between asexual fungal insect pathogens
M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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M. Habig, A.V. Grasse, J. Müller, E.H. Stukenbrock, H. Leitner, S. Cremer, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 18108 |

Commutative avatars of representations of semisimple Lie groups
T. Hausel, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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T. Hausel, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 18525 |

Quantitative omnigenic model discovers interpretable genome-wide associations
N. Ruzickova, M. Hledik, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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N. Ruzickova, M. Hledik, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 18703 |

Density amplifiers of cooperation for spatial games
J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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J. Svoboda, K. Chatterjee, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
2024 | Published | Journal Article | IST-REx-ID: 17123 |

Information content and optimization of self-organized developmental systems
D. Brückner, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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D. Brückner, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).
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